Loxodonta africana (African savanna elephant): 100654493
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Entry
100654493 CDS
T04351
Gene name
TLR4
Definition
(RefSeq) toll-like receptor 4
KO
K10160
toll-like receptor 4
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04064
NF-kappa B signaling pathway
lav04066
HIF-1 signaling pathway
lav04145
Phagosome
lav04151
PI3K-Akt signaling pathway
lav04217
Necroptosis
lav04613
Neutrophil extracellular trap formation
lav04620
Toll-like receptor signaling pathway
lav04621
NOD-like receptor signaling pathway
lav05132
Salmonella infection
lav05133
Pertussis
lav05134
Legionellosis
lav05135
Yersinia infection
lav05140
Leishmaniasis
lav05142
Chagas disease
lav05144
Malaria
lav05145
Toxoplasmosis
lav05146
Amoebiasis
lav05152
Tuberculosis
lav05161
Hepatitis B
lav05162
Measles
lav05164
Influenza A
lav05170
Human immunodeficiency virus 1 infection
lav05171
Coronavirus disease - COVID-19
lav05205
Proteoglycans in cancer
lav05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
lav05321
Inflammatory bowel disease
lav05323
Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
100654493 (TLR4)
04066 HIF-1 signaling pathway
100654493 (TLR4)
04151 PI3K-Akt signaling pathway
100654493 (TLR4)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
100654493 (TLR4)
09143 Cell growth and death
04217 Necroptosis
100654493 (TLR4)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
100654493 (TLR4)
04620 Toll-like receptor signaling pathway
100654493 (TLR4)
04621 NOD-like receptor signaling pathway
100654493 (TLR4)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100654493 (TLR4)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100654493 (TLR4)
09163 Immune disease
05323 Rheumatoid arthritis
100654493 (TLR4)
05321 Inflammatory bowel disease
100654493 (TLR4)
09171 Infectious disease: bacterial
05132 Salmonella infection
100654493 (TLR4)
05135 Yersinia infection
100654493 (TLR4)
05133 Pertussis
100654493 (TLR4)
05134 Legionellosis
100654493 (TLR4)
05152 Tuberculosis
100654493 (TLR4)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100654493 (TLR4)
05161 Hepatitis B
100654493 (TLR4)
05171 Coronavirus disease - COVID-19
100654493 (TLR4)
05164 Influenza A
100654493 (TLR4)
05162 Measles
100654493 (TLR4)
09174 Infectious disease: parasitic
05146 Amoebiasis
100654493 (TLR4)
05144 Malaria
100654493 (TLR4)
05145 Toxoplasmosis
100654493 (TLR4)
05140 Leishmaniasis
100654493 (TLR4)
05142 Chagas disease
100654493 (TLR4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
lav04131
]
100654493 (TLR4)
09183 Protein families: signaling and cellular processes
04054 Pattern recognition receptors [BR:
lav04054
]
100654493 (TLR4)
04090 CD molecules [BR:
lav04090
]
100654493 (TLR4)
00536 Glycosaminoglycan binding proteins [BR:
lav00536
]
100654493 (TLR4)
Membrane trafficking [BR:
lav04131
]
Endocytosis
Phagocytosis
Toll-like receptors
100654493 (TLR4)
Pattern recognition receptors [BR:
lav04054
]
Membrane-bound pattern recognition receptors
Toll-like receptors
100654493 (TLR4)
CD molecules [BR:
lav04090
]
Proteins
100654493 (TLR4)
Glycosaminoglycan binding proteins [BR:
lav00536
]
Hyaluronan
Cell surface receptors
100654493 (TLR4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
LRR_8
TIR
LRR_4
TIR_2
LRR_5
LRR_1
LRR_9
DUF1863
LRRCT
Motif
Other DBs
NCBI-GeneID:
100654493
NCBI-ProteinID:
XP_003407827
UniProt:
G3SYU3
LinkDB
All DBs
Position
Unknown
AA seq
841 aa
AA seq
DB search
MMPVSRLAGALIPAMTFLSYLRVESWEPCVEVIPNISYRCMEVNLYKIPDNIPSSAKNLD
LSFNPLRHLGSHSFSNFSELQVLDLSRCEIQIIEDGAYWGLNHLFTLILTGNPIQHLALG
TFFGLSGLQKLVAVEINLTSLEDFPIGHLKTLKELNVAHNSIHSFKLPEYFSNLSNLEHL
DLSNNQIRNIFRKDLQILHQIPLLNLSLDLSLNMIDFIQPGAFKEIRLHKLTLRSNFDNM
TVMKMCIQGLAGLEVHQLVMGEFKNERNLDRFDKSALEGLCNLTIEEFRMAYVSDFSSHD
IDVFNCLANVSAVSLVSLNLNELERFPEDYRWQSLELVNCKLQPFPALALSSLKRFVLTA
NKNSNTIVEFKLPSLEFLDLSGNVLSLRGCCSQSDFGTTKLKYLDLSFNNVIVMNSNFLG
LEQLKHLDFRYSTLKHVNDFPPFLSLTKLLYLDISHTHIHVVFHGIFLGLYSLKVLKMAG
NSFQDNFLPDIFTDLTDLIFLDLSYCQLEQVSRGAFDSLLRLQVINMSSNNLLSLDTLPF
KYLHSLQVLDCSFNHIVASKVQELQHLPSNLTLLNLTQNDFACICEHQSFLQWVKDQRQL
LVEVEQMVCATPSDMHGRPVLSFRNTTCQMSKTVISASVLSVFIVSLMLVLAYKFYFHLM
LLAGCRRYGGGECTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIA
ANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSHAGIIFIILQKVEKSLL
RQQVELYRLLNRNTYLEWEDSVLGKHIFWRRLRKALLAGKPWNPEGTADAENNQLEATTF
T
NT seq
2526 nt
NT seq
+upstream
nt +downstream
nt
atgatgcctgtctcacgcctggctggggctctgataccagccatgaccttcctctcctac
ttgagagtggagagctgggagccctgcgtggaggtaattcctaacatttcttaccgatgc
atggaggtgaatctctacaaaatacctgacaacattccctcatcagccaagaacctggat
ctgagctttaaccccctgaggcacttaggtagccatagcttctccaacttctcagaactg
caggtgctggatttatccaggtgtgaaattcagataattgaagatggtgcatattgggga
ctaaatcatctcttcaccttgatattaacgggaaaccctatccagcatttagccctggga
accttttttggactatcaggtttgcaaaagctggtggctgtggagataaacctaacctct
ctagaggacttccccattgggcatcttaaaactttgaaggagcttaatgtagctcacaat
tctatccattccttcaaattacctgaatatttttctaacctgtccaacctggaacacttg
gacctttccaataaccagatccgaaatatttttcgtaaagacttgcagatcctacatcaa
attcctctactcaatctctctctagacctgtccctgaacatgatagactttatccaacca
ggtgccttcaaagaaattaggcttcataaactgactttgagaagcaattttgataatatg
actgtaatgaaaatgtgtattcaaggtctggctggtttagaagtccatcagttggtcatg
ggagaatttaaaaatgaaaggaacttggacaggtttgacaaatctgctctggagggacta
tgcaatttgacaattgaagaattccggatggcatatgtcagcgacttctcatcacatgat
attgatgtatttaattgcttggcaaatgtttctgcagtttctctggtgagtctgaatcta
aatgagttagaaagatttcctgaagattacagatggcaatccttagaactggttaactgt
aaacttcaaccatttcctgcactggcactttcctctctgaaaagatttgttttaactgcc
aataaaaatagtaacactattgtcgagtttaaactaccaagccttgagtttctagatctc
agtggaaatgtattgagtctcagaggttgttgttctcagtctgattttgggacaaccaag
ctgaagtatttagatctgagcttcaataatgttattgtcatgaattcaaacttcctgggc
ttggaacaactaaaacatctagatttccgatattccaccttgaaacatgtcaatgatttt
ccaccatttctatcactcacaaaactactttaccttgacatttctcacacccatattcac
gttgtcttccacggcatctttcttggcttgtatagcctcaaagtcttaaaaatggctggc
aattcttttcaggacaacttccttccagatatcttcacagatctgactgacttgattttc
ttggacctctcttactgccaactggaacaggtgtcccgaggagcttttgactcacttctc
agactacaggtgataaatatgagttccaacaacctcctgtccttggatacacttcccttt
aaatatctccactcgcttcaagttctagactgtagtttcaatcatatagtggcctccaag
gtacaagaactacaacatcttccaagtaacctaactctcttaaatcttacccagaatgac
tttgcttgtatttgtgagcaccagagtttcctgcagtgggtcaaggaccagaggcagctc
ttggtggaagttgaacaaatggtgtgtgcgacaccttcagacatgcacggcaggcctgtg
ctgagttttaggaacaccacctgtcagatgagtaagactgttatcagtgcgtcagttctc
agtgtgttcatagtatctctgatgctagttttggcctataagttctatttccacctgatg
cttcttgcaggctgcagaagatatggtggcggcgaatgcacctatgatgcctttgttatc
tactctagccaggatgaggactgggtgaggaatgagctggtaaagaacctggaagaggga
gtgcccccctttcagctctgccttcactatagagactttatcccaggtgtggccatcgcc
gccaacatcatccaggaaggtttccacaaaagccggaaagttattgtcgtggtgtctcag
cacttcatccagagccgctggtgtatcttcgagtatgagattgcccagacctggcagttt
ttgagcagtcatgctggcattatcttcatcatcctgcagaaggtggagaagtccctgctc
cggcagcaggtggagctgtaccgccttctcaacaggaacacctacctggagtgggaggac
agtgtcctgggaaaacacatcttctggagacgtctcagaaaagccctgttagctgggaaa
ccatggaatccagaaggaacagcagatgcagagaacaaccagcttgaagcaacaactttt
acctga
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integrated database retrieval system
