Loxodonta africana (African savanna elephant): 100665537
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Entry
100665537 CDS
T04351
Gene name
PRKCA
Definition
(RefSeq) protein kinase C alpha type isoform X1
KO
K02677
classical protein kinase C alpha type [EC:
2.7.11.13
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav01521
EGFR tyrosine kinase inhibitor resistance
lav04010
MAPK signaling pathway
lav04012
ErbB signaling pathway
lav04014
Ras signaling pathway
lav04015
Rap1 signaling pathway
lav04020
Calcium signaling pathway
lav04066
HIF-1 signaling pathway
lav04070
Phosphatidylinositol signaling system
lav04071
Sphingolipid signaling pathway
lav04072
Phospholipase D signaling pathway
lav04150
mTOR signaling pathway
lav04151
PI3K-Akt signaling pathway
lav04261
Adrenergic signaling in cardiomyocytes
lav04270
Vascular smooth muscle contraction
lav04310
Wnt signaling pathway
lav04360
Axon guidance
lav04370
VEGF signaling pathway
lav04510
Focal adhesion
lav04540
Gap junction
lav04613
Neutrophil extracellular trap formation
lav04650
Natural killer cell mediated cytotoxicity
lav04664
Fc epsilon RI signaling pathway
lav04666
Fc gamma R-mediated phagocytosis
lav04670
Leukocyte transendothelial migration
lav04713
Circadian entrainment
lav04720
Long-term potentiation
lav04723
Retrograde endocannabinoid signaling
lav04724
Glutamatergic synapse
lav04725
Cholinergic synapse
lav04726
Serotonergic synapse
lav04727
GABAergic synapse
lav04728
Dopaminergic synapse
lav04730
Long-term depression
lav04750
Inflammatory mediator regulation of TRP channels
lav04911
Insulin secretion
lav04912
GnRH signaling pathway
lav04916
Melanogenesis
lav04918
Thyroid hormone synthesis
lav04919
Thyroid hormone signaling pathway
lav04921
Oxytocin signaling pathway
lav04925
Aldosterone synthesis and secretion
lav04926
Relaxin signaling pathway
lav04928
Parathyroid hormone synthesis, secretion and action
lav04929
GnRH secretion
lav04933
AGE-RAGE signaling pathway in diabetic complications
lav04935
Growth hormone synthesis, secretion and action
lav04960
Aldosterone-regulated sodium reabsorption
lav04961
Endocrine and other factor-regulated calcium reabsorption
lav04970
Salivary secretion
lav04971
Gastric acid secretion
lav04972
Pancreatic secretion
lav05017
Spinocerebellar ataxia
lav05022
Pathways of neurodegeneration - multiple diseases
lav05031
Amphetamine addiction
lav05032
Morphine addiction
lav05143
African trypanosomiasis
lav05146
Amoebiasis
lav05161
Hepatitis B
lav05163
Human cytomegalovirus infection
lav05164
Influenza A
lav05170
Human immunodeficiency virus 1 infection
lav05171
Coronavirus disease - COVID-19
lav05200
Pathways in cancer
lav05205
Proteoglycans in cancer
lav05206
MicroRNAs in cancer
lav05214
Glioma
lav05223
Non-small cell lung cancer
lav05225
Hepatocellular carcinoma
lav05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100665537 (PRKCA)
04012 ErbB signaling pathway
100665537 (PRKCA)
04014 Ras signaling pathway
100665537 (PRKCA)
04015 Rap1 signaling pathway
100665537 (PRKCA)
04310 Wnt signaling pathway
100665537 (PRKCA)
04370 VEGF signaling pathway
100665537 (PRKCA)
04066 HIF-1 signaling pathway
100665537 (PRKCA)
04020 Calcium signaling pathway
100665537 (PRKCA)
04070 Phosphatidylinositol signaling system
100665537 (PRKCA)
04072 Phospholipase D signaling pathway
100665537 (PRKCA)
04071 Sphingolipid signaling pathway
100665537 (PRKCA)
04151 PI3K-Akt signaling pathway
100665537 (PRKCA)
04150 mTOR signaling pathway
100665537 (PRKCA)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100665537 (PRKCA)
04540 Gap junction
100665537 (PRKCA)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
100665537 (PRKCA)
04650 Natural killer cell mediated cytotoxicity
100665537 (PRKCA)
04664 Fc epsilon RI signaling pathway
100665537 (PRKCA)
04666 Fc gamma R-mediated phagocytosis
100665537 (PRKCA)
04670 Leukocyte transendothelial migration
100665537 (PRKCA)
09152 Endocrine system
04911 Insulin secretion
100665537 (PRKCA)
04929 GnRH secretion
100665537 (PRKCA)
04912 GnRH signaling pathway
100665537 (PRKCA)
04921 Oxytocin signaling pathway
100665537 (PRKCA)
04926 Relaxin signaling pathway
100665537 (PRKCA)
04935 Growth hormone synthesis, secretion and action
100665537 (PRKCA)
04918 Thyroid hormone synthesis
100665537 (PRKCA)
04919 Thyroid hormone signaling pathway
100665537 (PRKCA)
04928 Parathyroid hormone synthesis, secretion and action
100665537 (PRKCA)
04916 Melanogenesis
100665537 (PRKCA)
04925 Aldosterone synthesis and secretion
100665537 (PRKCA)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100665537 (PRKCA)
04270 Vascular smooth muscle contraction
100665537 (PRKCA)
09154 Digestive system
04970 Salivary secretion
100665537 (PRKCA)
04971 Gastric acid secretion
100665537 (PRKCA)
04972 Pancreatic secretion
100665537 (PRKCA)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
100665537 (PRKCA)
04961 Endocrine and other factor-regulated calcium reabsorption
100665537 (PRKCA)
09156 Nervous system
04724 Glutamatergic synapse
100665537 (PRKCA)
04727 GABAergic synapse
100665537 (PRKCA)
04725 Cholinergic synapse
100665537 (PRKCA)
04728 Dopaminergic synapse
100665537 (PRKCA)
04726 Serotonergic synapse
100665537 (PRKCA)
04720 Long-term potentiation
100665537 (PRKCA)
04730 Long-term depression
100665537 (PRKCA)
04723 Retrograde endocannabinoid signaling
100665537 (PRKCA)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100665537 (PRKCA)
09158 Development and regeneration
04360 Axon guidance
100665537 (PRKCA)
09159 Environmental adaptation
04713 Circadian entrainment
100665537 (PRKCA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100665537 (PRKCA)
05206 MicroRNAs in cancer
100665537 (PRKCA)
05205 Proteoglycans in cancer
100665537 (PRKCA)
05231 Choline metabolism in cancer
100665537 (PRKCA)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100665537 (PRKCA)
05214 Glioma
100665537 (PRKCA)
05223 Non-small cell lung cancer
100665537 (PRKCA)
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
100665537 (PRKCA)
05022 Pathways of neurodegeneration - multiple diseases
100665537 (PRKCA)
09165 Substance dependence
05031 Amphetamine addiction
100665537 (PRKCA)
05032 Morphine addiction
100665537 (PRKCA)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100665537 (PRKCA)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100665537 (PRKCA)
05161 Hepatitis B
100665537 (PRKCA)
05171 Coronavirus disease - COVID-19
100665537 (PRKCA)
05164 Influenza A
100665537 (PRKCA)
05163 Human cytomegalovirus infection
100665537 (PRKCA)
09174 Infectious disease: parasitic
05146 Amoebiasis
100665537 (PRKCA)
05143 African trypanosomiasis
100665537 (PRKCA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100665537 (PRKCA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100665537 (PRKCA)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
lav04131
]
100665537 (PRKCA)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.13 protein kinase C
100665537 (PRKCA)
Protein kinases [BR:
lav01001
]
Serine/threonine kinases: AGC group
PKC family [OT]
100665537 (PRKCA)
Membrane trafficking [BR:
lav04131
]
Endocytosis
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
100665537 (PRKCA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
C1_1
C2
Pkinase_C
C1_2
Kinase-like
APH
Motif
Other DBs
NCBI-GeneID:
100665537
NCBI-ProteinID:
XP_003417343
UniProt:
G3SWW4
LinkDB
All DBs
Position
Unknown
AA seq
671 aa
AA seq
DB search
MADVFPSNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLRVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNEAFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNME
LRQKFEKAKLGPAGNKVISPSEDRKPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGT
EELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVN
GGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIAD
FGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYAKSVDWWAYGVLLYEMLAGQPPFDGE
DEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRID
WEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNP
QFMHPILQSAV
NT seq
2016 nt
NT seq
+upstream
nt +downstream
nt
atggctgacgttttcccgtccaacgactccacggcgtctcaggacgtggccaaccggttc
gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt
gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgag
tttgttactttttcttgcccgggtgccgataagggacctgacactgacgacccaaggagc
aagcacaaatttaaaatccacacttatggaagccccaccttctgtgatcattgtgggtca
ttgctgtacggactcattcaccaagggatgaaatgtgacacctgcgacatgaacgttcac
aagcagtgtgtaataaatgtccccagcctctgtggaatggatcacacagagaagagaggg
cgaatttacctgaaggctgaagttgctgatgagaagctccgcgtcacagtacgagatgca
aaaaatctaatccctatggatccaaatgggctttcagatccttacgtgaagctgaaactt
attcctgatcctaagaatgaaagcaaacaaaaaaccaaaaccatccgctctacactaaac
cctcagtggaatgaggccttcacattcaaattaaagccttcagacaaagaccgacgattg
tctgtagaaatctgggactgggatcgaacaacaagaaatgacttcatgggatccctttcc
tttggagtttcagagctgatgaagatgccggccagtggatggtacaagttgcttaaccaa
gaagaaggtgagtactacaatgtacccattccagaaggggatgaagaaggaaatatggag
ctcaggcagaaatttgagaaagccaagcttggccccgctgggaacaaagtgatcagtcct
tcagaagataggaaaccttccaacaacctggatcgagtaaaactcacggacttcaatttc
ctcatggtcctagggaaggggagttttggaaaggtgatgcttgctgacaggaagggcaca
gaagagctgtatgctatcaagattctcaagaaggacgtggtgatccaggatgacgacgtg
gagtgcaccatggtggagaagcgagttctggccctgctcgacaagcctccattcctgacg
cagctccactcctgcttccagacagtggatcgcctgtacttcgtcatggagtatgtcaac
ggtggggacctcatgtaccacattcagcaagtcgggaaatttaaggagccacaagcagta
ttctatgcagcagagatttccattggattgttctttcttcataaaagaggaatcatttat
agggatctgaaattagataatgtcatgctggattcggaaggacatatcaagattgccgac
tttgggatgtgcaaggagcacatgatggatggcgtcacaaccaggaccttctgtgggact
ccagattatattgccccggagataatcgcttatcagccgtatgcgaaatccgtggactgg
tgggcgtatggcgtcctattatacgaaatgctagctggccagcctccctttgatggcgaa
gatgaagatgaactctttcagtctataatggagcataacgtgtcctatccaaaatccttg
tccaaggaggccgtttccatctgcaaaggactgatgaccaaacaccccgccaagcggctg
ggctgtgggcctgagggtgagagggatgtaagagagcatgccttcttccggagaatcgac
tgggagaaactggagaaccgggagatccagccgccgttcaagcccaaagtgtgtggcaaa
ggagcagaaaactttgacaagttcttcacgcgagggcagcctgtcttaacgccgcctgac
cagctggtcattgctaatatagatcagtctgattttgaagggttctcatatgtcaacccc
cagtttatgcaccccatcttacagagcgcagtatga
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integrated database retrieval system
