KEGG   Loxodonta africana (African savanna elephant): 100671392
Entry
100671392         CDS       T04351                                 

Gene name
TGFBR2
Definition
(RefSeq) TGF-beta receptor type-2 isoform X2
  KO
K04388  TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04010  MAPK signaling pathway
lav04060  Cytokine-cytokine receptor interaction
lav04068  FoxO signaling pathway
lav04144  Endocytosis
lav04218  Cellular senescence
lav04350  TGF-beta signaling pathway
lav04380  Osteoclast differentiation
lav04390  Hippo signaling pathway
lav04520  Adherens junction
lav04659  Th17 cell differentiation
lav04926  Relaxin signaling pathway
lav04933  AGE-RAGE signaling pathway in diabetic complications
lav05142  Chagas disease
lav05161  Hepatitis B
lav05166  Human T-cell leukemia virus 1 infection
lav05200  Pathways in cancer
lav05202  Transcriptional misregulation in cancer
lav05210  Colorectal cancer
lav05212  Pancreatic cancer
lav05220  Chronic myeloid leukemia
lav05225  Hepatocellular carcinoma
lav05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100671392 (TGFBR2)
   04350 TGF-beta signaling pathway
    100671392 (TGFBR2)
   04390 Hippo signaling pathway
    100671392 (TGFBR2)
   04068 FoxO signaling pathway
    100671392 (TGFBR2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100671392 (TGFBR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100671392 (TGFBR2)
  09143 Cell growth and death
   04218 Cellular senescence
    100671392 (TGFBR2)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    100671392 (TGFBR2)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100671392 (TGFBR2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    100671392 (TGFBR2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100671392 (TGFBR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100671392 (TGFBR2)
   05202 Transcriptional misregulation in cancer
    100671392 (TGFBR2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100671392 (TGFBR2)
   05212 Pancreatic cancer
    100671392 (TGFBR2)
   05225 Hepatocellular carcinoma
    100671392 (TGFBR2)
   05226 Gastric cancer
    100671392 (TGFBR2)
   05220 Chronic myeloid leukemia
    100671392 (TGFBR2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100671392 (TGFBR2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100671392 (TGFBR2)
   05161 Hepatitis B
    100671392 (TGFBR2)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    100671392 (TGFBR2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lav01001]
    100671392 (TGFBR2)
Enzymes [BR:lav01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     100671392 (TGFBR2)
Protein kinases [BR:lav01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   100671392 (TGFBR2)
SSDB
Motif
Pfam: ecTbetaR2 PK_Tyr_Ser-Thr Pkinase Pkinase_fungal NAR2 APH
Other DBs
NCBI-GeneID: 100671392
NCBI-ProteinID: XP_003415761
LinkDB
Position
Unknown
AA seq 567 aa
MGRGLLGGLWPLHIVLWTRIASTIPPHVQKPVNDDMMVTDDNGALKLRQLCKFCDVRFST
CDNQKSCMSNCSITSICEKPHEVCVAVWRKNDENITLETVCHDPTIAYHGFVLDDATSSK
CIMKEKKTPGETFFMCSCSAEECNDHIIFSEEYNTSSPDLLLVIIQVTGVSLLPPLGIAI
AVIITFYCYRVHRQQKLSPSWETSKPRKLMEFSEHCAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK
HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH
LHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLHLDPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE
HPCVESMKDNVLRDRGRPEIPSSWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSE
LEHLDRLSGRSCSEEKIPEDGSLNTTK
NT seq 1704 nt   +upstreamnt  +downstreamnt
atgggtcgggggctgctcgggggcctgtggccgctgcacatcgtcctgtggacgcgcatc
gccagcacgatcccgccgcacgttcagaagccggttaatgatgacatgatggtcacggac
gacaatggtgcactcaagctgcggcaactgtgtaaattttgtgacgtgagattttccacc
tgtgacaaccaaaaatcttgtatgagcaactgtagcatcacgtccatctgtgagaaacca
cacgaagtctgtgtggctgtatggagaaagaatgatgagaacataacactagagacagtt
tgccatgaccccaccatcgcctatcatgggtttgtcctggatgatgctacttcttcaaag
tgtattatgaaggagaaaaaaacacctggcgagaccttctttatgtgctcctgtagcgct
gaggagtgcaatgaccacatcatcttctctgaagaatataacaccagcagccctgacttg
ttgttagtcatcatccaagtgacaggcgtcagcctcctgccaccactgggtatcgccata
gctgtgatcatcaccttctactgctaccgcgttcaccgacagcagaagctgagtccatcc
tgggagaccagcaagccaaggaagctcatggagttcagtgagcactgtgccattattctg
gaagatgaccgttcagacatcagctctacctgcgccaacaatatcaaccacaacacggag
ctgctgcccattgagctggataccctggtgggaaagggccgcttcgctgaggtctacaaa
gccaagctgaaacagaacacctcagagcagttcgagaccgtggcagtcaagatcttcccc
tatgaggagtatgcctcctggaagacagagaaggacatcttctcagacatcaacctgaag
catgagaacatactccagttcttgacggctgaagagcggaagacagagctggggaagcag
tattggctgatcaccgccttccatgccaagggcaacctacaggagtacctcacgaggcat
gtcatcagctgggaggacctgcgcaagctgggcagctcccttgctcgaggcattgctcac
ctgcacagtgatcataccccttgcgggaggcccaaaatgcccattgtgcacagggacctc
aagagctccaatatcctcgtgaagaacgacctgacctgctgtctgtgtgacttcgggctt
tccctgcacttggaccccactctatctgtggatgacctggccaacagtgggcaggtggga
actgcaagatacatggccccggaagtccttgaatccaggatgaatttggagaatgttgag
tccttcaagcagaccgatgtctactcgatggctctggtcctctgggaaatgacatctcgc
tgtaatgcggtgggagaagtgaaagattatgagcctccctttggttccaaggtgcgggag
catccctgtgtggaaagcatgaaggacaatgtgttgcgagatcgaggacgaccagaaatt
cccagctcctggctcaaccatcagggcatccagatggtgtgtgagacgctgacggagtgc
tgggaccacgaccctgaggcccgtctcacagcccagtgcgtggcggagcgcttcagtgag
ctggagcacctggacagactctcggggaggagctgctcggaggagaagattccagaagat
ggctcgctgaacactaccaaatag

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