Loxodonta africana (African savanna elephant): 100671392
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Entry
100671392 CDS
T04351
Symbol
TGFBR2
Name
(RefSeq) TGF-beta receptor type-2 isoform X2
KO
K04388
TGF-beta receptor type-2 [EC:
2.7.11.30
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04010
MAPK signaling pathway
lav04060
Cytokine-cytokine receptor interaction
lav04068
FoxO signaling pathway
lav04144
Endocytosis
lav04218
Cellular senescence
lav04350
TGF-beta signaling pathway
lav04380
Osteoclast differentiation
lav04390
Hippo signaling pathway
lav04520
Adherens junction
lav04659
Th17 cell differentiation
lav04926
Relaxin signaling pathway
lav04933
AGE-RAGE signaling pathway in diabetic complications
lav05142
Chagas disease
lav05161
Hepatitis B
lav05166
Human T-cell leukemia virus 1 infection
lav05200
Pathways in cancer
lav05202
Transcriptional misregulation in cancer
lav05210
Colorectal cancer
lav05212
Pancreatic cancer
lav05220
Chronic myeloid leukemia
lav05225
Hepatocellular carcinoma
lav05226
Gastric cancer
lav05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100671392 (TGFBR2)
04350 TGF-beta signaling pathway
100671392 (TGFBR2)
04390 Hippo signaling pathway
100671392 (TGFBR2)
04068 FoxO signaling pathway
100671392 (TGFBR2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
100671392 (TGFBR2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100671392 (TGFBR2)
09143 Cell growth and death
04218 Cellular senescence
100671392 (TGFBR2)
09144 Cellular community - eukaryotes
04520 Adherens junction
100671392 (TGFBR2)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
100671392 (TGFBR2)
09152 Endocrine system
04926 Relaxin signaling pathway
100671392 (TGFBR2)
09158 Development and regeneration
04380 Osteoclast differentiation
100671392 (TGFBR2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100671392 (TGFBR2)
05202 Transcriptional misregulation in cancer
100671392 (TGFBR2)
09162 Cancer: specific types
05210 Colorectal cancer
100671392 (TGFBR2)
05212 Pancreatic cancer
100671392 (TGFBR2)
05225 Hepatocellular carcinoma
100671392 (TGFBR2)
05226 Gastric cancer
100671392 (TGFBR2)
05220 Chronic myeloid leukemia
100671392 (TGFBR2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100671392 (TGFBR2)
05161 Hepatitis B
100671392 (TGFBR2)
09174 Infectious disease: parasitic
05142 Chagas disease
100671392 (TGFBR2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100671392 (TGFBR2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100671392 (TGFBR2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100671392 (TGFBR2)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
100671392 (TGFBR2)
Protein kinases [BR:
lav01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
100671392 (TGFBR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ecTbetaR2
PK_Tyr_Ser-Thr
Pkinase
ABC1
Pkinase_fungal
Haspin_kinase
NAR2
APH
Motif
Other DBs
NCBI-GeneID:
100671392
NCBI-ProteinID:
XP_003415761
LinkDB
All DBs
Position
Unknown
AA seq
567 aa
AA seq
DB search
MGRGLLGGLWPLHIVLWTRIASTIPPHVQKPVNDDMMVTDDNGALKLRQLCKFCDVRFST
CDNQKSCMSNCSITSICEKPHEVCVAVWRKNDENITLETVCHDPTIAYHGFVLDDATSSK
CIMKEKKTPGETFFMCSCSAEECNDHIIFSEEYNTSSPDLLLVIIQVTGVSLLPPLGIAI
AVIITFYCYRVHRQQKLSPSWETSKPRKLMEFSEHCAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK
HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH
LHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLHLDPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE
HPCVESMKDNVLRDRGRPEIPSSWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSE
LEHLDRLSGRSCSEEKIPEDGSLNTTK
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
atgggtcgggggctgctcgggggcctgtggccgctgcacatcgtcctgtggacgcgcatc
gccagcacgatcccgccgcacgttcagaagccggttaatgatgacatgatggtcacggac
gacaatggtgcactcaagctgcggcaactgtgtaaattttgtgacgtgagattttccacc
tgtgacaaccaaaaatcttgtatgagcaactgtagcatcacgtccatctgtgagaaacca
cacgaagtctgtgtggctgtatggagaaagaatgatgagaacataacactagagacagtt
tgccatgaccccaccatcgcctatcatgggtttgtcctggatgatgctacttcttcaaag
tgtattatgaaggagaaaaaaacacctggcgagaccttctttatgtgctcctgtagcgct
gaggagtgcaatgaccacatcatcttctctgaagaatataacaccagcagccctgacttg
ttgttagtcatcatccaagtgacaggcgtcagcctcctgccaccactgggtatcgccata
gctgtgatcatcaccttctactgctaccgcgttcaccgacagcagaagctgagtccatcc
tgggagaccagcaagccaaggaagctcatggagttcagtgagcactgtgccattattctg
gaagatgaccgttcagacatcagctctacctgcgccaacaatatcaaccacaacacggag
ctgctgcccattgagctggataccctggtgggaaagggccgcttcgctgaggtctacaaa
gccaagctgaaacagaacacctcagagcagttcgagaccgtggcagtcaagatcttcccc
tatgaggagtatgcctcctggaagacagagaaggacatcttctcagacatcaacctgaag
catgagaacatactccagttcttgacggctgaagagcggaagacagagctggggaagcag
tattggctgatcaccgccttccatgccaagggcaacctacaggagtacctcacgaggcat
gtcatcagctgggaggacctgcgcaagctgggcagctcccttgctcgaggcattgctcac
ctgcacagtgatcataccccttgcgggaggcccaaaatgcccattgtgcacagggacctc
aagagctccaatatcctcgtgaagaacgacctgacctgctgtctgtgtgacttcgggctt
tccctgcacttggaccccactctatctgtggatgacctggccaacagtgggcaggtggga
actgcaagatacatggccccggaagtccttgaatccaggatgaatttggagaatgttgag
tccttcaagcagaccgatgtctactcgatggctctggtcctctgggaaatgacatctcgc
tgtaatgcggtgggagaagtgaaagattatgagcctccctttggttccaaggtgcgggag
catccctgtgtggaaagcatgaaggacaatgtgttgcgagatcgaggacgaccagaaatt
cccagctcctggctcaaccatcagggcatccagatggtgtgtgagacgctgacggagtgc
tgggaccacgaccctgaggcccgtctcacagcccagtgcgtggcggagcgcttcagtgag
ctggagcacctggacagactctcggggaggagctgctcggaggagaagattccagaagat
ggctcgctgaacactaccaaatag
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