Loxodonta africana (African savanna elephant): 100672245
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Entry
100672245 CDS
T04351
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04217
Necroptosis
lav04380
Osteoclast differentiation
lav04620
Toll-like receptor signaling pathway
lav04621
NOD-like receptor signaling pathway
lav04630
JAK-STAT signaling pathway
lav04658
Th1 and Th2 cell differentiation
lav04659
Th17 cell differentiation
lav05145
Toxoplasmosis
lav05160
Hepatitis C
lav05161
Hepatitis B
lav05162
Measles
lav05164
Influenza A
lav05165
Human papillomavirus infection
lav05167
Kaposi sarcoma-associated herpesvirus infection
lav05168
Herpes simplex virus 1 infection
lav05169
Epstein-Barr virus infection
lav05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100672245 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100672245 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100672245 (TYK2)
04621 NOD-like receptor signaling pathway
100672245 (TYK2)
04658 Th1 and Th2 cell differentiation
100672245 (TYK2)
04659 Th17 cell differentiation
100672245 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
100672245 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
100672245 (TYK2)
05160 Hepatitis C
100672245 (TYK2)
05171 Coronavirus disease - COVID-19
100672245 (TYK2)
05164 Influenza A
100672245 (TYK2)
05162 Measles
100672245 (TYK2)
05168 Herpes simplex virus 1 infection
100672245 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
100672245 (TYK2)
05169 Epstein-Barr virus infection
100672245 (TYK2)
05165 Human papillomavirus infection
100672245 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100672245 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100672245 (TYK2)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100672245 (TYK2)
Protein kinases [BR:
lav01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100672245 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Jak1_Phl
Pkinase
FERM_F2
FERM_F1
SH2_1
Kdo
Kinase-like
ABC1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
100672245
NCBI-ProteinID:
XP_023407665
LinkDB
All DBs
Position
Unknown
AA seq
1046 aa
AA seq
DB search
MPLCRWGATARGSKPDGNGAQPMVSRGVLRVHLHWAGPGGGEPWVTFSEASLTAEEVCIY
IAHKIGITPLCFNLFALFDAQGQVWLPPNHILEVPRDSSLNLHFRMRFYFRNWHGMNPQE
PAVYRCGPPGAESSSDQAEHGLQFLDPASFEYIFEQGKHEFVNDVASLWELSSEEEIHHF
KNESLGMAFLHLCHLALHRGVSLEEVAKKISFKDCIPRSFRSQIQQHNALTRLRLRSIFH
KFLRAFQPSHLSQQLVMVKYLATLERLAPCFATEHIPVCHLELPAQAEGKLCYIQDHGQA
TLDPGKESALGPPTHEVLVTGTGGIQWRPVQAEGSGGSGSGSRNPQANLSGKKAQAQEVD
LQPASRPKGLPWASFCDFQDISHLVVKEHHVSVYCQDNKCLELTLPSRATALSFVSLVDG
YFRLTVDSSHYLCHEVAPPRLVMSIQDGIHGPLLDPFVLAKLQPEDGHYLIHWSSSHLYR
LILTVAQRDQAQGSRSLRLRKFTIEQQAGTFTLEGWDRSFPSVGALRAALQDCSLRVGDD
CFSLRRCCLPLSRELSNLIIMRGPAASTRPLNLSQLSFHRVCREEITQLSHLGQGTRTNV
YEGLLRVKGRDSEEDKEEGGDPLSPSRGSGQELRVVLKVLDPSHHDITLAFYEIASLMSQ
VSHVHLAFVHGICVHGSESECPLPLLIGQLPLIPSPWPVPRPLMAPCLTYEPAQRPSFRI
ILRDLTRLQPHNLVDVSAVSPDLPASDPTVFHKRYLKKIRELGEGHFGKVSLYCYDPTND
GTGEMVAVKSLKAGCGPQLRSGWKREIDILRRLYHEHIVKYKGCCEDPGEKSVQLVMEYV
PLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD
FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVTLYELLTRCDFS
QSPPLKFIELLGLTQGQMTVLRLTELLERGERLPRPEACPCEIYYLMKNCWEAEASFRPT
FQNLIPILKTVHEKYQGQAPSVFSMC
NT seq
3141 nt
NT seq
+upstream
nt +downstream
nt
atgccactgtgccggtggggagccaccgcccgtggcagcaagcctgatgggaacggagct
cagcctatggtcagcaggggagtcctgagggtacacctgcactgggctggccccggtggt
ggggagccctgggtcaccttcagcgaagcctcactgacagccgaggaggtctgcatctac
atcgcacacaaaatcggcatcactccactctgcttcaatctgttcgccctctttgatgcc
cagggccaagtctggctacccccaaaccacatcctggaggtccccagagactccagcctg
aatctgcacttccgcatgaggttttatttccggaactggcatggcatgaaccctcaggag
ccagctgtgtaccgctgtgggccccctggggccgagtcttcctcagatcaagcagagcat
gggctgcaattcttagatccagcctcctttgaatatatctttgagcagggcaagcatgag
tttgtcaatgacgtggcctcactgtgggagctgtccagcgaggaggagatccaccacttt
aagaatgagagcctgggcatggcttttctgcacctctgccaccttgctctccaccgcggt
gtctccctggaggaggtggctaaaaagatcagcttcaaagactgcatcccacgttccttc
cggagccagatccagcagcacaacgcgctgacgcgactgcgcctgcgtagcatcttccac
aagttcctgcgagccttccagcccagccatctctcccagcagctcgtcatggtcaagtac
ctggccacgctcgagcggctggcgccctgctttgccactgagcacataccggtatgccac
ctggagctgccggcccaggctgaggggaagctgtgctacatccaggaccacgggcaggcc
actctggaccccggaaaggagtctgccctgggacccccaacccacgaggtgctggtgaca
ggcaccgggggcattcagtggcggccggtacaggcagagggctctggtggcagcggcagt
ggcagcaggaatcctcaagccaacctttctgggaagaaagcccaggctcaggaggtggac
ctccagccagcgagcaggccaaaggggctgccctgggcctctttctgtgacttccaggac
atcagccacctggtagtgaaggagcaccatgtcagcgtctactgtcaggacaacaagtgc
ctggagctgactctgccctcccgggccacggccctgtccttcgtgtcactggtggatggc
tatttccgcctgacggtcgactcaagccactacctgtgccatgaggtggctcccccacgg
ctggtgatgagtatccaggatgggatccacggacctttgctggatccatttgtgctggcc
aagctccagcccgaggacggtcactacctcatccattggagtagcagccacctctaccgc
cttatcctcaccgtggcccagcgtgaccaggcacaaggctcacggagcttgcgcttacgg
aagttcaccatcgagcagcaggctgggacctttacactggagggctgggaccggtccttt
cccagtgtaggggcactacgggccgccctgcaggactgctcactgcgtgttggggatgac
tgcttctccctgcggcgctgctgcctgccactgtcaagagagctctccaacctcatcatc
atgcgggggcctgcggccagcaccaggccactcaacctcagccagctcagcttccaccgg
gtctgccgggaggagatcacccagctgtcccacttgggccagggcacgaggaccaatgtg
tatgagggcctcctgcgtgtgaagggcagggactctgaggaggacaaggaggaaggcggg
gaccccctctcacccagtaggggcagcgggcaggagctccgagtggtgctcaaggtgctg
gaccccagtcaccatgacatcaccctggccttctacgagattgccagcctcatgagccag
gtctcccacgtgcacctggcctttgtgcacggcatctgtgtacatggttctgagagtgag
tgccccctgcccctgcttataggccagctcccacttatacccagtccctggcctgtcccc
cgacccctaatggcaccctgcctgacctacgagccagcccagcggccgtccttccgcatc
atcctgcgcgacctcactcggctgcagccccacaatcttgttgacgtttctgctgtgagc
ccggacttgccagcgtcagaccccacggttttccacaagcgctatttgaaaaagatccgg
gagctgggcgagggtcactttggcaaggtcagcttgtactgctatgacccgactaacgat
ggcactggtgagatggtagccgtaaagtccctgaaggcaggctgcggcccccagcttcgt
tcgggctggaagcgtgagatcgacattctgcgcaggctctatcacgaacacatcgtcaag
tacaagggttgctgcgaggacccaggcgagaagtcggtgcagctggtcatggagtacgtc
cccctgggtagcctccgagactacctgccccggcacagtgtggggctggcccagctactg
ctcttcgcccagcagatctgcgagggcatggcctacctgcacgcgcagcactacatccac
cgagacttggctgcccgcaacgtgctgctggacaacgacaggctggtcaagatcggggac
ttcggcctggccaaggctgtgcctgaaggccatgagtactaccgcgtgcgcgaggacggg
gacagccccgtgttctggtatgccccggagtgcctgaaggagtgtaagttctactatgca
tctgacgtctggtcctttggggtcaccctgtatgagttgctgacccgctgtgacttcagc
cagagcccccccttgaaattcatcgagctcctaggcctcacccagggacagatgacggtg
ctgaggctcactgagttgctggaacgaggggagaggctgccgcgccctgaggcatgtccc
tgtgagatctattacctcatgaagaactgctgggaggcagaggcctcattccgcccgacc
ttccagaacctcatccccatccttaagacagtccatgagaaataccaaggccaggccccc
tcagtgttcagtatgtgctga
DBGET
integrated database retrieval system
