KEGG   Loxodonta africana (African savanna elephant): 100673903
Entry
100673903         CDS       T04351                                 

Gene name
LYN
Definition
(RefSeq) tyrosine-protein kinase Lyn isoform X2
  KO
K05854  tyrosine-protein kinase Lyn [EC:2.7.10.2]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04062  Chemokine signaling pathway
lav04064  NF-kappa B signaling pathway
lav04611  Platelet activation
lav04662  B cell receptor signaling pathway
lav04664  Fc epsilon RI signaling pathway
lav04666  Fc gamma R-mediated phagocytosis
lav04730  Long-term depression
lav05167  Kaposi sarcoma-associated herpesvirus infection
lav05169  Epstein-Barr virus infection
lav05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    100673903 (LYN)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100673903 (LYN)
   04662 B cell receptor signaling pathway
    100673903 (LYN)
   04664 Fc epsilon RI signaling pathway
    100673903 (LYN)
   04666 Fc gamma R-mediated phagocytosis
    100673903 (LYN)
   04062 Chemokine signaling pathway
    100673903 (LYN)
  09156 Nervous system
   04730 Long-term depression
    100673903 (LYN)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    100673903 (LYN)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    100673903 (LYN)
   05169 Epstein-Barr virus infection
    100673903 (LYN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lav01001]
    100673903 (LYN)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lav04131]
    100673903 (LYN)
Enzymes [BR:lav01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     100673903 (LYN)
Protein kinases [BR:lav01001]
 Non-receptor tyrosine kinases
  SRC family
   100673903 (LYN)
Membrane trafficking [BR:lav04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    100673903 (LYN)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 SH3_3
Other DBs
NCBI-GeneID: 100673903
NCBI-ProteinID: XP_003420050
LinkDB
Position
Unknown
AA seq 491 aa
MGCIKSKRKDNLNDDGVDLKPQPVSESQLLPGQRFQAKDPEEQGDIVVALYPYDGIHPDD
LSFKKGEKMKVLEEHGEWWKAKSLSTKREGFIPSNYVAKVNTLETEEWFFKDITRKDAER
QLLAPGNSPGAFLIRESETLKGSYSLSVRDYDPVHGDVIKHYKIRSLDNGGYYISPRITF
PCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAWEIPRESIKLMKRLGAGQFGDV
WMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEY
MAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMC
KIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGK
IPYPGRTNADVMTALSQGYRMPQMENCPDELYEIMKLCWKEKAEERPTFDYLQSVLDDFY
TATEGQYQQQP
NT seq 1476 nt   +upstreamnt  +downstreamnt
atgggatgtataaaatcaaaaaggaaagacaatctgaatgacgatggagtagatctgaag
ccccaaccagtttcagaatctcagcttttgccaggacagagatttcaagctaaagatccg
gaggagcaaggagacattgtggtagccttgtacccctacgatggcattcacccagacgac
ttgtcgtttaagaaaggagagaaaatgaaagttctggaggaacatggagagtggtggaaa
gcgaaatccctttcaacaaagagagaaggcttcatccccagcaattacgtagccaaagtc
aacaccttagagacggaagagtggtttttcaaggatataaccaggaaggatgccgagagg
cagcttctggctcccggaaatagccctggagcctttctcatcagagagagtgagacgttg
aaaggaagctactctctgtctgtcagggattatgaccctgtacatggtgatgttattaag
cactacaaaattagaagtctggacaatgggggttattacatctcgccacgcatcactttc
ccctgtatcagtgacatgattaaacattatcaaaagcagtcggatggcttgtgcagaaga
ttggagaaggcctgcattagtcccaaaccacagaaaccatgggataaagatgcctgggag
attccacgggagtccatcaagttgatgaagaggctgggcgctggccagtttggagacgtc
tggatgggttactataataacagcactaaagtagctgtgaaaacgctgaagccgggcacc
atgtcagtgcaggccttcctggaggaagcgaacctcatgaagacactgcagcatgacaaa
ctggtgcgactctatgccgtggtcaccaaggaggagcccatctacatcatcacggagtac
atggccaaaggcagtttgctggatttcctgaagagcgatgaaggtggcaaagtcctgctt
ccaaagctaattgacttttctgctcagattgcggaaggaatggcgtatattgagaggaag
aactacatccaccgagacctgcgagcagccaatgtcctggtgtcggagtccctgatgtgt
aaaatcgccgacttcggcctcgcacgcgtcattgaggacaacgagtacactgcacgggaa
ggtgctaagttccctattaagtggacagctccagaagccatcaactttgggtgcttcacc
attaagtctgatgtgtggtcctttggaattctcctgtatgaaattgtcacctatgggaaa
attccctacccagggagaaccaatgccgacgtgatgaccgccctgtctcagggctacagg
atgccccaaatggagaactgccccgatgagctgtacgagatcatgaagttgtgctggaag
gagaaggctgaagagaggcccacgtttgattacttacagagcgtcctggatgacttctac
acagccacagaagggcagtaccagcagcaaccttag

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