Loxodonta africana (African savanna elephant): 100673992
Help
Entry
100673992 CDS
T04351
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase, brain isoform X2
KO
K13240
nitric-oxide synthase, brain [EC:
1.14.13.39
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00220
Arginine biosynthesis
lav00330
Arginine and proline metabolism
lav01100
Metabolic pathways
lav04020
Calcium signaling pathway
lav04081
Hormone signaling
lav04145
Phagosome
lav04371
Apelin signaling pathway
lav04713
Circadian entrainment
lav04730
Long-term depression
lav04926
Relaxin signaling pathway
lav04970
Salivary secretion
lav05010
Alzheimer disease
lav05014
Amyotrophic lateral sclerosis
lav05022
Pathways of neurodegeneration - multiple diseases
lav05410
Hypertrophic cardiomyopathy
lav05412
Arrhythmogenic right ventricular cardiomyopathy
lav05414
Dilated cardiomyopathy
lav05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100673992 (NOS1)
00330 Arginine and proline metabolism
100673992 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
100673992 (NOS1)
04020 Calcium signaling pathway
100673992 (NOS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
100673992 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
100673992 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
100673992 (NOS1)
09154 Digestive system
04970 Salivary secretion
100673992 (NOS1)
09156 Nervous system
04730 Long-term depression
100673992 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
100673992 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100673992 (NOS1)
05014 Amyotrophic lateral sclerosis
100673992 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
100673992 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100673992 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
100673992 (NOS1)
05414 Dilated cardiomyopathy
100673992 (NOS1)
05416 Viral myocarditis
100673992 (NOS1)
Enzymes [BR:
lav01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100673992 (NOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
PDZ
PDZ_6
PDZ_2
Motif
Other DBs
NCBI-GeneID:
100673992
NCBI-ProteinID:
XP_010597242
UniProt:
G3TS49
LinkDB
All DBs
Position
Unknown
AA seq
1434 aa
AA seq
DB search
MEEHMFSVQQIQPNVISVRLFKRKVGGLGFLVKERVTKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGRPLVDLTYDSALEVLRGVASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTRPLGPATKAVDLSHQPSTSKEKPLAVDGSLGPGNRPQHAQDNRQEAGSLSHANGLAP
RPMSEDSAKKSASTGLQGGGENNDLLKEIEPVLNLLTSGSKGINGGRPAKVEMKDAEIQV
DRDLDGKPHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPASEKQSPTKNGSPS
KCPRFLKVKNWETDVVLTDTLHLKSTLESGCSEHICMGSIMLPSQQIRKPEEVRTKEQLF
PLAKEFIDQYYSSIKRFGSKAHMDRLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRC
VGRIQWSKLQVFDARDCTTAHGMYNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVW
NSQLIRYAGYKQPDGSILGDPANVEFTEICIQQGWKPPRGRFDVLPLMLQANGNDPELFQ
IPPELVLEVPIRHPKLEWFKDLGLKWYGVPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPCFEYQPDPWNTHV
WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKSLCE
IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSIQ
EERKSYKVRFNSVSSYSDSRKSLGEGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAF
GHAVDTLLEELGGERILKMGEGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANN
SLISNDRSWKRNKFRLTYVAEAPELTQGLSSVHKKRVSAARLLSRQNLQSPKSSRSTIFV
RLHTNGNQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPTNQLVKVELLEERNTALGV
ISNWTDEHRLPPCTVFQAFKYYLDITTPPTPLQLQLFASLATSEKEKQRLLVLSKGLQEY
EEWKWGKNPTIVEVLEEFSSIQMPTTLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIV
SYRTQDGEGPIHHGVCSSWLNQIQADEVVPCFVRGAPSFRLPRNPQVPCILVGPGTGIAP
FRSFWQQRQFDIQHKGMSPCPMVLVFGCRQSKIDHIYKEETLQAKNKGVFRELYTAYSRE
PEKPKKYVQDILQEQLAEPVYQALKEQGGHIYVCGDVTMAADVLKAIQRIVTQQGKLSVE
DAGVFVSRLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
NT seq
4305 nt
NT seq
+upstream
nt +downstream
nt
atggaggaacatatgttcagtgtccagcaaatccaacccaacgtcatttctgtccgcctc
ttcaagcgcaaagtgggaggcctgggcttcctggtgaaggagcgggtcaccaagccaccc
gtgattatttccgacctgattcgagggggtgctgcagagcagagcggcctcatccaggct
ggagacatcatcctggccgtcaatgggcggcccttggtcgacctgacctatgacagcgcc
ctggaggtgctcaggggcgttgcctctgagacccatgtggtcctcattctgaggggccct
gagggcttcaccacacacctggagaccaccttcactggggatggaacccccaagaccatc
cgggtgacacggcccctgggtcctgccaccaaagctgtcgatctgtcccaccagccatca
accagcaaagagaagccactggcggtggatgggtccctggggcctggaaaccggcctcag
catgcccaagacaacaggcaggaagctggctcactctcgcacgccaatggcctagccccc
aggcccatgagtgaggactctgccaagaaaagtgccagtactggtctccaaggaggtggg
gagaacaatgacctgctcaaggagatagagcctgtgctcaacctcctcaccagtgggagc
aaagggatcaatggagggagacctgccaaggtggagatgaaagacgcagaaatccaggtg
gacagagacttggatggaaaaccacacaagccactgccccttggcgtggagaacgaccgc
gtcttcaacgacctgtgggggaaaggcaatgtgcctgtcgtcctcaacaacccatattca
gagaaggagcagcccccggcctcagaaaaacagtcccccacaaagaatggcagcccctcc
aagtgcccccgcttcctcaaggtcaagaactgggagactgacgtggttctcactgacacc
ctccaccttaagagcaccttggaatcgggatgctctgagcacatctgtatgggctctatc
atgctcccttctcagcaaatacgaaagcccgaagaagtccgcacgaaagaacagctcttc
cctctcgccaaagagtttattgatcagtactactcgtcaattaaaagatttgggtccaaa
gcccacatggacaggctggaagaggtgaacaaagagattgagaccaccagcacctaccaa
ctcaaggacacggagctcatctacggggccaagcacgcctggcggaatgcctcccgctgc
gtcggcaggatccagtggtccaagctgcaggtatttgatgcccgagactgcaccacggct
cacgggatgtacaactacatctgcaaccacatcaagtacgccaccaacaaagggaacctc
aggtctgccatcaccatatttccccagaggacagacggcaagcatgacttcagggtctgg
aactcccagctcatccgctatgcaggctacaagcagcctgatggctccatcctgggggac
ccagccaacgtggagttcacagagatctgcatacagcagggctggaagcccccccgaggc
cgcttcgacgtcctgccactcatgctgcaggccaacggcaacgaccccgagctcttccag
attcctccagagctggtgctggaggtgcccatcaggcaccccaagctcgagtggttcaag
gacctggggctgaagtggtatggtgtccctgctgtgtccaacatgctcctggagatcggt
ggcctggagttcagtgcctgtcccttcagcggctggtacatgggcacagagatcggcgtc
cgggactactgtgacaattcgcgctacaacattctggaggaagtggccaagaagatgaac
ttggacatgaggaagacatcttccctgtggaaggaccaggctctggtggagatcaacatt
gccgtcctctacagcttccagagtgacaaagtgaccatcgttgaccatcactctgccacg
gagtccttcattaagcacatggagaatgagtaccgctgccgggggggctgcccagctgac
tgggtgtggatcgtgccccccatgtctggcagcatcacccctgtcttccaccaggagatg
ctcaactaccggctcaccccctgcttcgagtaccagcctgatccttggaacacccatgtc
tggaaaggcaccaatgggacccccacaaagcggcgagccattggcttcaagaagctggca
gaagctgtcaagttctccgctaaactgatggggcaggcaatggctaagagagtcaaagcc
accatcctctatgccaccgagactggcaaatcgcaggcctatgctaaatccttgtgtgag
atcttcaaacacgcctttgatgccaaggtgatgtccatggaagaatatgacatcgtgcac
ctggagcacgaaactctggtcctggtagttaccagcacctttggcaatggagaccccccc
gagaatggggagaaattcggctgtgctttgatggaaatgaggcatcccaactctatacag
gaggagaggaagagctacaaggttcgattcaatagcgtctcctcctattcagactcccgc
aaatcactgggcgaagggcctgacctcagagacaactttgagagtgctggacccctagca
aatgtgaggttctcagtgtttggccttggctcacgggcataccctcacttctgcgccttt
ggacatgctgtggacaccctcctggaagagctaggaggggagaggatcctgaagatggga
gagggggatgaactctgtgggcaggaagaggctttcaggacctgggccaagaaggtcttc
aaggcagcctgtgatgtgttctgcgtgggggatgatgtcaacatcgagaaggccaacaac
tccctcatcagcaatgaccgcagctggaagaggaacaaattccgcctcacctatgtggct
gaggctccagaacttacacaaggtctatccagtgttcacaaaaagcgggtctcagctgct
cgactcctgagccgtcaaaaccttcagagtcctaaatccagccgatccaccattttcgtg
cggctccacacgaatgggaatcaggagctgcagtaccagcctggagaccacctgggtgtc
ttccccggcaaccacgaggacctggtgaatgccctgattgagcggctggaggatgcaccc
cctaccaaccagctggtaaaggtggagctgctggaggagcggaacacagctttgggtgtc
atcagtaactggacagacgagcaccgcctcccaccctgcaccgtattccaggccttcaag
tactacctggacatcaccacgccaccaacgcccttgcagctgcagctgtttgcctccctg
gccaccagcgagaaggagaagcagcgtctgctggtcctcagcaagggtttgcaggagtat
gaggaatggaagtggggcaagaaccccaccatcgtggaggtactggaagagttctcgtcc
atccagatgcccaccactctgctcctgacccagctatctctgctgcagccacgctactac
tccatcagctcctccccagacatgtacccggatgaggtgcacctcactgtggccatcgtc
tcctaccgtacccaagatggagaaggaccaattcatcacggcgtgtgctcctcctggctc
aaccagatacaggctgatgaagtggtcccctgttttgtgagaggagcacctagcttccgc
cttccccgaaatccccaagtgccctgcatcctggttggcccggggactggcatcgcccct
ttccgaagcttctggcagcagcgccaatttgatatccaacacaaaggaatgagtccctgc
cccatggtcctggtctttgggtgccggcaatccaagatagaccacatctacaaggaagaa
accctacaggccaagaacaagggggtcttcagagagctgtacacggcctactcccgggaa
ccagagaaaccaaagaagtacgtacaggacatccttcaagagcaattggctgagcccgtg
taccaagccctgaaggagcaagggggccacatttatgtctgcggggacgtcaccatggcc
gctgatgtcctcaaagccatccagcgcatcgtgacccagcaggggaaactctcagtggag
gacgccggcgtgttcgtcagtagactgagggatgacaaccggtaccatgaggatattttt
ggggtcaccctgcggacgtatgaagtgaccaaccgccttagatctgagtccattgccttc
attgaagagagcaaaaaagatacagacgaggttttcagctcctaa
DBGET
integrated database retrieval system
