Loxodonta africana (African savanna elephant): 100675105
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Entry
100675105 CDS
T04351
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase-3 beta isoform X2
KO
K03083
glycogen synthase kinase 3 beta [EC:
2.7.11.26
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav01521
EGFR tyrosine kinase inhibitor resistance
lav04012
ErbB signaling pathway
lav04062
Chemokine signaling pathway
lav04110
Cell cycle
lav04150
mTOR signaling pathway
lav04151
PI3K-Akt signaling pathway
lav04310
Wnt signaling pathway
lav04340
Hedgehog signaling pathway
lav04360
Axon guidance
lav04390
Hippo signaling pathway
lav04510
Focal adhesion
lav04550
Signaling pathways regulating pluripotency of stem cells
lav04657
IL-17 signaling pathway
lav04660
T cell receptor signaling pathway
lav04662
B cell receptor signaling pathway
lav04722
Neurotrophin signaling pathway
lav04728
Dopaminergic synapse
lav04910
Insulin signaling pathway
lav04916
Melanogenesis
lav04917
Prolactin signaling pathway
lav04919
Thyroid hormone signaling pathway
lav04931
Insulin resistance
lav04932
Non-alcoholic fatty liver disease
lav04934
Cushing syndrome
lav04935
Growth hormone synthesis, secretion and action
lav04936
Alcoholic liver disease
lav05010
Alzheimer disease
lav05020
Prion disease
lav05022
Pathways of neurodegeneration - multiple diseases
lav05135
Yersinia infection
lav05160
Hepatitis C
lav05162
Measles
lav05163
Human cytomegalovirus infection
lav05165
Human papillomavirus infection
lav05167
Kaposi sarcoma-associated herpesvirus infection
lav05200
Pathways in cancer
lav05210
Colorectal cancer
lav05213
Endometrial cancer
lav05215
Prostate cancer
lav05217
Basal cell carcinoma
lav05224
Breast cancer
lav05225
Hepatocellular carcinoma
lav05226
Gastric cancer
lav05415
Diabetic cardiomyopathy
lav05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100675105 (GSK3B)
04310 Wnt signaling pathway
100675105 (GSK3B)
04340 Hedgehog signaling pathway
100675105 (GSK3B)
04390 Hippo signaling pathway
100675105 (GSK3B)
04151 PI3K-Akt signaling pathway
100675105 (GSK3B)
04150 mTOR signaling pathway
100675105 (GSK3B)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100675105 (GSK3B)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100675105 (GSK3B)
04550 Signaling pathways regulating pluripotency of stem cells
100675105 (GSK3B)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
100675105 (GSK3B)
04657 IL-17 signaling pathway
100675105 (GSK3B)
04662 B cell receptor signaling pathway
100675105 (GSK3B)
04062 Chemokine signaling pathway
100675105 (GSK3B)
09152 Endocrine system
04910 Insulin signaling pathway
100675105 (GSK3B)
04917 Prolactin signaling pathway
100675105 (GSK3B)
04935 Growth hormone synthesis, secretion and action
100675105 (GSK3B)
04919 Thyroid hormone signaling pathway
100675105 (GSK3B)
04916 Melanogenesis
100675105 (GSK3B)
09156 Nervous system
04728 Dopaminergic synapse
100675105 (GSK3B)
04722 Neurotrophin signaling pathway
100675105 (GSK3B)
09158 Development and regeneration
04360 Axon guidance
100675105 (GSK3B)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100675105 (GSK3B)
09162 Cancer: specific types
05210 Colorectal cancer
100675105 (GSK3B)
05225 Hepatocellular carcinoma
100675105 (GSK3B)
05226 Gastric cancer
100675105 (GSK3B)
05217 Basal cell carcinoma
100675105 (GSK3B)
05215 Prostate cancer
100675105 (GSK3B)
05213 Endometrial cancer
100675105 (GSK3B)
05224 Breast cancer
100675105 (GSK3B)
09172 Infectious disease: viral
05160 Hepatitis C
100675105 (GSK3B)
05162 Measles
100675105 (GSK3B)
05163 Human cytomegalovirus infection
100675105 (GSK3B)
05167 Kaposi sarcoma-associated herpesvirus infection
100675105 (GSK3B)
05165 Human papillomavirus infection
100675105 (GSK3B)
09171 Infectious disease: bacterial
05135 Yersinia infection
100675105 (GSK3B)
09164 Neurodegenerative disease
05010 Alzheimer disease
100675105 (GSK3B)
05020 Prion disease
100675105 (GSK3B)
05022 Pathways of neurodegeneration - multiple diseases
100675105 (GSK3B)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100675105 (GSK3B)
05415 Diabetic cardiomyopathy
100675105 (GSK3B)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100675105 (GSK3B)
04932 Non-alcoholic fatty liver disease
100675105 (GSK3B)
04931 Insulin resistance
100675105 (GSK3B)
04934 Cushing syndrome
100675105 (GSK3B)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100675105 (GSK3B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100675105 (GSK3B)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
lav03036
]
100675105 (GSK3B)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.26 tau-protein kinase
100675105 (GSK3B)
Protein kinases [BR:
lav01001
]
Serine/threonine kinases: CMGC group
GSK family [OT]
100675105 (GSK3B)
Chromosome and associated proteins [BR:
lav03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100675105 (GSK3B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Kinase-like
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
100675105
NCBI-ProteinID:
XP_003413025
LinkDB
All DBs
Position
Unknown
AA seq
420 aa
AA seq
DB search
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALF
NFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANAGDRGQTNNAASASASNST
NT seq
1263 nt
NT seq
+upstream
nt +downstream
nt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccagtgcagcagcct
tcagcttttggcagcatgaaagttagcagagacaaggatggcagtaaggtgaccacagtg
gtggcaactcctgggcagggtccagacaggccgcaggaagtcagctatacagacactaaa
gtgattggaaatgggtcgtttggtgtggtatatcaagccaaactttgtgattcaggagaa
ctggttgccatcaagaaagtattgcaggacaaaagatttaagaaccgagagctccagatc
atgagaaagctagaccactgtaacatagtccgattgcgttatttcttctactcaagcggt
gagaagaaagatgaggtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgctccctgtgatctatgtcaagttg
tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatctgccaccgg
gatattaaaccacaaaacctcttgttggatcctgatacagctgtcttaaaactctgtgac
tttggaagcgcaaagcagctggtccgaggagagcccaatgtttcctatatctgttctcgg
tactacagggcaccggagttgatctttggagccactgattacacctccagcatagatgtg
tggtctgcaggctgtgtgttggctgaactgttgctaggacaaccaatatttccaggggac
agtggtgtggatcagttggtggaaataatcaaggtcctgggaacaccaacaagggagcaa
attagagaaatgaatccaaattacacagaattcaaattccctcaaattaaggcacatcct
tggacaaaggtcttccgaccccgaaccccaccggaggccattgcactgtgtagccgtctg
ctggagtatacaccgactgcccgactgacgccactggaagcttgtgcacattcatttttt
gatgaattacgggacccaaatgtcaaactaccaaatgggcgagacacacctgcactcttc
aacttcaccactcaagagctgtccagtaatccacctctggctaccatccttattcctcct
catgctcggattcaagcagctgcttcaacccctacaaatgccacagcagcctcagacgct
aacgctggagaccgtggacagaccaataacgccgcttccgcatcggcttccaactccacc
tga
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