Loxodonta africana (African savanna elephant): 100676113
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Entry
100676113 CDS
T04351
Gene name
PDE11A
Definition
(RefSeq) dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
KO
K13298
dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:
3.1.4.17
3.1.4.35
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00230
Purine metabolism
lav01100
Metabolic pathways
lav04934
Cushing syndrome
lav05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100676113 (PDE11A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100676113 (PDE11A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100676113 (PDE11A)
Enzymes [BR:
lav01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100676113 (PDE11A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
100676113 (PDE11A)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
HD
Motif
Other DBs
NCBI-GeneID:
100676113
NCBI-ProteinID:
XP_003406019
LinkDB
All DBs
Position
Unknown
AA seq
933 aa
AA seq
DB search
MTTPGLDFGEVESFLDRHPELFEDYLLRKGKQEMVEKWLQRHSHGQGALGPRPTLAGTSS
LAHGGGRRSSIVGGGTGPNGSANSQPTPGGGDCSGVPLSPSWASGSRGDGSLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKSLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIQSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELMSPKCSADTENSFKESMEKSSYSDWLINNSVAELVA
STGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSG
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAV
NRSKWEELHQKRLLASAASPSPASLTVAAEDRK
NT seq
2802 nt
NT seq
+upstream
nt +downstream
nt
atgacaacccctggcctggacttcggggaggtggaaagtttcctggacaggcacccagag
ttgttcgaagattacctgttgcggaaggggaagcaggagatggtggagaagtggctgcag
aggcacagtcatggtcagggggctttaggcccaaggcccactctggctggcaccagcagc
ttggctcatggcggtggcagaagaagcagcatcgttggtggtggcactggaccaaatggc
tctgccaacagccagcctactcctggtggtggggactgtagtggggttcctttgagtccc
agctgggccagtggcagccgaggtgatgggagcctgcagcgaagagcttctcagaaagag
ctaaggaagagttttgctcgctccaaggccatccatgtgaacaggacctacgatgaacag
gtgacctcccgggcccaagagcccctgagcagtgtgcggcggagggcgctgctccggaag
gcgagctctctgccccccaccacagcccacattctcagtgccctactggaatcgagggtg
aatctgcctcagtacccccctacagccatcgattacaagtgccatctcaaaaagcacaat
gagcgtcagttcttcctggaactggtcaaggatatctccaatgaccttgacctcaccagc
ctgagctacaagatcctcatctttgtctgcctcatggtagatgctgaccgctgctctctc
ttcttggtggaaggggcagctgctggcaagaagagcttggtctccaaattctttgatgtg
catgcaggaaccccactgctgccgtgcagcagcacagagaactcaaatgaggtgcaggtc
ccctggggcaaaggcatcattggctatgtcggggagcatggagaaacggtcaacattcct
gatgcctaccaggatcgaagattcaatgatgaaattgacaagctaactggatacaagaca
aaatcattactgtgcatgcctatccaaagcagtgatggcgagattatcggtgtggcccaa
gcaataaataagattcctgaaggtgctccatttactgaagatgacgaaaaagttatgcag
atgtaccttcctttttgtggaattgccatatccaatgctcaactctttgctgcctcaagg
aaagaatatgaaagaagcagggctttactagaggtggttaatgatctctttgaagaacag
actgacctggagaaaatcgtcaagaaaataatgcatcgggcccagactctgttgaaatgt
gaacgctgttctgttttactcttagaggacattgagtcaccagtggtgaagtttaccaaa
tcctttgaattgatgtccccaaaatgcagcgctgatactgagaacagtttcaaagaaagc
atggagaaatcatcatactcagactggctaataaataacagtgtggctgagctggttgct
tctacgggcctcccagtgaacatcagtgatgcctaccaggatcctcgctttgatgctgag
gctgaccagatatccggttttcacataagatctgttctctgcgttcctatttggaatagc
aaccaccaaataattggggtggctcaagtgttaaatagattggatgggaaaccttttgat
gatgcagatcagcgactttttgaggcttttgtcatcttttgtggccttggcatcaacaac
acaattatgtatgatcaagtgaagaagtcctgggctaagcagtctgtggctcttgatgtg
ctgtcctaccatgcgacatgttcaaaagctgaagttgacaagtttaaggcagccaacatc
cctctggtgtcagaacttgccatcgatgacatacattttgatgacttttctctcgacgtt
gacgccatgatcacggctgctctccggatgttcatggagctggggatggtacagaaattt
aaaatcgactatgagactctgtgtaggtggcttttgacagtgaggaaaaactatcgcatg
gttctgtaccacaactggagacatgccttcaacgtgtgccaactgatgttcgcgatgtta
actactgcagggtttcaagagattctgaccgaggtggaaattttagctgtgattgtgggc
tgcctgtgtcacgacctcgaccacaggggaaccaacaatgccttccaagctaagagcggc
tctgccctggcccagctctatggaacctctgccaccctagagcatcaccattttaaccat
gcagtgatgatccttcagagtgagggtcacaacatctttgctaatttgtcctccaaggaa
tatagcgaccttatgcagcttttgaagcagtcaatcttggcaacagacctcacgctgtac
tttgagaggagaaccgaattctttgaacttgtcagtaaaggtgaatatgattggaacatc
aaaaaccatcgtgatatatttcgatcaatgttaatgacagcctgtgaccttggagccgtg
accaaaccgtgggagatctccagacaggtggctgaacttgtaaccagtgagttctttgaa
caaggagatcgggagagatcagaactcaaactcactccttcagctatttttgatcggaac
cggaaagatgaactgcctcgattgcaattggaatggattgatagcatctgcatgcctttg
tatcaggcattggtgaaggtcaatgcgaaactgaagcccatgctggattcggtggctgtg
aacagaagtaagtgggaagagctgcaccagaaaaggctgctggcttcggccgcctcgccc
tctcctgccagcctcacggtggctgcagaggacagaaagtaa
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