Lemur catta (Ring-tailed lemur): 123640770
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Entry
123640770 CDS
T08326
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat01522
Endocrine resistance
lcat04010
MAPK signaling pathway
lcat04015
Rap1 signaling pathway
lcat04068
FoxO signaling pathway
lcat04071
Sphingolipid signaling pathway
lcat04114
Oocyte meiosis
lcat04148
Efferocytosis
lcat04218
Cellular senescence
lcat04261
Adrenergic signaling in cardiomyocytes
lcat04370
VEGF signaling pathway
lcat04380
Osteoclast differentiation
lcat04550
Signaling pathways regulating pluripotency of stem cells
lcat04611
Platelet activation
lcat04613
Neutrophil extracellular trap formation
lcat04620
Toll-like receptor signaling pathway
lcat04621
NOD-like receptor signaling pathway
lcat04622
RIG-I-like receptor signaling pathway
lcat04625
C-type lectin receptor signaling pathway
lcat04657
IL-17 signaling pathway
lcat04658
Th1 and Th2 cell differentiation
lcat04659
Th17 cell differentiation
lcat04660
T cell receptor signaling pathway
lcat04664
Fc epsilon RI signaling pathway
lcat04668
TNF signaling pathway
lcat04670
Leukocyte transendothelial migration
lcat04714
Thermogenesis
lcat04722
Neurotrophin signaling pathway
lcat04723
Retrograde endocannabinoid signaling
lcat04728
Dopaminergic synapse
lcat04750
Inflammatory mediator regulation of TRP channels
lcat04912
GnRH signaling pathway
lcat04914
Progesterone-mediated oocyte maturation
lcat04917
Prolactin signaling pathway
lcat04926
Relaxin signaling pathway
lcat04932
Non-alcoholic fatty liver disease
lcat04933
AGE-RAGE signaling pathway in diabetic complications
lcat04935
Growth hormone synthesis, secretion and action
lcat04936
Alcoholic liver disease
lcat05014
Amyotrophic lateral sclerosis
lcat05020
Prion disease
lcat05022
Pathways of neurodegeneration - multiple diseases
lcat05132
Salmonella infection
lcat05133
Pertussis
lcat05135
Yersinia infection
lcat05140
Leishmaniasis
lcat05142
Chagas disease
lcat05145
Toxoplasmosis
lcat05152
Tuberculosis
lcat05161
Hepatitis B
lcat05163
Human cytomegalovirus infection
lcat05167
Kaposi sarcoma-associated herpesvirus infection
lcat05169
Epstein-Barr virus infection
lcat05170
Human immunodeficiency virus 1 infection
lcat05171
Coronavirus disease - COVID-19
lcat05205
Proteoglycans in cancer
lcat05208
Chemical carcinogenesis - reactive oxygen species
lcat05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
lcat05415
Diabetic cardiomyopathy
lcat05417
Lipid and atherosclerosis
lcat05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123640770 (MAPK12)
04015 Rap1 signaling pathway
123640770 (MAPK12)
04370 VEGF signaling pathway
123640770 (MAPK12)
04668 TNF signaling pathway
123640770 (MAPK12)
04068 FoxO signaling pathway
123640770 (MAPK12)
04071 Sphingolipid signaling pathway
123640770 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
123640770 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
123640770 (MAPK12)
04218 Cellular senescence
123640770 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
123640770 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123640770 (MAPK12)
04613 Neutrophil extracellular trap formation
123640770 (MAPK12)
04620 Toll-like receptor signaling pathway
123640770 (MAPK12)
04621 NOD-like receptor signaling pathway
123640770 (MAPK12)
04622 RIG-I-like receptor signaling pathway
123640770 (MAPK12)
04625 C-type lectin receptor signaling pathway
123640770 (MAPK12)
04660 T cell receptor signaling pathway
123640770 (MAPK12)
04658 Th1 and Th2 cell differentiation
123640770 (MAPK12)
04659 Th17 cell differentiation
123640770 (MAPK12)
04657 IL-17 signaling pathway
123640770 (MAPK12)
04664 Fc epsilon RI signaling pathway
123640770 (MAPK12)
04670 Leukocyte transendothelial migration
123640770 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
123640770 (MAPK12)
04914 Progesterone-mediated oocyte maturation
123640770 (MAPK12)
04917 Prolactin signaling pathway
123640770 (MAPK12)
04926 Relaxin signaling pathway
123640770 (MAPK12)
04935 Growth hormone synthesis, secretion and action
123640770 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
123640770 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
123640770 (MAPK12)
04723 Retrograde endocannabinoid signaling
123640770 (MAPK12)
04722 Neurotrophin signaling pathway
123640770 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
123640770 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
123640770 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
123640770 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
123640770 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
123640770 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123640770 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
123640770 (MAPK12)
05161 Hepatitis B
123640770 (MAPK12)
05171 Coronavirus disease - COVID-19
123640770 (MAPK12)
05163 Human cytomegalovirus infection
123640770 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
123640770 (MAPK12)
05169 Epstein-Barr virus infection
123640770 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
123640770 (MAPK12)
05135 Yersinia infection
123640770 (MAPK12)
05133 Pertussis
123640770 (MAPK12)
05152 Tuberculosis
123640770 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
123640770 (MAPK12)
05140 Leishmaniasis
123640770 (MAPK12)
05142 Chagas disease
123640770 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
123640770 (MAPK12)
05020 Prion disease
123640770 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
123640770 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123640770 (MAPK12)
05418 Fluid shear stress and atherosclerosis
123640770 (MAPK12)
05415 Diabetic cardiomyopathy
123640770 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
123640770 (MAPK12)
04932 Non-alcoholic fatty liver disease
123640770 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
123640770 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
123640770 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lcat01001
]
123640770 (MAPK12)
Enzymes [BR:
lcat01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
123640770 (MAPK12)
Protein kinases [BR:
lcat01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
123640770 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Kdo
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
123640770
NCBI-ProteinID:
XP_045411320
LinkDB
All DBs
Position
6:690464..698274
Genome browser
AA seq
367 aa
AA seq
DB search
MSSPPPARSGFYRQEVTKTAWDVRAVYRDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGTDHLDQLKEIMK
VTGTPSPEFVQRLQSADAKNYMKGLPELEKKDFASILTNASPLAVSLLEKMLVLDAEQRV
TAAEALAHPYFESLHDTEEAPAAQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRHLGTR
VSKETAL
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
atgagctctccgccgcctgcccgcagtggcttttaccgccaggaggtgaccaagaccgcc
tgggacgtgcgcgccgtgtaccgggacctgcagcccgtgggctcgggcgcctacggcgcg
gtgtgctcggccgtggacagccgcacgggcgccaaggtggccatcaagaagctgtaccgg
cccttccagtcagagctgtttgccaagcgcgcctaccgcgagctgcgcctcctcaaacac
atgcgccacgagaacgtgatcgggctgctggacgtgttcacgcctgacgagaccctggat
gacttcacagacttttacctggtgatgccgttcatggggaccgacctgggcaagctcatg
aagcacgagaagctgagtgaggaccggatccagttcctggtgtaccagatgctgaagggg
ctcaagtatatccacgctgctggcatcatccacagggacctgaagccgggcaacctagcg
gtgaatgaggactgtgagcttaagatcctggactttggcctggccaggcaggcagacagt
gagatgaccggatacgtggtgacgcggtggtaccgggcacccgaggtcatcttgaattgg
atgcgctacacgcagactgtggacatctggtccgtgggttgcatcatggctgagatgatt
acggggaagatactgttcaagggcaccgaccacctggaccagctgaaggagatcatgaag
gtgaccggcacgccgtcgcccgagtttgtgcagaggctgcagagtgcggatgcgaagaac
tacatgaagggcctccctgagctggagaagaaggactttgcctccatcctgaccaacgcc
agccccctggccgtgagcctcctggagaagatgctggtgctggatgcggagcagcgggtg
acggcggccgaggccctggcccacccctacttcgagtccctgcacgacacggaagaggcg
cctgcggcccagaagtacgacgactcctttgacgacgtggaccgcacgctggacgagtgg
aagcgtgtcacatacaaagaggtgctcagcttcaagccgcccaggcacctggggaccagg
gtttccaaggagacggctctgtga
DBGET
integrated database retrieval system