Labrys sp. KNU-23: FZC33_10500
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Entry
FZC33_10500 CDS
T06193
Name
(GenBank) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
lne
Labrys sp. KNU-23
Pathway
lne00280
Valine, leucine and isoleucine degradation
lne00640
Propanoate metabolism
lne00785
Lipoic acid metabolism
lne01100
Metabolic pathways
lne01110
Biosynthesis of secondary metabolites
lne01210
2-Oxocarboxylic acid metabolism
Module
lne_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lne00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
FZC33_10500
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
FZC33_10500
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FZC33_10500
Enzymes [BR:
lne01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
FZC33_10500
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
QEN86732
UniProt:
A0A5C1WE31
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Position
1:complement(187454..188728)
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AA seq
424 aa
AA seq
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MTKKTTLSLHIPEARFRPGDTPDFSYLNLPGAGEAQRPPVTAVASETRDLAFGMVRVLDD
AGNAVGPWDPKLDADTLRKALRAMMLTRYFDDQMFKAQRQGKTSFYMKCTGEEAVAVGQA
LALEAGDMCFPTYRQQGLLVARNWPLTDMMSQIYSNGQDRLKGRQLPVLYSAKDAGFFSI
SGNLATQVPQAVGWAMASAYKRDRRIAAAWIGDGSSAEGDFHHGMVFASVYHAPVLINLV
NNQWAISSSQGVAGGEEATFASRAIGFGMPGIRVDGNDLLAVYAVTRWAAERARSNHGPT
LIELFTYRVAAHSTSDDPGRYRPGDEEKYWPFGDPVERLKRHLVGLGEWNEERHQALAKE
LQAEVKAANVEAQRHGILSDGPHHGTDTMFEDVFKEMPWHLQEQLAELNRFEATKEAGHK
KEGE
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgaccaagaagaccacgctcagcctgcacataccggaagcacgcttccggccgggcgat
acgcccgatttcagctatctcaacctgccgggggcgggcgaggcccagcgcccgcccgtg
accgccgtcgcctccgaaacccgtgacctcgccttcggcatggtgcgggtgctcgacgac
gcgggcaatgcggtcggcccctgggaccccaagctcgatgccgacacattgcgcaaggcc
ctgcgcgccatgatgctgacgcgctatttcgacgaccagatgttcaaggcgcagcgccag
ggcaagacctccttctacatgaaatgcaccggcgaagaggcggtggctgtcggccaggcg
ctggctctggaagccggcgacatgtgcttcccgacctatcgccagcagggcctcctggtg
gcgcgcaactggccgctgaccgacatgatgtcccagatctattccaacgggcaggatcgc
ttgaaagggcggcaattgccggtgctctattcggccaaggatgccggattcttctccatc
tccggcaatctcgccacccaggtgccgcaggccgtcggctgggccatggcctcggcctat
aagcgcgaccggcgcattgctgcggcctggatcggtgatggctcctccgccgagggcgat
ttccatcacggcatggtgttcgcctccgtctatcacgcgccggtgctgatcaatctcgtc
aacaatcaatgggcgatctcgtccagccagggtgtcgctggcggcgaggaggcgaccttc
gcctcgcgcgccatcggtttcggcatgccgggcatccgggtcgacggcaacgatctgctc
gccgtctatgccgtgacacgctgggccgccgagcgcgcccgttccaatcatggcccgacc
ctgatcgagcttttcacttatcgcgtcgccgcccactccaccagcgacgatcccggccgc
tatcgccccggggatgaagagaaatactggcccttcggcgatccggtggagcgcctgaaa
cgccatctcgtcggcttgggcgaatggaacgaggagcgccatcaggcacttgccaaggaa
ttgcaggccgaggtcaaggccgccaatgtcgaagcccagcgccacggtattctcagcgac
gggccccaccatggcaccgacaccatgttcgaggacgtgttcaaggagatgccctggcat
ctccaggaacaactggccgagctcaaccgcttcgaggccaccaaggaagccggtcacaag
aaggagggcgaataa
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