Lactiplantibacillus plantarum WCFS1: lp_0518
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Entry
lp_0518 CDS
T00115
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lpl
Lactiplantibacillus plantarum WCFS1
Pathway
lpl00300
Lysine biosynthesis
lpl00550
Peptidoglycan biosynthesis
lpl01100
Metabolic pathways
lpl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lpl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
lp_0518 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
lp_0518 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
lp_0518 (murF)
Enzymes [BR:
lpl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
lp_0518 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
DUF3323
Motif
Other DBs
NCBI-ProteinID:
CCC78010
UniProt:
F9UKZ5
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All DBs
Position
463650..465038
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AA seq
462 aa
AA seq
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MKMQVAEIAKAVQAVNAEQAWPDVNVTGVAFDSRKLQAGDLFIPLMGANDGHQYIQSAIE
HGAVATLWASDHADDVPEDLPVIMVADTLTALQQLGQYYLQKINPKVVAVTGSNGKTTTK
DMIASVLSTQFNVTKTHANFNNQIGVPVTLLSMEPNTEVVVVEMGMDHFGELDFLSRLVQ
PDVAVITMIGEAHIEFFGTRDRIADAKMEIVHGLKEDGTFIFNGDEPLLQERAKEVSQHQ
RTFGLDDTNTLAGSDITTSRAQTQFKTSLWPDNTYTIPMMGAYNVNNALAALLVADTFHI
RPAAAQQAIASFVPTENRTEWLTGYRGEAILSDVYNSNPTAARRVLAAFAAVPTKGQRIA
VLGDMLELGDQSDALHMSLASELDPATIASVYLNGEHMRALAEVLQEKYPAGAVHYYQTD
QQPQLIADLTATVSADDQVLLKGSHGIHLEKVLTALEAAPEK
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgaagatgcaagttgccgaaattgctaaggccgttcaagcggtcaatgccgaacaggcg
tggcccgatgttaatgtaacgggtgtggcgtttgatagccgaaagctccaagcaggggat
ctatttattccgctgatgggcgctaatgatggtcatcaatatattcaaagtgcaatcgag
cacggggccgttgctaccttatgggccagcgaccatgccgacgacgttccagaagactta
cctgtcattatggttgctgatacattgacggcactacagcagctggggcaatactattta
caaaaaattaatccgaaagtcgtggctgttacgggtagtaatggtaaaacaacgacgaag
gatatgattgcgagtgttttgagcactcagtttaacgtgacaaagacgcacgccaacttt
aataatcagattggtgtgccagtgacgttactcagtatggaaccgaatacagaagtggtc
gtcgttgaaatggggatggaccattttggcgagttggatttcttgagccgtctcgttcaa
ccagacgttgcggtgattaccatgattggggaagcccacattgagttctttggtacacgg
gatcgaattgctgatgccaaaatggaaattgtccacggcttaaaagaagatggcacgttc
atttttaatggtgatgaaccactgctacaagaacgtgctaaggaagtcagtcagcatcaa
cggacgtttgggttggatgatacgaacaccttagcaggcagtgatatcacgactagtcgg
gctcaaacgcaatttaagacgagtctgtggccggacaacacgtacacaattccgatgatg
ggtgcgtacaatgtcaataatgcattggcggcactcttggtagctgatacttttcacatt
cgaccagccgctgcgcaacaagcaatcgccagttttgtgccgacggagaaccggacggaa
tggttaactggttaccgtggagaagccatcttaagtgatgtttataactctaatccaacg
gcagctcgacgggtcctagccgcttttgcggcggtacctactaagggtcagcgaatcgct
gtactcggtgatatgcttgagttgggtgaccagtcggatgcactacacatgagtttagcc
agtgaattggatccagccacgattgccagcgtctatttgaatggtgaacatatgcgagcg
ttggcagaagtgctacaagaaaagtacccagccggtgcggtccactattatcaaacggat
caacaaccccaattgattgccgacttaacggcgacggttagtgcggatgatcaggtctta
ttgaaggggagtcacgggattcaccttgaaaaggttctgacggcgctggaagctgctcct
gaaaaataa
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