Mycolicibacterium arabiense: MARA_05360
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Entry
MARA_05360 CDS
T07049
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
marz
Mycolicibacterium arabiense
Pathway
marz00300
Lysine biosynthesis
marz00550
Peptidoglycan biosynthesis
marz01100
Metabolic pathways
marz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
marz00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MARA_05360 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MARA_05360 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MARA_05360 (murF)
Enzymes [BR:
marz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MARA_05360 (murF)
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Ortholog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
NAD_binding_4
Motif
Other DBs
NCBI-ProteinID:
BBY47068
UniProt:
A0A7I7RR72
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Position
138892..140400
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AA seq
502 aa
AA seq
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MIELTVAEIADIVGGELADVSPDEARRLRVTGTVEFDSRAVAPGGLFLALPGARADGHDF
AAGAVAAGAVAVLAARPVGVPAIVVRPSSVSGDPDSGVLEHDTDGSGAAVLGALGRLAAA
VAARLVDGGLTIVGVTGSSGKTSTKDLLAAVLEPLGQVVAPPGSFNNELGHPWTVLRATT
DTDYLILEMSARHPGNIAALAAIAPPSIAVVLNVGTAHLGEFGSREAIAATKSELPQAVP
ASGVVILNADDKAVAAMADVTAARVVRIARQPGADLWADDVVLDELARPRFTMHSAAGSV
PVQLAVHGDHQVSNALCAAAVALECGADLEQVATALAGAGPVSRRRMQVTTRPDGVTVVN
DAYNANPDSMRAGLKALAWMAKSGADGGGERRRSWAVLGEMAELGDDAIGEHDSIGRLAV
RLDVSRLVVVGTGRSMSAMHHGAVMEGSWGSESVMVDDADSALALLRDELREGDVVLVKA
SNSAGLGVLADALAGDGGAKPA
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgagctgaccgtcgccgagatcgccgacatcgtgggtggggaactcgccgacgtg
tcgccggacgaggcacgtcgcctgcgggtcacgggcaccgtcgagttcgactcgcgcgcc
gtcgcaccgggcgggctgttcctcgcactgcccggagcgcgcgccgatggtcacgacttc
gccgcgggcgcggtggctgcgggtgcggtcgcggtgctcgccgcgcgccccgtcggcgtg
cccgcgatcgtggtccggcccagctcggtatcgggggatccggactccggggtcctcgaa
cacgacaccgacggctcgggcgccgcggtgctcggcgccctgggcaggctggcggccgcc
gtggccgcgcggctggtcgacggcggcctgacgatcgtcggcgtgacggggtcctcgggc
aagacgtcgaccaaggacctgctggcggccgtgctcgagccgctcggtcaggtggtcgcc
ccgccggggtcgttcaacaacgaactcggccatccgtggacggtgctgcgtgccaccacc
gacaccgactacctgatcctcgagatgtcggcgcgccaccccggcaacatcgccgcactg
gccgcgatcgcaccgccgtcgatcgccgtggtgctcaacgtgggcaccgcgcacctcggt
gagttcggctcgcgcgaggcgatcgcggcgacgaaatcggaactgccacaagcggttccg
gcgtccggcgtggtcatactcaacgccgacgacaaggcggtcgccgcgatggccgacgtg
acggctgcccgcgtggtgcgcatcgcccgtcagccgggcgcggatctgtgggccgacgac
gtcgtcctcgacgagctggcccggccgcggttcacgatgcactctgccgccgggtcggtg
ccggtgcagctggccgtgcacggcgatcaccaggtgtccaacgcgttgtgcgccgcggcc
gttgcgctggagtgcggggccgatctggaacaggtcgcgacggcgctcgcgggcgcgggc
ccggtgtcccggcgccgcatgcaggtgaccacccgccccgacggcgtgacggtcgtcaac
gacgcctacaacgccaatccggactcgatgcgcgccgggctcaaggcgctggcctggatg
gcgaagtcgggtgcggacgggggaggcgagcggcgccggagctgggccgtgctcggcgag
atggccgaactcggtgacgacgcgatcggtgaacatgacagcatcggacgactggccgtg
cggttggatgtgtcacgactggtcgtcgtgggaaccgggagatcgatgagcgccatgcat
cacggggccgtcatggagggatcgtggggcagtgagtcggtcatggtcgacgacgccgat
tccgcgctcgcactgctgcgcgacgagctgcgcgagggtgacgtggtgctggtgaaggcc
tccaattccgcgggtctcggcgtgctggccgatgcgctggctggcgatgggggagccaaa
cccgcatga
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