Mycobacterium tuberculosis variant bovis AF2122/97: BQ2027_MB1326
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Entry
BQ2027_MB1326 CDS
T00132
Symbol
thrA
Name
(RefSeq) PROBABLE HOMOSERINE DEHYDROGENASE THRA
KO
K00003
homoserine dehydrogenase [EC:
1.1.1.3
]
Organism
mbo
Mycobacterium tuberculosis variant bovis AF2122/97
Pathway
mbo00260
Glycine, serine and threonine metabolism
mbo00270
Cysteine and methionine metabolism
mbo00300
Lysine biosynthesis
mbo01100
Metabolic pathways
mbo01110
Biosynthesis of secondary metabolites
mbo01120
Microbial metabolism in diverse environments
mbo01230
Biosynthesis of amino acids
Module
mbo_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
mbo_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
mbo00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
BQ2027_MB1326 (thrA)
00270 Cysteine and methionine metabolism
BQ2027_MB1326 (thrA)
00300 Lysine biosynthesis
BQ2027_MB1326 (thrA)
Enzymes [BR:
mbo01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
BQ2027_MB1326 (thrA)
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Motif
Pfam:
Homoserine_dh
NAD_binding_3
ACT
GFO_IDH_MocA
Motif
Other DBs
NCBI-GeneID:
32288252
NCBI-ProteinID:
YP_009358664
Pasteur:
Mb1326
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Position
1451833..1453158
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AA seq
441 aa
AA seq
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MPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE
LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA
AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS
ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS
AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR
LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN
VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA
LDDLDVVQGVSSVIRLEGTGL
NT seq
1326 nt
NT seq
+upstream
nt +downstream
nt
gtgcccggtgacgaaaagccggtcggcgtagcggtactcggtttgggcaacgtcggcagc
gaggttgtccgcatcatcgagaacagcgccgaggatctcgcggctcgtgtcggtgcccca
ttggtcctgcggggcatcggcgtgcgccgcgtgacgaccgatcgcggcgtgccgatcgaa
ttgttgaccgacgacattgaagagctcgtggcccgcgaggatgtcgatatcgtggtggaa
gtgatggggccggtggaaccgtcgcgcaaggcgatcctgggcgcccttgagcgcggcaag
tccgtcgttacggcgaacaaggctttactcgccacctccaccggcgaattggcacaggcc
gccgaaagcgcccatgttgatctgtatttcgaggcggccgtggcgggcgccattccggtc
atccgtccgctcacccagtcgctggccggcgacacggtgctgcgagtggccgggatcgtc
aacggcaccaccaactacatcctctcggcgatggacagcaccggcgctgactatgccagc
gccctggccgacgcaagtgcgctgggctatgcggaggctgatcccaccgcagacgtcgaa
ggctacgacgccgcggccaaggcagcgatcctggcatccattgccttccacacccgggtg
accgcagacgacgtgtatcgcgaaggcatcaccaaggtcactccggccgacttcggatcc
gcgcacgcgctgggttgcaccatcaaactgctgtcgatctgtgagcgcataaccaccgac
gaaggttcgcagcgggtatcggcccgcgtctatccggccctggtacctctgtcgcatccg
cttgccgcggtcaacggcgcgttcaatgccgtggtggtcgaggccgaggccgcgggccgg
ctgatgttctacggccagggcgcgggcggcgcgccgaccgcctctgcggtgaccggtgac
ctagtgatggccgcccgcaaccgggtactcggcagccgcggcccccgtgagtctaaatac
gctcaacttccggtggcaccaatgggtttcattgaaacgcgctattacgtcagcatgaac
gtcgccgacaagccgggcgtcttgtccgcggtggcggcggaattcgccaaacgcgaggtg
agcatcgccgaggtgcgccaggagggcgttgtggacgaaggtggtcgacgggtgggagcc
cgaatcgtggtggtcacgcacctcgccactgacgccgcactctcggaaaccgttgatgca
ctggacgacttggatgtcgtgcagggtgtgtccagcgtgatacgactggaaggaaccggc
ttatga
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