Macaca mulatta (rhesus monkey): 677709
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Entry
677709 CDS
T01028
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
677709 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mcc03032
]
677709 (TOP2B)
03036 Chromosome and associated proteins [BR:
mcc03036
]
677709 (TOP2B)
Enzymes [BR:
mcc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
677709 (TOP2B)
DNA replication proteins [BR:
mcc03032
]
Eukaryotic type
DNA Topoisomerases
677709 (TOP2B)
Chromosome and associated proteins [BR:
mcc03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
677709 (TOP2B)
Centrosome formation proteins
Centriole proteins
677709 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
Motif
Other DBs
NCBI-GeneID:
677709
NCBI-ProteinID:
NP_001252630
Ensembl:
ENSMMUG00000007371
UniProt:
I2CT72
LinkDB
All DBs
Position
2:21996833..22063377
Genome browser
AA seq
1621 aa
AA seq
DB search
MAKSGGCGAGAGVGGGNGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL
LRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC
IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG
YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS
KFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV
ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK
NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN
CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDS
AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDD
AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK
QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE
DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI
LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL
MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDN
LLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLD
PHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPML
NGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFD
HMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIT
IENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNY
ILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQERE
DILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRVIPEITAMKADASKKLLKKKKGDL
DTTAVKVEFDEEFSGVPVEGAGEEALIPSAPINKGPKPKREKKEPGTRVRKTPTSSGKPS
AKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD
DDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFG
NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQIDKVPSKTVAAKKGKPSSDTAP
KPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS
KTASKKPKKTSFDQDSDVDIFPSDFPSEPPSLPRTGRARKEVKYFAESDEEEEDVDFAMF
N
NT seq
4866 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtcgggtggctgcggcgcgggagccggcgtgggcggcggcaacggtgcactg
acctgggtgaacaatgctgcaaaaaaagaagagtcagaaactgccaacaaaaatgattct
tcaaagaagttgtctgttgagagagtgtatcagaagaagacacaacttgaacacattctt
cttcgtcctgatacatatattgggtcagtggagccattgacgcagttcatgtgggtgtat
gatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggtttatacaagatc
tttgatgaaattttggttaatgctgctgacaataaacagagggataagaacatgacttgt
attaaagtttctattgatcctgaatctaacattataagcatttggaataatggaaaaggc
attccagtagtagaacacaaggtagagaaagtttatgttcctgctttaatttttggacag
cttttaacatccagtaactatgatgatgatgagaaaaaagttacaggtggtcgtaatggt
tatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaacagcttgcaaa
gaatacaaacacagttttaagcagacatggatgaataatatgatgaagacttctgaagcc
aaaattaaacattttgatggtgaagattacacatgcataacattccaaccagatctgtcc
aaatttaagatggaaaaacttgacaaggatattgtggccctcatgaccagaagggcatat
gatttggctggttcatgtaaaggggtcaaggtcatgtttaatggaaagaaattgcctgta
aatggatttcgcagttatgtagatctttatgtgaaagacaaattggatgaaactggggtg
gccctgaaagttattcatgagcttgcaaatgaaagatgggatgtttgtctcacattgagt
gaaaaaggattccagcagatcagctttgtaaatagtattgcgactacaaaaggtggacgg
cacgtggattatgtggtagatcaagttgttggtaaactgattgaagtggttaagaaaaag
aacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccatatatgggtttttatt
aattgccttattgaaaatccaacttttgattctcagactaaggaaaacatgactctgcag
cccaaaagttttgggtctaaatgccagctgtcagaaaaattttttaaagcagcctctaat
tgtggcattgtagaaagtatcctaaactgggtgaaatttaaggctcagactcagctgaat
aagaagtgttcatcagtaaaatacagtaaaatcaaaggtattcccaaactggatgacgct
aatgatgctggtggcaaacattccctggagtgtacactgatattaacagagggagactct
gccaaatcactggctgtgtctggattaggtgtgattggacgagacagatacggagttttt
ccactcaggggcaaaattcttaacgtacgggaagcttctcataaacagatcatggaaaat
gctgaaataaataatattattaaaatagttggtctacaatataagaaaagttacgatgat
gcagaatctctgaaaaccttacgctatggaaagattatgattatgaccgatcaggatcaa
gatggttctcacataaaaggcctgcttattaatttcatccatcacaattggccatcactt
ttgaagcatggttttcttgaagagttcattactcctattgtcaaggcaagcaaaaataag
caggaactttccttctacagtattcctgaatttgatgagtggaaaaaacatatagaaaat
cagaaagcctggaaaatcaagtactataaaggattgggtactagtacagctaaagaagca
aaggaatattttgctgatatggaaaggcatcgcatcttgtttagatacgctggtcctgaa
gatgatgctgccattaccttggcattcagtaagaagaagattgatgacagaaaagaatgg
ttaacaaattttatggaagaccggagacagcgtaggctacatggcttaccagagcaattt
ttatatggtactgcaacaaagcatttgacttacaatgatttcatcaacaaggaattgatt
ctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggctttaaacct
ggccagcggaaagttttatttacctgtttcaagaggaatgataaacgtgaagtaaaagtt
gcccagttggctggatctgttgctgagatgtcggcttatcatcatggagaacaagcattg
atgatgactattgtgaatttggctcagaactttgtgggaagtaacaacattaacttgctt
cagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgcaagccctcgt
tatattttcacaatgttaagctctttagcaaggctactttttcctgccgtggatgacaac
ctgcttaagttcctttatgatgataatcaacgtgtagagcctgagtggtatattcccata
attcccatggttttaataaatggtgctgagggcattggtactggatgggcttgtaaacta
cccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagatggcttggat
cctcatcccatgcttccaaactacaaaaactttaaagggacgattcaagaacttggtcaa
aaccagtatgcagtcagtggtgaaatatttgtagtggacagaaacacagtagaaattaca
gagcttccagttagaacttggacacaggtatacaaagaacaggttttagaacctatgcta
aatggaacagataaaacaccagcattaatttctgattataaagaatatcatactgacaca
actgtgaaatttgtggtgaaaatgactgaagagaaactagcgcaagcagaagctgctgga
ctgcataaagtttttaaacttcaaactactcttacttgtaattccatggtactctttgat
catatgggatgtctgaagaaatatgaaactgtgcaagacattctgaaagaattctttgat
ttacgattaagttattatggtttacgtaaggagtggcttgtgggaatgctgggagcagaa
tctacaaagcttaacaatcaagcccgtttcattttagagaagatacaagggaaaattact
atagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaatct
gacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggatgaaacacaa
aaccagcatgatgatagttcctccgattcaggaactccttcaggcccagattttaattat
attttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactgattaaacag
agagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctccttcagatctttgg
aaagaagatttagcagcgtttgttgaagaactggataaagtggaagctcaagaacgagaa
gatattctggctggaatgtctggaaaagcaattaaaggtaaagttggcaaacctaaggtg
aagaaactccaattggaagagacaatgccctcaccttatggcagaagagtaattcctgaa
attacagctatgaaggcagatgccagcaaaaagttgctgaagaagaagaagggtgatctt
gatactacagcagtaaaagtggaatttgatgaagaattcagtggagtgccagtagaaggt
gcaggagaagaggcattgattccgtcagctcctataaataaaggccccaaacccaaaagg
gagaagaaggagcctggtaccagagtgagaaaaacacccacatcatctggtaaacctagt
gcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtcagaaagtgac
ttggaagaaacagaacctgtggttattccaagagattctttgcttaggagagcagccgcc
gaaagacctaaatacacatttgatttctcagaagaagaggatgatgatgctgatgatgat
gatgatgacaataatgatttagaagaattgaaagttaaagcatctccaataacaaatgat
ggggaagatgaatttgttccttcagatgggttagataaagatgaatatacattttcacca
ggcaaatcaaaagccactccagaaaaatctttgcatgacaaaaaaagtcaggattttgga
aatctcttttcatttccttcatattctcagaagtcagaagatgattcagctaaatttgac
agtaatgaagaagattctgcctcagttttctcaccatcatttggtctgaaacagatagat
aaagttccaagtaaaacagtagctgctaaaaagggaaaaccgtcttcagatacagcccct
aagcccaagagagcccccaaacagaagaaagtagtagaggctgtaaactctgactcagat
tcagaatttggcattccaaagaagactacaacaccaaaaggtaaaggccgaggggcaaag
aaaaggaaagcatctggctctgaaaatgaaggcgactataaccctggcaggaaaacatcc
aaaacagcaagcaagaaaccgaagaaaacatcctttgatcaggattcagatgtggacatc
ttcccctcagacttcccttctgagccaccttctctgccacgaaccggtcgggctaggaaa
gaagtaaaatattttgcagagtctgatgaagaagaagaagatgttgattttgcaatgttt
aattaa
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integrated database retrieval system
