Macaca mulatta (rhesus monkey): 693666 Help Entry 693666            CDS       T01028                                  Gene name ACTN4 Definition (RefSeq) alpha-actinin-4   KO K05699   actinin alpha 1/4 Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc04510   Focal adhesion mcc04520   Adherens junction mcc04530   Tight junction mcc04670   Leukocyte transendothelial migration mcc04810   Regulation of actin cytoskeleton mcc05146   Amoebiasis mcc05203   Viral carcinogenesis mcc05322   Systemic lupus erythematosus Brite KEGG Orthology (KO) [BR:mcc00001]  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     693666 (ACTN4)    04520 Adherens junction     693666 (ACTN4)    04530 Tight junction     693666 (ACTN4)   09142 Cell motility    04810 Regulation of actin cytoskeleton     693666 (ACTN4)  09150 Organismal Systems   09151 Immune system    04670 Leukocyte transendothelial migration     693666 (ACTN4)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     693666 (ACTN4)   09163 Immune disease    05322 Systemic lupus erythematosus     693666 (ACTN4)   09174 Infectious disease: parasitic    05146 Amoebiasis     693666 (ACTN4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mcc04131]     693666 (ACTN4)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:mcc04812]     693666 (ACTN4)    04147 Exosome [BR:mcc04147]     693666 (ACTN4) Membrane trafficking [BR:mcc04131]  Exocytosis   Small GTPases and associated proteins    Rab associated proteins     693666 (ACTN4) Cytoskeleton proteins [BR:mcc04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Cross-linking proteins      693666 (ACTN4) Exosome [BR:mcc04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    693666 (ACTN4)   Exosomal proteins of colorectal cancer cells    693666 (ACTN4)   Exosomal proteins of bladder cancer cells    693666 (ACTN4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin CH EFhand_Ca_insen EF-hand_1 EF-hand_6 CAMSAP_CH EF-hand_7 EF-hand_8 Motif Other DBs NCBI-GeneID:  693666 NCBI-ProteinID:  NP_001248731 Ensembl:  ENSMMUG00000006429 UniProt:  A0A1D5QZ63 LinkDB All DBs Position 19 AA seq 911 aa AA seqDB search MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWC NSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIA SKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPY KNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKM LDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYEK LASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTL QTKLRLSNRPAFMPSEGKMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQ KASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQEL NELDYYDSHNVNTRCQKICDQWDALGSLTHSRREALEKTEKQLEAIDQLHLEYAKRAAPF NNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAES NHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANV VGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQQHQLIQEALIF DNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKD HGGALGPEEFKACLISLGYDVENDRQGEAEFNRIMSLVDPNHSGLVTFQAFIDFMSRETT DTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKS FSTALYGESDL NT seq 2736 nt NT seq  +upstreamnt  +downstreamnt atggtggactaccacgcggcgaaccagtcgtaccagtacggccccagcagcgcgggcaat ggcgctggcggcgggggcagcatgggcgactacatggcccaggaggacgactgggaccgg gacctgctgctggacccggcctgggagaagcagcagcgcaagaccttcacggcgtggtgc aactcccacctgcggaaggcaggcacgcagatcgagaacatcgacgaggacttccgagac gggctgaagctcatgttgctcctggaggtcatatcaggggagcggttacctaagccggag cgggggaaaatgagagtgcacaaaatcaacaacgtgaacaaagcactggactttattgcc agcaaaggcgtcaagctggtctccatcggggcagaagagattgtggacggcaacgcaaag atgaccctgggaatgatctggaccatcatccttaggttcgccatccaggacatctccgtg gaagagacctcggccaaggaagggcttcttctctggtgccagagaaagacagccccgtat aagaacgtcaacgtgcagaacttccacattagctggaaggacggtcttgccttcaatgcc ctgatccaccggcacagaccagagctgattgagtatgacaagctgaggaaggacgaccct gttaccaacctgaacaatgccttcgaagtggctgagaaatacctcgacatccccaagatg ctggatgcagaggacatcgtgaacacggcccgccccgacgagaaggccataatgacctat gtgtccagcttctaccatgccttttcgggagcgcagaaggctgaaactgctgccaatcgg atctgcaaggtgctggctgtcaaccaagagaacgagcacctgatggaggactacgagaag ctggccagcgacctcctggagtggatccggcgcaccatcccctggctggaggaccgtgtg ccccaaaagactatccaggagatgcagcagaagctagaggacttccgtgactaccggcgc gtgcacaagccacccaaggtgcaggagaagtgccagctggagatcaacttcaacacgctg cagaccaagctgcgcctcagcaaccggcctgccttcatgccctctgagggcaagatggtc tcggacatcaacaacggctggcagcacttggagcaggctgagaagggctatgaggagtgg ttgctgaatgagatccgcaggctggagcggctcgaccacctggcagagaagttccggcag aaggcctccatccacgaggcctggactgacgggaaggaagccatgctgaagcaccgggac tacgagacggccaccctgtcggacatcaaagccctcattcgcaagcacgaggccttcgag agcgacctggccgcgcaccaagaccgcgtggagcagatcgccgccattgcccaggagctc aacgagctggattactacgactcccacaatgtcaacacccggtgccagaagatctgcgac cagtgggacgccctcggctctctgacccacagtcgcagggaagccctggagaaaacagag aagcagctggaggccatcgaccagctgcacctggagtatgccaagcgcgcggcccccttc aacaactggatggagagcgccatggaggacctccaggacatgttcatcgtccacaccatc gaggagattgagggcctgatctcagcccatgaccagttcaagtccaccttgccggacgcc gacagggagcgcgaggccatcctggccatccacaaggaggcccagaggattgctgagagc aaccacatcaagctgtcgggcagcaacccctacaccactgtcaccccgcagatcatcaac tccaagtgggagaaggtgcagcagctggtgccaaaacgggaccatgccctcctggaggag cagagcaagcagcagtccaatgagcacctgcgccgccagtttgccagccaggccaacgtc gtgggcccctggatccagaccaagatggaggagatcgggcgcatctccattgagatgaac gggaccctggaggaccagctgagccacctgaagcagtatgaacgcagcatcgtggactac aagcccaacctggacctgctggagcagcagcaccagctcatccaggaggccctcatcttc gacaacaagcacaccaactacaccatggagcacattcgcgtgggctgggagcagctgctc accaccattgcccgcaccatcaacgaggtggagaaccagatcctcacccgcgacgccaag ggcatcagccaggagcagatgcaggagttccgggcatccttcaaccacttcgacaaggac catggcggggcgctggggcccgaggagttcaaggcctgcctcatcagcctgggctacgac gtggagaacgaccggcagggtgaggccgagttcaaccgcatcatgagcctggttgacccc aaccacagcggccttgtgaccttccaagccttcatcgacttcatgtctcgggagaccacc gacaccgacacggccgaccaggtcatcgcctccttcaaggtcctggcaggggacaagaac ttcatcacagctgaggagctgcggagagagctgccccccgaccaggctgagtactgcatt gcccgcatggcaccgtaccagggccccgacgctgtgcccggcgccctcgactacaagtcc ttctccacagccctgtatggcgagagcgacctgtga

Macaca mulatta (rhesus monkey): 711994 Help Entry 711994            CDS       T01028                                  Gene name ACTN1 Definition (RefSeq) alpha-actinin-1 isoform X1   KO K05699   actinin alpha 1/4 Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc04510   Focal adhesion mcc04520   Adherens junction mcc04530   Tight junction mcc04670   Leukocyte transendothelial migration mcc04810   Regulation of actin cytoskeleton mcc05146   Amoebiasis mcc05203   Viral carcinogenesis mcc05322   Systemic lupus erythematosus Brite KEGG Orthology (KO) [BR:mcc00001]  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     711994 (ACTN1)    04520 Adherens junction     711994 (ACTN1)    04530 Tight junction     711994 (ACTN1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     711994 (ACTN1)  09150 Organismal Systems   09151 Immune system    04670 Leukocyte transendothelial migration     711994 (ACTN1)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     711994 (ACTN1)   09163 Immune disease    05322 Systemic lupus erythematosus     711994 (ACTN1)   09174 Infectious disease: parasitic    05146 Amoebiasis     711994 (ACTN1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mcc04131]     711994 (ACTN1)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:mcc04812]     711994 (ACTN1)    04147 Exosome [BR:mcc04147]     711994 (ACTN1) Membrane trafficking [BR:mcc04131]  Exocytosis   Small GTPases and associated proteins    Rab associated proteins     711994 (ACTN1) Cytoskeleton proteins [BR:mcc04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Cross-linking proteins      711994 (ACTN1) Exosome [BR:mcc04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    711994 (ACTN1)   Exosomal proteins of colorectal cancer cells    711994 (ACTN1)   Exosomal proteins of bladder cancer cells    711994 (ACTN1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin CH EFhand_Ca_insen EF-hand_1 EF-hand_8 EF-hand_6 EF-hand_7 CAMSAP_CH EF-hand_5 XisI Motif Other DBs NCBI-GeneID:  711994 NCBI-ProteinID:  XP_014999455 Ensembl:  ENSMMUG00000010767 UniProt:  A0A1D5QE04 LinkDB All DBs Position 7 AA seq 914 aa AA seqDB search MDHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFR DGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNV KMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFC ALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMT YVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENR VPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRM VSDINNAWGCLEQVEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQK DYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKIC DQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHT IEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEI NGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEM HGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQL LTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGY DIGNDPQKKTGMMDTDDFRACLISMGYNMGEAEFARIMSIVDPNRLGVVTFQAFIDFMSR ETADTDTADQVMASFKILAGDKNYITVDELRRELPPDQAEYCIARMAPYTGPDSVPGALD YMSFSTALYGESDL NT seq 2745 nt NT seq  +upstreamnt  +downstreamnt atggaccattatgattctcagcaaaccaacgattacatgcagccagaagaggactgggac cgggacctgctcctggacccggcctgggagaagcagcagagaaagacattcacggcatgg tgtaactcccacctccggaaggcggggacgcagattgagaacatcgaagaggacttccgg gatggcctgaagctcatgctgctgctggaggtcatatcaggtgaacgcttggccaagcca gagcgaggcaagatgagggtgcacaagatctccaacgtcaacaaggccctggatttcata gccagcaaaggcgtcaaactggtgtccatcggagccgaagaaatcgtggatgggaatgtg aagatgaccctgggcatgatctggaccatcatcctgcgctttgccatccaggacatctcc gtggaagagacttcagccaaggaagggctgctcctgtggtgtcaaagaaagacggcccct tacaaaaacgtcaacatccagaacttccacataagctggaaggatggcctcggcttctgt gccttgatccaccgacaccggcccgagctgattgactacgggaagctgcggaaggatgat ccactcacaaatctgaatacagcttttgatgtggcagagaagtacctggacatccccaag atgctggatgccgaagacatcgttggaactgcccgaccggatgagaaagccatcatgact tacgtgtctagcttctaccacgccttctctggagcccagaaggcggagacagcagccaat cgcatctgcaaggtgttggccgtcaaccaggagaacgagcagcttatggaagactacgag aagctggccagtgatctgttggagtggatccgccgcaccatcccgtggctggagaaccgg gtgcccgagaacaccatgcatgccatgcagcagaagctggaggacttccgggactaccgg cgcctgcacaagccgcccaaggtgcaggagaagtgccagctggagatcaacttcaacacg ctgcagaccaagctgcggctcagcaaccggcccgccttcatgccctccgagggcaggatg gtctcggacatcaacaatgcctggggctgcctggagcaggtggagaagggctatgaggag tggttgctgaacgagatccggaggctggagcgactggaccacctggcagagaagttccgg cagaaggcctccatccacgaggcctggactgacggcaaagaggccatgctgcgacagaag gactatgagacggccaccctctcggagatcaaggccctgctcaagaagcatgaggccttc gagagtgacctggctgcccaccaggaccgcgtggagcagattgccgccatcgcacaggaa ctcaatgagctggactattatgactcacccagtgtcaacgcccgttgccaaaagatctgt gaccagtgggacaatctgggggccctaactcagaagcgaagggaagctctggagcggacc gagaaactgctggagaccattgaccagctgtacttggagtatgccaagagggccgcaccc ttcaacaactggatggagggggccatggaggacctgcaggacaccttcattgtgcacacc attgaggagatccagggactgaccacagcccatgagcagttcaaggccaccctccctgat gctgataaggagcgtctggctatcctgggcatccacaacgaggtgtccaagattgtccag acctaccacgtcaatatggcgggcaccaacccctacacaaccatcacgcctcaggagatc aatggcaaatgggaccacgtgcggcagctggtgcctcggagggaccaagctctgacggag gagcacgcccgacagcagcacaatgagaggctacgcaagcagtttggggcacaggccaat gtcatcgggccctggatccagaccaagatggaggagattgggaggatctccattgagatg cacgggaccctggaggaccagctcagccacctgcggcagtatgagaagagcattgtcaac tacaagccaaagattgatcagctggagggcgaccaccagctcatccaggaggcgctcatc ttcgacaacaagcacaccaactacaccatggagcacatccgtgtgggctgggagcagctg ctcaccaccatcgccaggaccatcaacgaggtggagaaccagatcctgacccgggatgcc aagggcattagccaggagcagatgaatgagttccgggcctccttcaaccactttgaccgg gatcactccggcacactgggtcccgaggagttcaaagcctgcctcatcagcttgggttat gatattggcaacgacccccagaagaagacaggcatgatggacacggatgatttccgcgcc tgcctgatctccatgggttacaacatgggagaagcagaatttgcccgcatcatgagcatt gtggaccccaaccgcctgggggtagtgacattccaggccttcattgacttcatgtcccgt gagacagccgatacagatacagcagaccaagtcatggcttccttcaagatcctggctggg gacaagaactacattaccgtggacgagctgcgccgcgagctgccgcctgaccaggccgag tactgcatcgcgcggatggccccctacaccggccccgactccgtgccaggtgctctggac tacatgtccttctccacggcactgtacggcgagagtgacctctaa

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