KEGG   Manis javanica (Malayan pangolin): 108386068
Entry
108386068         CDS       T06054                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv01521  EGFR tyrosine kinase inhibitor resistance
mjv04062  Chemokine signaling pathway
mjv04066  HIF-1 signaling pathway
mjv04068  FoxO signaling pathway
mjv04217  Necroptosis
mjv04550  Signaling pathways regulating pluripotency of stem cells
mjv04630  JAK-STAT signaling pathway
mjv04659  Th17 cell differentiation
mjv04917  Prolactin signaling pathway
mjv04920  Adipocytokine signaling pathway
mjv04931  Insulin resistance
mjv04933  AGE-RAGE signaling pathway in diabetic complications
mjv04935  Growth hormone synthesis, secretion and action
mjv05145  Toxoplasmosis
mjv05160  Hepatitis C
mjv05161  Hepatitis B
mjv05162  Measles
mjv05163  Human cytomegalovirus infection
mjv05167  Kaposi sarcoma-associated herpesvirus infection
mjv05169  Epstein-Barr virus infection
mjv05200  Pathways in cancer
mjv05203  Viral carcinogenesis
mjv05205  Proteoglycans in cancer
mjv05206  MicroRNAs in cancer
mjv05212  Pancreatic cancer
mjv05221  Acute myeloid leukemia
mjv05223  Non-small cell lung cancer
mjv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mjv05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    108386068 (STAT3)
   04066 HIF-1 signaling pathway
    108386068 (STAT3)
   04068 FoxO signaling pathway
    108386068 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    108386068 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    108386068 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    108386068 (STAT3)
   04062 Chemokine signaling pathway
    108386068 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    108386068 (STAT3)
   04917 Prolactin signaling pathway
    108386068 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    108386068 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108386068 (STAT3)
   05206 MicroRNAs in cancer
    108386068 (STAT3)
   05205 Proteoglycans in cancer
    108386068 (STAT3)
   05203 Viral carcinogenesis
    108386068 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108386068 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    108386068 (STAT3)
   05221 Acute myeloid leukemia
    108386068 (STAT3)
   05223 Non-small cell lung cancer
    108386068 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    108386068 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    108386068 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    108386068 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    108386068 (STAT3)
   05161 Hepatitis B
    108386068 (STAT3)
   05160 Hepatitis C
    108386068 (STAT3)
   05163 Human cytomegalovirus infection
    108386068 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    108386068 (STAT3)
   05169 Epstein-Barr virus infection
    108386068 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    108386068 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    108386068 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mjv03000]
    108386068 (STAT3)
Transcription factors [BR:mjv03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    108386068 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Fib_alpha
Other DBs
NCBI-GeneID: 108386068
NCBI-ProteinID: XP_017499223
LinkDB
Position
Unknown
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccagtggaatcagctacagcagctcgacactcggtacctggagcagctacatcag
ctgtacagtgacagcttcccgatggagctacggcagtttctggccccttggattgaaagt
caagactgggcatatgcagccagcaaagaatcacatgccactttggtgttccataatctc
ttgggtgagattgaccagcagtacagccgcttcctgcaagagtcaaatgttctctatcag
cacaatctgcgaagaatcaagcagttccttcagagtagataccttgagaagccaatggag
atcgcccgaattgtggcccggtgcctgtgggaagagtcccgcctcctccagacggcagcc
acagctgcccagcaagggggccaggccaaccaccccacagctgccgtggtgacagagaag
cagcaaatgctggagcagcacctgcaggatgtccggaagcgagtacaggatctagaacag
aaaatgaaagtggtagagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaagatctgaatggaaacaaccagtcggtgaccaggcagaagatg
cagcaactggaacagatgctcaccgcgctggaccagatgcggcgaagcatcgtgagtgag
ctggcgggacttttgtcagctatggagtatgtgcagaaaaccctcacggatgaagagctg
gctgactggaagaggcggcaacagattgcttgcattggaggccctcccaacatctgtcta
gatcgtctggaaaactggataacctcattagcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagttgcagcaaaaagtttcctacaaaggggaccccatcgtacag
caccggccaatgctggaggagagaatcgtggagctgtttagaaacttaatgaaaagtgcc
tttgtggttgagcgacagccttgtatgcccatgcatcccgaccggccactcgtcatcaag
accggtgtccagtttactacgaaagtcagattgctggtcaaattccctgagttaaattac
cagcttaaaattaaagtgtgcattgacaaagactccggggatgttgcagctctcagggga
tcccggaaatttaacattctgggcacaaacacgaaagtgatgaacatggaagagtccaac
aacggcagcctctctgcagaattcaaacacttgactctgagagagcaaagatgtggtaac
gggggccgagccaattgtgatgcctccctgattgtgaccgaggagctgcacctgatcacc
tttgagactgaggtgtatcaccaaggcctcaagattgacctggagactcactccttgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcctgggcatccatcctgtggtat
aacatgctgaccaacaacccgaagaacgtgaactttttcaccaagcccccaattggaact
tgggatcaagtggctgaggtgctgagctggcagttctcctccaccacaaagcgagggctg
agcatcgagcagttgactacgctggcagagaaactcttgggacctggcgtgaactattca
ggatgtcagatcacctgggctaaattttgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctggacaatatcattgaccttgtgaaaaagtacatcctggctctttgg
aatgaaggatacattatgggctttatcagtaaggagcgggaacgggccatattgagcacc
aagcccccaggcaccttcctgctaagattcagtgaaagcagcaaagaaggaggcgtcacc
ttcacctgggtagagaaggacatcagcggcaagacccagatccagtcggtggaaccatat
acgaagcagcagctgaacaacatgtcgtttgctgaaatcatcatgggctataaaatcatg
gatgctaccaatattctcgtgtctccgctggtctacctctaccccgacattcctaaggag
gaggcatttggaaagtattgtcggccagagagccaggagcatcctgaagctgacccaggt
agtgctgccccgtacctgaagaccaagtttatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgaaccctcagccggagggcagtttgagtccctcacgttcgacatggag
ttgacctcagagtgcgcaacctccccgatgtga

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