Mycobacterium tuberculosis variant microti: RN08_1272
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Entry
RN08_1272 CDS
T04291
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
mmic
Mycobacterium tuberculosis variant microti
Pathway
mmic00270
Cysteine and methionine metabolism
mmic00450
Selenocompound metabolism
mmic01100
Metabolic pathways
mmic01110
Biosynthesis of secondary metabolites
mmic01230
Biosynthesis of amino acids
Module
mmic_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
mmic00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
RN08_1272
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
RN08_1272
Enzymes [BR:
mmic01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
RN08_1272
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Gene cluster
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
VbhA
SHOCT
Motif
Other DBs
NCBI-ProteinID:
AMC58699
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Position
complement(1262451..1264730)
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AA seq
759 aa
AA seq
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MTQPVRRQPFTATITGSPRIGPRRELKRATEGYWAGRTSRSELEAVAATLRRDTWSALAA
AGLDSVPVNTFSYYDQMLDTAVLLGALPPRVSPVSDGLDRYFAAARGTDQIAPLEMTKWF
DTNYHYLVPEIGPSTTFTLHPGKVLAELKEALGQGIPARPVIIGPITFLLLSKAVDGAGA
PIERLEELVPVYSELLSLLADGGAQWVQFDEPALVTDLSPDAPALAEAVYTALCSVSNRP
AIYVATYFGDPGAALPALARTPVEAIGVDLVAGADTSVAGVPELAGKTLVAGVVDGRNVW
RTDLEAALGTLATLLGSAATVAVSTSCSTLHVPYSLEPETDLDDALRSWLAFGAEKVREV
VVLARALRDGHDAVADEIASSRAAIASRKRDPRLHNGQIRARIETIVASGAHRGNAAQRR
ASQDARLHLPPLPTTTIGSYPQTSAIRVARAALRAGEIDEAEYVRRMRQEITEVIALQER
LGLDVLVHGEPERNDMVQYFAEQLAGFFATQNGWVQSYGSRCVRPPILYGDVSRPRAMTV
EWITYAQSLTDKPVKGMLTGPVTILAWSFVRDDQPLADTANQVALAIRDETVDLQSAGIA
VIQVDEPALRELLPLRRADQAEYLRWAVGAFRLATSGVSDATQIHTHLCYSEFGEVIGAI
ADLDADVTSIEAARSHMEVLDDLNAIGFANGVGPGVYDIHSPRVPSAEEMADSLRAALRA
VPAERLWVNPDCGLKTRNVDEVTASLHNMVAAAREVRAG
NT seq
2280 nt
NT seq
+upstream
nt +downstream
nt
gtgacccagcctgtacgtcgtcaaccctttaccgcaaccatcaccggctccccgcgcatc
ggcccgcgccgcgaactcaagcgcgccaccgaaggctactgggccggacgtaccagccga
tccgagctggaggccgtcgccgccacgttacgccgcgacacctggtcggccctggccgcg
gccggtctggactcggtgccggtgaacaccttctcctactacgaccaaatgctcgatacc
gcggtgctgctcggcgcgctgccgccccgagtgagcccggtttccgacgggctggaccgc
tatttcgccgcggcgcggggcaccgaccagatcgcgccgctggagatgacgaagtggttc
gacaccaactaccactacctggtacccgagatcgggccgtcgaccacgttcacgctgcac
cccggcaaggtgctcgccgaactcaaagaggcgttagggcaaggcattcccgcacgtccg
gtgatcatcgggccgatcaccttcctgctgctgagcaaggccgtcgacggcgcgggggcg
ccgatcgaacgcctcgaagagttggttccggtctattcggagctgctgtcgctgcttgcc
gacggcggcgcccagtgggtgcagttcgacgagccggcgctggtgaccgacctctccccc
gacgcgcccgccctggctgaagcggtgtacaccgcgctgtgctcggtgagcaaccggcct
gcgatctatgtcgccacctacttcggggacccgggcgcggccctaccggcgctggctcgc
accccggtcgaagccatcggcgtcgacctggtggccggtgccgacacctcggtggccggg
gtacccgagctggccggcaagacgctggtggccggggtcgtcgacgggcgcaacgtctgg
cgcaccgacctggaggcggcgttgggcacgttggcgaccctgctgggttcggcggctacc
gtggccgtctcgacgtcgtgctcgacactgcacgtgccgtactcgctggaaccggaaacc
gacctggatgacgcgttgcggagctggctggcgttcggtgccgaaaaggtgcgcgaagtc
gtcgttctcgcgcgtgccctgcgcgacggacacgacgcggtcgccgacgagatcgcgtcg
tcccgcgccgccatcgcgtcccgcaagcgcgacccgcggttacacaatgggcaaatccgg
gcgcgcatcgagacgatcgtcgcgtccggagcccaccgcggcaatgccgcccagcgccgc
gccagccaagacgcgcgactgcacctgccgccgctgccgaccacgacgatcggctcctac
ccgcagacctcggcgatccgcgttgcgcgtgcggcgctgcgggccggtgagatcgacgag
gccgagtacgtgcgccggatgcggcaagagatcaccgaggtgatcgcgctacaggagcgg
ctcgggctcgacgtgctggtgcacggcgaaccggagcgcaacgacatggtgcagtacttc
gccgagcaattggcgggtttcttcgctacccagaacggctgggtgcagtcctacggcagc
cgctgtgtgcgtccgccgatcctgtacggcgacgtgtcccggccgcgggcgatgacggtc
gagtggatcacctacgcgcagtcgctgaccgacaaaccggtgaagggcatgttgaccggg
ccggtgacgattctggcgtggtcgttcgtgcgcgacgaccagccgttggccgataccgcc
aaccaggtggcgctggcgattcgcgacgagaccgtggatttgcagtccgccggcatcgcg
gtcatccaggtcgacgagcctgcgctgcgtgaactgctgccgctgcgtcgcgccgaccag
gccgagtacttgcgttgggcggtaggggctttccggttggccacctccggcgtctcggac
gccacccagatccacacgcatctgtgctactcggagttcggcgaggtgatcggcgcgatc
gccgatctggacgcggacgtcacgtccatcgaggcggcccggtcacacatggaggtgctc
gacgacctgaacgcgatcggcttcgccaacggtgtgggcccgggcgtctatgacattcac
tcgccacgggtgccctccgctgaggagatggccgactcgttgcgggccgcgttgcgcgcg
gtgccggccgagcggctgtgggtcaaccccgactgcggactgaagacccgcaatgtcgac
gaggtgaccgcgtcgctgcacaacatggtcgccgccgcccgggaggtgcgcgcgggctag
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