Mus musculus (house mouse): 104111 Help Entry 104111            CDS       T01002                                  Symbol Adcy3, AC3, ACIII, mKIAA0511 Name (RefSeq) adenylate cyclase 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism mmu  Mus musculus (house mouse) Pathway mmu00230   Purine metabolism mmu01100   Metabolic pathways mmu01522   Endocrine resistance mmu04015   Rap1 signaling pathway mmu04020   Calcium signaling pathway mmu04022   cGMP-PKG signaling pathway mmu04024   cAMP signaling pathway mmu04062   Chemokine signaling pathway mmu04072   Phospholipase D signaling pathway mmu04081   Hormone signaling mmu04082   Neuroactive ligand signaling mmu04114   Oocyte meiosis mmu04211   Longevity regulating pathway mmu04213   Longevity regulating pathway - multiple species mmu04261   Adrenergic signaling in cardiomyocytes mmu04270   Vascular smooth muscle contraction mmu04371   Apelin signaling pathway mmu04540   Gap junction mmu04611   Platelet activation mmu04713   Circadian entrainment mmu04714   Thermogenesis mmu04723   Retrograde endocannabinoid signaling mmu04724   Glutamatergic synapse mmu04725   Cholinergic synapse mmu04727   GABAergic synapse mmu04740   Olfactory transduction mmu04750   Inflammatory mediator regulation of TRP channels mmu04911   Insulin secretion mmu04912   GnRH signaling pathway mmu04913   Ovarian steroidogenesis mmu04914   Progesterone-mediated oocyte maturation mmu04915   Estrogen signaling pathway mmu04916   Melanogenesis mmu04918   Thyroid hormone synthesis mmu04921   Oxytocin signaling pathway mmu04923   Regulation of lipolysis in adipocytes mmu04925   Aldosterone synthesis and secretion mmu04926   Relaxin signaling pathway mmu04927   Cortisol synthesis and secretion mmu04928   Parathyroid hormone synthesis, secretion and action mmu04934   Cushing syndrome mmu04935   Growth hormone synthesis, secretion and action mmu04962   Vasopressin-regulated water reabsorption mmu04970   Salivary secretion mmu04971   Gastric acid secretion mmu04972   Pancreatic secretion mmu04976   Bile secretion mmu05032   Morphine addiction mmu05163   Human cytomegalovirus infection mmu05166   Human T-cell leukemia virus 1 infection mmu05200   Pathways in cancer mmu05207   Chemical carcinogenesis - receptor activation mmu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mmu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     104111 (Adcy3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     104111 (Adcy3)    04371 Apelin signaling pathway     104111 (Adcy3)    04020 Calcium signaling pathway     104111 (Adcy3)    04072 Phospholipase D signaling pathway     104111 (Adcy3)    04024 cAMP signaling pathway     104111 (Adcy3)    04022 cGMP-PKG signaling pathway     104111 (Adcy3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     104111 (Adcy3)    04081 Hormone signaling     104111 (Adcy3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     104111 (Adcy3)   09144 Cellular community - eukaryotes    04540 Gap junction     104111 (Adcy3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     104111 (Adcy3)    04062 Chemokine signaling pathway     104111 (Adcy3)   09152 Endocrine system    04911 Insulin secretion     104111 (Adcy3)    04923 Regulation of lipolysis in adipocytes     104111 (Adcy3)    04912 GnRH signaling pathway     104111 (Adcy3)    04913 Ovarian steroidogenesis     104111 (Adcy3)    04915 Estrogen signaling pathway     104111 (Adcy3)    04914 Progesterone-mediated oocyte maturation     104111 (Adcy3)    04921 Oxytocin signaling pathway     104111 (Adcy3)    04926 Relaxin signaling pathway     104111 (Adcy3)    04935 Growth hormone synthesis, secretion and action     104111 (Adcy3)    04918 Thyroid hormone synthesis     104111 (Adcy3)    04928 Parathyroid hormone synthesis, secretion and action     104111 (Adcy3)    04916 Melanogenesis     104111 (Adcy3)    04925 Aldosterone synthesis and secretion     104111 (Adcy3)    04927 Cortisol synthesis and secretion     104111 (Adcy3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     104111 (Adcy3)    04270 Vascular smooth muscle contraction     104111 (Adcy3)   09154 Digestive system    04970 Salivary secretion     104111 (Adcy3)    04971 Gastric acid secretion     104111 (Adcy3)    04972 Pancreatic secretion     104111 (Adcy3)    04976 Bile secretion     104111 (Adcy3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     104111 (Adcy3)   09156 Nervous system    04724 Glutamatergic synapse     104111 (Adcy3)    04727 GABAergic synapse     104111 (Adcy3)    04725 Cholinergic synapse     104111 (Adcy3)    04723 Retrograde endocannabinoid signaling     104111 (Adcy3)   09157 Sensory system    04740 Olfactory transduction     104111 (Adcy3)    04750 Inflammatory mediator regulation of TRP channels     104111 (Adcy3)   09149 Aging    04211 Longevity regulating pathway     104111 (Adcy3)    04213 Longevity regulating pathway - multiple species     104111 (Adcy3)   09159 Environmental adaptation    04713 Circadian entrainment     104111 (Adcy3)    04714 Thermogenesis     104111 (Adcy3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     104111 (Adcy3)    05207 Chemical carcinogenesis - receptor activation     104111 (Adcy3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     104111 (Adcy3)    05163 Human cytomegalovirus infection     104111 (Adcy3)   09165 Substance dependence    05032 Morphine addiction     104111 (Adcy3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     104111 (Adcy3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     104111 (Adcy3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     104111 (Adcy3) Enzymes [BR:mmu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      104111 (Adcy3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  104111 NCBI-ProteinID:  NP_612178 MGI:  99675 Ensembl:  ENSMUSG00000020654 UniProt:  Q8VHH7 Q80TY9 LinkDB All DBs Position 12:4183397..4263525 Genome browser AA seq 1145 aa AA seqDB search MPRNQGFSDPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLMVAGFGLVLDII LFVLCKKGLLPDRVSRKVVPYLLWLLISAQIFSYLGLNFSRAHAASDTVGWQAFFVFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDELEGMQLLREILANVFLYLCAIIVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCD YLDEKGIETYLIIASKPEVKKTAQNGLNGSAVPNGAPASSKPSSPALIETKEPNGSAHAS GSTSEEAEEQEAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQ VVKKRNTFLLTMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLFCTAMVEILIDPWLMTNY VTFVVGEVLLLILTICSMAAIFPRSFPKKLVAFSSWIDRTRWARNTWAMLAIFILVMANV VDMLSCLQYYMGPYNMTAGMELDGGCMENPKYYNYVAVLSLIATIMLVQVSHMVKLTLML LVTGAVTALNLYAWCPVFDEYDHKRFQEKDSPMVALEKMQVLATPGLNGTDSRLPLVPSK YSMTVMMFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEEKSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDRPAAFPNGSSVTLPHQ VVDNP NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaaccagggcttctcggatcccgagtactcggcagagtactcagctgaatac tcggtcagcctgccctctgaccccgaccgcggggtcggccggacccatgaaatttctgtg cggaactcggggtcctgcctgtgcctgcctcgctttatgcggctgaccttcgtgcctgag tccttggagaacctctaccagacctacttcaaaaggcagcgccatgagaccctgctggtg ctggtggtctttgcggccctctttgactgctacgtggtagtgatgtgcgcggtggtcttc tccagcgacaagctggcgcccctcatggtggcaggcttcggtctggtgttggacatcatc cttttcgtgctctgtaaaaaggggctgctcccggaccgagtgagccgcaaagtggtaccc tacctgctgtggctgctcatctcggcccagatcttctcctacctgggcctgaacttttca cgggcccacgcagccagtgacactgtgggttggcaggctttctttgtcttctccttcttc ataacgctgcccctcagcctcagccccatcgtgatcatctctgtggtctcctgtgttgtg cacacgcttgtgttgggggtcactgtggcccagcagcagcaggatgagctggaagggatg cagctgctgagggagatcctggccaacgtcttcctctacctgtgtgctatcatcgtgggc atcatgtcctactacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag tcactggaggtgaagatgaatctggaggagcagagccagcagcaggaaaaccttatgctt tccatcctgcccaagcacgtggctgacgagatgctgaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcaataccatgtacatgtaccggcacgagaatgtcagcatc ctgtttgcagatattgtgggctttacccagctgtcctctgcttgcagtgcccaggagctc gtgaagttactcaacgagctcttcgcccgctttgacaagctggcagccaaataccaccag ctgaggatcaagatcctaggcgactgttactactgcatctgcggcttgcctgactaccgg gaggaccatgccgtgtgctccatccttatggggcttgccatggtagaggccatctcgtac gtgcgggagaagaccaagactggagtggacatgcgtgtgggagtgcacacaggcactgtc ctaggcggtgtcctgggccagaagcgctggcagtatgatgtatggtctactgatgtcacc gtggcaaacaagatggaggctggtggcatcccagggcgcgtgcacatttcccagagcacc atggactgcctgaagggggagtttgatgtggagcctggtgatgggggcagtcgctgcgac tacctagatgagaagggcatcgaaacctacctcatcattgcctccaagccagaggtgaag aaaacagcccaaaatggcctcaacggctcggccgtgccaaacggagcgccggcatcctcc aaacccagctcccctgccctcatcgagaccaaggagcccaatggaagtgcccatgccagc ggctccacatcagaggaggctgaagaacaggaggcccaggctgacaacccctcgttcccc aacccccgccgcaggctgcgcctccaggacctggcggaccgtgtggtggacgcctctgag gatgagcacgaactgaaccagctgcttaatgaggccctgctggagcgggagtccgcccag gtggtaaagaagagaaacacattcctcctgaccatgaggttcatggacccagagatggaa acacgctactcggtggagaaggagaagcagagcggggctgccttcagctgctcctgtgtg gtcctcttctgcacggccatggtggagatactcattgacccctggctgatgacaaactat gtgacctttgtggttggggaggttctgctcctgatcctgaccatctgctcgatggctgcc atctttcccaggtcatttcccaagaagcttgtggccttctcatcttggattgaccggacc cgctgggcaaggaacacctgggccatgttagccatcttcattctggttatggccaatgtt gtggacatgctcagctgtctccagtactacatgggaccttacaacatgacagctgggatg gagctggacggcggctgcatggagaaccccaagtactacaactacgtagctgtgctgtcg ctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctgacgctcatgctg ctcgtcacaggcgccgtgactgccctcaacctgtacgcctggtgtcctgtctttgatgaa tacgaccacaagcgctttcaggaaaaggactctcctatggtggccttagagaagatgcag gtacttgccacccctgggctcaatggcactgacagcaggctgcccctggtgccttccaag tactccatgactgtgatgatgttcgtcatgatgctgagcttttactacttctcgcgccac gtggaaaaactggcccgaacactgttcttgtggaagattgaggtccatgaccagaaagaa cgtgtctacgagatgcgccgatggaacgaggccttggtcaccaacatgttgcctgagcat gttgcacgccattttctggggtccaagaagagagatgaggagctgtacagccagtcttat gacgagattggagtcatgtttgcctccttgcccaactttgctgacttctacactgaggag agcatcaacaacggcggcatcgagtgtctacgcttcctcaatgagatcatctctgatttt gactctctcctggacaatcccaaattccgggtcatcaccaagatcaaaactattggcagc acctatatggcagcttcaggagtcacaccagatgtcaacaccaatggctttacaagctcc agcaaggaggagaagtcagacaaggagcgctggcagcacctggctgacctggctgacttt gcattagccatgaaggacacgctcacaaacatcaacaaccagtcattcaacaacttcatg ttgcgcataggcatgaacaaaggaggggttctggctggcgtcattggagcccggaaacca cactatgacatctggggcaatacggtcaatgtggccagcaggatggaatccacaggagtc atgggcaacatccaggtggtagaagagacgcaggtcatccttcgagagtacggcttccgc tttgtgaggcgaggtcccatctttgtgaaaggcaaaggggagcttctgacctttttcttg aaggggcgggacaggccagctgccttccccaatggctcctctgttacactgccccaccaa gtggtggacaacccctga

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