Mus musculus (mouse): 11789
Entry
11789 CDS
T01002
Gene name
Apc, AI047805, AU020952, AW124434, CC1, Min, mAPC
Definition
(RefSeq) APC, WNT signaling pathway regulator
KO
K02085
adenomatosis polyposis coli protein
Organism
mmu
Mus musculus (mouse)
Pathway
mmu04310
Wnt signaling pathway
mmu04390
Hippo signaling pathway
mmu04550
Signaling pathways regulating pluripotency of stem cells
mmu04810
Regulation of actin cytoskeleton
mmu04934
Cushing syndrome
mmu05165
Human papillomavirus infection
mmu05200
Pathways in cancer
mmu05206
MicroRNAs in cancer
mmu05210
Colorectal cancer
mmu05213
Endometrial cancer
mmu05217
Basal cell carcinoma
mmu05224
Breast cancer
mmu05225
Hepatocellular carcinoma
mmu05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
11789 (Apc)
04390 Hippo signaling pathway
11789 (Apc)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
11789 (Apc)
09142 Cell motility
04810 Regulation of actin cytoskeleton
11789 (Apc)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
11789 (Apc)
05206 MicroRNAs in cancer
11789 (Apc)
09162 Cancer: specific types
05210 Colorectal cancer
11789 (Apc)
05225 Hepatocellular carcinoma
11789 (Apc)
05226 Gastric cancer
11789 (Apc)
05217 Basal cell carcinoma
11789 (Apc)
05213 Endometrial cancer
11789 (Apc)
05224 Breast cancer
11789 (Apc)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
11789 (Apc)
09172 Infectious disease: viral
05165 Human papillomavirus infection
11789 (Apc)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mmu01009
]
11789 (Apc)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmu03036
]
11789 (Apc)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
mmu04812
]
11789 (Apc)
Protein phosphatases and associated proteins [BR:
mmu01009
]
Protein Ser/ Thr phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
11789 (Apc)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic Type
Centrosome formation and ciliogenesis proteins
Other centriole associated proteins
11789 (Apc)
Cytoskeleton proteins [BR:
mmu04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
11789 (Apc)
SSDB
Motif
Pfam:
Arm_APC_u3
APC_basic
EB1_binding
APC_r
APC_u5
APC_rep
APC_u14
APC_u15
APC_u9
SAMP
Arm
APC_u13
APC_15aa
Suppressor_APC
Other DBs
NCBI-GeneID:
11789
NCBI-ProteinID:
NP_001347908
MGI:
88039
Ensembl:
ENSMUSG00000005871
Vega:
OTTMUSG00000035932
LinkDB
Position
18 B1; 18 18.53 cM
AA seq
2783 aa
MTSGQIDLLERLKEFNLDSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPRR
TFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQ
TDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRVRQLLQSQAAE
AERSSQSRHDAASHEAGRQHEGHGVAESNTAASSSGQSPATRVDHETASVLSSSGTHSAP
RRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLLH
GNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCW
EWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQV
DCEMYGLTNDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQ
QVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTE
NKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNC
LQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMG
SAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSP
KASHRSKQRHKQNLYGDYAFDANRHDDSRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSL
DSSRSEKDRSLERERGIGLSAYHPTTENAGTSSKRGLQITTTAAQIAKVMEEVSAIHTSQ
DDRSSASTTEFHCVADDRSAARRSSASHTHSNTYNFTKSENSNRTCSMPYAKVEYKRSSN
DSLNSVTSSDGYGKRGQMKPSVESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGEL
DTPINYSLKYSDEQLNSGRQSPSQNERWARPKHVIEDEIKQNEQRQARSQNTSYPVYSEN
TDDKHLKFQPHFGQQECVSPYRSRGTSGSETNRMGSSHAINQNVNQSLCQEDDYEDDKPT
NYSERYSEEEQHEEEEERPTNYSIKYNEEKHHVDQPIDYSLKYATDISSSQKPSFSFSKN
SSAQSTKPEHLSPSSENTAVPPSNAKRQNQLRPSSAQRNGQTQKGTTCKVPSINQETIQT
YCVEDTPICFSRCSSLSSLSSADDEIGCDQTTQEADSANTLQTAEVKENDVTRSAEDPAT
EVPAVSQNARAKPSRLQASGLSSESTRHNKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET
PLVFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP
PPPQTVQAKREVPKSKVPAAEKRESGPKQTAVNAAVQRVQVLPDVDTLLHFATESTPDGF
SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPEESNENQDKEVEKPDSEK
DLLDDSDDDDIEILEECIISAMPTKSSRKAKKLAQTASKLPPPVARKPSQLPVYKLLPAQ
NRLQAQKHVSFTPGDDVPRVYCVEGTPINFSTATSLSDLTIESPPNELATGDGVRAGIQS
GEFEKRDTIPTEGRSTDDAQRGKISSIVTPDLDDNKAEEGDILAECINSAMPKGKSHKPF
RVKKIMDQVQQASSTSSGANKNQVDTKKKKPTSPVKPMPQNTEYRTRVRKNTDSKVNVNT
EETFSDNKDSKKPSLQTNAKAFNEKLPNNEDRVRGSFALDSPHHYTPIEGTPYCFSRNDS
LSSLDFDDDDVDLSREKAELRKGKESKDSEAKVTCRPEPNSSQQAASKSQASIKHPANRA
QSKPVLQKQPTFPQSSKDGPDRGAATDEKLQNFAIENTPVCFSRNSSLSSLSDIDQENNN
NKESEPIKEAEPANSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ
ECISSAMPKKKRPSRLKSESEKQSPRKVGGILAEDLTLDLKDLQRPDSEHAFSPDSENFD
WKAIQEGANSIVSSLHQAAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPF
TSNKGPRILKPGEKSTLEAKKIESENKGIKGGKKVYKSLITGKIRSNSEISSQMKQPLPT
NMPSISRGRTMIHIPGLRNSSSSTSPVSKKGPPLKTPASKSPSEGPGATTSPRGTKPAGK
SELSPITRQTSQISGSNKGSSRSGSRDSTPSRPTQQPLSRPMQSPGRNSISPGRNGISPP
NKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQLSQQNLTKQASLSKNASSIPRSESASK
GLNQMSNGNGSNKKVELSRMSSTKSSGSESDRSERPALVRQSTFIKEAPSPTLRRKLEES
ASFESLSPSSRPDSPTRSQAQTPVLSPSLPDMSLSTHPSVQAGGWRKLPPNLSPTIEYND
GRPTKRHDIARSHSESPSRLPINRAGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSE
SSEKAKSEDERHVSSMPAPRQMKENQVPTKGTWRKIKESDISPTGMASQSASSGAASGAE
SKPLIYQMAPPVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGSSSIKDSKD
THGKQSVGSGSPVQTVGLETRLNSFVQVEAPEQKGTEAKPGQSNPVSIAETAETCIAERT
PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVSTNTKKRDSKT
DSTESSGAQSPKRHSGSYLVTSV
NT seq
8352 nt
+upstream
nt +downstream
nt
atgacttctggacagattgacttactagagcgtcttaaagaatttaacttagatagtaat
ttccccggagtgaaactacgctcaaaaatgtcccttcgctcctacggaagtcgggaagga
tctgtatccagccgttcaggagaatgcagtcctgtccccatggggtcattcccaagaaga
acatttgtaaatggaagcagagagagtactgggtatctagaagagcttgaaaaagaaaga
tcattactccttgctgatcttgacaaagaagagaaggaaaaggactggtattatgctcaa
cttcagaacctcacaaaaagaatagatagcctgcctttaactgaaaatttttccttacag
acagacatgacaagacggcagctggagtatgaagcaaggcagatcagggctgcaatggag
gagcagcttggcacctgccaggacatggagaagcgtgcacagcgaagaatagccaggatc
cagcaaatagaaaaggacatactgcgcgtgcgccagcttttacagtcccaggcggcggaa
gcggagaggtcatctcagagcaggcatgatgctgcctcccatgaagctggccggcagcac
gaaggccacggagtggcagaaagcaacaccgcagcctccagtagtggtcagagtccagct
acacgtgtggatcacgaaacagccagtgttttgagttctagcggcacgcactctgctcct
cgaaggttgacaagtcatctggggacaaaggtggaaatggtgtattccttgttgtcaatg
cttggtactcatgataaggacgatatgtcacgaactttgctagctatgtccagctcccaa
gacagctgtatatccatgcggcagtctggatgtcttcctctcctcatccagcttttacat
ggcaatgacaaagactctgtattgttgggaaattcccggggcagtaaagaggctcgggcc
agggccagtgcagcactccacaacatcattcactcacagcctgatgacaagagaggcagg
cgtgaaatccgagtccttcatcttttggaacagatacgagcttactgtgaaacctgttgg
gagtggcaggaagcccacgaacaaggcatggaccaggacaaaaacccaatgccagctcct
gttgagcatcagatctgtcctgctgtgtgtgttctaatgaagctttcatttgatgaagag
cataggcatgcaatgaatgaacttgggggactgcaggccattgcagagttattgcaggtg
gactgtgagatgtatgggcttactaatgaccactacagtgttactttaagacggtatgct
ggaatggctttgacaaacttgacctttggagatgttgccaacaaggctacgctgtgttct
atgaaaggctgcatgagagcacttgtggcccagttaaaatctgagagtgaagacttacag
caggttattgcaagtgttttgaggaatttgtcttggcgagcagatgtaaatagcaaaaag
acgttgagagaagttggaagtgtgaaagcattgatggaatgtgctttggaagttaaaaag
gaatcaaccctcaaaagcgttttgagtgccttatggaacctgtctgcacactgcactgag
aataaggctgacatctgtgctgtggatggagcactggcatttctggttggcaccctcact
taccggagccagacaaatactttagccattattgaaagtggaggtgggatattacggaat
gtgtccagcttgatagctacaaacgaagaccacaggcaaatcctaagagagaacaattgc
ctacaaactttattacagcacttgaaatctcacagcttgacaatagtcagtaatgcatgt
ggaactttgtggaatctctcagcaagaaatcctaaagaccaggaagccttgtgggacatg
ggggcagtgagcatgctcaagaacctcattcattccaagcacaaaatgattgccatggga
agtgcagcagctttaaggaatctcatggcaaacagacctgcaaagtataaggatgccaat
atcatgtctcccggctcaagtctgccatcccttcacgttaggaaacagaaagctctagaa
gctgagctagatgctcagcatttatcagaaaccttcgacaacattgacaacctaagtccc
aaggcctctcaccggagtaagcagagacacaagcagaatctttatggtgactatgctttt
gacgccaatcgacatgatgatagtaggtcagacaatttcaatactggaaacatgactgtt
ctttcaccatatttaaatactacggtattgcccagctcttcttcctcaaggggaagttta
gacagttctcgttctgagaaagacagaagtttggagagagagcgaggtattggcctcagt
gcttaccatccaacaacagaaaatgcaggaacctcatcaaaacgaggtctgcagatcact
accactgcagcccagatagccaaagttatggaagaagtatcagccattcatacctcccag
gacgacagaagttctgcttctaccaccgagttccattgtgtggcagacgacaggagtgcg
gcacgaagaagctctgcctcccacacacactcaaacacatacaacttcactaagtcggaa
aattcaaataggacatgctctatgccttatgccaaagtggaatataaacgatcttcaaat
gacagtttaaatagtgtcactagtagtgatggatatggtaaaagaggccaaatgaaaccc
tcagttgaatcctattctgaagatgatgaaagtaaattttgcagttatggtcagtatcca
gctgacctagcccataagatacacagtgcaaatcatatggatgataatgatggagaactg
gatacaccaataaattacagtcttaaatattcagatgagcagttgaactcaggaaggcag
agtccctcacagaatgaaaggtgggcaagaccaaagcatgtgatagaagatgaaataaag
caaaacgagcaaagacaagcaagaagccagaacaccagttatcctgtctattctgagaat
accgatgacaaacacctcaaattccaaccacattttggacaacaagaatgtgtttcccca
tataggtcaaggggaaccagtggttcagaaacaaatcgaatgggttctagtcatgcaatt
aatcaaaatgtaaaccagtctctgtgtcaggaagatgattatgaagatgataaacctacc
aactacagtgaacgttattctgaggaagaacaacatgaagaagaagaagagagaccgaca
aattatagcataaaatataatgaagagaaacatcatgtggatcagcctattgattatagt
ttaaaatatgccactgacatttcttcctcacaaaaaccatcattttcattctcaaagaat
tcatcagcacaaagcactaaacctgaacatctctctccaagcagcgagaatacagctgta
cctccatctaatgccaaaaggcagaatcagctgcgtccaagttcagcacaaagaaatggc
cagactcaaaaaggcactacttgcaaagtcccctccatcaaccaagaaacaatacagact
tactgcgtagaagacaccccaatatgtttttcaaggtgcagttcattatcatcactgtca
tcagctgacgatgaaataggatgtgatcagacaacacaggaagcagattctgctaatact
ctgcagacagcagaagtaaaagagaatgatgtaactcggtcagctgaagatcctgcaact
gaagttccagcagtgtcccagaatgctagagccaaacccagccgactccaggcttctggc
ttatcttcagaatcaaccaggcataataaagctgttgagttttcttcaggagccaagtct
ccctccaaaagtggtgctcagacacccaaaagtcccccagaacactatgtccaggagact
ccgctcgtattcagcaggtgtacttctgtcagctcccttgacagttttgagagtcgctcc
attgccagctctgttcagagtgagccatgtagtggaatggtgagtggcatcataagcccc
agtgaccttccagatagtcctgggcagaccatgccaccaagcagaagcaaaacccctcca
cctcctccacagacagtgcaggccaagagagaggtgccaaaaagtaaagtccctgctgct
gagaagagagagagtgggcctaagcagactgctgtaaatgctgccgtgcagagggtgcag
gtccttccagacgtggatactttgttacacttcgccacagaaagtactccagacgggttt
tcttgttcctccagcctaagtgctctgagcctggatgagccatttatacagaaagatgta
gaattaagaatcatgcctccagttcaggaaaacgacaatgggaatgaaactgaatcagaa
cagcctgaggaatcaaatgaaaaccaggataaagaggtagaaaagcctgactctgaaaaa
gacttattagatgattctgatgacgatgatattgaaatattagaagaatgtattatttca
gccatgccaacaaagtcatcacgcaaagccaaaaaactagcccagactgcttcaaaatta
cctccacctgtggcaaggaaaccaagtcagctacctgtgtataaacttctgccagcacag
aataggctgcaggcacaaaaacatgttagctttacaccaggggatgatgtgccccgggtg
tactgtgtagaagggacacctataaacttttccacagcaacgtctctaagtgatctgaca
atagagtcccctccaaatgaattggctactggagatggggtcagagcgggtatacagtca
ggtgaatttgaaaaacgagataccattcctacagaaggcagaagtacagatgatgctcag
cgaggaaaaatctcatctatagttacaccagacctggatgacaacaaagcagaggaagga
gatattcttgcagaatgtatcaattctgctatgcccaaaggaaaaagccacaagcctttc
cgagtgaaaaagataatggaccaagtccaacaagcatcctcgacttcatctggagctaac
aaaaatcaagtagacactaagaaaaagaagcctacttcaccagtaaagcccatgccacaa
aatactgaatatagaacgcgtgtgagaaagaatacagactcaaaagttaatgtaaatact
gaagaaactttctcagacaacaaagactcaaagaaaccaagcttacaaaccaatgccaag
gccttcaatgaaaagctacctaacaatgaagacagagtgcgggggagcttcgccttggac
tcaccgcatcactacacccctattgaggggacgccgtactgcttttcccgaaatgactcc
ttgagttctctggattttgatgatgacgatgttgacctttccagggaaaaggccgagtta
agaaagggcaaagaaagcaaggattccgaagccaaagttacctgccgcccagaaccaaac
tcaagccagcaggcagctagtaagtcacaagccagtataaaacatccagcaaacagagca
cagtccaaaccagtgctgcagaaacagcccactttcccccagtcctccaaagacggacca
gatagaggggcagcaactgacgaaaaactgcagaattttgctattgaaaatactccagtt
tgcttttctcgaaattcctctctgagttcccttagtgacattgaccaggaaaacaacaat
aacaaagaaagtgaaccaatcaaagaagctgaacctgccaactcacaaggagagcccagt
aagcctcaggcatccgggtatgctcccaagtccttccacgtcgaagacacccctgtctgt
ttctcaagaaacagctctctcagttctcttagcattgactctgaggacgacctgttacag
gagtgtataagttctgccatgccaaaaaagaaaaggccttcaagactcaagagtgagagc
gaaaagcagagccctagaaaagtgggtggcatattagctgaagacctgacgcttgatttg
aaagatctacagaggccagattcagaacacgctttctcccccgactcagaaaattttgac
tggaaagctattcaggaaggcgcaaactccatagtaagtagtttgcaccaagctgctgca
gccgccgcgtgcttatctagacaagcgtcatccgactcagattccattctgtcactaaag
tccggcatttctctgggatcgccttttcatcttacacctgatcaagaggaaaagccattc
acaagcaataaaggcccaagaattctcaaacctggagagaaaagcacattagaagcaaaa
aaaatagaatctgaaaacaaaggaatcaaaggcgggaaaaaggtttataaaagcttgatt
acgggaaagattcgctccaattcagaaatttccagccaaatgaaacaacccctcccgaca
aacatgccttcaatctcaagaggcaggacgatgattcacatcccagggcttcggaatagc
tcctctagtacaagccctgtctctaagaaaggcccacccctcaagactccagcctctaaa
agccccagtgaagggccgggagctaccacttctcctcgaggaactaagccagcaggaaag
tcagagcttagccctatcaccaggcaaacttcccaaatcagtgggtcaaataaggggtct
tctagatcaggatctagagactccactccctcaagacctacacagcaaccattaagtagg
ccaatgcagtctccagggcgaaactcaatttcccctggtagaaatggaataagccctcct
aacaaactgtctcagctgcccagaacatcatctcccagtactgcttcaactaagtcctcc
ggttctgggaaaatgtcatatacatccccaggtagacagctgagccaacaaaatcttacc
aaacaagcaagtttatccaagaatgccagcagtatccccagaagtgagtcggcatctaaa
ggactgaatcagatgagtaacggcaatgggtcaaataaaaaggtagaactttctagaatg
tcttcaactaaatcaagtggaagtgaatcagacagatcagaaaggcctgcattagtacgc
cagtctactttcatcaaagaagccccaagcccaaccctgaggaggaaactggaggaatct
gcctcatttgaatccctttctccatcttctagaccagattctcccaccaggtcgcaggca
cagaccccagttttaagcccttcccttcctgatatgtctctgtccacacatccatctgtt
caggcaggtgggtggcgaaagctcccgcctaatctcagccccactatcgagtataatgac
ggaaggcccacaaaacggcatgatattgcacgctcccattctgaaagtccttccagacta
ccaatcaaccgggcgggaacctggaagcgtgaacacagcaaacattcctcgtcccttcct
cgagtgagtacttggagaagaactggaagctcatcttctattctttctgcttcatcagag
tccagtgaaaaagcaaaaagtgaggatgaaaggcatgtgagctccatgccagcacccaga
cagatgaaggaaaaccaggtgcccaccaaaggaacatggaggaaaatcaaggaaagtgac
atttctcccacaggcatggcttctcagagcgcttcctcaggtgctgccagtggtgctgaa
tccaagcctctgatctatcagatggcacctcctgtctctaaaacagaggatgtttgggtg
agaattgaggactgccccattaacaaccctagatctggacggtcccccacaggcaacacc
cccccagtgattgacagtgtttcagagaagggaagttcaagcattaaagattcaaaagac
acccatgggaaacagagtgtgggcagtggcagtcctgtgcaaaccgtgggtctggaaacc
cgcctcaactcctttgttcaggtagaggccccagaacagaaaggaactgaggcaaaacca
ggacagagtaacccagtctctatagcagagactgctgagacgtgtatagcagagcgtacc
cctttcagttccagtagctccagcaagcacagctcacctagcgggactgttgctgccaga
gtgacaccttttaattacaaccctagccctaggaagagcagcgcagacagcacttcagcc
cggccgtctcagatccctacgccagtgagcaccaacacgaagaagagagattcgaagact
gacagcacagaatccagtggagcccaaagtcctaaacgccattccgggtcttacctcgtg
acgtctgtttaa
Mus musculus (mouse): 23805
Entry
23805 CDS
T01002
Gene name
Apc2, AI852447, APCL, R75424
Definition
(RefSeq) adenomatosis polyposis coli 2
KO
K02085
adenomatosis polyposis coli protein
Organism
mmu
Mus musculus (mouse)
Pathway
mmu04310
Wnt signaling pathway
mmu04390
Hippo signaling pathway
mmu04550
Signaling pathways regulating pluripotency of stem cells
mmu04810
Regulation of actin cytoskeleton
mmu04934
Cushing syndrome
mmu05165
Human papillomavirus infection
mmu05200
Pathways in cancer
mmu05206
MicroRNAs in cancer
mmu05210
Colorectal cancer
mmu05213
Endometrial cancer
mmu05217
Basal cell carcinoma
mmu05224
Breast cancer
mmu05225
Hepatocellular carcinoma
mmu05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
23805 (Apc2)
04390 Hippo signaling pathway
23805 (Apc2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
23805 (Apc2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
23805 (Apc2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
23805 (Apc2)
05206 MicroRNAs in cancer
23805 (Apc2)
09162 Cancer: specific types
05210 Colorectal cancer
23805 (Apc2)
05225 Hepatocellular carcinoma
23805 (Apc2)
05226 Gastric cancer
23805 (Apc2)
05217 Basal cell carcinoma
23805 (Apc2)
05213 Endometrial cancer
23805 (Apc2)
05224 Breast cancer
23805 (Apc2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
23805 (Apc2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
23805 (Apc2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mmu01009
]
23805 (Apc2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmu03036
]
23805 (Apc2)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
mmu04812
]
23805 (Apc2)
Protein phosphatases and associated proteins [BR:
mmu01009
]
Protein Ser/ Thr phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
23805 (Apc2)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic Type
Centrosome formation and ciliogenesis proteins
Other centriole associated proteins
23805 (Apc2)
Cytoskeleton proteins [BR:
mmu04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
23805 (Apc2)
SSDB
Motif
Pfam:
APC_basic
APC_rep
APC_N_CC
APC_r
Suppressor_APC
Arm_APC_u3
Arm
SAMP
bZIP_1
HALZ
HMMR_C
Other DBs
NCBI-GeneID:
23805
NCBI-ProteinID:
NP_035919
MGI:
1346052
Ensembl:
ENSMUSG00000020135
Vega:
OTTMUSG00000000013
UniProt:
G5E832
LinkDB
Position
10; 10 C1
AA seq
2274 aa
MTSSMASYEQLVRQVEALKAENTHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKLEQE
ARVLVSSGQTEVLEQLKALQTDISSLYNLKFHAPALGPEPAARTPEGSPVHGSGPSKDSF
GELSRATIRLLEELDQERCFLLSEIEKEEKEKLWYYSQLQGLSKRLDELPHVDTFSMQMD
LIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDKELLEAQDRVQQTEPQAL
LAVKPVAVEEEQEAEVPTHPEDGTPQPGNSKVEVVFWLLSMLATRDQEDTARTLLAMSSS
PESCVAMRRSGCLPLLLQILHGTEAGSVGRAGIPGAPGAKDARMRANAALHNIVFSQPDQ
GLARKEMRVLHVLEQIRAYCETCWDWLQARDSGTETPVPIEPQICQATCAVMKLSFDEEY
RRAMNELGGLQAVAELLQVDYEMHKMTRDPLNLALRRYAGMTLTNLTFGDVANKATLCAR
RGCMEAIVAQLGSESEELHQVVSSILRNLSWRADINSKKVLREVGSMTALMECVLRASKE
STLKSVLSALWNLSAHSTENKAAICQVDGALGFLVSTLTYRCQGNSLAVIESGGGILRNV
SSLIATREDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSPRDQELLWDLG
AVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPAKYQAAAMAVSPGTCVPSLYVRKQRALE
AELDTRHLVHALGHLEKQSLPEAETTSKKPLPPLRHLDGLVQDYASDSGCFDDDDAPSLA
AAATTAEPASPAVMSMFLGGPFLQGQALARTPPARQGGLEAEKEAGGEAAVAAKAKAKLA
LAVARIDRLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRGTEGGRREAGSR
AHPLLRLKAAHTSLSNDSLNSGSTSDGYCTREHMTPCPLAALAEHRDDPVRGQTRPSRLD
LDLPSRAELPARDTAATDARVRTIKLSPTYQHVPLLDGAAGAGVRPLVGPGTSPGARKQA
WIPADSLSKVPEKLVASPLPIASKVLQKLVAQDGPMSLSRCSSLSSLSSTGHAVPSQAEN
LDSDSSLEGLEEAGPGEAELGRAWRASGSTSLPVSIPAPQRGRSRGLGVEDATPSSSSEN
CVQETPLVLSRCSSVSSLGSFESRSIASSIPSDPCSGLGSGTVSPSELPDSPGQTMPPSR
SKTPPAPPGQPETSQFSLQWESYVKRFLDIADCRERCQPPSELDAGSVRFTVEKPDENFS
CASSLSALALHELYVQQDVELRLRPPACPERAVGGGGHRRRDEAASRLDGPAPAGSRARS
ATDKELEALRECLGAAMPARLRKVASALVPGRRSLPVPVYMLVPAPARGDDSGTDSAEGT
PVNFSSAASLSDETLQGPSRDKPAGPGDRQKPTGRAAPARQTRSHRPKAAGAGKSTEHTR
GPCRNRAGLELPLSRPQSARSNRDSSCQTRTRGDGALQSLCLTTPTEEAVYCFYDSDEEP
PATAPPPRRASAIPRALKREKPAGRKETPSRAAQPATLPVRAQPRLIVDETPPCYSLTSS
ASSLSEPEAPEQPANHARGPEQGSKQDSSPSPRAEEELLQRCISLAMPRRRTQVPGSRRR
KPRALRSDIRPTEITQKCQEEVAGSDPASDLDSVEWQAIQEGANSIVTWLHQAAAKASLE
ASSESDSLLSLVSGVSAGSTLQPSKLRKGRKPAAEAGGAWRPEKRGTTSTKINGSPRLPN
GPEKAKGTQKMMAGESTMLRGRTVIYSAGPASRTQSKGISGPCTTPKKTGTSGTTQPETV
TKAPSPEQQRSRSLHRPGKISELAALRHPPRSATPPARLAKTPSSSSSQTSPASQPLPRR
SPLATPTGGPLPGPGGSLVPKSPARALLAKQHKTQKSPVRIPFMQRPARRVPPPLARPSP
EPGSRGRAGAEGTPGARGSRLGLVRMASARSSGSESSDRSGFRRQLTFIKESPGLLRRRR
SELSSADSTASTSQAASPRRGRPALPAVFLCSSRCDELRVSPRQPLAAQRSPQAKPGLAP
RAPRRTSSESPSRLPVRASPGRPETVKRYASLPHISVSRRSDSAVSVPTTQANATRRGSD
GEARPLPRVAPPGTTWRRIKDEDVPHILRSTLPATALPLRVSSPEDSPAGTPQRKTSDAV
VQTEDVATSKTNSSTSPSLESRDPPQAPASGPVAPQGSDVDGPVLTKPPASAPFPHEGLS
AVIAGFPTSRHGSPSRAARVPPFNYVPSPMAAATMASDSAVEKAPVSSPASLLE
NT seq
6825 nt
+upstream
nt +downstream
nt
atgaccagctccatggcctcatatgagcagctggtgcgccaggtggaggccctgaaggcc
gagaacactcacttaaggcaggagctgagggataactctagccatctctccaagcttgag
acagagacttctggaatgaaggaggtcctgaaacacctccagggcaagctggagcaggag
gcgagagtgctcgtgtcttccgggcagacagaagtgttagagcaactgaaagctcttcag
actgacatcagtagcctgtacaacctcaagtttcatgctccagccctgggcccggagcct
gccgcccggactccagagggaagcccagtgcacggctctggaccatccaaggacagcttt
ggagagctgagccgggccaccatccgcctgctggaagaactggaccaggagagatgcttc
ctgctgagcgagatagagaaagaggagaaggagaagctatggtattactctcagctccag
ggcctgtccaagcgcttggatgagctgccgcacgtggacacgttttcgatgcagatggat
ctgattcggcagcagctggagttcgaggcccagcacatccgctcgctgatggaggagcgc
ttcggtacctccgacgagatggtgcagcgggcgcagatccgggcttcgcgcttggagcag
attgacaaggagctgttggaagcccaggaccgggtgcagcagacagagcctcaggctctg
ctggcggtgaagcctgtggcagtagaggaggagcaggaggcagaagtccccacacatcct
gaggatggcacccctcagcctggcaacagcaaggtggaggtggtgttctggcttctatct
atgttggcaacgcgcgaccaggaagatactgcgcgcacactgctggccatgtccagctct
ccagagagctgtgtagccatgcgccgctcgggctgtctgccactgctgctccagatcctt
catggcactgaggctgggtctgtggggcgcgcagggatccccggagcgcctggtgccaaa
gatgcacgcatgcgcgccaatgcggccctgcacaacatcgttttctcccagccggatcag
ggcctggcacgcaaggagatgcgtgtgctgcatgtgctggagcagatccgagcctactgc
gagacctgctgggactggcttcaggcgcgggacagcgggacagaaactcctgtcccaatc
gagccgcagatctgccaggctacctgtgcagtgatgaagctgtcatttgacgaagaatac
cgtcgggctatgaatgagctaggggggctgcaggctgtggcagaactactgcaggtggac
tatgaaatgcacaagatgacccgggacccactcaaccttgccctgcgccgctacgctggc
atgaccctcaccaacctcacctttggagacgttgccaacaaggccacactgtgtgcccgc
cgaggctgcatggaagccattgtggcccagcttggctctgagagcgaggagctgcatcag
gttgtttccagtattctgcgtaatctgtcatggagggcagacatcaacagcaagaaggtg
ctgagggaggttggcagcatgaccgccttgatggaatgtgtgctgcgggcctccaaggag
tcgaccctaaagagtgtgctcagtgctctgtggaacctgtcagcacacagcacagagaac
aaggcagccatctgccaggtagatggtgcactgggtttcctggtgagcaccctcacatac
cgttgccaagggaactccctggcagtcatcgagagtggcggtgggatcctgcgcaacgtg
tcaagcctcattgccacacgggaggactacaggcaggtgctccgtgaccacaactgcctg
cagacactgctgcagcacctcacatcacacagtttgaccatcgtgagcaatgcctgtggc
accctctggaacctgtctgcccgcagcccccgcgatcaggaactgttgtgggacctgggg
gccgtgggcatgctacgcaacctcgtccactccaaacacaagatgatcgccatgggtagt
gctgctgctctgcggaacctgctagcccaccgacccgccaagtatcaggccgcagccatg
gctgtctccccaggcacctgcgtgcccagtctttacgtccgcaagcagagggctctggaa
gctgagttggacactcggcacctggtgcatgcactcggtcacttagagaagcagagtctg
cctgaggcagagaccacttcaaagaagcccctgccacccctccgccacctggacgggctg
gtgcaggactatgcctctgattctggctgctttgacgatgatgatgcaccatccctggct
gctgctgccaccacagctgagcccgccagcccagcagtgatgtctatgttccttggcggt
cccttccttcagggccaggcactggcccgcaccccacctgcccgccagggtggcctagaa
gccgagaaggaggctggtggggaggcagctgtggctgccaaggccaaggccaagctggcg
ttggctgtggctcggatcgacagattggtggaggacatctctgccctgcacacctcatca
gacgacagcttcagtctcagctcgggggaccctgggcaggaggcgccaagggagggccgt
gctcagtcctgctctccatgccggggcactgagggtgggaggcgtgaggctggcagccgg
gcgcaccctcttttgaggctcaaggcagcccacactagcctctctaatgatagcttgaac
agcggtagcaccagcgatggctactgtacccgggaacacatgacgccttgcccgctggct
gcactggccgagcaccgtgatgaccctgtgcgcggacagactcggcccagccgactggac
ctggaccttcccagccgggctgagcttcctgcccgggacacagcagccaccgatgcccga
gtgcgcacaatcaagttatccccaacctatcagcatgttccactgctggatggggccgct
ggggcaggtgttcgacccctggttgggccgggaacctccccgggggctcggaaacaggca
tggatacctgcagacagcctgagcaaagtccctgagaaactggtggcctctccactgccc
atagctagcaaggtgctgcagaagctggtcgcacaggatgggccgatgtccctctccagg
tgcagctctctgtcctctctatcttccacgggccatgctgtccccagccaggcagagaac
cttgacagcgattcatccctggaggggcttgaggaggctggtcctggtgaggccgagctg
ggcagggcgtggcgagcatccgggtccacctctcttccggtgtccatcccagccccgcag
cgggggcgcagtagaggtcttggggtggaggatgcaacaccatccagctcatctgagaac
tgcgtccaggagacgcctttggtcctgagccgttgtagttccgtgagctccctgggcagc
ttcgagagccgctccattgccagctccatccccagtgacccgtgcagcgggctgggcagt
ggcacagtgagtcccagcgagctgccagacagccccgggcagacgatgccaccgagccgc
agcaagacgccaccggcacctcctgggcagcctgagaccagccagttcagcctgcagtgg
gaaagctatgtgaagcgcttcctagacatcgcagactgtcgagaaagatgccagccgccc
tcggagctggacgcgggcagcgttcgcttcacagtggagaagccagatgagaatttctcc
tgcgcctccagcctcagtgcactggcccttcatgagctgtatgtccagcaggatgtggag
ctgcgtctgaggccacctgcctgcccagagcgtgcggtgggtggtgggggccaccgtcgg
agggacgaggctgccagccgcctggatggtccagcaccagctggttctagggctcggtca
gcaactgataaagaactggaggctttgcgtgaatgcctgggggcagccatgcccgcccgg
ctccgcaaggtggcctcggccttggtgcctggccgccgctcattgccagtccctgtgtac
atgttagtgcccgccccggctcggggtgatgactcgggcacggactccgcagagggcaca
cccgttaacttttccagtgcagcctcgctcagtgacgagaccttacagggaccctccagg
gacaagccagccgggcctggggacaggcagaaacctacaggccgagctgcccctgccagg
cagacccgatctcaccggcccaaagcagcaggcgctggtaagagcacagaacacacccgg
gggccctgtaggaaccgggcaggattggagctaccactcagcaggccccagagtgctcgg
tccaacagggatagctcatgccagacccggacccgcggagatggtgccctgcagtcgcta
tgcctcacaacacccacagaggaagctgtgtactgcttctatgactctgatgaggaacca
ccagccactgcaccaccacctcggcgggcatccgccatcccacgggctctaaagcgcgag
aaaccggcaggcagaaaggagactccatccagggcagcccagcctgccacactccctgtg
agagcccaacccagactgatcgtggatgagaccccgccctgctattccctgacttcctca
gctagttccctcagtgagcctgaggcccctgaacagccggccaaccatgctcgaggcccg
gagcagggtagtaaacaggacagctctcctagcccaagggcagaagaggaacttctgcag
agatgtatcagcttggccatgcccaggcgccggacccaggtgcctggctcacggcgtcgc
aagcccagagccttgaggtcagacataaggcccactgagataacccagaaatgccaggag
gaggtggctggctccgatccagcctctgacctagacagtgtggagtggcaggctatccaa
gagggcgcaaactccattgtcacatggctgcatcaggcagcggccaaagccagcctggaa
gcatcttctgagtctgactccctcttgtctttggtgtccggggtgtcagcaggctccacc
ctccagccctccaagctcaggaaagggcgaaagcctgcagcagaggctggaggtgcctgg
cgtcctgagaaacggggcacaacttccactaagatcaatgggagtccccggctacctaac
ggtcctgagaaggcaaagggtacccagaaaatgatggcaggggagtcaaccatgctccgg
ggacggacagtgatctactcagccggcccagcctcccgcactcagtccaaaggtatttct
ggaccttgtaccacacctaagaagacagggacatctggtaccactcagccagaaactgtc
accaaagcccccagccctgagcaacaacgttcacggagcctccaccgaccgggcaagatc
tctgagctggcagctttgcgccacccgcccaggagtgccactcctccagcccgcctcgcc
aagaccccgtcctcaagctcttcacagacctctccagcatcccagcccctgcctaggcgg
tcccctctggccactcccacaggaggacctctgcctggccctggggggtccctggtgccc
aagtcaccagcacgggcccttctggctaagcaacacaagacccagaagtcacctgtgcgg
atcccattcatgcaaaggccagccaggcgagtgccacctccactggccaggccatcccca
gaacctggctctaggggccgagctggggctgagggtactcctggggcacgtggcagccgc
ctgggcctggtgcgtatggcttcagctcgctccagtggcagcgagtcctcggatcgctca
ggcttccgaagacagctgactttcatcaaggaatccccaggtctccttcggcgtcgcaga
tcagagctgtcctctgcggactccacggcctccacctcccaggctgcttcgccccgccgt
ggacggcctgcactccctgctgtctttctctgctcctctcgttgcgatgagctgcgggta
tccccacggcagcccctggcagcacagaggtccccacaggccaagccaggtctcgcccca
cgtgcgcccagacgcaccagctctgagagcccctcacgcctgcctgtgcgggcgagccct
ggacggcctgagacagtcaagcggtacgcatccctgccacatattagtgtgtcccgcagg
tccgatagcgctgtctctgtgcccaccacccaggccaatgccactcgccggggaagtgat
ggcgaggccaggccgctgcccagggtagctcctccgggtacgacctggcgtcgaatcaaa
gatgaagatgtcccccacatcctgcgcagcacactgcctgccactgccctgcctctcagg
gtctcgtcacccgaagacagccccgctggaactccacagcgcaagaccagtgacgcagtg
gtgcaaacagaggacgtggccacttctaagaccaactctagcacgtcacctagcctggag
agcagggatccgccacaggcccctgccagcggccctgtggctccccagggcagcgatgtg
gatggaccagtactcaccaagcctcctgcctcagcgcccttcccccatgagggtctgagt
gctgtcatagcaggctttcccaccagcaggcatggctcccccagcagggctgcacgggtt
ccccccttcaactatgtgcccagccctatggcagcggccacaatggccagtgactccgca
gtggagaaagccccggtctcctctccagccagtctcctggagtag
DBGET
integrated database retrieval system
