KEGG   Mustela nigripes (black-footed ferret): 132019083
Entry
132019083         CDS       T09425                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mnp  Mustela nigripes (black-footed ferret)
Pathway
mnp01522  Endocrine resistance
mnp04010  MAPK signaling pathway
mnp04015  Rap1 signaling pathway
mnp04068  FoxO signaling pathway
mnp04071  Sphingolipid signaling pathway
mnp04114  Oocyte meiosis
mnp04148  Efferocytosis
mnp04218  Cellular senescence
mnp04261  Adrenergic signaling in cardiomyocytes
mnp04370  VEGF signaling pathway
mnp04380  Osteoclast differentiation
mnp04550  Signaling pathways regulating pluripotency of stem cells
mnp04611  Platelet activation
mnp04613  Neutrophil extracellular trap formation
mnp04620  Toll-like receptor signaling pathway
mnp04621  NOD-like receptor signaling pathway
mnp04622  RIG-I-like receptor signaling pathway
mnp04625  C-type lectin receptor signaling pathway
mnp04657  IL-17 signaling pathway
mnp04658  Th1 and Th2 cell differentiation
mnp04659  Th17 cell differentiation
mnp04660  T cell receptor signaling pathway
mnp04664  Fc epsilon RI signaling pathway
mnp04668  TNF signaling pathway
mnp04670  Leukocyte transendothelial migration
mnp04714  Thermogenesis
mnp04722  Neurotrophin signaling pathway
mnp04723  Retrograde endocannabinoid signaling
mnp04728  Dopaminergic synapse
mnp04750  Inflammatory mediator regulation of TRP channels
mnp04912  GnRH signaling pathway
mnp04914  Progesterone-mediated oocyte maturation
mnp04917  Prolactin signaling pathway
mnp04926  Relaxin signaling pathway
mnp04932  Non-alcoholic fatty liver disease
mnp04933  AGE-RAGE signaling pathway in diabetic complications
mnp04935  Growth hormone synthesis, secretion and action
mnp04936  Alcoholic liver disease
mnp05014  Amyotrophic lateral sclerosis
mnp05020  Prion disease
mnp05022  Pathways of neurodegeneration - multiple diseases
mnp05132  Salmonella infection
mnp05133  Pertussis
mnp05135  Yersinia infection
mnp05140  Leishmaniasis
mnp05142  Chagas disease
mnp05145  Toxoplasmosis
mnp05152  Tuberculosis
mnp05161  Hepatitis B
mnp05163  Human cytomegalovirus infection
mnp05167  Kaposi sarcoma-associated herpesvirus infection
mnp05169  Epstein-Barr virus infection
mnp05170  Human immunodeficiency virus 1 infection
mnp05171  Coronavirus disease - COVID-19
mnp05205  Proteoglycans in cancer
mnp05208  Chemical carcinogenesis - reactive oxygen species
mnp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mnp05415  Diabetic cardiomyopathy
mnp05417  Lipid and atherosclerosis
mnp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mnp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    132019083 (MAPK11)
   04015 Rap1 signaling pathway
    132019083 (MAPK11)
   04370 VEGF signaling pathway
    132019083 (MAPK11)
   04668 TNF signaling pathway
    132019083 (MAPK11)
   04068 FoxO signaling pathway
    132019083 (MAPK11)
   04071 Sphingolipid signaling pathway
    132019083 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    132019083 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    132019083 (MAPK11)
   04218 Cellular senescence
    132019083 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    132019083 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    132019083 (MAPK11)
   04613 Neutrophil extracellular trap formation
    132019083 (MAPK11)
   04620 Toll-like receptor signaling pathway
    132019083 (MAPK11)
   04621 NOD-like receptor signaling pathway
    132019083 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    132019083 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    132019083 (MAPK11)
   04660 T cell receptor signaling pathway
    132019083 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    132019083 (MAPK11)
   04659 Th17 cell differentiation
    132019083 (MAPK11)
   04657 IL-17 signaling pathway
    132019083 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    132019083 (MAPK11)
   04670 Leukocyte transendothelial migration
    132019083 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    132019083 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    132019083 (MAPK11)
   04917 Prolactin signaling pathway
    132019083 (MAPK11)
   04926 Relaxin signaling pathway
    132019083 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    132019083 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    132019083 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    132019083 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    132019083 (MAPK11)
   04722 Neurotrophin signaling pathway
    132019083 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    132019083 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    132019083 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    132019083 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    132019083 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    132019083 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    132019083 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    132019083 (MAPK11)
   05161 Hepatitis B
    132019083 (MAPK11)
   05171 Coronavirus disease - COVID-19
    132019083 (MAPK11)
   05163 Human cytomegalovirus infection
    132019083 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    132019083 (MAPK11)
   05169 Epstein-Barr virus infection
    132019083 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    132019083 (MAPK11)
   05135 Yersinia infection
    132019083 (MAPK11)
   05133 Pertussis
    132019083 (MAPK11)
   05152 Tuberculosis
    132019083 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    132019083 (MAPK11)
   05140 Leishmaniasis
    132019083 (MAPK11)
   05142 Chagas disease
    132019083 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    132019083 (MAPK11)
   05020 Prion disease
    132019083 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    132019083 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    132019083 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    132019083 (MAPK11)
   05415 Diabetic cardiomyopathy
    132019083 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    132019083 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    132019083 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    132019083 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    132019083 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mnp01001]
    132019083 (MAPK11)
Enzymes [BR:mnp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     132019083 (MAPK11)
Protein kinases [BR:mnp01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   132019083 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975 FTA2
Other DBs
NCBI-GeneID: 132019083
NCBI-ProteinID: XP_059257682
LinkDB
Position
6:444342..450951
AA seq 364 aa
MSGPRAGFYRLELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLRSIFHGANPLAVDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPDDEPEAEPYDESVEAKERTVEEWKELTYQEVLSFKPAEPPQSPGSL
EIEQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcgggcccgcgcgcaggcttctaccggctggagctgaacaagaccgtgtgggaggtg
ccgcagcggctgcaggggttgcgccccgtgggctccggcgcctacggctcggtctgctcg
gcctacgacgcgcggctgcggcagaaggtggcggtgaagaagctgtcgcgacccttccag
tcgctgatccacgcgcggagaacgtaccgcgagctgcggctgctcaagcacctgaagcac
gagaacgtcatcgggctgctggacgtgttcacgccggccacctccattgaggacttcagc
gaagtgtacctggtgaccaccctgatgggcgccgacctgaacaacatcgtcaagtgccag
gcgctgagcgacgagcacgtccagttcctggtttatcagctgctgcgcgggctgaagtac
atccactcagcggggatcatccaccgggacctgaagcccagcaacgtggcggtcaacgag
gactgtgagctgcggatcctggacttcgggctagcccgccaggctgatgaagagatgacc
ggctacgtggccactcgctggtaccgggcccccgagatcatgctgaactggatgcactac
aaccagacagtggacatctggtctgtgggctgcatcatggctgagctgctccagggaaag
gccctcttcccaggaagtgactacatcgaccagctgaagcgaatcatggaagtggtgggc
acacccagccctgaggttctagcaaagatttcctcagaacacgcccggacctacatccag
tccctgccccccatgcctcagaaggacctcaggagcatcttccatggggccaaccccctg
gctgtggacctcctgggaaggatgctggtgctggacagcgaccagagagtcagtgcggcg
gaggccctggcccatgcctacttcagccagtaccatgaccccgatgatgaacctgaggcc
gagccctacgacgagagcgttgaggccaaggagcgcaccgtggaggagtggaaggagctc
acctaccaggaagttctcagcttcaagcccgcagagccaccgcagtctcctggcagcctg
gagattgagcagtga

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