Mycolicibacterium phlei: MPHLCCUG_04493
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Entry
MPHLCCUG_04493 CDS
T04305
Symbol
nasF
Name
(GenBank) Uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mphl
Mycolicibacterium phlei
Pathway
mphl00860
Porphyrin metabolism
mphl01100
Metabolic pathways
mphl01110
Biosynthesis of secondary metabolites
mphl01120
Microbial metabolism in diverse environments
mphl01240
Biosynthesis of cofactors
Module
mphl_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mphl_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mphl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MPHLCCUG_04493 (nasF)
Enzymes [BR:
mphl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MPHLCCUG_04493 (nasF)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MPHLCCUG_04493 (nasF)
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AMO63279
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Position
complement(4579915..4581672)
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AA seq
585 aa
AA seq
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MTAQSSGRGRKPKPGRITFVGSGPGDPGLLTTRARTVLANAALVFTDPDVPEAVLALAGS
ELPPASGPEPAKPAKSEPAKSEANSDDANSDAKTDDAKTDAKSDEADKSAADETPSVPGG
PDIRSAVGDPAEVAKMLAAEARNGADVVRLVAGDPLSVDAVIAEVLAVSKSHVNFEIVPG
LPDTTAVPTYAGLPLGSTHTVADVRDPEVDWAALAAAPGPLILNATATHLPDAARTLIDH
GLIDSTPVVVTANGTTCQQRSIETTLSGLLEKGVLDLPAGLEPAGTLTGPLVVTIGKTVT
NRAKLNWWESRALYGWTVLVPRTKDQAGEMSERLISHGALPIEVPTIAVEPPRSPAQMER
AVKGLVDGRFQWVVFTSTNAVRAVWEKFNEFGLDARAFSGVKIACVGQQTADRVRAFGIN
PELVPSGEQSSLGLLDEFPPYDDVFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAY
RTVRAAPPPAHTREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAA
EFGLRVDVQPEVAAVGPLVDALAEHAARLRAEGALPPPRKKSRRR
NT seq
1758 nt
NT seq
+upstream
nt +downstream
nt
atgactgcccagagtagcgggcgaggccgtaagccgaagccgggccgcatcacgttcgtc
ggctcgggaccgggcgaccccggtctgctgacgacgcgggcgcgcaccgtgctcgccaac
gccgctttggtgttcaccgatcccgacgtgccggaagccgtgctcgccctggcgggttcc
gagctgccgccggcctcgggtcccgagcccgcgaagcccgccaagagcgagcctgccaag
agcgaagccaacagcgacgacgcgaacagcgacgccaagaccgacgacgcgaagaccgac
gccaagagcgatgaggccgacaagtccgcggccgacgagacgccgtcggtgcccggcggc
ccggacatccggtccgcggtgggcgatcccgccgaggtcgccaagatgctggccgccgag
gcgcgcaacggcgccgacgtggtccggttggtggcaggcgatccgctgtcggtcgacgcg
gtgatcgccgaggtgctggcggtgtccaagtcgcatgtgaacttcgagatcgtgcccggt
ctgccggacaccaccgcggtgccgacgtacgccgggctgccgctgggttccacgcacacc
gtcgccgatgtgcgtgaccccgaagtcgattgggccgcactggccgccgcgcccgggccg
ctgatcctcaacgccaccgcgacgcacctgccggatgccgcgcgcacgctgatcgaccac
ggtctgatcgacagcacgccggtggtggtgaccgcgaacggtacgacgtgccaacagcgt
tcgatcgagacgacgctgtccgggctgctggagaagggtgtgctggacctgcccgccggg
ctggagccggcaggcaccctgacgggcccgctggtcgtgacgatcggcaagacagtgacc
aaccgcgccaagctgaactggtgggagagccgcgccctgtacggctggaccgtgctggtg
ccgcgcaccaaggaccaggcgggcgagatgagcgagcggctgatcagccacggcgcactg
ccgatcgaggtgcccaccatcgcggtcgaaccgccgcgcagcccggcccagatggagcgc
gcggtcaagggtctggtcgacggccggttccagtgggtggtgttcacctccaccaacgcg
gtgcgtgcggtgtgggagaagttcaacgagttcggcctggacgcccgcgcgttctccggc
gtcaagatcgcctgcgtcggccagcagaccgccgaccgggtgcgcgcgttcggcatcaac
cccgaactggtgcccagcggtgagcagtcctcgctggggctgctggacgaattcccgccc
tacgacgacgttttcgatccggtgaaccgggtgctgctgccgcgcgccgacatcgccacc
gagacgctggccgaggggctgcgcgaacgcggttgggagatcgaggatgtcacggcgtac
cgcaccgtgcgcgcggccccgccgcccgcgcacacccgcgagatgatcaagaccggcggc
ttcgacgcggtgtgcttcacctcgagctcgacggtgcgcaacctggtcggcatcgcgggc
aagccgcacgcccgcacgatcgtcgcctgcatcgggccgaaaaccgctgagaccgcagcg
gagttcgggctccgggtggatgtgcagccggaggtcgcggcggtcggcccgctcgtcgac
gcgctcgccgagcacgccgcccgcttgcgtgccgagggcgcactgccgccgccgcgtaag
aagagccgccgccgctag
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