Mycobacterium tuberculosis H37Ra: MRA_3576
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Entry
MRA_3576 CDS
T00540
Name
(GenBank) 3-ketosteroid-delta-1-dehydrogenase
KO
K05898
3-oxosteroid 1-dehydrogenase [EC:
1.3.99.4
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00984
Steroid degradation
mra01100
Metabolic pathways
mra01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00984 Steroid degradation
MRA_3576
Enzymes [BR:
mra01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.99 With unknown physiological acceptors
1.3.99.4 3-oxosteroid 1-dehydrogenase
MRA_3576
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GFIT
Motif
Pfam:
FAD_binding_2
FAD_oxidored
DAO
HI0933_like
NAD_binding_8
Thi4
FAD_binding_3
Pyr_redox_2
Pyr_redox_3
GIDA
Pyr_redox
Lycopene_cycl
DUF6506
GDI
Motif
Other DBs
NCBI-ProteinID:
ABQ75361
UniProt:
A5U8L1
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Position
3984035..3985726
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AA seq
563 aa
AA seq
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MTVQEFDVVVVGSGAAGMVAALVAAHRGLSTVVVEKAPHYGGSTARSGGGVWIPNNEVLK
RRGVRDTPEAARTYLHGIVGEIVEPERIDAYLDRGPEMLSFVLKHTPLKMCWVPGYSDYY
PEAPGGRPGGRSIEPKPFNARKLGADMAGLEPAYGKVPLNVVVMQQDYVRLNQLKRHPRG
VLRSMKVGARTMWAKATGKNLVGMGRALIGPLRIGLQRAGVPVELNTAFTDLFVENGVVS
GVYVRDSHEAESAEPQLIRARRGVILACGGFEHNEQMRIKYQRAPITTEWTVGASANTGD
GILAAEKLGAALDLMDDAWWGPTVPLVGKPWFALSERNSPGSIIVNMSGKRFMNESMPYV
EACHHMYGGEHGQGPGPGENIPAWLVFDQRYRDRYIFAGLQPGQRIPSRWLDSGVIVQAD
TLAELAGKAGLPADELTATVQRFNAFARSGVDEDYHRGESAYDRYYGDPSNKPNPNLGEV
GHPPYYGAKMVPGDLGTKGGIRTDVNGRALRDDGSIIDGLYAAGNVSAPVMGHTYPGPGG
TIGPAMTFGYLAALHIADQAGKR
NT seq
1692 nt
NT seq
+upstream
nt +downstream
nt
atgactgtgcaggagttcgacgtcgtggtggtcggcagcggcgccgccggcatggttgct
gcgctggtcgccgctcaccgaggtctctcgacggtagtcgtcgagaaggccccgcactac
ggcggctccaccgcacgctcgggcggcggcgtctggatccccaacaacgaggtcctcaag
cgccgcggcgttcgagatacaccggaggcggcacgcacctatctgcacggcatcgtcggc
gaaatcgtcgagccggaacgcatcgatgcttacctcgaccgcgggcccgagatgctgtcg
ttcgtgctgaagcacacgccgctgaagatgtgctgggtacccggctactccgactactac
cccgaggctccgggcggccgcccgggcggacgttcgatcgagccgaaaccgttcaacgcg
cgcaagcttggtgccgacatggccgggctggagcccgcgtatggcaaggttccgctcaat
gtggttgtgatgcagcaggactacgttcgcctcaatcagctcaaacgtcacccccgtggc
gtgctgcgcagcatgaaggtcggcgcccgcacgatgtgggcgaaggcaacaggtaagaac
ctggtcggcatgggtcgagccctcattgggccgttgcggatcgggttgcagcgcgccgga
gtgccggtcgaactcaacaccgccttcaccgatcttttcgtcgaaaatggcgtcgtgtcc
ggggtatacgtccgcgattcccacgaggcggaatccgctgagccgcagctgatccgggct
cgccgcggcgtgatcctggcctgtggtggtttcgagcataacgagcagatgcgaatcaag
taccagcgggcacccatcaccaccgagtggaccgtgggcgccagcgccaataccggtgac
ggcattctcgccgccgaaaagctcggcgcagcactggatctgatggatgacgcttggtgg
ggcccgacggtaccgctggtcggcaaaccatggttcgcgctctcggagcgcaactctccc
ggttcgatcatcgtcaacatgtcaggcaagcgattcatgaacgaatcgatgccatacgtc
gaagcctgtcatcatatgtacggcggcgaacacggccaggggcccggaccgggcgagaac
attccggcgtggctggtgttcgaccagcgataccgggaccgctacatcttcgcgggacta
caaccagggcaacgcattccgagcaggtggctggattccggcgtcatcgtccaggccgat
acccttgcggagctggccggcaaggccggtctacccgcggacgaactcactgccaccgtc
cagcgtttcaacgcattcgcccggtccggtgtcgacgaggactaccaccgcggggaaagt
gcctacgatcgctactacggcgacccgagcaacaagcccaatccgaacctcggcgaggtc
ggccacccgccctattatggcgccaagatggttccgggcgacctggggaccaagggcggt
atccgcaccgatgtcaacggacgtgctctgcgggacgacggcagcatcatcgacggcctt
tacgctgcaggcaatgtcagtgccccagtgatgggacacacctaccccggtccgggcggc
acgataggcccggcgatgacgttcgggtacctggcggcgctgcacattgccgatcaggcg
ggaaagcgctga
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