Mycobacterium tuberculosis KZN 1435: TBMG_02849
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Entry
TBMG_02849 CDS
T00940
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase metE
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
mtb
Mycobacterium tuberculosis KZN 1435
Pathway
mtb00270
Cysteine and methionine metabolism
mtb00450
Selenocompound metabolism
mtb01100
Metabolic pathways
mtb01110
Biosynthesis of secondary metabolites
mtb01230
Biosynthesis of amino acids
Module
mtb_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
mtb00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
TBMG_02849
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
TBMG_02849
Enzymes [BR:
mtb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
TBMG_02849
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SSDB
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
VbhA
SHOCT
Motif
Other DBs
NCBI-ProteinID:
ACT25932
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Position
3150801..3153110
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AA seq
769 aa
AA seq
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MNHPSIEGQHVTQPVRRQPFTATITGSPRIGPRRELKRATEGYWAGRTSRSELEAVAATL
RRDTWSALAAAGLDSVPVNTFSYYDQMLDTAVLLGALPPRVSPVSDGLDRYFAAARGTDQ
IAPLEMTKWFDTNYHYLVPEIGPSTTFTLHPGKVLAELKEALGQGIPARPVIIGPITFLL
LSKAVDGAGAPIERLEELVPVYSELLSLLADGGAQWVQFDEPALVTDLSPDAPALAEAVY
TALCSVSNRPAIYVATYFGDPGAALPALARTPVEAIGVDLVAGADTSVAGVPELAGKTLV
AGVVDGRNVWRTDLEAALGTLATLLGSAATVAVSTSCSTLHVPYSLEPETDLDDALRSWL
AFGAEKVREVVVLARALRDGHDAVADEIASSRAAIASRKRDPRLHNGQIRARIEAIVASG
AHRGNAAQRRASQDARLHLPPLPTTTIGSYPQTSAIRVARAALRAGEIDEAEYVRRMRQE
ITEVIALQERLGLDVLVHGEPERNDMVQYFAEQLAGFFATQNGWVQSYGSRCVRPPILYG
DVSRPRAMTVEWITYAQSLTDKPVKGMLTGPVTILAWSFVRDDQPLADTANQVALAIRDE
TVDLQSAGIAVIQVDEPALRELLPLRRADQAEYLRWAVGAFRLATSGVSDATQIHTHLCY
SEFGEVIGAIADLDADVTSIEAARSHMEVLDDLNAIGFANGVGPGVYDIHSPRVPSAEEM
ADSLRAALRAVPAERLWVNPDCGLKTRNVDEVTASLHNMVAAAREVRAG
NT seq
2310 nt
NT seq
+upstream
nt +downstream
nt
gtgaaccacccgtcgatcgaaggacagcacgtgacccagcctgtacgtcgtcaacccttt
accgcaaccatcaccggctccccgcgcatcggcccgcgccgcgaactcaagcgcgccacc
gaaggctactgggccggacgtaccagccgatccgagctggaggccgtcgccgccacgtta
cgccgcgacacctggtcggccctggccgcggccggtctggactcggtgccggtgaacacc
ttctcctactacgaccaaatgctcgataccgcggtgctgctcggcgcgctgccgccccga
gtgagcccggtttccgacgggctggaccgctatttcgccgcggcgcggggcaccgaccag
atcgcgccgctggagatgacgaagtggttcgacaccaactaccactacctggtacccgag
atcgggccgtcgaccacgttcacgctgcaccccggcaaggtgctcgccgaactcaaagag
gcgttagggcaaggcattcccgcacgtccggtgatcatcgggccgatcaccttcctgctg
ctgagcaaggccgtcgacggcgcgggggcgccgatcgaacgcctcgaagagttggttccg
gtctattcggagctgctgtcgctgcttgccgacggcggcgcccagtgggtgcagttcgac
gagccggcgctggtgaccgacctctcccccgacgcgcccgccctggctgaagcggtgtac
accgcgctgtgctcggtgagcaaccggcctgcgatctatgtcgccacctacttcggggac
ccgggcgcggccctaccggcgctggctcgcaccccggtcgaagccatcggcgtcgacctg
gtggccggtgccgacacctcggtggccggggtacccgagctggccggcaagacgctggtg
gccggggtcgtcgacgggcgcaacgtctggcgcaccgacctggaggcggcgttgggcacg
ttggcgaccctgctgggttcggcggctaccgtggccgtctcgacgtcgtgctcgacactg
cacgtgccgtactcgctggaaccggaaaccgacctggatgacgcgttgcggagctggctg
gcgttcggtgccgaaaaggtgcgcgaagtcgtcgttctcgcgcgtgccctgcgcgacgga
cacgacgcggtcgccgacgagatcgcgtcgtcccgcgccgccatcgcgtcccgcaagcgc
gacccgcggttacacaatgggcaaatccgggcgcgcatcgaggcgatcgtcgcgtccgga
gcccaccgcggcaatgccgcccagcgccgcgccagccaagacgcgcgactgcacctgccg
ccgctgccgaccacgacgatcggctcctacccgcagacctcggcgatccgcgttgcgcgt
gcggcgctgcgggccggtgagatcgacgaggccgagtacgtgcgccggatgcggcaagag
atcaccgaggtgatcgcgctacaggagcggctcgggctcgacgtgctggtgcacggcgaa
ccggagcgcaacgacatggtgcagtacttcgccgagcaattggcgggtttcttcgctacc
cagaacggctgggtgcagtcctacggcagccgctgtgtgcgtccgccgatcctgtacggc
gacgtgtcccggccgcgggcgatgacggtcgagtggatcacctacgcgcagtcgctgacc
gacaaaccggtgaagggcatgttgaccgggccggtgacgattctggcgtggtcgttcgtg
cgtgacgaccagccgttggccgataccgccaaccaggtggcgctggcgattcgcgacgag
accgtggatttgcagtccgccggcatcgcggtcatccaggtcgacgagcctgcgctgcgt
gaactgctgccgctgcgtcgcgccgaccaggccgagtacttgcgttgggcggtaggggct
ttccggttggccacctccggcgtctcggacgccacccagatccacacgcatctgtgctac
tcggagttcggcgaggtgatcggcgcgatcgccgatctggacgcggacgtcacgtccatc
gaggcggcccggtcacacatggaggtgctcgacgacctgaacgcgatcggcttcgccaac
ggtgtgggcccgggcgtctatgacattcactcgccacgggtgccctccgctgaggagatg
gccgactcgttgcgggccgcgttgcgcgcggtgccggccgagcggctgtgggtcaacccc
gactgcggactgaagacccgcaatgtcgacgaggtgaccgcgtcgctgcacaacatggtc
gccgccgcccgggaggtgcgcgcgggctag
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