Macaca thibetana thibetana (Pere David's macaque): 126929447
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Entry
126929447 CDS
T08579
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb01522
Endocrine resistance
mthb04010
MAPK signaling pathway
mthb04015
Rap1 signaling pathway
mthb04068
FoxO signaling pathway
mthb04071
Sphingolipid signaling pathway
mthb04114
Oocyte meiosis
mthb04148
Efferocytosis
mthb04218
Cellular senescence
mthb04261
Adrenergic signaling in cardiomyocytes
mthb04370
VEGF signaling pathway
mthb04380
Osteoclast differentiation
mthb04550
Signaling pathways regulating pluripotency of stem cells
mthb04611
Platelet activation
mthb04613
Neutrophil extracellular trap formation
mthb04620
Toll-like receptor signaling pathway
mthb04621
NOD-like receptor signaling pathway
mthb04622
RIG-I-like receptor signaling pathway
mthb04625
C-type lectin receptor signaling pathway
mthb04657
IL-17 signaling pathway
mthb04658
Th1 and Th2 cell differentiation
mthb04659
Th17 cell differentiation
mthb04660
T cell receptor signaling pathway
mthb04664
Fc epsilon RI signaling pathway
mthb04668
TNF signaling pathway
mthb04670
Leukocyte transendothelial migration
mthb04714
Thermogenesis
mthb04722
Neurotrophin signaling pathway
mthb04723
Retrograde endocannabinoid signaling
mthb04728
Dopaminergic synapse
mthb04750
Inflammatory mediator regulation of TRP channels
mthb04912
GnRH signaling pathway
mthb04914
Progesterone-mediated oocyte maturation
mthb04917
Prolactin signaling pathway
mthb04926
Relaxin signaling pathway
mthb04932
Non-alcoholic fatty liver disease
mthb04933
AGE-RAGE signaling pathway in diabetic complications
mthb04935
Growth hormone synthesis, secretion and action
mthb04936
Alcoholic liver disease
mthb05014
Amyotrophic lateral sclerosis
mthb05020
Prion disease
mthb05022
Pathways of neurodegeneration - multiple diseases
mthb05132
Salmonella infection
mthb05133
Pertussis
mthb05135
Yersinia infection
mthb05140
Leishmaniasis
mthb05142
Chagas disease
mthb05145
Toxoplasmosis
mthb05152
Tuberculosis
mthb05161
Hepatitis B
mthb05163
Human cytomegalovirus infection
mthb05167
Kaposi sarcoma-associated herpesvirus infection
mthb05169
Epstein-Barr virus infection
mthb05170
Human immunodeficiency virus 1 infection
mthb05171
Coronavirus disease - COVID-19
mthb05205
Proteoglycans in cancer
mthb05208
Chemical carcinogenesis - reactive oxygen species
mthb05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mthb05415
Diabetic cardiomyopathy
mthb05417
Lipid and atherosclerosis
mthb05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
126929447
04015 Rap1 signaling pathway
126929447
04370 VEGF signaling pathway
126929447
04668 TNF signaling pathway
126929447
04068 FoxO signaling pathway
126929447
04071 Sphingolipid signaling pathway
126929447
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
126929447
09143 Cell growth and death
04114 Oocyte meiosis
126929447
04218 Cellular senescence
126929447
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
126929447
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
126929447
04613 Neutrophil extracellular trap formation
126929447
04620 Toll-like receptor signaling pathway
126929447
04621 NOD-like receptor signaling pathway
126929447
04622 RIG-I-like receptor signaling pathway
126929447
04625 C-type lectin receptor signaling pathway
126929447
04660 T cell receptor signaling pathway
126929447
04658 Th1 and Th2 cell differentiation
126929447
04659 Th17 cell differentiation
126929447
04657 IL-17 signaling pathway
126929447
04664 Fc epsilon RI signaling pathway
126929447
04670 Leukocyte transendothelial migration
126929447
09152 Endocrine system
04912 GnRH signaling pathway
126929447
04914 Progesterone-mediated oocyte maturation
126929447
04917 Prolactin signaling pathway
126929447
04926 Relaxin signaling pathway
126929447
04935 Growth hormone synthesis, secretion and action
126929447
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
126929447
09156 Nervous system
04728 Dopaminergic synapse
126929447
04723 Retrograde endocannabinoid signaling
126929447
04722 Neurotrophin signaling pathway
126929447
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
126929447
09158 Development and regeneration
04380 Osteoclast differentiation
126929447
09159 Environmental adaptation
04714 Thermogenesis
126929447
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
126929447
05208 Chemical carcinogenesis - reactive oxygen species
126929447
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
126929447
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
126929447
05161 Hepatitis B
126929447
05171 Coronavirus disease - COVID-19
126929447
05163 Human cytomegalovirus infection
126929447
05167 Kaposi sarcoma-associated herpesvirus infection
126929447
05169 Epstein-Barr virus infection
126929447
09171 Infectious disease: bacterial
05132 Salmonella infection
126929447
05135 Yersinia infection
126929447
05133 Pertussis
126929447
05152 Tuberculosis
126929447
09174 Infectious disease: parasitic
05145 Toxoplasmosis
126929447
05140 Leishmaniasis
126929447
05142 Chagas disease
126929447
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
126929447
05020 Prion disease
126929447
05022 Pathways of neurodegeneration - multiple diseases
126929447
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
126929447
05418 Fluid shear stress and atherosclerosis
126929447
05415 Diabetic cardiomyopathy
126929447
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
126929447
04932 Non-alcoholic fatty liver disease
126929447
04933 AGE-RAGE signaling pathway in diabetic complications
126929447
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
126929447
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mthb01001
]
126929447
Enzymes [BR:
mthb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
126929447
Protein kinases [BR:
mthb01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
126929447
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Motif
Other DBs
NCBI-GeneID:
126929447
NCBI-ProteinID:
XP_050601745
LinkDB
All DBs
Position
10:536085..546019
Genome browser
AA seq
390 aa
AA seq
DB search
MSSPPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRVSPGGGATHQPSPSAIPRLHVLPDLKPG
NLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMA
EMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASIL
TNASPLAVNLLEKMLVLDAEQRVTAAEALAHPYFESLHDTEDEPQVQKYDDSFDDVDRTL
DEWKRVTYKEVLSFKPPRQLGARVSKETAL
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgagctctccgccgcctgcccgcagtggcttttaccgccaggaggtgaccaagacggcc
tgggaggtgcgcgccgtgtaccgggacctgcagcccgtgggctcgggcgcctatggcgcg
gtgtgctcggccgtggacagccgcaccggcgctaaggtggccatcaagaagctgtaccgg
cccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagcac
atgcgccacgagaacgtgattgggctgctggatgtgttcactcctgatgagaccctggat
gacttcacagacttttacctggtgatgccattcatgggcaccgacctgggcaagcttatg
aaacatgagaagctgggcgaggaccggatccagttcctcgtgtaccagatgctgaagggg
ctgaggtatatccatgctgccggcatcatccacagagtgagtcctggtggaggagccacc
catcagccctcccccagcgcaatcccccgcctccacgtcctacctgacctgaagcctggc
aacctggctgtgaacgaagactgtgagctgaagatcctggactttggcctggccaggcag
gcagacagcgagatgactggctatgtggtgacccggtggtaccgggcacccgaggtcatc
ttgaattggatgcgctacacgcagacggtggacatctggtctgtggggtgcatcatggcg
gagatgatcacaggcaagacgctgttcaaaggcagcgaccacctggaccagctgaaggag
atcatgaaagtgacagggacgcctccagctgagtttgtgcagcggctgcagagtgatgag
gccaagaactacatgaagggcctccctgagttggagaagaaggattttgcctccatcctg
accaatgcaagccctctggctgtgaacctcctggagaagatgctggtgctggatgcggag
cagcgggtgacggcagccgaggcactggcccatccctacttcgagtccctgcacgacacg
gaagatgagccccaggtccagaagtatgacgactcctttgatgacgtggaccgcacgctg
gatgaatggaagcgtgttacttacaaagaggtgctcagcttcaagcctccccggcagctg
ggagccagggtctccaaggagacggctctgtga
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