Nocardiopsis exhalans: NE857_17230
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Entry
NE857_17230 CDS
T08285
Name
(GenBank) uroporphyrinogen-III synthase
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
nex
Nocardiopsis exhalans
Pathway
nex00860
Porphyrin metabolism
nex01100
Metabolic pathways
nex01110
Biosynthesis of secondary metabolites
nex01120
Microbial metabolism in diverse environments
nex01240
Biosynthesis of cofactors
Module
nex_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
nex_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
nex_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
nex00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NE857_17230
Enzymes [BR:
nex01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
NE857_17230
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Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
USY17106
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Position
3887088..3888236
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AA seq
382 aa
AA seq
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MTTAVPASPTTSEATTAPLAGFTVAVTAARRAEELTALLHRKGAQVIAAPALRIVPLSDD
QRLASVSEQLTRTPADVVIATTGIGFRGWVEACETWGMAEPLLTSMKSSRLLARGPKAKG
AIRAAGLNEEWSPPSESSAEVLDYLLEHGVQGLRVAIQLHGEPLPDFTAALRLAGAEVIE
VPVYRWTQPEQTEPLDRLIEAVTTGGVDAVTFTSAPAAAGLLARAHTTGQQHALIGALRG
HVLCLCVGPVTARPLMAHDIPTVWPDRARIGAQVRKLTEELPARFPTLNVAGHRLRLRGH
AVLVDGTVHTLSPTLMRLMRALAHRPGQVRDRAHLLTCLGEDADAHAVETAVARLRTALG
DPKIIQTVVKRGYRLALDSHPC
NT seq
1149 nt
NT seq
+upstream
nt +downstream
nt
atgaccactgccgtgcccgcctcaccgaccaccagcgaggccaccaccgcacccctggcc
gggttcaccgtcgccgtcaccgccgcccgccgcgccgaggaactcaccgccctgctccac
cgcaagggcgcccaggtcatcgccgcacccgccctgcgcatcgtccccttgagcgacgac
caacgcctggcctcggtctccgaacaactcacccgcacccccgccgacgtcgtcatcgcc
accaccggcatcggcttccgcggctgggtcgaggcctgcgaaacctggggcatggccgaa
cccctcctgaccagcatgaaatcctcacgcctgctcgcccgcggccccaaagccaaaggc
gccatccgcgccgccggactcaacgaggaatggtccccaccctcagaatcctccgccgaa
gtcctggactacctcctcgaacacggcgtccaaggcctacgcgtggccatccaactccac
ggcgaacccctacccgacttcaccgccgccctacgcctggccggagccgaagtcatcgag
gtccctgtctaccgctggacccaacccgaacagaccgaacccctggaccgcctcatcgag
gccgtcaccaccgggggagtggacgccgtcaccttcaccagcgccccggccgccgccgga
ctcctcgcccgcgcccacaccaccggccaacaacacgccctcatcggcgccctgcgcggc
cacgtgctctgcctgtgcgtgggaccggtcaccgcacgccccctgatggcccacgacatc
cccaccgtgtggcccgaccgcgcacgcatcggcgcccaggtccgcaaactcaccgaagaa
ctccccgcccgcttccccaccctcaacgtggccggacaccgcctacggctgcgcggccac
gccgtcctggtcgacggcaccgtccacaccctctcgcccaccctgatgcgcctgatgcgc
gccctggcccaccgccccggccaggtccgcgaccgcgcccacctgctcacctgcctgggc
gaggacgccgacgcccacgccgtcgaaacggccgtggcccgtctgcgcaccgccctgggc
gaccccaagatcatccaaacggtcgtcaaacgcggctaccgcctggccctggactcccac
ccatgctga
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