Nomascus leucogenys (northern white-cheeked gibbon): 100601700
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Entry
100601700 CDS
T03265
Gene name
ERBB2
Definition
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01521
EGFR tyrosine kinase inhibitor resistance
nle01522
Endocrine resistance
nle01524
Platinum drug resistance
nle04010
MAPK signaling pathway
nle04012
ErbB signaling pathway
nle04020
Calcium signaling pathway
nle04066
HIF-1 signaling pathway
nle04151
PI3K-Akt signaling pathway
nle04510
Focal adhesion
nle04520
Adherens junction
nle04530
Tight junction
nle05200
Pathways in cancer
nle05205
Proteoglycans in cancer
nle05206
MicroRNAs in cancer
nle05212
Pancreatic cancer
nle05213
Endometrial cancer
nle05215
Prostate cancer
nle05219
Bladder cancer
nle05223
Non-small cell lung cancer
nle05224
Breast cancer
nle05226
Gastric cancer
nle05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100601700 (ERBB2)
04012 ErbB signaling pathway
100601700 (ERBB2)
04066 HIF-1 signaling pathway
100601700 (ERBB2)
04020 Calcium signaling pathway
100601700 (ERBB2)
04151 PI3K-Akt signaling pathway
100601700 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100601700 (ERBB2)
04520 Adherens junction
100601700 (ERBB2)
04530 Tight junction
100601700 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100601700 (ERBB2)
05206 MicroRNAs in cancer
100601700 (ERBB2)
05205 Proteoglycans in cancer
100601700 (ERBB2)
05230 Central carbon metabolism in cancer
100601700 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
100601700 (ERBB2)
05226 Gastric cancer
100601700 (ERBB2)
05219 Bladder cancer
100601700 (ERBB2)
05215 Prostate cancer
100601700 (ERBB2)
05213 Endometrial cancer
100601700 (ERBB2)
05224 Breast cancer
100601700 (ERBB2)
05223 Non-small cell lung cancer
100601700 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100601700 (ERBB2)
01524 Platinum drug resistance
100601700 (ERBB2)
01522 Endocrine resistance
100601700 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nle01001
]
100601700 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
nle04147
]
100601700 (ERBB2)
04090 CD molecules [BR:
nle04090
]
100601700 (ERBB2)
Enzymes [BR:
nle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100601700 (ERBB2)
Protein kinases [BR:
nle01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100601700 (ERBB2)
Exosome [BR:
nle04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
100601700 (ERBB2)
CD molecules [BR:
nle04090
]
Proteins
100601700 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100601700
NCBI-ProteinID:
XP_030664092
Ensembl:
ENSNLEG00000000989
LinkDB
All DBs
Position
Unknown
AA seq
1255 aa
AA seq
DB search
MELAALCGWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLNNTTLVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLA
LTLIDTNRSRACQPCSPVCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLS
DLSVFQNLQVIRGRILHNGAYSLTLQGVGISWLGLRSLRELGSGLALIHHNNRLCFVHTV
PWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVSCAHYKDPPFCVARC
PSGVKPDLSYMPIWKFPDEEGTCQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVG
ILLVVVLGAVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLPAHDPSPLQRYSEDPTVPLPSETDGYVTPLTCSLQPEYV
NQPDVRPQPPSPREGPLPPARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLAPR
GGAAPQPHPPPAFSPAFDNLYYWDQDPSERGAPPSTFKGTPTAENPEYLGLDVPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggccttgtgcggctgggggctcctcctcgccctcttgccccccggagcc
gcgagcacccaagtgtgcaccggcacagacatgaagctgcggctccctgccagtcccgag
acccacctggacatgctccgccacctctaccagggctgccaggtggtgcagggaaacctg
gaactcacctacctgcccaccaatgccagcctctccttcctgcaggatatccaggaggta
cagggctacgtgctcatcgctcacaaccaagtgaggcaggtcccactgcagaggctgcgg
attgtgcgaggcacccagctctttgaggacaactatgccctggctgtgctagacaatgga
gacccgctgaacaataccacccttgtcacaggggcctccccaggaggcctgcgggagctg
cagcttcgaagcctcacagagatcttgaaaggaggggtcttgatccagcggaacccccag
ctctgctaccaggacacgattttgtggaaggatatcttccacaagaacaaccagctggct
ctcacactgatagacaccaaccgctctcgggcctgtcagccctgttctccggtgtgtaag
ggctcccgctgctggggagagagttctgaggattgtcagagcctgacgcgcactgtctgt
gctggtggctgtgcccgctgcaaggggccactgcccactgactgctgccatgagcagtgt
gctgccggctgcacgggccccaagcactctgattgcctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacagacacctttgag
tccatgcccaatcccgagggccggtatacattcggcgccagctgtgtgactgcctgtccc
tacaactacctttctacggacgtgggatcctgcaccctcgtttgccccctgcacaaccaa
gaggtgacagcagaggacggaacacagcggtgtgagaagtgcagcaagccctgtgcccga
gtgtgctatggtctgggcatggagcacttgcgagaggtgagggcagtcaccagtgccaat
atccaggagtttgctggctgcaagaagatctttgggagcctggcatttctgccggagagc
tttgatggggacccagcctccaacaccgccccgctccagccagagcagctccaagtgttt
gagactctggaagagatcacaggttacttatacatctcagcatggccagacagcctgtct
gacctcagcgtcttccagaacctgcaagtaatccggggacgaattctgcacaatggcgcc
tactcgctgaccctgcaaggggtgggcatcagctggctggggctgcgctcgctgcgggaa
ctgggcagtggactggccctcatccaccataacaaccgcctctgcttcgtgcacacggtg
ccctgggaccagctcttccggaacccgcaccaagccctgctccacactgccaaccggcca
gaggacgagtgtgtgggcgagggcctggcctgccaccagctgtgcgcccgagggcactgc
tggggtccagggcccacccagtgtgtcaactgcagccagttccttcggggccaggagtgc
gtggaggaatgccgagtactgcaggggcttcccagggagtatgtgaatgccaggcactgt
ttgccatgccaccccgagtgtcagccccagaatggctcagtgacctgttttggaccggag
gctgaccagtgtgtgtcctgtgcccactataaagaccctcccttctgcgtggcccgctgc
cccagcggtgtgaaacctgacctctcctacatgcccatctggaagtttccagatgaggag
ggcacgtgccagccttgccccatcaactgcacccactcctgtgtggacctggatgacaag
ggctgccccgctgagcagagagccagccctctgacgtccatcatctctgcggtggtgggc
atcctgctggtcgtggtcttgggggcggtctttgggatcctcatcaagcgacgacagcag
aagatccggaagtacacgatgcggaggctgctgcaggaaacggagctggtggagccgctg
acacctagcggagcgatgcccaaccaggcgcagatgcggatcctgaaagagacggagctg
aggaaggtgaaggtgcttggatctggcgcttttggcacagtctacaagggcatctggatc
cctgatggggagaatgtgaaaattccagtggccatcaaagtgttgagggaaaacacatcc
cccaaagccaacaaagaaatcttagacgaagcatacgtgatggctggtgtgggctcccca
tatgtttcccgcctcctgggcatctgcctgacatccacggtgcagctggtgacacagctt
atgccctatggctgcctcttagaccatgtccgggaaaaccgcggacgcctgggctcccag
gacctgctgaactggtgtatgcagattgccaaggggatgagctacctggaggatgtgcgg
ctcgtacacagggacttggctgctcggaacgtgctggtcaagagtcccaaccatgtcaaa
attacagacttcgggctggctcggctgctggacattgacgagacagagtaccatgcagat
gggggcaaggtgcccatcaagtggatggcactggagtccattctccgccggcggttcacc
caccagagtgatgtgtggagttatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggaaaagggggagcgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgtcggccgagattccgggagttggtgtctgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaggacttgggccctgccagtcccttg
gacagcaccttctaccgctcactgctggaggatgatgacatgggggacctggtggatgct
gaggagtatctggtaccccagcagggcttcttctgtccagaccctgccccgggtgctggg
ggcatggtccaccacaggcaccgcagctcatctaccaggagtggcggtggggacctgacg
ctagggctggagccctcagaagaggaggcccccaggtctccactggcaccctccgaaggg
gctggctccgatgtatttgatggtgacctgggaatgggggcagccaaggggctgcaaagc
ctccccgcacatgaccccagccctctacagcggtacagtgaggaccccacagtacccctg
ccctctgagactgacggctacgttacccccctgacctgcagcctccagcccgaatatgtg
aaccagccagatgttcggccacaacccccttcgccccgagagggccctctgcctcctgcc
cgacctgctggtgccactctggaaaggcccaagactctctccccagggaagaatggggtc
gtcaaagacgtttttgcctttgggggtgctgtggagaaccccgagtacttggcaccccgg
ggaggagctgcccctcagccccaccctcctccggccttcagcccagccttcgacaacctc
tattactgggaccaggacccatcagagcggggggctccacccagcaccttcaaagggaca
cctacggcagagaacccagagtacctgggtctggacgtgccagtgtga
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integrated database retrieval system
