Nomascus leucogenys (northern white-cheeked gibbon): 100603207
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Entry
100603207 CDS
T03265
Gene name
PDGFRA
Definition
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01521
EGFR tyrosine kinase inhibitor resistance
nle04010
MAPK signaling pathway
nle04014
Ras signaling pathway
nle04015
Rap1 signaling pathway
nle04020
Calcium signaling pathway
nle04072
Phospholipase D signaling pathway
nle04144
Endocytosis
nle04151
PI3K-Akt signaling pathway
nle04510
Focal adhesion
nle04540
Gap junction
nle04630
JAK-STAT signaling pathway
nle04810
Regulation of actin cytoskeleton
nle05163
Human cytomegalovirus infection
nle05200
Pathways in cancer
nle05206
MicroRNAs in cancer
nle05214
Glioma
nle05215
Prostate cancer
nle05218
Melanoma
nle05230
Central carbon metabolism in cancer
nle05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100603207 (PDGFRA)
04014 Ras signaling pathway
100603207 (PDGFRA)
04015 Rap1 signaling pathway
100603207 (PDGFRA)
04630 JAK-STAT signaling pathway
100603207 (PDGFRA)
04020 Calcium signaling pathway
100603207 (PDGFRA)
04072 Phospholipase D signaling pathway
100603207 (PDGFRA)
04151 PI3K-Akt signaling pathway
100603207 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100603207 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100603207 (PDGFRA)
04540 Gap junction
100603207 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100603207 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100603207 (PDGFRA)
05206 MicroRNAs in cancer
100603207 (PDGFRA)
05230 Central carbon metabolism in cancer
100603207 (PDGFRA)
05231 Choline metabolism in cancer
100603207 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
100603207 (PDGFRA)
05218 Melanoma
100603207 (PDGFRA)
05215 Prostate cancer
100603207 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
100603207 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100603207 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nle01001
]
100603207 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
nle04090
]
100603207 (PDGFRA)
Enzymes [BR:
nle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100603207 (PDGFRA)
Protein kinases [BR:
nle01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
100603207 (PDGFRA)
CD molecules [BR:
nle04090
]
Proteins
100603207 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
V-set
Herpes_gE
C2-set_2
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100603207
NCBI-ProteinID:
XP_030674789
Ensembl:
ENSNLEG00000008285
LinkDB
All DBs
Position
9
AA seq
1089 aa
AA seq
DB search
MGTSHPAFLVLGCLLTGLSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLRNSEGVVPASYNSRQGFNG
TFTVGPYTCEAIVKGKKFQTIAFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVK
EMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVQAYPPPRISWLKNNLTLIENL
TEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNEDAVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNVSNIITEIHPRD
RSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMT
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTCKNEEDKLKDWEGGLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccatccggcgttcctggtcttaggctgtcttctcacagggctgagccta
atcctctgccagctttcattaccctctatccttccaaatgaaaatgaaaaggtcgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaactccgatgtggaaatcagaaatgaagaaaacaacagtggcctt
tttgtgacggtcttggaagtgagcagtgcctcggcggcccacacagggttgtacacttgt
tattacaaccacactcagacagaagagaatgagcttgaaggcaggcacatttacatctat
gtgccagacccagatgtagccttcgtacctctaggaatgacggattatttagtcatcgtg
gaggacgatgattctgccatcataccttgtcgcacaactgatcccgagacccctgtaacc
ttacgcaacagtgagggggtggtacctgcctcctacaacagcagacagggctttaatggg
acattcactgtagggccctatacctgtgaggccatcgtcaaaggaaagaagttccagacc
atcgcatttaacgtttatgctttaaaagcaacatcagagctggatctagaaatggaagct
cttaaaaccgtgtataagtcaggggaaacgattgtggtcacctgtgctgttttcaacaat
gaggtggttgaccttcaatggacgtaccctggagaagtgaaaggcaaaggcatcacaatg
ctggaagaaatcaaagtcccatccatcaaattggtgtacactttgacggtccccgaggcc
acggtgaaagacagtggagattacgaatgtgctgcccgccaggctaccagggaggtcaaa
gaaatgaagaaagtcactatttctgtccatgagaaagggttcattgaaatcaaacctacc
ttcagccagttggaagctgtcaacctgcatgaagtcaaacattttgttgtagaggtgcag
gcctacccacctcccaggatatcctggctgaaaaacaatctgactctgattgaaaatctc
actgagatcaccactgacgtggaaaagattcaggaaataaggtatcgaagcaaattaaag
ctgatccgtgctaaggaagaagacagtggccattatactattgtagctcaaaatgaagat
gctgtgaagagctatacttttgaactgttaactcaagttccttcatccattctggactta
gtcgatgatcaccatggctcaactgggggacagacagtgaggtgcacagctgaaggcacg
ccgcttcctgatattgagtggatgatatgcaaggatattaagaaatgtaataatgaaact
tcctggacgattttggccaacaatgtctcaaatatcatcacggagatccacccccgagac
aggagtaccgtggagggccgtgtgactttcgccaaagtggaggagaccattgcggtgcga
tgcctggctaagaatctccttggagctgagaaccgagagctgaagctggtggctcccacc
ctgcgttctgaactcacggtggctgctgcagtcctggtgctgctggtgattgtgatcatc
tcactcattgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgctggagg
gtcattgaatcaatcagcccggatggacatgaatatatttatgtggacccgatgcagctg
ccttatgactcaagatgggagtttccaagggatggactagtgcttggtcgggtcttgggg
tctggagcgtttgggaaggtggttgaaggaacagcctatggattaagccggtcccaacct
gtcatgaaagttgcagtgaagatgctaaaacccacggccagatccagtgaaaaacaagct
ctcatgtctgaactgaagataatgactcacctggggccacatttgaacattgtaaacttg
ctgggagcctgcaccaagtcaggccccatttacatcatcacggagtactgcttctacgga
gatttggtcaactatttgcataagaatagggatagcttcctgagccaccacccagagaag
ccaaagaaagagctggatatctttggattgaaccctgctgatgaaagcacacggagctat
gttattttatcttttgaaaacaatggtgactacatggacatgaagcaggctgatactaca
cagtatgtccccatgctagaaaggaaagaggtttctaaatattccgacatccagagatca
ctctatgatcgtccagcctcatataagaagaaatctatgttagactcagaagtcaaaaac
ctcctttcagatgataactcagaaggccttactttattggatttgttgagcttcacctat
caagttgcccgaggaatggagtttttggcttcaaaaaattgtgtccaccgtgatctggct
gctcgcaacgtcctcctggcacaaggaaaaatcgtgaagatctgtgactttggcctagct
agagacatcatgcatgattcgaactacgtgtcgaaaggcagtacctttctgcccgtgaag
tggatggctcctgagagcatctttgacaacctctacaccacactgagtgatgtctggtct
tacggcattctgctctgggagatcttttcccttggtggcaccccttaccccggcatgacg
gtggattctactttctacaataagatcaagagtgggtaccggatggccaagcctgaccac
gctaccagtgaagtctacgagatcatggtgaaatgctggaacagtgagccggagaagaga
ccctccttttaccacctgagtgagattgtggagaatctgctgcctggacaatataaaaag
agttatgaaaaaattcacctggacttcctgaagagtgaccatcctgctgtggcacgcatg
cgtgtggactcagacaatgcgtacattggtgtcacctgcaaaaacgaggaagacaagctg
aaggactgggagggtggtctggatgagcagagactgagcgctgacagtggctacatcatt
cctctgcctgacattgaccctgtccctgaggaggaggacctgggcaagaggaacagacac
agttcgcagacctctgaagagagcgccattgagacgggttccagcagttccaccttcatc
aagagagaggacgagaccattgaagacatcgacatgatggatgacatcgggatagactct
tcagacctggtggaagacagcttcctgtaa
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integrated database retrieval system
