Orcinus orca (killer whale): 101269820
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Entry
101269820 CDS
T05247
Symbol
CHKA
Name
(RefSeq) choline kinase alpha isoform X1
KO
K14156
choline/ethanolamine kinase [EC:
2.7.1.32
2.7.1.82
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00564
Glycerophospholipid metabolism
oor01100
Metabolic pathways
oor05231
Choline metabolism in cancer
Module
oor_M00090
Phosphatidylcholine (PC) biosynthesis, choline => PC
oor_M00092
Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
101269820 (CHKA)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
101269820 (CHKA)
Enzymes [BR:
oor01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.32 choline kinase
101269820 (CHKA)
2.7.1.82 ethanolamine kinase
101269820 (CHKA)
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Gene cluster
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Motif
Pfam:
Choline_kinase
APH
EcKL
Kdo
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
101269820
NCBI-ProteinID:
XP_004278080
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Position
8:5093795..5156457
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AA seq
448 aa
AA seq
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MKTKFCNGSEAEPSPLGLLLSCGSGSATPAPGVGQQRDAASDLEPKQLGGRQPQLALPPP
PLPLPPPPPADDQPEPRTRRRAYLWCKEFLSGAWRGLREDQFHISVIRGGLSNMLFQCSL
PDTLATVGDEPRKVLLRLYGAILKMRSCNKEGSEQAQKDNEFQGAEAMVLESVMFAILAE
RSLGPKLFGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMARFHGMKMPFNKEPKWL
FGTMEKYLNQVLRIKFTGESKVKQLHKFLSYNLPLELENLRSLLESTPSPVVFCHNDCQE
GNILLLEGRENSENQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYNYEKYPLFRANILKY
PTRKQQLHFISNYLAAFQNEFENLSTEEKSVIEEEMLLEVNRFALASHFFWGLWSIVQAK
ISSIEFGYMEYAQARFDAYFDQKRKLGV
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgaagaccaagttctgcaacgggagcgaggcggagccctcgccgctcgggctgctgctg
agctgcggcagcggcagcgcgaccccggcgcccggcgtggggcagcagcgcgacgccgcc
agtgacctcgagcccaagcagctgggcgggcggcagccgcagctcgcgctgccgccgccg
ccgctgccgctgcccccgccgccgccggccgacgatcagcccgagcccaggacgcggcgc
agggcctatctgtggtgcaaggagttcctgtccggcgcctggcggggccttcgcgaggac
cagttccacatcagtgtcatcagaggtggcctcagtaacatgctgttccagtgctcctta
cccgacactctggccaccgttggtgacgagcctcggaaggtgctcctgcggctgtacggt
gcaattctaaagatgcggtcctgtaataaggagggatccgaacaagctcagaaagacaat
gaatttcaaggcgccgaggccatggttctggagagcgttatgtttgccatccttgcagag
aggtcgctggggccaaagctctttggcatcttcccccaaggccgcctggagcagtttatc
ccgagccggcgattagacactgaagaattaagtttgccagatatttctgcagaaatagct
gagaaaatggccagatttcatggtatgaaaatgccattcaataaggaaccaaaatggctt
tttggaacaatggaaaaatacctgaatcaagtgctgagaattaaatttactggggaatcc
aaagttaagcagctccacaaattcctcagttacaacctgcctttggaactagaaaacctg
agatcattacttgaatccactccatctcccgtcgtgttttgtcacaatgactgtcaggaa
ggtaatatcttattgctggaaggcagggagaattctgaaaaccagaaactgatgctcatc
gactttgaatacagcagttacaactacaggggattcgacattgggaatcatttctgtgaa
tggatgtacgattataattacgaaaagtaccctcttttcagagcaaacatcctgaagtat
cccaccaggaagcaacagctccatttcatttccaattacttggctgcattccaaaatgaa
tttgaaaacctcagtactgaagaaaagtccgttatagaagaagaaatgttgcttgaagtc
aataggtttgcccttgcgtcccatttcttctggggactttggtccatcgtacaggccaag
atttcatccattgaatttgggtacatggagtatgcccaggccaggttcgatgcctatttc
gaccagaagaggaagcttggggtgtga
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