KEGG   Orcinus orca (killer whale): 101276819
Entry
101276819         CDS       T05247                                 
Symbol
GSTO1
Name
(RefSeq) glutathione S-transferase omega-1 isoform X3
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor00480  Glutathione metabolism
oor00980  Metabolism of xenobiotics by cytochrome P450
oor00982  Drug metabolism - cytochrome P450
oor00983  Drug metabolism - other enzymes
oor01100  Metabolic pathways
oor01524  Platinum drug resistance
oor05200  Pathways in cancer
oor05204  Chemical carcinogenesis - DNA adducts
oor05207  Chemical carcinogenesis - receptor activation
oor05208  Chemical carcinogenesis - reactive oxygen species
oor05225  Hepatocellular carcinoma
oor05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oor00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101276819 (GSTO1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101276819 (GSTO1)
   00982 Drug metabolism - cytochrome P450
    101276819 (GSTO1)
   00983 Drug metabolism - other enzymes
    101276819 (GSTO1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101276819 (GSTO1)
   05204 Chemical carcinogenesis - DNA adducts
    101276819 (GSTO1)
   05207 Chemical carcinogenesis - receptor activation
    101276819 (GSTO1)
   05208 Chemical carcinogenesis - reactive oxygen species
    101276819 (GSTO1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101276819 (GSTO1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101276819 (GSTO1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101276819 (GSTO1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:oor02000]
    101276819 (GSTO1)
Enzymes [BR:oor01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101276819 (GSTO1)
Transporters [BR:oor02000]
 Other transporters
  Pores ion channels [TC:1]
   101276819 (GSTO1)
SSDB
Motif
Pfam: GST_N_2 GST_N_3 GST_N GST_C GST_C_3 GST_C_2 CLIC-like_N Glutaredoxin Zona_CL2
Other DBs
NCBI-GeneID: 101276819
NCBI-ProteinID: XP_004265924
LinkDB
Position
14:66152140..66161324
AA seq 241 aa
MSGGSARSLGKGSAPPGQVPEGLIRVYSMRFCPFAKRTLLVLKAKGIGHEVININLKNKP
EWFFKKNPFGLVPVLENSQGQVIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMVFELF
SKVPPLLLSFLRRQNKEDCSGLKEELHKEFSKLEEVLTNKKTTFFGGSSLSMIDYLIWPW
FEWLVALELNEYVNHTPNLKLWMEAMMKDPAVSSLFIDPKAFRGFLDLYLQNNLEACDYG
L
NT seq 726 nt   +upstreamnt  +downstreamnt
atgtccggagggtcagccaggagcctggggaagggaagcgcgcccccggggcaggtcccc
gagggcctgattcgcgtctacagcatgaggttctgcccgttcgccaagaggacgctcctg
gtcctgaaggccaagggaattgggcatgaagtcattaacatcaacctaaaaaataagcct
gagtggttcttcaagaagaatcccttcggcctggtgccagttctggaaaacagtcagggt
caagtgatctacgaatctgccatcacttgtgagtacctggatgaagcatatccaggaaag
aagctgttgccagatgacccctatgagaaagcttgccaaaagatggtctttgagttgttt
tctaaggtaccacctttgttattaagctttcttagaaggcaaaataaggaagactgctct
ggcctgaaagaagaattgcataaagaattcagcaagctagaggaggttctgactaataag
aagacaaccttctttggtggcagttctctttctatgattgattacctcatctggccctgg
tttgaatggctggtagccctggagttaaatgagtatgtaaaccacactccaaatcttaag
ctctggatggaagccatgatgaaagatcctgcagtatcatccctcttcattgatccaaaa
gcctttcgaggtttcttagatctctacttgcagaacaacctcgaggcctgtgactatggg
ctctga

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