Pteropus alecto (black flying fox): 102895590 Help Entry 102895590         CDS       T02993                                  Gene name KRAS Definition (RefSeq) GTPase KRas isoform X1   KO K07827   GTPase KRas Organism pale  Pteropus alecto (black flying fox) Pathway pale01521   EGFR tyrosine kinase inhibitor resistance pale01522   Endocrine resistance pale04010   MAPK signaling pathway pale04012   ErbB signaling pathway pale04014   Ras signaling pathway pale04015   Rap1 signaling pathway pale04062   Chemokine signaling pathway pale04068   FoxO signaling pathway pale04071   Sphingolipid signaling pathway pale04072   Phospholipase D signaling pathway pale04137   Mitophagy - animal pale04140   Autophagy - animal pale04150   mTOR signaling pathway pale04151   PI3K-Akt signaling pathway pale04210   Apoptosis pale04211   Longevity regulating pathway pale04213   Longevity regulating pathway - multiple species pale04218   Cellular senescence pale04360   Axon guidance pale04370   VEGF signaling pathway pale04371   Apelin signaling pathway pale04540   Gap junction pale04550   Signaling pathways regulating pluripotency of stem cells pale04625   C-type lectin receptor signaling pathway pale04650   Natural killer cell mediated cytotoxicity pale04660   T cell receptor signaling pathway pale04662   B cell receptor signaling pathway pale04664   Fc epsilon RI signaling pathway pale04714   Thermogenesis pale04720   Long-term potentiation pale04722   Neurotrophin signaling pathway pale04725   Cholinergic synapse pale04726   Serotonergic synapse pale04730   Long-term depression pale04810   Regulation of actin cytoskeleton pale04910   Insulin signaling pathway pale04912   GnRH signaling pathway pale04914   Progesterone-mediated oocyte maturation pale04915   Estrogen signaling pathway pale04916   Melanogenesis pale04917   Prolactin signaling pathway pale04919   Thyroid hormone signaling pathway pale04921   Oxytocin signaling pathway pale04926   Relaxin signaling pathway pale04929   GnRH secretion pale04933   AGE-RAGE signaling pathway in diabetic complications pale04935   Growth hormone synthesis, secretion and action pale04960   Aldosterone-regulated sodium reabsorption pale05010   Alzheimer disease pale05022   Pathways of neurodegeneration - multiple diseases pale05034   Alcoholism pale05160   Hepatitis C pale05161   Hepatitis B pale05163   Human cytomegalovirus infection pale05165   Human papillomavirus infection pale05166   Human T-cell leukemia virus 1 infection pale05167   Kaposi sarcoma-associated herpesvirus infection pale05170   Human immunodeficiency virus 1 infection pale05200   Pathways in cancer pale05203   Viral carcinogenesis pale05205   Proteoglycans in cancer pale05206   MicroRNAs in cancer pale05210   Colorectal cancer pale05211   Renal cell carcinoma pale05212   Pancreatic cancer pale05213   Endometrial cancer pale05214   Glioma pale05215   Prostate cancer pale05216   Thyroid cancer pale05218   Melanoma pale05219   Bladder cancer pale05220   Chronic myeloid leukemia pale05221   Acute myeloid leukemia pale05223   Non-small cell lung cancer pale05224   Breast cancer pale05225   Hepatocellular carcinoma pale05226   Gastric cancer pale05230   Central carbon metabolism in cancer pale05231   Choline metabolism in cancer pale05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:pale00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102895590 (KRAS)    04012 ErbB signaling pathway     102895590 (KRAS)    04014 Ras signaling pathway     102895590 (KRAS)    04015 Rap1 signaling pathway     102895590 (KRAS)    04370 VEGF signaling pathway     102895590 (KRAS)    04371 Apelin signaling pathway     102895590 (KRAS)    04068 FoxO signaling pathway     102895590 (KRAS)    04072 Phospholipase D signaling pathway     102895590 (KRAS)    04071 Sphingolipid signaling pathway     102895590 (KRAS)    04151 PI3K-Akt signaling pathway     102895590 (KRAS)    04150 mTOR signaling pathway     102895590 (KRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102895590 (KRAS)    04137 Mitophagy - animal     102895590 (KRAS)   09143 Cell growth and death    04210 Apoptosis     102895590 (KRAS)    04218 Cellular senescence     102895590 (KRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     102895590 (KRAS)    04550 Signaling pathways regulating pluripotency of stem cells     102895590 (KRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     102895590 (KRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     102895590 (KRAS)    04650 Natural killer cell mediated cytotoxicity     102895590 (KRAS)    04660 T cell receptor signaling pathway     102895590 (KRAS)    04662 B cell receptor signaling pathway     102895590 (KRAS)    04664 Fc epsilon RI signaling pathway     102895590 (KRAS)    04062 Chemokine signaling pathway     102895590 (KRAS)   09152 Endocrine system    04910 Insulin signaling pathway     102895590 (KRAS)    04929 GnRH secretion     102895590 (KRAS)    04912 GnRH signaling pathway     102895590 (KRAS)    04915 Estrogen signaling pathway     102895590 (KRAS)    04914 Progesterone-mediated oocyte maturation     102895590 (KRAS)    04917 Prolactin signaling pathway     102895590 (KRAS)    04921 Oxytocin signaling pathway     102895590 (KRAS)    04926 Relaxin signaling pathway     102895590 (KRAS)    04935 Growth hormone synthesis, secretion and action     102895590 (KRAS)    04919 Thyroid hormone signaling pathway     102895590 (KRAS)    04916 Melanogenesis     102895590 (KRAS)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102895590 (KRAS)   09156 Nervous system    04725 Cholinergic synapse     102895590 (KRAS)    04726 Serotonergic synapse     102895590 (KRAS)    04720 Long-term potentiation     102895590 (KRAS)    04730 Long-term depression     102895590 (KRAS)    04722 Neurotrophin signaling pathway     102895590 (KRAS)   09158 Development and regeneration    04360 Axon guidance     102895590 (KRAS)   09149 Aging    04211 Longevity regulating pathway     102895590 (KRAS)    04213 Longevity regulating pathway - multiple species     102895590 (KRAS)   09159 Environmental adaptation    04714 Thermogenesis     102895590 (KRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102895590 (KRAS)    05206 MicroRNAs in cancer     102895590 (KRAS)    05205 Proteoglycans in cancer     102895590 (KRAS)    05203 Viral carcinogenesis     102895590 (KRAS)    05230 Central carbon metabolism in cancer     102895590 (KRAS)    05231 Choline metabolism in cancer     102895590 (KRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102895590 (KRAS)   09162 Cancer: specific types    05210 Colorectal cancer     102895590 (KRAS)    05212 Pancreatic cancer     102895590 (KRAS)    05225 Hepatocellular carcinoma     102895590 (KRAS)    05226 Gastric cancer     102895590 (KRAS)    05214 Glioma     102895590 (KRAS)    05216 Thyroid cancer     102895590 (KRAS)    05221 Acute myeloid leukemia     102895590 (KRAS)    05220 Chronic myeloid leukemia     102895590 (KRAS)    05218 Melanoma     102895590 (KRAS)    05211 Renal cell carcinoma     102895590 (KRAS)    05219 Bladder cancer     102895590 (KRAS)    05215 Prostate cancer     102895590 (KRAS)    05213 Endometrial cancer     102895590 (KRAS)    05224 Breast cancer     102895590 (KRAS)    05223 Non-small cell lung cancer     102895590 (KRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     102895590 (KRAS)    05022 Pathways of neurodegeneration - multiple diseases     102895590 (KRAS)   09165 Substance dependence    05034 Alcoholism     102895590 (KRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     102895590 (KRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102895590 (KRAS)    05170 Human immunodeficiency virus 1 infection     102895590 (KRAS)    05161 Hepatitis B     102895590 (KRAS)    05160 Hepatitis C     102895590 (KRAS)    05163 Human cytomegalovirus infection     102895590 (KRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     102895590 (KRAS)    05165 Human papillomavirus infection     102895590 (KRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102895590 (KRAS)    01522 Endocrine resistance     102895590 (KRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pale04131]     102895590 (KRAS)   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:pale04031]     102895590 (KRAS) Membrane trafficking [BR:pale04131]  Endocytosis   Macropinocytosis    Ras GTPases     102895590 (KRAS) GTP-binding proteins [BR:pale04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     102895590 (KRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 MeaB FeoB_N G-alpha ATP_bind_1 Septin NPR1_interact AAA_25 Motif Other DBs NCBI-GeneID:  102895590 NCBI-ProteinID:  XP_006912757 LinkDB All DBs Position Unknown AA seq 188 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK SKTKCIIM NT seq 567 nt NT seq  +upstreamnt  +downstreamnt atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg atacagctaattcagaatcactttgtggatgaatatgatcctacgatagaggattcctac agaaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaata aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg ccttctagaacagtagatacaaaacaggctcaggacttagcaagaagttatggaattcct tttattgaaacatcagcaaagacaagacagggtgttgatgatgccttctatacattagtt cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag tcaaagacaaagtgtataattatgtaa

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