KEGG   Pteropus alecto (black flying fox): 102895590
Entry
102895590         CDS       T02993                                 

Gene name
KRAS
Definition
(RefSeq) GTPase KRas isoform X1
  KO
K07827  GTPase KRas
Organism
pale  Pteropus alecto (black flying fox)
Pathway
pale01521  EGFR tyrosine kinase inhibitor resistance
pale01522  Endocrine resistance
pale04010  MAPK signaling pathway
pale04012  ErbB signaling pathway
pale04014  Ras signaling pathway
pale04015  Rap1 signaling pathway
pale04062  Chemokine signaling pathway
pale04068  FoxO signaling pathway
pale04071  Sphingolipid signaling pathway
pale04072  Phospholipase D signaling pathway
pale04137  Mitophagy - animal
pale04140  Autophagy - animal
pale04150  mTOR signaling pathway
pale04151  PI3K-Akt signaling pathway
pale04210  Apoptosis
pale04211  Longevity regulating pathway
pale04213  Longevity regulating pathway - multiple species
pale04218  Cellular senescence
pale04360  Axon guidance
pale04370  VEGF signaling pathway
pale04371  Apelin signaling pathway
pale04540  Gap junction
pale04550  Signaling pathways regulating pluripotency of stem cells
pale04625  C-type lectin receptor signaling pathway
pale04650  Natural killer cell mediated cytotoxicity
pale04660  T cell receptor signaling pathway
pale04662  B cell receptor signaling pathway
pale04664  Fc epsilon RI signaling pathway
pale04714  Thermogenesis
pale04720  Long-term potentiation
pale04722  Neurotrophin signaling pathway
pale04725  Cholinergic synapse
pale04726  Serotonergic synapse
pale04730  Long-term depression
pale04810  Regulation of actin cytoskeleton
pale04910  Insulin signaling pathway
pale04912  GnRH signaling pathway
pale04914  Progesterone-mediated oocyte maturation
pale04915  Estrogen signaling pathway
pale04916  Melanogenesis
pale04917  Prolactin signaling pathway
pale04919  Thyroid hormone signaling pathway
pale04921  Oxytocin signaling pathway
pale04926  Relaxin signaling pathway
pale04929  GnRH secretion
pale04933  AGE-RAGE signaling pathway in diabetic complications
pale04935  Growth hormone synthesis, secretion and action
pale04960  Aldosterone-regulated sodium reabsorption
pale05010  Alzheimer disease
pale05022  Pathways of neurodegeneration - multiple diseases
pale05034  Alcoholism
pale05160  Hepatitis C
pale05161  Hepatitis B
pale05163  Human cytomegalovirus infection
pale05165  Human papillomavirus infection
pale05166  Human T-cell leukemia virus 1 infection
pale05167  Kaposi sarcoma-associated herpesvirus infection
pale05170  Human immunodeficiency virus 1 infection
pale05200  Pathways in cancer
pale05203  Viral carcinogenesis
pale05205  Proteoglycans in cancer
pale05206  MicroRNAs in cancer
pale05210  Colorectal cancer
pale05211  Renal cell carcinoma
pale05212  Pancreatic cancer
pale05213  Endometrial cancer
pale05214  Glioma
pale05215  Prostate cancer
pale05216  Thyroid cancer
pale05218  Melanoma
pale05219  Bladder cancer
pale05220  Chronic myeloid leukemia
pale05221  Acute myeloid leukemia
pale05223  Non-small cell lung cancer
pale05224  Breast cancer
pale05225  Hepatocellular carcinoma
pale05226  Gastric cancer
pale05230  Central carbon metabolism in cancer
pale05231  Choline metabolism in cancer
pale05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pale00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102895590 (KRAS)
   04012 ErbB signaling pathway
    102895590 (KRAS)
   04014 Ras signaling pathway
    102895590 (KRAS)
   04015 Rap1 signaling pathway
    102895590 (KRAS)
   04370 VEGF signaling pathway
    102895590 (KRAS)
   04371 Apelin signaling pathway
    102895590 (KRAS)
   04068 FoxO signaling pathway
    102895590 (KRAS)
   04072 Phospholipase D signaling pathway
    102895590 (KRAS)
   04071 Sphingolipid signaling pathway
    102895590 (KRAS)
   04151 PI3K-Akt signaling pathway
    102895590 (KRAS)
   04150 mTOR signaling pathway
    102895590 (KRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102895590 (KRAS)
   04137 Mitophagy - animal
    102895590 (KRAS)
  09143 Cell growth and death
   04210 Apoptosis
    102895590 (KRAS)
   04218 Cellular senescence
    102895590 (KRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102895590 (KRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    102895590 (KRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102895590 (KRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    102895590 (KRAS)
   04650 Natural killer cell mediated cytotoxicity
    102895590 (KRAS)
   04660 T cell receptor signaling pathway
    102895590 (KRAS)
   04662 B cell receptor signaling pathway
    102895590 (KRAS)
   04664 Fc epsilon RI signaling pathway
    102895590 (KRAS)
   04062 Chemokine signaling pathway
    102895590 (KRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102895590 (KRAS)
   04929 GnRH secretion
    102895590 (KRAS)
   04912 GnRH signaling pathway
    102895590 (KRAS)
   04915 Estrogen signaling pathway
    102895590 (KRAS)
   04914 Progesterone-mediated oocyte maturation
    102895590 (KRAS)
   04917 Prolactin signaling pathway
    102895590 (KRAS)
   04921 Oxytocin signaling pathway
    102895590 (KRAS)
   04926 Relaxin signaling pathway
    102895590 (KRAS)
   04935 Growth hormone synthesis, secretion and action
    102895590 (KRAS)
   04919 Thyroid hormone signaling pathway
    102895590 (KRAS)
   04916 Melanogenesis
    102895590 (KRAS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102895590 (KRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    102895590 (KRAS)
   04726 Serotonergic synapse
    102895590 (KRAS)
   04720 Long-term potentiation
    102895590 (KRAS)
   04730 Long-term depression
    102895590 (KRAS)
   04722 Neurotrophin signaling pathway
    102895590 (KRAS)
  09158 Development and regeneration
   04360 Axon guidance
    102895590 (KRAS)
  09149 Aging
   04211 Longevity regulating pathway
    102895590 (KRAS)
   04213 Longevity regulating pathway - multiple species
    102895590 (KRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    102895590 (KRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102895590 (KRAS)
   05206 MicroRNAs in cancer
    102895590 (KRAS)
   05205 Proteoglycans in cancer
    102895590 (KRAS)
   05203 Viral carcinogenesis
    102895590 (KRAS)
   05230 Central carbon metabolism in cancer
    102895590 (KRAS)
   05231 Choline metabolism in cancer
    102895590 (KRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102895590 (KRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102895590 (KRAS)
   05212 Pancreatic cancer
    102895590 (KRAS)
   05225 Hepatocellular carcinoma
    102895590 (KRAS)
   05226 Gastric cancer
    102895590 (KRAS)
   05214 Glioma
    102895590 (KRAS)
   05216 Thyroid cancer
    102895590 (KRAS)
   05221 Acute myeloid leukemia
    102895590 (KRAS)
   05220 Chronic myeloid leukemia
    102895590 (KRAS)
   05218 Melanoma
    102895590 (KRAS)
   05211 Renal cell carcinoma
    102895590 (KRAS)
   05219 Bladder cancer
    102895590 (KRAS)
   05215 Prostate cancer
    102895590 (KRAS)
   05213 Endometrial cancer
    102895590 (KRAS)
   05224 Breast cancer
    102895590 (KRAS)
   05223 Non-small cell lung cancer
    102895590 (KRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102895590 (KRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    102895590 (KRAS)
  09165 Substance dependence
   05034 Alcoholism
    102895590 (KRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102895590 (KRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102895590 (KRAS)
   05170 Human immunodeficiency virus 1 infection
    102895590 (KRAS)
   05161 Hepatitis B
    102895590 (KRAS)
   05160 Hepatitis C
    102895590 (KRAS)
   05163 Human cytomegalovirus infection
    102895590 (KRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102895590 (KRAS)
   05165 Human papillomavirus infection
    102895590 (KRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102895590 (KRAS)
   01522 Endocrine resistance
    102895590 (KRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pale04131]
    102895590 (KRAS)
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:pale04031]
    102895590 (KRAS)
Membrane trafficking [BR:pale04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    102895590 (KRAS)
GTP-binding proteins [BR:pale04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    102895590 (KRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 MeaB FeoB_N G-alpha ATP_bind_1 Septin NPR1_interact AAA_25
Other DBs
NCBI-GeneID: 102895590
NCBI-ProteinID: XP_006912757
LinkDB
Position
Unknown
AA seq 188 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK
SKTKCIIM
NT seq 567 nt   +upstreamnt  +downstreamnt
atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg
atacagctaattcagaatcactttgtggatgaatatgatcctacgatagaggattcctac
agaaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt
caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt
gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaata
aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg
ccttctagaacagtagatacaaaacaggctcaggacttagcaagaagttatggaattcct
tttattgaaacatcagcaaagacaagacagggtgttgatgatgccttctatacattagtt
cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag
tcaaagacaaagtgtataattatgtaa

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