KEGG   Phyllostomus discolor (pale spear-nosed bat): 114493876
Entry
114493876         CDS       T07739                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01522  Endocrine resistance
pdic04010  MAPK signaling pathway
pdic04015  Rap1 signaling pathway
pdic04068  FoxO signaling pathway
pdic04071  Sphingolipid signaling pathway
pdic04114  Oocyte meiosis
pdic04148  Efferocytosis
pdic04218  Cellular senescence
pdic04261  Adrenergic signaling in cardiomyocytes
pdic04370  VEGF signaling pathway
pdic04380  Osteoclast differentiation
pdic04550  Signaling pathways regulating pluripotency of stem cells
pdic04611  Platelet activation
pdic04613  Neutrophil extracellular trap formation
pdic04620  Toll-like receptor signaling pathway
pdic04621  NOD-like receptor signaling pathway
pdic04622  RIG-I-like receptor signaling pathway
pdic04625  C-type lectin receptor signaling pathway
pdic04657  IL-17 signaling pathway
pdic04658  Th1 and Th2 cell differentiation
pdic04659  Th17 cell differentiation
pdic04660  T cell receptor signaling pathway
pdic04664  Fc epsilon RI signaling pathway
pdic04668  TNF signaling pathway
pdic04670  Leukocyte transendothelial migration
pdic04714  Thermogenesis
pdic04722  Neurotrophin signaling pathway
pdic04723  Retrograde endocannabinoid signaling
pdic04728  Dopaminergic synapse
pdic04750  Inflammatory mediator regulation of TRP channels
pdic04912  GnRH signaling pathway
pdic04914  Progesterone-mediated oocyte maturation
pdic04917  Prolactin signaling pathway
pdic04926  Relaxin signaling pathway
pdic04932  Non-alcoholic fatty liver disease
pdic04933  AGE-RAGE signaling pathway in diabetic complications
pdic04935  Growth hormone synthesis, secretion and action
pdic04936  Alcoholic liver disease
pdic05014  Amyotrophic lateral sclerosis
pdic05020  Prion disease
pdic05022  Pathways of neurodegeneration - multiple diseases
pdic05132  Salmonella infection
pdic05133  Pertussis
pdic05135  Yersinia infection
pdic05140  Leishmaniasis
pdic05142  Chagas disease
pdic05145  Toxoplasmosis
pdic05152  Tuberculosis
pdic05161  Hepatitis B
pdic05163  Human cytomegalovirus infection
pdic05167  Kaposi sarcoma-associated herpesvirus infection
pdic05169  Epstein-Barr virus infection
pdic05170  Human immunodeficiency virus 1 infection
pdic05171  Coronavirus disease - COVID-19
pdic05205  Proteoglycans in cancer
pdic05208  Chemical carcinogenesis - reactive oxygen species
pdic05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pdic05415  Diabetic cardiomyopathy
pdic05417  Lipid and atherosclerosis
pdic05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114493876 (MAPK14)
   04015 Rap1 signaling pathway
    114493876 (MAPK14)
   04370 VEGF signaling pathway
    114493876 (MAPK14)
   04668 TNF signaling pathway
    114493876 (MAPK14)
   04068 FoxO signaling pathway
    114493876 (MAPK14)
   04071 Sphingolipid signaling pathway
    114493876 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    114493876 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    114493876 (MAPK14)
   04218 Cellular senescence
    114493876 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    114493876 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    114493876 (MAPK14)
   04613 Neutrophil extracellular trap formation
    114493876 (MAPK14)
   04620 Toll-like receptor signaling pathway
    114493876 (MAPK14)
   04621 NOD-like receptor signaling pathway
    114493876 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    114493876 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    114493876 (MAPK14)
   04660 T cell receptor signaling pathway
    114493876 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    114493876 (MAPK14)
   04659 Th17 cell differentiation
    114493876 (MAPK14)
   04657 IL-17 signaling pathway
    114493876 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    114493876 (MAPK14)
   04670 Leukocyte transendothelial migration
    114493876 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    114493876 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    114493876 (MAPK14)
   04917 Prolactin signaling pathway
    114493876 (MAPK14)
   04926 Relaxin signaling pathway
    114493876 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    114493876 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    114493876 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    114493876 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    114493876 (MAPK14)
   04722 Neurotrophin signaling pathway
    114493876 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    114493876 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    114493876 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    114493876 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    114493876 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    114493876 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    114493876 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    114493876 (MAPK14)
   05161 Hepatitis B
    114493876 (MAPK14)
   05171 Coronavirus disease - COVID-19
    114493876 (MAPK14)
   05163 Human cytomegalovirus infection
    114493876 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114493876 (MAPK14)
   05169 Epstein-Barr virus infection
    114493876 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    114493876 (MAPK14)
   05135 Yersinia infection
    114493876 (MAPK14)
   05133 Pertussis
    114493876 (MAPK14)
   05152 Tuberculosis
    114493876 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    114493876 (MAPK14)
   05140 Leishmaniasis
    114493876 (MAPK14)
   05142 Chagas disease
    114493876 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    114493876 (MAPK14)
   05020 Prion disease
    114493876 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    114493876 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114493876 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    114493876 (MAPK14)
   05415 Diabetic cardiomyopathy
    114493876 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    114493876 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    114493876 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    114493876 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    114493876 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pdic01001]
    114493876 (MAPK14)
Enzymes [BR:pdic01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     114493876 (MAPK14)
Protein kinases [BR:pdic01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   114493876 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 114493876
NCBI-ProteinID: XP_028364433
EnsemblRapid: ENSPDIG00005006070
UniProt: A0A6J2LEA4
LinkDB
Position
4:109438017..109502084
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGADLLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggaaaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
cccgagcgttaccagaacctgtccccggtgggttccggcgcctatggctcagtgtgtgct
gcttttgacacaaaaactgggttacgtgtggccgtgaagaagctctccagaccctttcag
tccattatccatgccaaaaggacctacagagaactgcgcttacttaaacatatgaaacac
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtacctggtgacccatctcatgggggcagatctgaacaacatcgtgaagtgtcag
aagctcacggacgaccacgttcagttcctcatctaccagattcttcgaggtctcaagtat
atacactcagccgacataatccacagggacctgaaacccagcaacctggctgtgaacgaa
gactgtgagctgaagatcttggattttggactggctcgacatacagatgatgaaatgaca
ggctatgtggccaccaggtggtacagagcccctgaaatcatgctgaactggatgcattac
aaccagacagttgacatttggtcggtgggatgcataatggccgagctgttgactggaaga
acgttgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgatcttttgaagaaaatctcctcagagtctgctagaaactacattcag
tctttgacccagatgccgaagatgaactttgcaaatgtttttattggtgccaatcccttg
gctgtcgacttgctggagaagatgctggtgttggactcggacaagagaatcacagcagcc
caagccctcgcgcacgcctacttcgctcagtaccacgaccccgacgatgagcccgtggcc
gatccttacgatcagtcctttgagagcagggatctccttatagatgaatggaaaagcctg
acctacgatgaagtcatcagctttgtgcctccaccccttgaccaagaagagatggagtcc
tga

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