Pongo abelii (Sumatran orangutan): 100171913 Help Entry 100171913         CDS       T01416                                  Gene name ITGB6 Definition (RefSeq) integrin beta-6   KO K06589   integrin beta 6 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04151   PI3K-Akt signaling pathway pon04510   Focal adhesion pon04512   ECM-receptor interaction pon04810   Regulation of actin cytoskeleton pon05165   Human papillomavirus infection pon05410   Hypertrophic cardiomyopathy pon05412   Arrhythmogenic right ventricular cardiomyopathy pon05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     100171913 (ITGB6)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     100171913 (ITGB6)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100171913 (ITGB6)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100171913 (ITGB6)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100171913 (ITGB6)    05412 Arrhythmogenic right ventricular cardiomyopathy     100171913 (ITGB6)    05414 Dilated cardiomyopathy     100171913 (ITGB6)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100171913 (ITGB6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pon04147]     100171913 (ITGB6)    04515 Cell adhesion molecules [BR:pon04515]     100171913 (ITGB6) Exosome [BR:pon04147]  Exosomal proteins   Exosomal proteins of epithelial cells    100171913 (ITGB6) Cell adhesion molecules [BR:pon04515]  Integrins   Integrin beta subunits    100171913 (ITGB6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Integrin_beta Integrin_b_cyt Integrin_B_tail I-EGF_1 EGF_2 Motif Other DBs NCBI-GeneID:  100171913 NCBI-ProteinID:  NP_001125033 Ensembl:  ENSPPYG00000012877 UniProt:  Q5RDL9 LinkDB All DBs Position 2B AA seq 715 aa AA seqDB search MITYKVAVPWEVQKPVKTACLLDLSVPGVLRRILPVHLELAKGGAQTLQVHVRQTEDYPV DLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEI ANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCK EKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDSKNEYSMSTVLEYPTIG QLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRS EVELEVLGDTEGLNLSFTAICNNGTLFQHQKKCSHMKVGDTASFNVTVNIPNCERRSRHI IIKPVGLGDALELLVSPECNCDCQKEVEVNSSKCHHGNGSFQCGVCACHPGHMGPRCECG EDILSTDSCKEAPDHPSCSGRGDCYCGQCICHLSPYGNIYGPYCQCDNFSCMRHKGLLCG GNGDCDCGECVCRSGWTGEYCNCTTSTDSCISEDGVLCSGRGDCVCGKCVCTNPGASGPT CERCPTCGDPCNSKRSCIECHLSAAGQAQEECVDKCKLAGATISEEEDFSKDGSVSCSLQ GENECLITFLITTDNEGKTIIHSINEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLL VSFHDRKEVAKFEAERSKVKWQTGTNPLYRGSTSTFKNVTYKHREKQKVDLSTDC NT seq 2148 nt NT seq  +upstreamnt  +downstreamnt atgatcacgtacaaggtggctgtgccctgggaggtgcagaaacctgtgaagactgcctgc ttattggacctcagtgtgcctggtgtgctcaggagaattttacccgtccatctggagttg gcgaaaggtggtgcgcagactctgcaggtgcatgtccgccagactgaggactacccggtg gatttgtattacctcatggacctctctgcctccatggatgatgacctcaacacaatcaag gagctgggctcccggctttccaaagagatgtctaaattaaccagcaactttagactgggc tttggatcttttgtagaaaaacctgtatccccttttgtgaaaacaacaccggaagaaatt gccaacccttgcagtagtattccatacttctgtttacctacatttggattcaagcatatt ttgccattgacaaatgatgctgaaagattcaatgaaattgtgaagaatcagaaaatttct gctaatattgacacacccgaaggtggatttgatgcaattatgcaagctgctgtgtgtaag gaaaaaattggctggcggaatgactccctccacctcctggtctttgtgagtgatgctgat tctcattttggaatggacagcaaactagcaggcatcgtcattcctaatgacgggctctgt cacttggacagcaagaatgaatactccatgtcaactgtcttggaatatccaacaattgga caactcattgataaactggtacaaaacaatgtgttattgatcttcgctgtaacccaagaa caagttcatttatatgagaattacgcaaaacttattcctggagctacagtagggctactt cagaaggactccggaaacattctccagctgatcatctcagcttatgaagaactgcggtct gaggtggaactggaagtattaggagacactgaaggactcaacttgtcatttacagccatc tgtaacaacggtaccctcttccaacaccaaaagaaatgctctcacatgaaagtgggagac acagcttccttcaacgtgactgtgaatatcccaaactgcgagagaagaagcaggcacatt atcataaagcctgtggggctgggggacgccctggaattacttgtcagtccagaatgcaac tgcgactgtcagaaagaagtggaagtgaacagctccaaatgtcaccatgggaacggctcc ttccagtgtggggtgtgtgcctgccaccctggccacatggggcctcgctgtgagtgtggc gaggacatactgagcacagattcctgcaaggaggccccagatcatccctcctgcagcgga aggggtgactgctactgtgggcagtgtatctgccacttgtctccctatggaaacatttat gggccttattgccagtgtgacaatttctcctgcatgagacacaaagggctgctctgcgga ggtaacggcgactgtgactgtggtgaatgtgtgtgcaggagtggctggactggcgagtac tgcaactgcaccaccagcacggactcctgcatctctgaagacggagtgctctgcagtggg cgcggggactgtgtttgtggcaagtgtgtttgcacaaaccctggagcctcaggaccaacc tgtgaacgatgtcctacctgtggtgacccctgtaactctaaacggagctgcattgaatgc cacctgtcagcagctggccaagcccaagaagaatgtgtggacaagtgcaaactagctggt gcgaccatcagtgaagaagaagatttctcaaaggatggttctgtttcctgctctctgcaa ggagaaaatgaatgtcttattacattcctaataactacagataatgaggggaaaaccatc attcacagtatcaatgaaaaagattgtccgaagcctccaaacattcccatgatcatgtta ggggtttccctggctattcttctcatcggggttgtcctactgtgcatctggaagctactg gtgtcatttcatgatcgtaaagaagttgccaaatttgaagcagaacgatcaaaagtcaag tggcaaacgggaaccaatccactctacagaggctccacaagtacttttaaaaatgtaact tataaacacagggaaaaacaaaaggtagacctttccacagattgctag

Pongo abelii (Sumatran orangutan): 100172223 Help Entry 100172223         CDS       T01416                                  Gene name ITGB1 Definition (RefSeq) integrin beta-1 precursor   KO K05719   integrin beta 1 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04015   Rap1 signaling pathway pon04145   Phagosome pon04151   PI3K-Akt signaling pathway pon04360   Axon guidance pon04510   Focal adhesion pon04512   ECM-receptor interaction pon04514   Cell adhesion molecules pon04530   Tight junction pon04611   Platelet activation pon04670   Leukocyte transendothelial migration pon04810   Regulation of actin cytoskeleton pon05100   Bacterial invasion of epithelial cells pon05133   Pertussis pon05135   Yersinia infection pon05140   Leishmaniasis pon05145   Toxoplasmosis pon05165   Human papillomavirus infection pon05200   Pathways in cancer pon05205   Proteoglycans in cancer pon05222   Small cell lung cancer pon05410   Hypertrophic cardiomyopathy pon05412   Arrhythmogenic right ventricular cardiomyopathy pon05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100172223 (ITGB1)    04151 PI3K-Akt signaling pathway     100172223 (ITGB1)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     100172223 (ITGB1)    04514 Cell adhesion molecules     100172223 (ITGB1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     100172223 (ITGB1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100172223 (ITGB1)    04530 Tight junction     100172223 (ITGB1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100172223 (ITGB1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100172223 (ITGB1)    04670 Leukocyte transendothelial migration     100172223 (ITGB1)   09158 Development and regeneration    04360 Axon guidance     100172223 (ITGB1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100172223 (ITGB1)    05205 Proteoglycans in cancer     100172223 (ITGB1)   09162 Cancer: specific types    05222 Small cell lung cancer     100172223 (ITGB1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100172223 (ITGB1)    05412 Arrhythmogenic right ventricular cardiomyopathy     100172223 (ITGB1)    05414 Dilated cardiomyopathy     100172223 (ITGB1)   09171 Infectious disease: bacterial    05135 Yersinia infection     100172223 (ITGB1)    05133 Pertussis     100172223 (ITGB1)    05100 Bacterial invasion of epithelial cells     100172223 (ITGB1)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100172223 (ITGB1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100172223 (ITGB1)    05140 Leishmaniasis     100172223 (ITGB1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pon04131]     100172223 (ITGB1)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pon04147]     100172223 (ITGB1)    04515 Cell adhesion molecules [BR:pon04515]     100172223 (ITGB1)    04090 CD molecules [BR:pon04090]     100172223 (ITGB1) Membrane trafficking [BR:pon04131]  Endocytosis   Phagocytosis    Integrins (complement receptors)     100172223 (ITGB1) Exosome [BR:pon04147]  Exosomal proteins   Proteins found in most exosomes    100172223 (ITGB1) Cell adhesion molecules [BR:pon04515]  Integrins   Integrin beta subunits    100172223 (ITGB1) CD molecules [BR:pon04090]  Proteins   100172223 (ITGB1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Integrin_beta Integrin_b_cyt Integrin_B_tail I-EGF_1 PSI_integrin EGF_2 Motif Other DBs NCBI-GeneID:  100172223 NCBI-ProteinID:  NP_001125324 UniProt:  Q5RCA9 LinkDB All DBs Position 10 AA seq 798 aa AA seqDB search MNLQPIFWIGLISSICCVFAQTDENRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPT SARCDDLEALKKKGCPPDDIENPRGSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLV LRLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDF RIGFGSFVEKTVMPYISTTPVKLRNPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQR ISGNLDSPEGGFDAIMQVAVCGSLIGRRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQ CHLENNMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTL SANSSNVIQLIIDAYNSLSSEVILENSKLSEGVTISYKSYCKNGVNGTGENGRKCSNISI GDEVQFEISITSNKCPKKDSDSFKIRPLGFTEEVEVILQYICECECQSEGIPESPKCHEG NGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRK RDNTNEIYSGKFCECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCE ASNGQICNGRGICECGVCKCTDPKFQGQTCEMCQTCLGVCAGHKECVQCRAFNKGEKKDT CTQECSYFNITKVESRDKLPQPVQPDPVSHCKEKDVDDCWFYFTYSVNGNNEVMVHVVEN PECPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGEN PIYKSAVTTVVNPKYEGK NT seq 2397 nt NT seq  +upstreamnt  +downstreamnt atgaatttacaaccgattttctggattggactgatcagttcaatttgctgtgtgtttgct caaacagatgaaaatagatgtttaaaagcaaatgccaaatcatgtggagaatgtatacaa gcagggccaaattgtgggtggtgcacaaattcaacatttttacaggaaggaatgcctact tctgcacgctgtgatgatttagaagccttaaaaaagaagggttgtcctccagatgacata gaaaatcccagaggctccaaagatataaagaaaaataaaaatgtaaccaaccgtagcaaa ggaacagcagagaagctcaagccagaggatattactcagatccaaccacagcagttggtt ttgcgattaagatcaggggagccacagacatttacattaaaattcaagagagctgaagac tatcccattgacctctactaccttatggacctgtcttactcaatgaaagacgatttggag aatgtaaaaagtcttggaacagatctgatgaatgaaatgaggaggattacttcggacttc agaattggatttggctcatttgtggaaaagactgtgatgccttacattagcacaacacca gttaagctcaggaacccttgcacaagtgaacagaactgcaccagcccatttagctacaaa aatgtgctcagtcttactaataaaggagaagtatttaatgaacttgttggaaaacagcgc atatctggaaatttggattctccagaaggtggttttgatgccatcatgcaagttgcagtt tgtggatcactgattggccggaggaatgttacacggctgctggtgttttccacagatgcc gggtttcactttgctggagatgggaaacttggtggcattgttttaccaaatgatggacaa tgtcacctggaaaataatatgtacacaatgagccattattatgattatccttctattgct caccttgtccagaaactgagtgaaaataatattcagacgatttttgcagttactgaagaa tttcagcctgtttacaaggagctgaaaaacttgatccctaagtcagcagtaggaacatta tctgcaaattctagcaatgtaattcagttgatcattgatgcatacaattccctttcctca gaagtcattttggaaaacagcaaattgtcagaaggagtaacaataagttacaaatcttac tgcaagaacggggtgaatggaacaggggaaaatggaagaaaatgttccaatatttccatt ggagatgaggttcaatttgaaattagcataacttcaaataagtgtccaaaaaaggattct gacagctttaaaattaggcctctgggctttacggaggaagtagaggttattcttcagtac atctgtgaatgtgaatgccaaagcgaaggcatccctgaaagtcccaagtgtcatgaagga aacgggacatttgagtgtggagcgtgcaggtgcaatgaagggcgtgttggtagacattgt gaatgcagcacagatgaagttaacagtgaagacatggacgcttactgcaggaaagaaaac agttcagaaatctgcagtaacaatggagagtgcgtctgcggacagtgtgtttgtaggaag agggacaatacaaatgaaatttattctggcaaattctgcgagtgtgataatttcaactgt gatagatccaatggcttaatttgtggaggaaatggtgtttgcaagtgtcgtgtgtgtgag tgcaaccccaactacactggcagtgcatgtgactgttctttggatactagtacttgtgaa gccagcaacggacagatctgcaatggccggggcatctgcgagtgtggtgtctgtaagtgt acagatccgaagtttcaagggcaaacgtgtgagatgtgtcagacctgccttggtgtctgt gctgggcataaagaatgtgttcagtgcagagccttcaataaaggagaaaagaaagacaca tgcacacaggaatgttcctattttaacattaccaaggtagaaagtcgggacaaattaccc cagccagtccaacctgatcctgtgtcccattgtaaggagaaggatgttgacgactgttgg ttctattttacgtattcagtgaatgggaacaacgaggtcatggttcatgttgtggagaat ccagagtgtcccactggtccagacatcattccaattgtagctggtgtggttgctggaatt gttcttattggccttgcattactgctgatatggaagcttttaatgataattcatgacaga agggagtttgctaaatttgaaaaggagaaaatgaatgccaaatgggacacgggtgaaaat cctatttataagagtgccgtgacaactgtggtcaatccaaagtatgagggaaaatga

Pongo abelii (Sumatran orangutan): 100440010 Help Entry 100440010         CDS       T01416                                  Gene name ITGB7 Definition (RefSeq) integrin beta-7   KO K06590   integrin beta 7 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04151   PI3K-Akt signaling pathway pon04510   Focal adhesion pon04512   ECM-receptor interaction pon04514   Cell adhesion molecules pon04672   Intestinal immune network for IgA production pon04810   Regulation of actin cytoskeleton pon05165   Human papillomavirus infection pon05202   Transcriptional misregulation in cancer pon05410   Hypertrophic cardiomyopathy pon05412   Arrhythmogenic right ventricular cardiomyopathy pon05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     100440010 (ITGB7)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     100440010 (ITGB7)    04514 Cell adhesion molecules     100440010 (ITGB7)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100440010 (ITGB7)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100440010 (ITGB7)  09150 Organismal Systems   09151 Immune system    04672 Intestinal immune network for IgA production     100440010 (ITGB7)  09160 Human Diseases   09161 Cancer: overview    05202 Transcriptional misregulation in cancer     100440010 (ITGB7)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100440010 (ITGB7)    05412 Arrhythmogenic right ventricular cardiomyopathy     100440010 (ITGB7)    05414 Dilated cardiomyopathy     100440010 (ITGB7)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100440010 (ITGB7)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pon04147]     100440010 (ITGB7)    04515 Cell adhesion molecules [BR:pon04515]     100440010 (ITGB7) Exosome [BR:pon04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    100440010 (ITGB7) Cell adhesion molecules [BR:pon04515]  Integrins   Integrin beta subunits    100440010 (ITGB7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Integrin_beta Integrin_b_cyt PSI_integrin EGF_2 I-EGF_1 Motif Other DBs NCBI-GeneID:  100440010 NCBI-ProteinID:  XP_024112442 Ensembl:  ENSPPYG00000004571 LinkDB All DBs Position 12 AA seq 798 aa AA seqDB search MVTLPVVLVLLLVLSRGESELDAKIPSTGDATERRNPHLSLLGSCQPASSCQKCILSHPS CAWCKQLNFTALGEAEARRCARREELLARGCPLEELEEPRGQQEVLQDQPLSQGARGEGA TQLAPQRVRVTLRPGEPQQLQVRFLRAEGYPVDLYYLMDLSYSMKDDLERVRQLGHALLV GLQEVTHSVRIGFGSFVDKTVLPFVSTVPSKLRHPCPTRLERCQSPFSFHHVLSLTGDAQ AFEREVGRQSVSGNLDSPEGGFDAILQAALCQEQIGWRNVSRLLVFTSDDTFHTAGDGKL GGIFMPSDGHCHLDSNGLYSRSTEFDYPSVGQVAQALSAANIQPIFAVTSAALPVYQELS KLIPKSAVGELSEDSSNVVQLIMDAYNSLSSTVTLEHSSLPPGVHISYESQCEGPEKREG KAEDRGQCNHVRINQTVTFWVSLQATHCLPEPHLLRLRALGFSEELIVELHTLCDCNCSD TQSQAPHCSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGK GHCQCGRCSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSG DMDSCISPEGELCSGHGRCKCNRCQCSDGYYGALCDQCPGCKTPCERHRDCAECGAFGTG PLATNCSTACAHTNVTLALAPILDDGWCKERTLDNQLFFFLVEDDARGRVVLRVRPQEKG ADHTQAIVLGCVGGIVAVGLGLVLAYRLSVEIYDRREYSRFEKEQQQLNWKQDSNPLYKS AITTTINPRFQEADSPTL NT seq 2397 nt NT seq  +upstreamnt  +downstreamnt atggtgactttgccagtggtccttgttttgctgctggtcctgagcagaggtgagagtgaa ttggatgccaagatcccatccacaggggatgccacagaacggcggaatcctcacctgtcc ctgctggggtcctgccagccagcctcctcctgccagaagtgcatcctctcacaccccagc tgcgcatggtgcaagcaactgaacttcaccgcgttgggggaggcggaggcgcggcgctgc gcccgacgagaggagctgctggctcgaggctgcccgctggaggagctggaggagccccgc ggccagcaggaggtactgcaggaccagccgctcagccagggcgcccgcggagagggtgcc acccagctggcgccgcagcgggtccgggtcacgctgcggcctggggagccccagcagctc caggtccgcttccttcgtgctgagggatacccggtggacctgtactaccttatggacctg agctactccatgaaggacgacctggaacgcgtgcgccagctcgggcacgctctgctggtc gggctgcaggaagtcacccattctgtgcgcattggttttggttcctttgtggacaaaacg gtgctgccctttgtgagcacagtaccctccaagctgcgccacccctgccccacccggctg gagcgctgccagtcacccttcagctttcaccatgtgctgtccctaacgggggacgcgcaa gccttcgagcgggaggtggggcgccagagtgtgtccggcaatctggactcccctgaaggt ggcttcgatgccattctgcaggctgcactctgccaggagcagattggctggagaaatgtg tcccggctgctggtgttcacttcagacgacacatttcatacagctggggacgggaagttg ggcggcattttcatgcccagtgatgggcactgccacttggacagcaatggcctctacagt cgcagcacagagtttgactacccttctgtgggtcaggtagcccaggccctctctgcagca aacatccagcccatctttgctgtcaccagtgccgcactgcctgtctaccaggagctcagt aagctgattcctaagtctgcagttggggagctgagtgaggactccagcaacgtggtacag ctcatcatggatgcttataatagcctgtcttccaccgtgacccttgaacactcttcactc cctcctggggtccacatttcttatgaatcccagtgtgagggtcctgagaagagggagggt aaggctgaggatcgaggacagtgcaaccacgtccgaatcaaccagacggtgactttctgg gtttctctccaagccacccactgcctcccagagccccatctcctgaggctccgggccctt ggcttctcagaggagctgattgtggagttgcacacactgtgtgactgtaattgcagtgac acccagtcccaggctccccactgcagtgatggccagggacacctacaatgtggggtatgc agctgtgcccctggccgcctaggtcggctctgtgagtgctctgtggctgagctgtcctcc ccagacctggaatctgggtgccgggctcccaatggcacagggcccctgtgcagtggaaag ggtcactgtcaatgtggacgctgcagctgcagtggacagagttctgggcatctgtgcgag tgtgacgatgccagctgtgagcgacatgagggcatcctctgtggaggctttggtcgctgc caatgtggagtatgtcactgtcatgccaaccgcacgggcagagcatgcgaatgcagtggg gacatggacagttgcatcagtcccgagggagagctctgcagtgggcatggacgctgcaaa tgcaaccgctgccagtgctcggacggttactatggtgctctatgcgaccaatgcccaggc tgcaagacaccatgtgagagacaccgggactgtgcagagtgtggggccttcgggactggc ccactggccaccaactgcagtacagcttgtgcccataccaatgtgaccctggccttggcc cctatcttggatgatggctggtgcaaagagaggaccctggacaaccagctgttcttcttc ttggtggaggatgatgccagaggcagggttgtgctcagagtgagaccccaagaaaaggga gcagaccacacccaggccattgtgctgggttgcgtagggggcatcgtggcagtggggctg gggctggtcctggcttaccggctctcggtggaaatctatgaccgccgggaatacagtcgc tttgagaaggagcagcaacaactcaactggaagcaggacagtaatcctctctacaaaagt gccatcacgaccaccatcaatcctcgctttcaagaggcagacagtcccactctctga

Pongo abelii (Sumatran orangutan): 100445345 Help Entry 100445345         CDS       T01416                                  Gene name ITGB3 Definition (RefSeq) integrin beta-3   KO K06493   integrin beta 3 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04015   Rap1 signaling pathway pon04145   Phagosome pon04151   PI3K-Akt signaling pathway pon04380   Osteoclast differentiation pon04510   Focal adhesion pon04512   ECM-receptor interaction pon04611   Platelet activation pon04613   Neutrophil extracellular trap formation pon04640   Hematopoietic cell lineage pon04810   Regulation of actin cytoskeleton pon04919   Thyroid hormone signaling pathway pon05163   Human cytomegalovirus infection pon05165   Human papillomavirus infection pon05168   Herpes simplex virus 1 infection pon05205   Proteoglycans in cancer pon05206   MicroRNAs in cancer pon05410   Hypertrophic cardiomyopathy pon05412   Arrhythmogenic right ventricular cardiomyopathy pon05414   Dilated cardiomyopathy pon05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100445345 (ITGB3)    04151 PI3K-Akt signaling pathway     100445345 (ITGB3)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     100445345 (ITGB3)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     100445345 (ITGB3)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100445345 (ITGB3)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100445345 (ITGB3)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     100445345 (ITGB3)    04611 Platelet activation     100445345 (ITGB3)    04613 Neutrophil extracellular trap formation     100445345 (ITGB3)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     100445345 (ITGB3)   09158 Development and regeneration    04380 Osteoclast differentiation     100445345 (ITGB3)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     100445345 (ITGB3)    05205 Proteoglycans in cancer     100445345 (ITGB3)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     100445345 (ITGB3)    05410 Hypertrophic cardiomyopathy     100445345 (ITGB3)    05412 Arrhythmogenic right ventricular cardiomyopathy     100445345 (ITGB3)    05414 Dilated cardiomyopathy     100445345 (ITGB3)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     100445345 (ITGB3)    05163 Human cytomegalovirus infection     100445345 (ITGB3)    05165 Human papillomavirus infection     100445345 (ITGB3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pon04131]     100445345 (ITGB3)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pon04147]     100445345 (ITGB3)    04515 Cell adhesion molecules [BR:pon04515]     100445345 (ITGB3)    04090 CD molecules [BR:pon04090]     100445345 (ITGB3) Membrane trafficking [BR:pon04131]  Endocytosis   Phagocytosis    Integrins (complement receptors)     100445345 (ITGB3) Exosome [BR:pon04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    100445345 (ITGB3) Cell adhesion molecules [BR:pon04515]  Integrins   Integrin beta subunits    100445345 (ITGB3) CD molecules [BR:pon04090]  Proteins   100445345 (ITGB3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Integrin_beta Integrin_B_tail Integrin_b_cyt I-EGF_1 PSI_integrin EGF_2 Motif Other DBs NCBI-GeneID:  100445345 NCBI-ProteinID:  XP_002834363 LinkDB All DBs Position 17 AA seq 788 aa AA seqDB search MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCHQCLAVSPMCAWCSDEALPLG SPRCDLKENLLKDNCALESIEFPVSEARVLEDRPLSNKGSGDSSQVTQVSPQRIALRLRP DDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFG AFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSR NRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCH VGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLS MDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDT VSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGT FECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFG KITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLL CSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRY CRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDIL VVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTF TNITYRGT NT seq 2367 nt NT seq  +upstreamnt  +downstreamnt atgcgagcgcggccgcggccccggccgctctgggcgactgtgctggcgctgggggcgctg gcgggcgttggcgtcggagggcccaacatctgtaccacgcgaggtgtgagctcctgccat cagtgcctggctgtgagccccatgtgtgcctggtgctctgatgaggccctgcctctgggc tcacctcgctgtgacctgaaggagaatctgctgaaggataactgtgccctggaatccatc gagttcccagtgagtgaggcccgagtactagaggacaggcccctcagcaacaagggctct ggagacagctcccaggtcactcaagtcagtccccagaggattgcactccggctccggcca gatgattcgaagaatttctccatccaagtgcggcaggtggaggattaccctgtggacatc tactacttgatggacctgtcttactccatgaaggatgatctgtggagcatccagaacctg ggtaccaagctggccacccagatgcgaaagctcaccagtaacctgcggattggcttcggg gcatttgtggacaagcctgtgtcaccatacatgtatatctccccaccagaggccctcgaa aacccctgctatgatatgaagaccacctgcttgcccatgtttggctacaaacacgtgctg acgctcactgaccaggtgacccgcttcaatgaggaagtgaagaagcagagtgtgtcacgg aaccgagatgccccagagggtggctttgatgctatcatgcaggctacagtctgtgatgaa aagattggctggaggaatgacgcatcccacttgctggtgtttaccactgatgccaagact catatagcactggacggaaggctggcaggcattgtccagcccaatgatgggcagtgtcat gttggtagtgacaatcattactctgcctccactaccatggattatccctctttggggctg atgactgagaagctatcccagaaaaacatcaatttgatctttgcagtgactgaaaatgta gtcaatctctatcagaactatagtgagctcatcccagggaccacagtcggggttctgtcc atggattccagcaatgtcctccagctcattgtcgatgcttatgggaaaatccgctctaaa gtcgagctggaagtgcgtgacctccctgaagagttgtctctatccttcaatgccacctgc ctcaacaatgaggtcatccctggcctcaagtcttgtatgggactcaagattggagacacg gtgagcttcagcattgaggccaaagtgcgaggctgtccccaggagaaggagaagtccttt accatcaagcccgtgggcttcaaggacagcctgatcgtccaggtcacctttgattgtgac tgtgcctgccaggcccaagctgaacctaatagccatcgctgcaacaatggcaatgggacc tttgagtgtggggtatgccgttgtgggcctggctggctgggatcccagtgtgagtgctca gaggaggactatcgcccttcccagcaggacgagtgcagcccccgggagggtcagcccgtc tgcagccagcggggcgagtgcctctgtggtcagtgtgtctgccacagcagtgactttggc aagatcacgggcaagtactgcgagtgtgatgacttctcctgtgtccgctacaagggggag atgtgctcaggccatggccagtgcagctgtggggactgcctgtgtgactctgactggacc ggctactactgcaactgtaccacacgtactgacacctgcatgtccagcaatgggctgctg tgcagcggccgcggcaagtgtgaatgtggcagctgtgtctgtatccagccaggctcctat ggggacacctgtgagaagtgccccacctgcccagatgcctgcacctttaagaaagaatgt gtggagtgtaagaagtttgatcggggagccctacatgacgaaaatacctgcaaccgttac tgccgtgatgagattgagtcagtgaaagagcttaaggacactggcaaggatgcagtgaat tgtacctataagaatgaggatgactgtgtcgtcagattccagtactatgaagattctagt ggaaagtccatcctgtatgtggtagaagagccagagtgtcccaagggccctgacatcctg gtggtcctgctctcagtgatgggggccattctgctcatcggccttgccgctctgctcatc tggaagctcctcatcaccatccacgaccgaaaagagttcgctaaatttgaggaagaacgc gccagagcaaaatgggacacagccaacaacccactgtataaagaggccacatctaccttc accaatatcacgtaccggggcacttaa

Pongo abelii (Sumatran orangutan): 100449826 Help Entry 100449826         CDS       T01416                                  Gene name ITGB5 Definition (RefSeq) integrin beta-5   KO K06588   integrin beta 5 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04145   Phagosome pon04151   PI3K-Akt signaling pathway pon04510   Focal adhesion pon04512   ECM-receptor interaction pon04810   Regulation of actin cytoskeleton pon05165   Human papillomavirus infection pon05205   Proteoglycans in cancer pon05410   Hypertrophic cardiomyopathy pon05412   Arrhythmogenic right ventricular cardiomyopathy pon05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     100449826 (ITGB5)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     100449826 (ITGB5)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     100449826 (ITGB5)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100449826 (ITGB5)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100449826 (ITGB5)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     100449826 (ITGB5)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100449826 (ITGB5)    05412 Arrhythmogenic right ventricular cardiomyopathy     100449826 (ITGB5)    05414 Dilated cardiomyopathy     100449826 (ITGB5)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100449826 (ITGB5)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pon04131]     100449826 (ITGB5)   09183 Protein families: signaling and cellular processes    04515 Cell adhesion molecules [BR:pon04515]     100449826 (ITGB5) Membrane trafficking [BR:pon04131]  Endocytosis   Phagocytosis    Integrins (complement receptors)     100449826 (ITGB5) Cell adhesion molecules [BR:pon04515]  Integrins   Integrin beta subunits    100449826 (ITGB5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Integrin_beta Integrin_B_tail Integrin_b_cyt PSI_integrin I-EGF_1 EGF_2 DUF2975 Motif Other DBs NCBI-GeneID:  100449826 NCBI-ProteinID:  XP_024100765 Ensembl:  ENSPPYG00000013466 LinkDB All DBs Position 3 AA seq 799 aa AA seqDB search MPRAPAPLYACLLGLCALLPRLAGLNICTSGSASSCEECLLIHPKCSWCFKEDFGSPRSI TSRCDLRANLVRNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRP GDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFG SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEIL DGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGD TASFEVSVEARSCPSRHTEHVFSLRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCSGSG TYVCGLCECNPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEF GKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQ ICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSL CRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNA MTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST HTVDFTFNKFNKSYNGTVD NT seq 2400 nt NT seq  +upstreamnt  +downstreamnt atgccgcgggccccggcgccgctgtacgcctgcctcctggggctctgcgcgctcctgccc cggctggcaggtctcaacatatgcactagtggaagtgccagctcatgtgaagaatgtctg ctaatccacccaaaatgttcctggtgcttcaaagaggacttcggaagcccacggtccatc acctctcggtgtgacttgagggcaaaccttgtcagaaatggctgtggaggtgagatagag agcccagccagcagcttccatgtcctgaggagcctgcccctcagcagcaagggttcgggc tctgcaggctgggacgtcattcagatgacaccacaggagattgccgtgaacctccggccc ggtgacaagaccaccttccagctacaggttcgccaggtggaggactatcctgtggacctg tactacctgatggacctctccctgtccatgaaggatgacttggacaatatccggagcctg ggcaccaaactcgcggaggagatgaggaagctcaccagcaacttccgtttgggatttggg tcttttgttgataaggacatctctcctttctcctacacagcaccgaggtaccagaccaat ccatgcattggttacaagttgtttccaaattgcgtcccctcctttgggttccgccatctg ctgcctctcacagacagagtggacagcttcaatgaggaagttcggaaacagagggtgtcc cggaaccgagatgcccctgaggggggctttgatgcagtactccaggcagccgtctgcaag gagaagattggctggcgaaaggatgcactgcatttgctggtgttcacaacggatgatgtg ccccacattgcattggatggaaaattgggaggtctggtgcagccacatgatggccagtgc cacctgaacgaggccaacgagtacactgcatctaaccagatggactatccatcccttgcc ttgcttggagagaaactggcagagaacaacatcaacctcatctttgcagtgacgaaaaac cattatatgctgtacaagaattttacagccctgatacctggaacaacggtggagatttta gacggagactccaaaaatattattcaactgattattaatgcatacaatagtatccggtct aaagtggagctgtcggtctgggatcagcctgaggatcttaatctcttctttactgctacc tgccaagatggggtatcctatcctggtcagaggaagtgtgagggcctgaagattggggac acggcatcttttgaggtatcagtggaggcccgaagctgtcccagcagacacacggagcac gtgttttccctgcggccggtgggattccgggacagcctggaggtgggggtcacctacaac tgcacgtgcggctgcagcgtggggctggaacccaacagcgccaggtgcagcgggagcggg acctatgtctgcggcctgtgtgagtgcaaccccggctacctgggcaccaggtgcgagtgc caggatggggagaaccagagtgtgtaccagaacctgtgccgggaggcagagggcaagcca ctgtgcagcgggcgcggggactgcagctgcaaccagtgctcctgcttcgagagcgagttc ggcaagatctacgggcctttctgtgagtgcgacaacttctcctgtgccaggaacaaggga gtcctctgctcaggccatggcgagtgtcactgcggggaatgcaagtgccatgcaggttac atcggggacaactgtaactgctcgacagacatcagcacgtgccggggcagagatggccag atctgcagcgagcgtgggcactgtctctgtgggcagtgccaatgcacggagccgggggcc tttggggagatgtgtgagaagtgccccacctgcccggatgcgtgcagcaccaagagagat tgtgtcgagtgcctgctgctccactctgggaaacctgacaaccagacctgccacagcctg tgcagggatgaggtgatcacatgggtggacaccatcgtgaaagatgaccaggaggctgtg ctttgtttctacaaaaccgccaaggactgcgtcatgatgttcacctatgtggagctcccc agtgggaagtccaacctgacggtcctcagggagccagagtgtggaaacacccccaacgcc atgaccatcctcctggctgtggtcggtagcatcctccttgttgggctcgcactcctggct atctggaagctgcttgtcaccatccatgaccggagggagtttgcaaagttccagagcgag cgatccagggcccgctacgaaatggcttcaaacccattgtacagaaagcctatctccaca cacactgtggacttcaccttcaacaaattcaacaaatcctacaatggcactgtggactga

Pongo abelii (Sumatran orangutan): 100453768 Help Entry 100453768         CDS       T01416                                  Gene name ITGB4 Definition (RefSeq) integrin beta-4 isoform X1   KO K06525   integrin beta 4 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04151   PI3K-Akt signaling pathway pon04510   Focal adhesion pon04512   ECM-receptor interaction pon04810   Regulation of actin cytoskeleton pon05165   Human papillomavirus infection pon05410   Hypertrophic cardiomyopathy pon05412   Arrhythmogenic right ventricular cardiomyopathy pon05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     100453768 (ITGB4)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     100453768 (ITGB4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100453768 (ITGB4)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100453768 (ITGB4)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100453768 (ITGB4)    05412 Arrhythmogenic right ventricular cardiomyopathy     100453768 (ITGB4)    05414 Dilated cardiomyopathy     100453768 (ITGB4)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100453768 (ITGB4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pon04147]     100453768 (ITGB4)    04515 Cell adhesion molecules [BR:pon04515]     100453768 (ITGB4)    04090 CD molecules [BR:pon04090]     100453768 (ITGB4) Exosome [BR:pon04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    100453768 (ITGB4)   Exosomal proteins of bladder cancer cells    100453768 (ITGB4) Cell adhesion molecules [BR:pon04515]  Integrins   Integrin beta subunits    100453768 (ITGB4) CD molecules [BR:pon04090]  Proteins   100453768 (ITGB4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Integrin_beta fn3 Calx-beta Integrin_B_tail I-EGF_1 PSI_integrin Pur_ac_phosph_N EGF_2 SEA Motif Other DBs NCBI-GeneID:  100453768 NCBI-ProteinID:  XP_024091018 Ensembl:  ENSPPYG00000008634 LinkDB All DBs Position 17 AA seq 1752 aa AA seqDB search MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR CNTQAELLAAGCQRENIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEEQHFEL EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDATGTYTQYR TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTKTGSFHIRRGEVGVYQVQLRALEHVDG THVCQLPEDQKGNIHLKPSFSDGLKMDVGIICDVCTCELRKEVRSARCSFNGDFMCGHCV CSEGWSGQTCNCSTGSLSDIQPCLREDEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR SGSLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDEEKQL LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG KSQVSYRTQDGTAQGNRDYIPMEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG AEGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA FPGSTNSLHGMTTTSTAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIIGYLVTCEMAQGGGPATTF RVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSHAG LFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGT LSTQVDQQFFQT NT seq 5259 nt NT seq  +upstreamnt  +downstreamnt atggcagggccacgccccagcccatgggccaggctgctactggcagccttgatcagcgtc agcctctctgggaccttggcaaaccgctgcaagaaggccccagtgaagagctgcacggag tgtgtccgtgtggataaggactgcgcctactgcacggacgagatgttcagggaccggcgc tgcaacacccaggcggagctgctggccgcgggctgccagcgggagaacatcgtggtcatg gagagcagcttccagatcacagaggagacccagattgacaccaccctgcggcgcagccag atgtccccccagggcctgcgggtccgtctgcggcccggtgaggagcagcactttgagctg gaggtgtttgagcccctggagagccctgtggacctgtacatcctcatggacttctccaac tccatgtccgatgatctggacaacctcaagaagatggggcagaacctggctcgggtcctg agccagctcaccagcgactacactattggatttggcaagtttgtggacaaagtcagcgtc ccgcagacggacatgaggcctgagaagctgaaggagccctggcccaacagtgaccccccc ttctccttcaagaacgtcatcagcctgacagaagatgtggatgagttccggaataaactg cagggagagcggatctcaggcaacctggatgctcctgagggcggcttcgatgccatcctg cagacggccgtgtgcacgagggacattggctggcgcccagacagcacccacctgctggtc ttctccaccgagtcagccttccactatgaggccgacggcgccaacgtgctggctggcatc atgagccgcaacgatgaacggtgccacctggatgccacgggcacctacacccagtacagg acacaggactacccgtcggtgcccaccctggtgcgcctgctcgccaagcacaacatcatc cccatttttgctgtcaccaactactcctatagctactacgagaagcttcacacctatttc cctgtctcctcgctgggggtgctgcaggaggactcgtccaacatcgtggagctgctggag gaggccttcaatcgaatccgctccaacctggacatccgggccctagacagcccccgaggc cttcggacagaggtcacctccaagatgttccagaagacgaagactgggtcctttcacatc cggcggggggaagtgggtgtataccaggtgcagctgcgggccctcgagcacgtggatggg actcatgtgtgccagctgccggaggaccagaagggcaacatccatctgaaaccttccttc tccgatggcctcaagatggacgtgggcatcatctgtgacgtgtgcacctgcgagctgcga aaagaggtgcggtcagctcgctgcagcttcaacggagacttcatgtgtggacactgtgtg tgcagtgagggctggagtggccagacctgcaactgctccaccggctctctgagtgacatt cagccctgcctgcgggaggacgaggacaagccgtgctccggccgtggcgagtgccagtgc gggcactgtgtgtgctacggcgaaggccgctatgagggtcagttctgcgagtatgacaac ttccagtgtccccgcacttccgggttcctctgcaatgaccgaggacgctgctccatgggc cagtgtgtgtgtgagcctggttggacaggcccaagctgtgactgtcccctcagcaatgcc acctgcatcgacagcaatgggggcatctgcaatggacgtggccactgtgagtgtggccgc tgccactgccaccagcagtcgctctacacggacaccatctgcgagatcaactactcggcg atccacccgggcctctgcgaggacctacgctcctgcgtgcagtgccaggcgtggggcacc ggggagaagaaggggcgcacgtgtgaggaatgcaacttcaaggtcaagatggtggacgag cttaagagagccgaggaggtggtggtgcgctgctccttccgggacgaggatgacgactgc acctacagctacaccatggaaggcgacggcgcccctgggcccaacagcactgtcctggtg cacaagaagaaggactgccctccaggctccttctggtggctcatccccctgctcctcctc ctcctgccgctcctggccctgctactgctactatgctggaagtactgcgcctgctgcaag gcctgcctggcacttctcccttgctgcaaccgaggtcacatggtaggctttaaggaagac cactacatgctgcgggagaacctgatggcctcagaccacctggacacacccatgctgcgt agcgggagcctcaagggccgtgacgtggtccgctggaaggtcaccaacaacatgcaacgg cctggctttgccactcatgctgccagcatcaaccccacagagctggtgccctacgggctg tccttgcgcctggcccgcctttgcaccgagaacctgctgaagcccgacactcgggaatgc gcccagctgcgccaggaggtggaggagaacctgaacgaggtctacaggcagatctccggt gtacacaagctccagcagaccaagttccggcagcagcccaatgctgggaaaaagcaagac cacaccattgtggacacagtgctgatggcaccccgctcggccaagccggccctgctgaag cttacagagaagcaggtggaacagagggccttccacgacctcaaggtggcccctggctac tacaccctcactgcagaccaggacgcccggggcatggtggagttccaggagggcgtggag ctggtggacgtacgggtgcccctctttatccggcctgaggatgacgaggagaagcagctg ctggtggaggccatcgatgtgcccgcgggcactgccaccctcggccgccgcctggtaaac atcaccatcatcaaggagcaagccagagacgtggtgtcctttgagcagcctgagttctcg gtcagccgcggggaccaggtggcccgcatccctgtcatccggcgcgtcctggatggcggg aagtcccaggtctcctaccgcacacaggatggcaccgcgcagggcaaccgggactacatc cccatggagggcgagctgctgttccagcctggggaggcctggaaagagctgcaggtgaag ctcctggagctgcaagaggttgactccctcctgcggggccgccaggtccgccgtttccac gtccagctcagcaaccctaagtttggggcccacctgggccagccccactccaccaccatc atcatcagggacccagatgaactggaccggagcttcacgagtcagatgttgtcatcacag ccaccccctcacggcgacctgggcgccccgcagaaccccaatgctaaggccgctgggtcc aggaagatccatttcaactggctgcccccttctggcaagccaatggggtacagggtaaag tactggattcagggtgactccgagtccgaagcccacctgctcgacagcaaggtgccctca gtggagctcaccaacctgtacccgtattgcgactatgagatgaaggtgtgcgcctacggg gctgagggcgagggaccctacagctccctggtgtcctgccgcacccaccaggaagtgccc agcgagccagggcgtctggccttcaatgtcgtctcctccacggtgacccagctgagctgg gctgagccagccgagaccaacggtgagatcacagcctacgaggtctgctatggcctggtc aacgatgacaaccgacctatcgggcccatgaagaaggtgctggttgacaaccctaagaac cggatgctgctcattgagaaccttcgggagtcccagccctaccgctacacggtgaaggcg cgcaatggggccggctgggggcccgagcgggaggccatcatcaacctggcgacccagccc aagaggcccatgtccatccccatcattcctgacatccctatcgtggacgcccagagcggg gaggactacgacagcttccttatgtacagcgatgacgttctacgctctccatctggcagc cagaggcccagcgtctccgatgacactgagcacctggtgaatggccggatggactttgcc ttcccgggcagcaccaactccctgcatgggatgaccacgaccagcactgctgcctatggc acccacctgagcccacacgtgccccaccgcgtgctaagcacatcctccacccttacacgg gactacaactcgctgacccgctcggaacactcacactcgaccacactgcccagggactac tccaccctcacctccgtctcctcccacgactctcgcctgactgctggtgtgcccgacacg cccacccgcctggtgttctctgccctggggcccacatctctcagagtgagctggcaggag ccgcggtgcgagcggccgctgcagggctacagcgtggagtaccagctgctgaacggcggt gagctgcatcggctcaacatccccaaccctgcccagacctcggtggtggtagaagacctc ctgcccaaccactcctacgtgttccgcgtgcgggcccagagccaggaaggctggggccga gagcgtgagggcgtcatcaccattgaatcccaggtgcacccgcagagcccactctgtccc ctgccaggctccgccttcactttgagcactcccagtgccccaggcccactggtgttcact gccctgagcccagactcgctgcagctgagctgggagcggccacggaggcccaatggggat atcattggctacctggtgacctgtgagatggcccaaggaggagggccagccaccacattc cgggtggatggagacagccccgagagccggctgaccgtgccgggcctcagtgagaacgtg ccctacaagttcaaggtgcaggccaggaccactgaaggcttcgggccagagcgcgagggc atcatcaccatagagtcccaggatggcggacccttcccgcagctgggcagccatgccggg ctcttccagcacccgctgcaaagcgagtacagcagcatcaccaccacccacaccagcgcc accgagcccttcctagtggacgggctgaccctgggggcccagcacctagaggcaggtggc tccctcacccggcatgtgacccaggagtttgtgagccggacgctgaccaccagcggaacc ctcagcacccaggtggaccaacagttcttccaaacctga

Pongo abelii (Sumatran orangutan): 100459025 Help Entry 100459025         CDS       T01416                                  Gene name ITGB8 Definition (RefSeq) integrin beta-8   KO K06591   integrin beta 8 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04151   PI3K-Akt signaling pathway pon04510   Focal adhesion pon04512   ECM-receptor interaction pon04514   Cell adhesion molecules pon04810   Regulation of actin cytoskeleton pon05165   Human papillomavirus infection pon05410   Hypertrophic cardiomyopathy pon05412   Arrhythmogenic right ventricular cardiomyopathy pon05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     100459025 (ITGB8)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     100459025 (ITGB8)    04514 Cell adhesion molecules     100459025 (ITGB8)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100459025 (ITGB8)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100459025 (ITGB8)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100459025 (ITGB8)    05412 Arrhythmogenic right ventricular cardiomyopathy     100459025 (ITGB8)    05414 Dilated cardiomyopathy     100459025 (ITGB8)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100459025 (ITGB8)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pon04147]     100459025 (ITGB8)    04515 Cell adhesion molecules [BR:pon04515]     100459025 (ITGB8) Exosome [BR:pon04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    100459025 (ITGB8) Cell adhesion molecules [BR:pon04515]  Integrins   Integrin beta subunits    100459025 (ITGB8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Integrin_beta PSI_integrin EGF_2 Motif Other DBs NCBI-GeneID:  100459025 NCBI-ProteinID:  XP_002818218 Ensembl:  ENSPPYG00000017749 UniProt:  H2PMQ3 A0A663DDC0 LinkDB All DBs Position 7 AA seq 769 aa AA seqDB search MCGSALAFFTAAFVCLQNDRRGPASFLWAAWVFSLVLGLSQGEDNRCASSNAASCARCLA LGPECGWCVQEDFISDGSRSERCDIVSNLISKGCSVDSIEYPSVHVIIPTENEINTQVTP GEVSIQLRPGAEANFMLKVHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFF SRDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKA VHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIV VPNDGNCHLKNNVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPG TIAGEIESKAANLNNLVVEAYQKLISEVKVQVENQVQGIYLNITAICPDGSRKPGMEGCR NVTSNDEVLFNVTVTMKKCDLTGGKNYAIIKPIGFNETAKIHIHRNCSCQCEDNRGPKGK CVDETFLDSKCFQCDENKCHFDEDQFSSESCKSHKDQPVCSGRGVCVCGKCSCHKIKLGK VYGKYCEKDDFSCPYHHGNLCAGHGECEAGRCQCFSGWEGDRCQCPSAAAQHCVNSKGQV CSGRGTCVCGRCECTDPRSIGRFCEHCPTCYTACKENWNCMQCLHPHNLSQAILDQCKTS CALMEQQHYVDQTSECFSSPSYLRIFFIIFIVTFLIGLLKVLIIRQVILQWNSNKIKSSS DYRVSASKKDKLILQSVCTRAVTYRREKPEEIKMDISKLNAHETFRCNF NT seq 2310 nt NT seq  +upstreamnt  +downstreamnt atgtgcggctcggccctggctttttttaccgctgcatttgtctgcctgcaaaacgaccgg cgaggtcccgcctcgttcctctgggcagcctgggtgttttcacttgttcttggactgagc caaggtgaagacaatagatgtgcatcttcaaatgcagcatcctgtgccaggtgccttgcg ctgggtccagaatgtggatggtgtgttcaagaggatttcatttcagatggatcaagaagt gaacgttgtgatattgtttccaatttaataagcaaaggctgctcagttgattcaatagaa tacccatctgtgcatgttataatacccactgaaaatgaaattaatacccaggtgacacca ggagaagtgtctatccagctgcgtccaggagctgaagctaattttatgctgaaagttcat cctctgaagaaatatcctgtggatctttattatcttgttgatgtctcagcatcaatgcac aataatatagaaaaattaaattccgttggaaacgatttatctagaaaaatggcatttttc tcccgtgactttcgtcttggatttggctcatacgttgataaaacagtttcaccatacatt agcatccaccccgaaaggattcataatcaatgcagtgactacaatttagactgcatgcct ccccatggatacatccatgtgctgtctttgacagagaacatcactgagtttgagaaagca gttcatagacagaagatctctggaaacatagatacaccggaaggaggttttgacgccatg cttcaggcagctgtctgtgaaagtcatattggatggcgaaaagaggctaaaagattgctg ctggtgatgacagatcagacatctcatcttgctcttgatagcaaattggcaggcatagtg gtgcccaatgacggaaactgccatctgaaaaacaatgtctacgtcaaatcgacaaccatg gaacatccctcactaggccaactttcagagaaattaatagacaacaacattaatgtcatc tttgcagttcaaggaaaacaatttcattggtataaggatcttctacccctcttgccgggc accattgctggtgaaatagaatcaaaggctgcaaacctcaataatttggtagtggaagcc tatcagaagctcatttcagaagtgaaagttcaggtggaaaaccaggtacaaggcatctat ttgaacattaccgccatctgtccagatgggtccagaaagccaggcatggaaggatgcaga aatgtgacgagcaatgatgaagttcttttcaatgtaacagttacaatgaaaaaatgtgat ctcacaggaggaaaaaactatgcaataatcaaacctattggttttaatgaaaccgctaaa attcatatacacagaaactgcagctgtcagtgtgaggacaacagaggacctaaaggaaag tgtgtagatgaaacttttctagattccaagtgtttccagtgtgatgagaataaatgtcat tttgatgaagatcagttttcttctgagagttgcaagtcacacaaggatcaacctgtttgc agtggtcgaggagtttgtgtttgtggcaaatgttcatgtcacaaaattaagcttggaaaa gtgtatggaaaatactgtgaaaaggatgatttttcttgtccatatcaccatggaaatctg tgtgctgggcatggagagtgtgaagcaggcagatgccaatgcttcagtggctgggaagga gatcggtgccagtgcccttcagcagcagcccagcactgtgtcaattcaaagggccaagtg tgcagtggaagaggcacgtgtgtgtgtggaaggtgtgagtgcaccgatcccaggagcatc ggccgcttctgtgaacactgccccacctgttatacggcctgcaaggaaaattggaattgt atgcaatgccttcaccctcacaatttgtctcaggctatacttgatcagtgcaaaacctca tgtgctctcatggaacaacagcattatgtcgaccaaacttcagaatgtttctccagccca agctacttgagaatatttttcatcattttcatagttacattcttgattgggttgcttaaa gtccttatcattagacaggtgatactacaatggaatagtaacaaaattaagtcctcatca gattacagagtgtcagcctcaaaaaaggataagttgattctgcaaagtgtttgcacaaga gcagtaacctaccgacgtgagaagcctgaagaaataaaaatggatatcagcaaattaaat gctcatgaaactttcaggtgcaacttctaa

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