Pongo abelii (Sumatran orangutan): 100172156
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Entry
100172156 CDS
T01416
Gene name
IGF1R
Definition
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon01522
Endocrine resistance
pon04010
MAPK signaling pathway
pon04014
Ras signaling pathway
pon04015
Rap1 signaling pathway
pon04066
HIF-1 signaling pathway
pon04068
FoxO signaling pathway
pon04114
Oocyte meiosis
pon04140
Autophagy - animal
pon04144
Endocytosis
pon04150
mTOR signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04152
AMPK signaling pathway
pon04211
Longevity regulating pathway
pon04213
Longevity regulating pathway - multiple species
pon04510
Focal adhesion
pon04520
Adherens junction
pon04550
Signaling pathways regulating pluripotency of stem cells
pon04730
Long-term depression
pon04913
Ovarian steroidogenesis
pon04914
Progesterone-mediated oocyte maturation
pon05200
Pathways in cancer
pon05202
Transcriptional misregulation in cancer
pon05205
Proteoglycans in cancer
pon05214
Glioma
pon05215
Prostate cancer
pon05218
Melanoma
pon05224
Breast cancer
pon05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100172156 (IGF1R)
04014 Ras signaling pathway
100172156 (IGF1R)
04015 Rap1 signaling pathway
100172156 (IGF1R)
04066 HIF-1 signaling pathway
100172156 (IGF1R)
04068 FoxO signaling pathway
100172156 (IGF1R)
04151 PI3K-Akt signaling pathway
100172156 (IGF1R)
04152 AMPK signaling pathway
100172156 (IGF1R)
04150 mTOR signaling pathway
100172156 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100172156 (IGF1R)
04140 Autophagy - animal
100172156 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
100172156 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100172156 (IGF1R)
04520 Adherens junction
100172156 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
100172156 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100172156 (IGF1R)
04914 Progesterone-mediated oocyte maturation
100172156 (IGF1R)
09156 Nervous system
04730 Long-term depression
100172156 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
100172156 (IGF1R)
04213 Longevity regulating pathway - multiple species
100172156 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100172156 (IGF1R)
05202 Transcriptional misregulation in cancer
100172156 (IGF1R)
05205 Proteoglycans in cancer
100172156 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100172156 (IGF1R)
05214 Glioma
100172156 (IGF1R)
05218 Melanoma
100172156 (IGF1R)
05215 Prostate cancer
100172156 (IGF1R)
05224 Breast cancer
100172156 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100172156 (IGF1R)
01522 Endocrine resistance
100172156 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100172156 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pon04090
]
100172156 (IGF1R)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100172156 (IGF1R)
Protein kinases [BR:
pon01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100172156 (IGF1R)
CD molecules [BR:
pon04090
]
Proteins
100172156 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Recep_L_domain
fn3
Furin-like
Kinase-like
Insulin_TMD
DUF4476
Motif
Other DBs
NCBI-GeneID:
100172156
NCBI-ProteinID:
NP_001125259
Ensembl:
ENSPPYG00000006808
UniProt:
Q5RCL1
LinkDB
All DBs
Position
15
AA seq
1064 aa
AA seq
DB search
MQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLIN
IRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVL
DNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNG
ERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDA
CGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILY
IRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYC
SKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFE
NFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVD
NKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFVRTMPAEGADDIPGPVTWEPR
PENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTA
RIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRN
NSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVK
DEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT
RGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV
AEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLW
EIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRLAFLEII
SSIKDEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGH
KAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
3195 nt
NT seq
+upstream
nt +downstream
nt
atgcaggagtgcccctcgggcttcatccgcaacggcagccagagcatgtactgcatccca
tgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaagaccattgattct
gttacttctgctcagatgctccaaggatgcaccatcttcaagggcaatttgctcattaac
atccgacgggggaataacattgcttcagaactggagaacttcatggggctcatcgaggtg
gtgacgggctacgtgaagatccgccattctcatgccttggtctccttgtccttcctaaaa
aaccttcgcctcatcttaggagaggagcagctagaagggaattactccttctacgtcctc
gacaaccagaacttgcagcaactatgggactgggaccaccgcaacctgaccatcaaagca
gggaaaatgtactttgctttcaatcccaaattatgtgtttctgaaatttaccgcatggag
gaagtgacggggactaaaggacgccaaagcaaaggggacataaacaccaggaacaacggg
gagagagcctcctgtgaaagtgatgtcctgcatttcacctccaccaccacgtcgaagaat
cgcatcatcataacctggcaccggtaccggccccctgactacagggatctcatcagcttc
accgtttactacaaggaagcaccctttaagaatgtcacggagtatgatgggcaggacgcc
tgcggctccaacagctggaacatggtggacgtggacctcccacccaacaaggacgtggag
cccggcatcttactgcatgggctgaagccctggactcagtacgccgtttacgtcaaggct
gtgaccctcaccatggtggagaacgaccatatccgtggagccaagagtgagatcttgtac
attcgcaccaatgcttcagttccttccattcccttggacgttctttcagcatcgaactcc
tcttctcagttaatcgtgaagtggaaccctccctctctgcccaacggcaacctgagttac
tacattgtgcgctggcagcggcagcctcaggacggctacctttaccggcacaattactgc
tccaaagacaaaatccccatcaggaagtatgccgacggcaccatcgacattgaggaagtc
acagagaaccccaagactgaggtgtgtggtggtgagaaagggccttgctgcgcctgcccc
aaaactgaagccgagaagcaggctgagaaggaggaggctgagtaccgcaaagtctttgag
aatttcctgcacaactccatcttcgtgcccagacctgaaaggaagcggagagatgtcatg
caagtggccaacaccaccatgtccagccgaagcaggaacaccacggccgcagacacgtac
aacatcaccgacccagaagagctggagacagagtaccctttctttgagagcagagtggat
aacaaggagagaactgtcatttctaaccttcggcctttcacattgtaccgcatcgatatc
cacagctgcaatcatgaggctgagaagctgggctgcagcgcctccaacttcgtctttgta
aggactatgcccgcagaaggagcagatgacattcctgggccagtgacctgggagccaagg
cctgaaaactccatctttttaaagtggccagaacctgagaatcccaatggattgattcta
atgtatgaaataaaatacggatcacaagttgaggatcagcgagaatgtgtgtccagacag
gaatacaggaagtatggaggggccaagctaaaccggctaaacccggggaactacacagcc
cggattcaggccacatctctctctgggaatgggtcgtggacagatcctgtgttcttctat
gtccaggccaaaacaggatatgaaaacttcatccatctgatcatcgctctgcccgtcgct
gtcctgttgattgtgggagggttggtgattatgctgtacgtcttccatagaaagagaaat
aacagcaggctggggaatggagtgctgtatgcctctgtgaacccggagtacttcagcgct
gcggatgtgtacgttcctgatgagtgggaggtggctcgggagaagatcaccatgagccgg
gaacttgggcaggggtcgtttgggatggtctatgaaggagttgccaagggtgtggtgaaa
gatgaacctgaaaccagagtggccattaaaacagtgaacgaggccgcaagcatgcgtgaa
aggatcgagtttctcaacgaagcttctgtgatgaaggagttcaattgtcaccatgtggtg
cgattgctgggtgtggtgtcccaaggccagccaacactggtcatcatggaactgatgaca
cggggcgatctcaaaagttatctccggtctctgaggccagaaatggagaataatccagtc
ctagcacctccaagcctaagcaagatgattcagatggccggagagattgcagacggcatg
gcatacctcaacgccaacaagttcgtccacagagaccttgctgcccggaattgcatggta
gccgaagatttcacagtcaaaatcggagattttggtatgacgcgagatatctatgagaca
gactattaccggaaaggagggaaagggctgctgcccgtgcgctggatgtctcccgagtcc
ctcaaggatggagtcttcaccacttactcggacgtctggtccttcggggtcgtcctctgg
gagattgccacactggccgagcagccctaccagggcttgtccaacgagcaagtccttcgc
ttcgtcatggagggcggccttctggacaagccagacaactgtcctgacatgctgtttgaa
ctgatgcgcatgtgctggcagtataaccccaagatgaggcttgccttcctggagatcatc
agcagcatcaaagacgagatggagcctggcttccgggaggtctccttctactacagcgag
gagaacaagctgcccgagccggaggaactggacctcgagccagagaacatggagagcgtc
cccctggacccctcggcctcctcgtcctccctgccactgcccgacagacactcaggacac
aaggccgagaacggccccggccctggagtactggtcctccgcgccagcttcgacgagaga
cagccttacgcacacatgaacgggggccgcaagaacgagcgggccttgccactgccccag
tcttcgacctgctga
DBGET
integrated database retrieval system
