Pongo abelii (Sumatran orangutan): 100173994
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Entry
100173994 CDS
T01416
Symbol
HIF1A
Name
(RefSeq) hypoxia-inducible factor 1-alpha
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04066
HIF-1 signaling pathway
pon04137
Mitophagy - animal
pon04140
Autophagy - animal
pon04148
Efferocytosis
pon04659
Th17 cell differentiation
pon04919
Thyroid hormone signaling pathway
pon05167
Kaposi sarcoma-associated herpesvirus infection
pon05200
Pathways in cancer
pon05205
Proteoglycans in cancer
pon05208
Chemical carcinogenesis - reactive oxygen species
pon05211
Renal cell carcinoma
pon05230
Central carbon metabolism in cancer
pon05231
Choline metabolism in cancer
pon05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100173994 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100173994 (HIF1A)
04137 Mitophagy - animal
100173994 (HIF1A)
04148 Efferocytosis
100173994 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
100173994 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100173994 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100173994 (HIF1A)
05205 Proteoglycans in cancer
100173994 (HIF1A)
05208 Chemical carcinogenesis - reactive oxygen species
100173994 (HIF1A)
05230 Central carbon metabolism in cancer
100173994 (HIF1A)
05231 Choline metabolism in cancer
100173994 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100173994 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
100173994 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
100173994 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
pon03000
]
100173994 (HIF1A)
Transcription factors [BR:
pon03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
100173994 (HIF1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
DDRGK
Motif
Other DBs
NCBI-GeneID:
100173994
NCBI-ProteinID:
NP_001126975
Ensembl:
ENSPPYG00000005881
UniProt:
Q5R4G1
LinkDB
All DBs
Position
15:65807313..65858868
Genome browser
AA seq
827 aa
AA seq
DB search
MEGAGGANDKKNRISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASV
MRLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKY
MGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVKKGKEQNTQRSFFLRMKCTLTSRG
RTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDS
KTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQ
VTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTEC
VLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTE
TDDQQLEEVPLYNDVMLPSPNEKLQNINLAMSPLPTAETPKPLRSSADPALNQEVALKLE
PNPESLELSFTMPQIQDQPPSPSDGSTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKL
FAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPESASPQSTV
TVFQQTQIQEPTANATTTTATTDELKTVTKDRMEDIKILIASPSPTHIHKETTSATSSPY
RDTQSRTASPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTVPEEELNPKILALQNAQRK
RKMEHDGSLFQAVGIGTLLQQPEDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLA
CRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2484 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgcgaacgacaagaaaaataggataagttctgaacgtcgaaaa
gaaaagtctcgagatgcagccagatctcggcgaagtaaagaatctgaagttttttatgag
cttgctcatcagttgccacttccacataatgtgagttcgcatcttgataaggcctctgtg
atgaggcttaccatcagctatttgcgtgtgaggaaacttctggatgctggtgatttggat
attgaagatgaaatgaaagcacagatgaattgcttttatttgaaagccttggatggtttt
gttatggttctcacagatgatggtgacatgatttacatttctgataatgtgaacaaatac
atgggattaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgt
gaccatgaggaaatgagagaaatgcttacacacagaaatggccctgtgaaaaagggtaaa
gaacagaacacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgagga
agaactatgaacataaagtctgcaacatggaaggtattgcactgcacaggccatattcac
gtatatgataccaacagtaaccaacctcagtgtgggtataagaaaccacctatgacctgc
ttggtgctgatttgtgaacccattcctcacccatcaaatattgaaattcctttagatagc
aagactttcctcagtcgacacagcctggatatgaaattttcttattgtgatgaaagaatt
accgaattgatgggatatgagccagaagaacttttaggccgctcaatttatgaatattat
catgctttggactctgatcatctgaccaaaactcatcatgacatgtttactaaaggacaa
gttaccacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaact
caagcaactgtcatatataacaccaagaattctcaaccacagtgcattgtatgtgtgaat
tatgttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgt
gtccttaaaccggttgaatcttcagatatgaaaatgactcagctattcaccaaagttgaa
tcagaagacacaagtagcctctttgacaaacttaagaaggaacctgatgctttaactttg
ctggccccagccgctggagacacaatcatatctttagattttggcagcaatgacacagaa
actgatgaccagcaacttgaggaagtaccattatataatgatgtaatgctcccctcaccc
aacgaaaaattacagaatataaatttggcaatgtctccattacccaccgctgaaacacca
aagccacttcgaagtagtgctgaccctgcactcaatcaagaagttgcattaaaattagaa
ccaaatccagagtcactggaactttcttttaccatgccccagattcaggatcagccacct
agtccttctgatggaagcactagacaaagttcacctgagcctaatagtcccagtgaatat
tgtttttatgtggatagtgatatggtcaatgaattcaagttggaattggtagaaaaactt
tttgctgaagacacagaagcaaagaacccattttctactcaggacacagatttagacttg
gagatgttagctccctatatcccaatggatgatgacttccagttacgttccttcgatcag
ttgtcaccattagaaagcagttccgcaagccctgaaagcgcaagtcctcaaagcacagtt
acagtattccagcagactcaaatacaagaacctactgctaatgccaccactaccactgcc
accactgatgaattaaaaacagtgacaaaagaccgtatggaagacattaaaatactgatt
gcatctccatctcctacccacatacataaagaaactactagtgccacatcatcaccatat
agagatactcaaagtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacag
acagaaaaatctcatccaagaagccctaacgtgttatctgtcgctttgagtcaaagaact
acagttcctgaggaagaactaaatccaaagatactagctttgcagaatgctcagagaaag
cgaaaaatggaacatgatggttcactttttcaagcagtaggaattggaacattattacag
cagccagaggatcatgcagctactacatcactttcttggaaacgtgtaaaaggatgcaaa
tctagtgaacagaatggaatggagcaaaagacaattattttaataccttctgatttagca
tgtagactgctggggcaatcaatggatgaaagtggattaccacagctgaccagttatgat
tgtgaagttaatgctcctatacaaggcagcagaaacctactgcagggtgaagaattactc
agagctttggatcaagttaactga
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