Pongo abelii (Sumatran orangutan): 100173994
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Entry
100173994 CDS
T01416
Gene name
HIF1A
Definition
(RefSeq) hypoxia-inducible factor 1-alpha
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04066
HIF-1 signaling pathway
pon04137
Mitophagy - animal
pon04140
Autophagy - animal
pon04659
Th17 cell differentiation
pon04919
Thyroid hormone signaling pathway
pon05167
Kaposi sarcoma-associated herpesvirus infection
pon05200
Pathways in cancer
pon05205
Proteoglycans in cancer
pon05211
Renal cell carcinoma
pon05230
Central carbon metabolism in cancer
pon05231
Choline metabolism in cancer
pon05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100173994 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100173994 (HIF1A)
04137 Mitophagy - animal
100173994 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
100173994 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100173994 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100173994 (HIF1A)
05205 Proteoglycans in cancer
100173994 (HIF1A)
05230 Central carbon metabolism in cancer
100173994 (HIF1A)
05231 Choline metabolism in cancer
100173994 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100173994 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
100173994 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
100173994 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
pon03000
]
100173994 (HIF1A)
Transcription factors [BR:
pon03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
100173994 (HIF1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PAS_3
HIF-1a_CTAD
PAS_11
HIF-1
PAS
PAS_9
PAS_4
DDRGK
HLH
Motif
Other DBs
NCBI-GeneID:
100173994
NCBI-ProteinID:
NP_001126975
UniProt:
Q5R4G1
LinkDB
All DBs
Position
14
AA seq
827 aa
AA seq
DB search
MEGAGGANDKKNRISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASV
MRLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKY
MGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVKKGKEQNTQRSFFLRMKCTLTSRG
RTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDS
KTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQ
VTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTEC
VLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTE
TDDQQLEEVPLYNDVMLPSPNEKLQNINLAMSPLPTAETPKPLRSSADPALNQEVALKLE
PNPESLELSFTMPQIQDQPPSPSDGSTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKL
FAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPESASPQSTV
TVFQQTQIQEPTANATTTTATTDELKTVTKDRMEDIKILIASPSPTHIHKETTSATSSPY
RDTQSRTASPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTVPEEELNPKILALQNAQRK
RKMEHDGSLFQAVGIGTLLQQPEDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLA
CRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2484 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgcgaacgacaagaaaaataggataagttctgaacgtcgaaaa
gaaaagtctcgagatgcagccagatctcggcgaagtaaagaatctgaagttttttatgag
cttgctcatcagttgccacttccacataatgtgagttcgcatcttgataaggcctctgtg
atgaggcttaccatcagctatttgcgtgtgaggaaacttctggatgctggtgatttggat
attgaagatgaaatgaaagcacagatgaattgcttttatttgaaagccttggatggtttt
gttatggttctcacagatgatggtgacatgatttacatttctgataatgtgaacaaatac
atgggattaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgt
gaccatgaggaaatgagagaaatgcttacacacagaaatggccctgtgaaaaagggtaaa
gaacagaacacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgagga
agaactatgaacataaagtctgcaacatggaaggtattgcactgcacaggccatattcac
gtatatgataccaacagtaaccaacctcagtgtgggtataagaaaccacctatgacctgc
ttggtgctgatttgtgaacccattcctcacccatcaaatattgaaattcctttagatagc
aagactttcctcagtcgacacagcctggatatgaaattttcttattgtgatgaaagaatt
accgaattgatgggatatgagccagaagaacttttaggccgctcaatttatgaatattat
catgctttggactctgatcatctgaccaaaactcatcatgacatgtttactaaaggacaa
gttaccacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaact
caagcaactgtcatatataacaccaagaattctcaaccacagtgcattgtatgtgtgaat
tatgttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgt
gtccttaaaccggttgaatcttcagatatgaaaatgactcagctattcaccaaagttgaa
tcagaagacacaagtagcctctttgacaaacttaagaaggaacctgatgctttaactttg
ctggccccagccgctggagacacaatcatatctttagattttggcagcaatgacacagaa
actgatgaccagcaacttgaggaagtaccattatataatgatgtaatgctcccctcaccc
aacgaaaaattacagaatataaatttggcaatgtctccattacccaccgctgaaacacca
aagccacttcgaagtagtgctgaccctgcactcaatcaagaagttgcattaaaattagaa
ccaaatccagagtcactggaactttcttttaccatgccccagattcaggatcagccacct
agtccttctgatggaagcactagacaaagttcacctgagcctaatagtcccagtgaatat
tgtttttatgtggatagtgatatggtcaatgaattcaagttggaattggtagaaaaactt
tttgctgaagacacagaagcaaagaacccattttctactcaggacacagatttagacttg
gagatgttagctccctatatcccaatggatgatgacttccagttacgttccttcgatcag
ttgtcaccattagaaagcagttccgcaagccctgaaagcgcaagtcctcaaagcacagtt
acagtattccagcagactcaaatacaagaacctactgctaatgccaccactaccactgcc
accactgatgaattaaaaacagtgacaaaagaccgtatggaagacattaaaatactgatt
gcatctccatctcctacccacatacataaagaaactactagtgccacatcatcaccatat
agagatactcaaagtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacag
acagaaaaatctcatccaagaagccctaacgtgttatctgtcgctttgagtcaaagaact
acagttcctgaggaagaactaaatccaaagatactagctttgcagaatgctcagagaaag
cgaaaaatggaacatgatggttcactttttcaagcagtaggaattggaacattattacag
cagccagaggatcatgcagctactacatcactttcttggaaacgtgtaaaaggatgcaaa
tctagtgaacagaatggaatggagcaaaagacaattattttaataccttctgatttagca
tgtagactgctggggcaatcaatggatgaaagtggattaccacagctgaccagttatgat
tgtgaagttaatgctcctatacaaggcagcagaaacctactgcagggtgaagaattactc
agagctttggatcaagttaactga
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