Pongo abelii (Sumatran orangutan): 100438875
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Entry
100438875 CDS
T01416
Gene name
SYK
Definition
(RefSeq) tyrosine-protein kinase SYK isoform X1
KO
K05855
spleen tyrosine kinase [EC:
2.7.10.2
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04064
NF-kappa B signaling pathway
pon04072
Phospholipase D signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04380
Osteoclast differentiation
pon04611
Platelet activation
pon04613
Neutrophil extracellular trap formation
pon04625
C-type lectin receptor signaling pathway
pon04650
Natural killer cell mediated cytotoxicity
pon04662
B cell receptor signaling pathway
pon04664
Fc epsilon RI signaling pathway
pon04666
Fc gamma R-mediated phagocytosis
pon05152
Tuberculosis
pon05167
Kaposi sarcoma-associated herpesvirus infection
pon05168
Herpes simplex virus 1 infection
pon05169
Epstein-Barr virus infection
pon05171
Coronavirus disease - COVID-19
pon05203
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
100438875 (SYK)
04072 Phospholipase D signaling pathway
100438875 (SYK)
04151 PI3K-Akt signaling pathway
100438875 (SYK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100438875 (SYK)
04613 Neutrophil extracellular trap formation
100438875 (SYK)
04625 C-type lectin receptor signaling pathway
100438875 (SYK)
04650 Natural killer cell mediated cytotoxicity
100438875 (SYK)
04662 B cell receptor signaling pathway
100438875 (SYK)
04664 Fc epsilon RI signaling pathway
100438875 (SYK)
04666 Fc gamma R-mediated phagocytosis
100438875 (SYK)
09158 Development and regeneration
04380 Osteoclast differentiation
100438875 (SYK)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
100438875 (SYK)
09171 Infectious disease: bacterial
05152 Tuberculosis
100438875 (SYK)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
100438875 (SYK)
05168 Herpes simplex virus 1 infection
100438875 (SYK)
05167 Kaposi sarcoma-associated herpesvirus infection
100438875 (SYK)
05169 Epstein-Barr virus infection
100438875 (SYK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100438875 (SYK)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100438875 (SYK)
Protein kinases [BR:
pon01001
]
Non-receptor tyrosine kinases
SYK family
100438875 (SYK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
Kdo
Motif
Other DBs
NCBI-GeneID:
100438875
NCBI-ProteinID:
XP_024108425
LinkDB
All DBs
Position
9
AA seq
635 aa
AA seq
DB search
MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
PGHRKPSPAQGNRQESTVSFNPYEPELASWAAEKGPQREALPMDTEVYESPYADPEEIRP
KEVYLDRNLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKNELLAE
ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
NT seq
1908 nt
NT seq
+upstream
nt +downstream
nt
atggccagcagcggcatggctgacagcgccaaccacctgcccttctttttcggcaatatc
acccgggaggaggcagaagattacctggtccaggggggcatgagtgatgggctctatttg
ctgcgccagagccgcaactacctgggcggcttcgccctgtccgtggcccacgggaggaag
gcacaccactacaccatcgagcgggagctgaacggcacctacgccatcgccggcggcagg
acccatgccagccccgccgacctctgccactaccactcccaggagtctgatggcctggtc
tgcctcctcaagaagcccttcaaccggccccaaggggtgcagcccaagactgggcccttt
gaggacttgaaggaaaacctcatcagggaatatgtgaagcagacatggaacctgcagggt
caggctctggaacaggccatcatcagtcagaagcctcagctggagaagctgatcgccacc
acagcccatgaaaaaatgccttggttccatggaaaaatctctcgggaagaatctgagcaa
attgtcctgataggatcaaagacaaatggaaagttcctgatccgagccagagacaacaac
ggttcctacgccctgtgcctgctgcacgaagggaaggtgctgcactatcgcatcgacaaa
gacaagacagggaagctctccatccccgagggaaagaagttcgacacgctctggcagctg
gtcgagcattattcttataaagcagatggtttgttaagagttcttactgtcccatgtcaa
aaaatcggcacacagggaaatgttaattttggaggccgtccacaacttccaggttcccat
cctgcgacttggtcagcgggtggaataatctcaagaatcaaatcatactccttcccaaag
cctggccacagaaagccctcccctgcccaagggaaccggcaagagagtactgtgtcgttc
aatccgtatgagccagaacttgcatcctgggctgcagaaaaaggcccccagagagaagcc
ctacccatggacacagaggtgtacgagagcccctacgcagaccccgaggagatcaggccc
aaggaggtttatctggaccgaaatctgctgacgctggaagacaaagaactgggctctggt
aattttggaactgtgaaaaagggctactaccaaatgaaaaaagttgtgaaaaccgtggct
gtgaaaatactgaaaaacgaggccaatgaccccgctcttaaaaatgagttattagcagaa
gcaaatgtcatgcagcagctggacaacccgtacatcgtgcgcatgatcgggatatgcgag
gccgagtcctggatgctggttatggagatggcagaacttggtcccctcaataagtatttg
cagcagaacagacatgtcaaggataaaaacatcatagaactggttcatcaggtttccatg
ggcatgaaatatttggaggagagcaattttgtgcacagagatctggctgcaagaaatgtg
ttgctagttactcaacattacgccaagatcagtgattttggactttccaaagcactgcgt
gctgatgaaaactactacaaggcccagacccatggaaagtggcctgtcaagtggtacgct
ccagaatgcatcaactactacaagttctccagcaaaagcgatgtctggagctttggagtg
ttgatgtgggaagcattctcctatgggcagaagccgtatcgagggatgaaaggaagtgaa
gtcactgctatgttagagaaaggagagcggatggggtgccctgcagggtgtccaagagag
atgtacgatctcatgaatctgtgctggacatatgatgtggaaaacaggcccggattcgca
gcagtggaactgcggctgcgcaattactactatgacgtggtgaactaa
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