KEGG   Pongo abelii (Sumatran orangutan): 100439900
Entry
100439900         CDS       T01416                                 

Gene name
PRKCB
Definition
(RefSeq) protein kinase C beta type isoform X2
  KO
K19662  classical protein kinase C beta type [EC:2.7.11.13]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon04010  MAPK signaling pathway
pon04012  ErbB signaling pathway
pon04014  Ras signaling pathway
pon04015  Rap1 signaling pathway
pon04020  Calcium signaling pathway
pon04062  Chemokine signaling pathway
pon04064  NF-kappa B signaling pathway
pon04066  HIF-1 signaling pathway
pon04070  Phosphatidylinositol signaling system
pon04071  Sphingolipid signaling pathway
pon04150  mTOR signaling pathway
pon04270  Vascular smooth muscle contraction
pon04310  Wnt signaling pathway
pon04370  VEGF signaling pathway
pon04510  Focal adhesion
pon04540  Gap junction
pon04613  Neutrophil extracellular trap formation
pon04650  Natural killer cell mediated cytotoxicity
pon04662  B cell receptor signaling pathway
pon04666  Fc gamma R-mediated phagocytosis
pon04670  Leukocyte transendothelial migration
pon04713  Circadian entrainment
pon04720  Long-term potentiation
pon04723  Retrograde endocannabinoid signaling
pon04724  Glutamatergic synapse
pon04725  Cholinergic synapse
pon04726  Serotonergic synapse
pon04727  GABAergic synapse
pon04728  Dopaminergic synapse
pon04730  Long-term depression
pon04750  Inflammatory mediator regulation of TRP channels
pon04911  Insulin secretion
pon04912  GnRH signaling pathway
pon04916  Melanogenesis
pon04918  Thyroid hormone synthesis
pon04919  Thyroid hormone signaling pathway
pon04921  Oxytocin signaling pathway
pon04925  Aldosterone synthesis and secretion
pon04928  Parathyroid hormone synthesis, secretion and action
pon04929  GnRH secretion
pon04931  Insulin resistance
pon04933  AGE-RAGE signaling pathway in diabetic complications
pon04935  Growth hormone synthesis, secretion and action
pon04960  Aldosterone-regulated sodium reabsorption
pon04961  Endocrine and other factor-regulated calcium reabsorption
pon04970  Salivary secretion
pon04971  Gastric acid secretion
pon04972  Pancreatic secretion
pon04973  Carbohydrate digestion and absorption
pon05017  Spinocerebellar ataxia
pon05022  Pathways of neurodegeneration - multiple diseases
pon05031  Amphetamine addiction
pon05032  Morphine addiction
pon05140  Leishmaniasis
pon05143  African trypanosomiasis
pon05146  Amoebiasis
pon05161  Hepatitis B
pon05163  Human cytomegalovirus infection
pon05164  Influenza A
pon05170  Human immunodeficiency virus 1 infection
pon05171  Coronavirus disease - COVID-19
pon05200  Pathways in cancer
pon05205  Proteoglycans in cancer
pon05206  MicroRNAs in cancer
pon05214  Glioma
pon05223  Non-small cell lung cancer
pon05225  Hepatocellular carcinoma
pon05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100439900 (PRKCB)
   04012 ErbB signaling pathway
    100439900 (PRKCB)
   04014 Ras signaling pathway
    100439900 (PRKCB)
   04015 Rap1 signaling pathway
    100439900 (PRKCB)
   04310 Wnt signaling pathway
    100439900 (PRKCB)
   04370 VEGF signaling pathway
    100439900 (PRKCB)
   04064 NF-kappa B signaling pathway
    100439900 (PRKCB)
   04066 HIF-1 signaling pathway
    100439900 (PRKCB)
   04020 Calcium signaling pathway
    100439900 (PRKCB)
   04070 Phosphatidylinositol signaling system
    100439900 (PRKCB)
   04071 Sphingolipid signaling pathway
    100439900 (PRKCB)
   04150 mTOR signaling pathway
    100439900 (PRKCB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100439900 (PRKCB)
   04540 Gap junction
    100439900 (PRKCB)
 09150 Organismal Systems
  09151 Immune system
   04613  Neutrophil extracellular trap formation
    100439900 (PRKCB)
   04650 Natural killer cell mediated cytotoxicity
    100439900 (PRKCB)
   04662 B cell receptor signaling pathway
    100439900 (PRKCB)
   04666 Fc gamma R-mediated phagocytosis
    100439900 (PRKCB)
   04670 Leukocyte transendothelial migration
    100439900 (PRKCB)
   04062 Chemokine signaling pathway
    100439900 (PRKCB)
  09152 Endocrine system
   04911 Insulin secretion
    100439900 (PRKCB)
   04929 GnRH secretion
    100439900 (PRKCB)
   04912 GnRH signaling pathway
    100439900 (PRKCB)
   04921 Oxytocin signaling pathway
    100439900 (PRKCB)
   04935 Growth hormone synthesis, secretion and action
    100439900 (PRKCB)
   04918 Thyroid hormone synthesis
    100439900 (PRKCB)
   04919 Thyroid hormone signaling pathway
    100439900 (PRKCB)
   04928 Parathyroid hormone synthesis, secretion and action
    100439900 (PRKCB)
   04916 Melanogenesis
    100439900 (PRKCB)
   04925 Aldosterone synthesis and secretion
    100439900 (PRKCB)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    100439900 (PRKCB)
  09154 Digestive system
   04970 Salivary secretion
    100439900 (PRKCB)
   04971 Gastric acid secretion
    100439900 (PRKCB)
   04972 Pancreatic secretion
    100439900 (PRKCB)
   04973 Carbohydrate digestion and absorption
    100439900 (PRKCB)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100439900 (PRKCB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100439900 (PRKCB)
  09156 Nervous system
   04724 Glutamatergic synapse
    100439900 (PRKCB)
   04727 GABAergic synapse
    100439900 (PRKCB)
   04725 Cholinergic synapse
    100439900 (PRKCB)
   04728 Dopaminergic synapse
    100439900 (PRKCB)
   04726 Serotonergic synapse
    100439900 (PRKCB)
   04720 Long-term potentiation
    100439900 (PRKCB)
   04730 Long-term depression
    100439900 (PRKCB)
   04723 Retrograde endocannabinoid signaling
    100439900 (PRKCB)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100439900 (PRKCB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100439900 (PRKCB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100439900 (PRKCB)
   05206 MicroRNAs in cancer
    100439900 (PRKCB)
   05205 Proteoglycans in cancer
    100439900 (PRKCB)
   05231 Choline metabolism in cancer
    100439900 (PRKCB)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100439900 (PRKCB)
   05214 Glioma
    100439900 (PRKCB)
   05223 Non-small cell lung cancer
    100439900 (PRKCB)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    100439900 (PRKCB)
   05022 Pathways of neurodegeneration - multiple diseases
    100439900 (PRKCB)
  09165 Substance dependence
   05031 Amphetamine addiction
    100439900 (PRKCB)
   05032 Morphine addiction
    100439900 (PRKCB)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100439900 (PRKCB)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100439900 (PRKCB)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100439900 (PRKCB)
   05161 Hepatitis B
    100439900 (PRKCB)
   05171 Coronavirus disease - COVID-19
    100439900 (PRKCB)
   05164 Influenza A
    100439900 (PRKCB)
   05163 Human cytomegalovirus infection
    100439900 (PRKCB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100439900 (PRKCB)
   05140 Leishmaniasis
    100439900 (PRKCB)
   05143 African trypanosomiasis
    100439900 (PRKCB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100439900 (PRKCB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pon01001]
    100439900 (PRKCB)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     100439900 (PRKCB)
Protein kinases [BR:pon01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   100439900 (PRKCB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 Kinase-like CEP76-C2 APH
Other DBs
NCBI-GeneID: 100439900
NCBI-ProteinID: XP_002826292
LinkDB
Position
16
AA seq 671 aa
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS
LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL
SVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEE
LRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM
EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI
KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF
RYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGF
SYTNPEFVINV
NT seq 2016 nt   +upstreamnt  +downstreamnt
atggctgacccggctgcggggccgccgccgagcgagggcgaggagagcaccgtgcgcttc
gcccgcaaaggcgccctccggcagaagaacgtgcatgaggtcaagaaccacaaattcacc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttc
gggaaacagggattccagtgccaagtttgctgctttgtggtgcacaagcggtgccatgaa
tttgtcacattctcctgccctggcgctgacaagggtccagcctctgatgacccccggagc
aaacacaagtttaagatccacacgtactccagccccacgttttgtgaccactgtgggtca
ctgctgtatggactcatccaccaggggatgaaatgtgacacctgcatgatgaatgtgcac
aagcgctgcgtgatgaacgttcccagcctgtgtggcacggaccacacggagcgccgcggc
cgcatctacatccaggcccacatcgacagggacgtcctcattgtcctcgtaagagatgct
aaaaaccttgtacctatggaccccaatggcctgtcagatccctacgtaaaactgaaactg
attcccgatcccaaaagtgagagcaaacagaagaccaaaaccatcaaatgctccctcaac
cccgagtggaacgagacatttagatttcagctgaaagaatcggacaaagacagaagactg
tcagtagagatctgggattgggatttgaccagcaggaatgacttcatgggatctttgtcc
tttgggatttctgaactgcaaaaagccagtgttgatggctggtttaagttactgagccag
gaggaaggcgagtacttcaatgtgcctgtgccaccagaaggaagtgaggccaatgaagaa
ctgcggcagaaatttgagagggccaagatcagtcaggggaccaaggtcccagaagaaaag
acgaccaacactgtctccaaatttgacaacaatggcaacagagaccggatgaaactgacc
gattttaacttcctaatggtgctggggaaaggcagctttggcaaggtcatgctttcagaa
cgaaaaggcacagatgagctctatgctgtgaagatcctgaagaaggacgttgtgatccaa
gatgatgacgtggagtgcactatggtggagaagcgggtgctggccctgcccgggaagcca
cccttcctgacccagctccactcctgcttccagaccatggaccgcctgtactttgtgatg
gagtacgtgaatgggggcgacctcatgtatcacatccagcaagtcggccggttcaaggag
ccccatgctgtattttacgctgcagaaattgccatcggtctgttcttcttacagagtaag
ggcatcatttaccgtgacctaaaacttgacaacgtgatgctcgattctgaggggcacatc
aagattgctgattttggcatgtgtaaggaaaacatctgggatggggtgacaaccaagaca
ttctgtggcactccagactacatcgcccccgagataattgcttatcagccctatgggaag
tccgtggattggtgggcatttggagtcctgctgtatgaaatgttggctgggcaggcaccc
tttgaaggggaggatgaagatgaactcttccaatccatcatggaacacaacgtagcctat
cccaagtctatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacaccca
ggcaaacgtctgggttgtggacctgaaggcgaacgtgatatcaaagagcatgcatttttc
cggtatattgattgggagaaacttgaacgcaaagagatccagcccccatataagccaaaa
gctagagacaagagagacacctccaacttcgacaaagagttcaccagacagcctgtggaa
ctgacccccactgataaactcttcatcatgaacttggaccaaaatgaatttgctggcttc
tcttatactaacccagagtttgtcattaatgtgtag

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