Pongo abelii (Sumatran orangutan): 100447772
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Entry
100447772 CDS
T01416
Gene name
GSK3B
Definition
(RefSeq) glycogen synthase kinase-3 beta isoform X1
KO
K03083
glycogen synthase kinase 3 beta [EC:
2.7.11.26
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon04012
ErbB signaling pathway
pon04062
Chemokine signaling pathway
pon04110
Cell cycle
pon04150
mTOR signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04310
Wnt signaling pathway
pon04340
Hedgehog signaling pathway
pon04360
Axon guidance
pon04390
Hippo signaling pathway
pon04510
Focal adhesion
pon04550
Signaling pathways regulating pluripotency of stem cells
pon04657
IL-17 signaling pathway
pon04660
T cell receptor signaling pathway
pon04662
B cell receptor signaling pathway
pon04722
Neurotrophin signaling pathway
pon04728
Dopaminergic synapse
pon04910
Insulin signaling pathway
pon04916
Melanogenesis
pon04917
Prolactin signaling pathway
pon04919
Thyroid hormone signaling pathway
pon04931
Insulin resistance
pon04932
Non-alcoholic fatty liver disease
pon04934
Cushing syndrome
pon04935
Growth hormone synthesis, secretion and action
pon05010
Alzheimer disease
pon05020
Prion disease
pon05022
Pathways of neurodegeneration - multiple diseases
pon05135
Yersinia infection
pon05160
Hepatitis C
pon05162
Measles
pon05163
Human cytomegalovirus infection
pon05165
Human papillomavirus infection
pon05167
Kaposi sarcoma-associated herpesvirus infection
pon05200
Pathways in cancer
pon05210
Colorectal cancer
pon05213
Endometrial cancer
pon05215
Prostate cancer
pon05217
Basal cell carcinoma
pon05224
Breast cancer
pon05225
Hepatocellular carcinoma
pon05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100447772 (GSK3B)
04310 Wnt signaling pathway
100447772 (GSK3B)
04340 Hedgehog signaling pathway
100447772 (GSK3B)
04390 Hippo signaling pathway
100447772 (GSK3B)
04151 PI3K-Akt signaling pathway
100447772 (GSK3B)
04150 mTOR signaling pathway
100447772 (GSK3B)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100447772 (GSK3B)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100447772 (GSK3B)
04550 Signaling pathways regulating pluripotency of stem cells
100447772 (GSK3B)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
100447772 (GSK3B)
04657 IL-17 signaling pathway
100447772 (GSK3B)
04662 B cell receptor signaling pathway
100447772 (GSK3B)
04062 Chemokine signaling pathway
100447772 (GSK3B)
09152 Endocrine system
04910 Insulin signaling pathway
100447772 (GSK3B)
04917 Prolactin signaling pathway
100447772 (GSK3B)
04935 Growth hormone synthesis, secretion and action
100447772 (GSK3B)
04919 Thyroid hormone signaling pathway
100447772 (GSK3B)
04916 Melanogenesis
100447772 (GSK3B)
09156 Nervous system
04728 Dopaminergic synapse
100447772 (GSK3B)
04722 Neurotrophin signaling pathway
100447772 (GSK3B)
09158 Development and regeneration
04360 Axon guidance
100447772 (GSK3B)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100447772 (GSK3B)
09162 Cancer: specific types
05210 Colorectal cancer
100447772 (GSK3B)
05225 Hepatocellular carcinoma
100447772 (GSK3B)
05226 Gastric cancer
100447772 (GSK3B)
05217 Basal cell carcinoma
100447772 (GSK3B)
05215 Prostate cancer
100447772 (GSK3B)
05213 Endometrial cancer
100447772 (GSK3B)
05224 Breast cancer
100447772 (GSK3B)
09164 Neurodegenerative disease
05010 Alzheimer disease
100447772 (GSK3B)
05020 Prion disease
100447772 (GSK3B)
05022 Pathways of neurodegeneration - multiple diseases
100447772 (GSK3B)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100447772 (GSK3B)
04931 Insulin resistance
100447772 (GSK3B)
04934 Cushing syndrome
100447772 (GSK3B)
09171 Infectious disease: bacterial
05135 Yersinia infection
100447772 (GSK3B)
09172 Infectious disease: viral
05160 Hepatitis C
100447772 (GSK3B)
05162 Measles
100447772 (GSK3B)
05163 Human cytomegalovirus infection
100447772 (GSK3B)
05167 Kaposi sarcoma-associated herpesvirus infection
100447772 (GSK3B)
05165 Human papillomavirus infection
100447772 (GSK3B)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100447772 (GSK3B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100447772 (GSK3B)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pon03036
]
100447772 (GSK3B)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.26 tau-protein kinase
100447772 (GSK3B)
Protein kinases [BR:
pon01001
]
Serine/threonine kinases: CMGC group
GSK family [OT]
100447772 (GSK3B)
Chromosome and associated proteins [BR:
pon03036
]
Eukaryotic type
Centrosome formation and ciliogenesis proteins
Kinases and associated factors
100447772 (GSK3B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
APH
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
100447772
NCBI-ProteinID:
XP_024100347
Ensembl:
ENSPPYG00000013507
LinkDB
All DBs
Position
3
AA seq
433 aa
AA seq
DB search
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN
VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQ
TNNAASASASNST
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccggtgcagcagcct
tcagcttttggcagcatgaaagttagcagagacaaggacggcagcaaggtgacaacagtg
gtggcaactcctgggcagggtccagacaggccacaagaagtcagctacacagacactaaa
gtgattggaaatggatcatttggtgtggtatatcaagccaaactttgtgattcgggagaa
ctggtcgccatcaagaaagtattgcaggacaagagatttaagaaccgagagctccagatc
atgagaaagctagaccactgtaacatagtccgattgcgttatttcttctactccagtggt
gagaagaaagatgaggtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgctccctgtgatttatgtcaagttg
tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatctgccatcgg
gatattaaaccgcagaatctcttgttggatcctgatacagccgtattaaaactctgtgac
tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagatgta
tggtctgctggctgtgtgttggctgagctgttactaggacaaccaatatttccaggggat
agtggtgtggatcagttggtagaaataatcaaggtcctgggaactccaacaagggagcaa
atcagagaaatgaacccaaactacacagaatttaaattccctcaaattaaggcacatcct
tggactaaggattcgtcaggaacaggacatttcacctcaggagtgcgggtcttccgaccc
cgaactccaccggaggcaattgcactgtgtagccgtctgctggagtatacaccaactgcc
cgactaacaccactggaagcttgtgcacattcattttttgatgaattacgggacccaaat
gtcaaactaccaaatgggcgagacacacctgcactcttcaacttcaccactcaagaactg
tcaagtaatccacctctggctaccatccttattcctcctcatgctcggattcaagcagct
gcttcaacccccacaaatgccacagcagcctcagatgctaatactggagaccgtggacag
accaataatgctgcttctgcatcagcttccaactccacctga
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