Pongo abelii (Sumatran orangutan): 100448382
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Entry
100448382 CDS
T01416
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
KO
K04433
mitogen-activated protein kinase kinase 6 [EC:
2.7.12.2
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04010
MAPK signaling pathway
pon04015
Rap1 signaling pathway
pon04218
Cellular senescence
pon04380
Osteoclast differentiation
pon04620
Toll-like receptor signaling pathway
pon04664
Fc epsilon RI signaling pathway
pon04668
TNF signaling pathway
pon04750
Inflammatory mediator regulation of TRP channels
pon04912
GnRH signaling pathway
pon04935
Growth hormone synthesis, secretion and action
pon04936
Alcoholic liver disease
pon05014
Amyotrophic lateral sclerosis
pon05022
Pathways of neurodegeneration - multiple diseases
pon05132
Salmonella infection
pon05135
Yersinia infection
pon05145
Toxoplasmosis
pon05161
Hepatitis B
pon05163
Human cytomegalovirus infection
pon05167
Kaposi sarcoma-associated herpesvirus infection
pon05169
Epstein-Barr virus infection
pon05170
Human immunodeficiency virus 1 infection
pon05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pon05417
Lipid and atherosclerosis
pon05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100448382 (MAP2K6)
04015 Rap1 signaling pathway
100448382 (MAP2K6)
04668 TNF signaling pathway
100448382 (MAP2K6)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
100448382 (MAP2K6)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100448382 (MAP2K6)
04664 Fc epsilon RI signaling pathway
100448382 (MAP2K6)
09152 Endocrine system
04912 GnRH signaling pathway
100448382 (MAP2K6)
04935 Growth hormone synthesis, secretion and action
100448382 (MAP2K6)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100448382 (MAP2K6)
09158 Development and regeneration
04380 Osteoclast differentiation
100448382 (MAP2K6)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100448382 (MAP2K6)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100448382 (MAP2K6)
05161 Hepatitis B
100448382 (MAP2K6)
05163 Human cytomegalovirus infection
100448382 (MAP2K6)
05167 Kaposi sarcoma-associated herpesvirus infection
100448382 (MAP2K6)
05169 Epstein-Barr virus infection
100448382 (MAP2K6)
09171 Infectious disease: bacterial
05132 Salmonella infection
100448382 (MAP2K6)
05135 Yersinia infection
100448382 (MAP2K6)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100448382 (MAP2K6)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100448382 (MAP2K6)
05022 Pathways of neurodegeneration - multiple diseases
100448382 (MAP2K6)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100448382 (MAP2K6)
05418 Fluid shear stress and atherosclerosis
100448382 (MAP2K6)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100448382 (MAP2K6)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100448382 (MAP2K6)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.2 mitogen-activated protein kinase kinase
100448382 (MAP2K6)
Protein kinases [BR:
pon01001
]
Serine/threonine kinases: STE group
STE7 family
100448382 (MAP2K6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
ABC1
Pkinase_fungal
Seadorna_VP7
Haspin_kinase
Choline_kinase
DUF4344
APH
Motif
Other DBs
NCBI-GeneID:
100448382
NCBI-ProteinID:
XP_002827807
Ensembl:
ENSPPYG00000008579
UniProt:
H2NUJ7
LinkDB
All DBs
Position
19:84769870..84908605
Genome browser
AA seq
334 aa
AA seq
DB search
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
NT seq
1005 nt
NT seq
+upstream
nt +downstream
nt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagaccagttccacaccacctcgagatttagactccaaggcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgacctggagcctataatggaactggga
cgaggtgcgtacggggtggtggagaagatgcggcacgtgcccagcgggcagatcatggca
gtgaagcggatccgagctacagtaaatagccaggaacagaaacggctactgatggatttg
gatatttccatgaggacggtggactgtccattcactgtcaccttttatggtgcactgttt
cgggagggtgatgtgtggatctgcatggagctcatggatacatcactagataaattctac
aaacaagttattgataaaggccagacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctgtctgtcattcacagagacgtc
aagccttctaatgtactcattaatgctctcggtcaagtgaagatgtgcgattttggaatc
agtggctacttggtggactctgttgctaaaacaattgatgcaggttgcaaaccatacatg
gcccctgaaagaataaacccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcacaatgattgagttggccatccttcgatttccctatgattcatgg
ggaactccatttcagcagctcaaacaggtggtagaggagccatcgccacaactcccagca
gacaagttctctgcagagtttgttgactttacctcacagtgcttaaagaagaattccaaa
gaacggcctacatacccagagctaatgcaacatccatttttcaccctacatgaatccaaa
ggaacagatgtggcatcttttgtaaaactgattcttggagactaa
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