Pongo abelii (Sumatran orangutan): 100457556
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Entry
100457556 CDS
T01416
Gene name
PAK4
Definition
(RefSeq) serine/threonine-protein kinase PAK 4 isoform X1
KO
K05734
p21-activated kinase 4 [EC:
2.7.11.1
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04012
ErbB signaling pathway
pon04014
Ras signaling pathway
pon04360
Axon guidance
pon04510
Focal adhesion
pon04660
T cell receptor signaling pathway
pon04810
Regulation of actin cytoskeleton
pon05170
Human immunodeficiency virus 1 infection
pon05206
MicroRNAs in cancer
pon05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100457556 (PAK4)
04014 Ras signaling pathway
100457556 (PAK4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100457556 (PAK4)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100457556 (PAK4)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
100457556 (PAK4)
09158 Development and regeneration
04360 Axon guidance
100457556 (PAK4)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100457556 (PAK4)
09162 Cancer: specific types
05211 Renal cell carcinoma
100457556 (PAK4)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100457556 (PAK4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100457556 (PAK4)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100457556 (PAK4)
Protein kinases [BR:
pon01001
]
Serine/threonine kinases: STE group
STE20 family
100457556 (PAK4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
Kinase-like
Pkinase_fungal
Kdo
KIND
hnRNP_Q_AcD
Motif
Other DBs
NCBI-GeneID:
100457556
NCBI-ProteinID:
XP_009230850
LinkDB
All DBs
Position
19
AA seq
598 aa
AA seq
DB search
MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT
SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARARQENGMPEE
LATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSSREGSGGPQESSRDKRPL
SGPDVGTPQPAGLASGAKLAAGRPFNTYPRADTDHPSRGAQGEPHDVAPNGPSAGGLAVP
QSSSSSSSRPPTRARGAPSPGVLGPHASEPQLAPPARTPATPAAPVAPAVPGPPGPCSPQ
REPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMD
LRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMN
EEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRK
SLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPP
RLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR
NT seq
1797 nt
NT seq
+upstream
nt +downstream
nt
atgtttgggaaaaggaagaagcgggtggagatctccgcgccatccaacttcgagcaccgc
gtgcacacgggcttcgatcagcacgagcagaagttcacggggctgccccgccagtggcag
agcctgatcgaggagtcggctcgccggcccaagcccctcgtcgaccccgcctgcatcacc
tccatccagcccggggcccccaagaccatcgtgcggggcagcaaaggtgccaaggatggg
gccctcacgctgctactggacgagtttgagaacatgtcggtgacacgctccaactccctg
cggagagacagcccgccgccgcccgcccgtgcccggcaggaaaatgggatgccagaggag
ctggccaccacggccagagggggcccggggaaggcaggcagccgaggccggttcgccggt
cacagcgaggcgggtggcggcagtggtgacaggcgacgggcggggccagagaagaggccc
aagtcttccagggagggctcaggggggccccaggagtcctcccgggacaaacgccccctc
tccgggcctgacgtcggcaccccccagcctgctggtctggccagtggggcgaaactggca
gctggccggccctttaacacctacccgagggctgacacggaccacccatcccggggtgcc
cagggggagcctcatgacgtggcccctaacgggccatcagcagggggcctggccgtcccc
cagtcctcctcctcctcctcctcccggcctcccacccgagcccgaggtgcccccagccct
ggagtactgggcccccacgcctcggagccccagctggcccctccagcccgcacccctgcc
acccctgccgcccctgtcgcccctgctgttcctgggccccctggcccctgctcaccacag
cgggagccacagcgagtatcccatgagcagttccgggctgccctgcagctggtggtggac
ccaggcgacccccgttcctacctggacaacttcatcaagatcggcgagggctccacgggc
atcgtgtgcatcgccaccgtgcgcagctcgggcaagctggtggccgtcaagaagatggac
ctgcgcaagcagcagaggcgcgagttgctcttcaacgaggtggtgatcatgagggactac
cagcacgagaatgtggtggagatgtacaacagctacctggtgggggacgagctctgggtg
gtcatggagttcctggaaggaggcgccctcaccgacatcgtcacccacaccaggatgaac
gaggagcagatcgcggccgtgtgcctggcagtgctgcaggccctgtcggtgctccacgcc
cagggcgtcatccaccgggacatcaagagtgactcaatcctgctgacccatgacggcagg
gtgaagctgtcagacttcgggttctgtgcccaggtgagcaaggaagtgccccgaaggaag
tcgctggtcggcacgccctactggatggccccagagctcatctcccgccttccctacggg
ccagaggtggacatctggtcgctggggataatggtgattgagatggtagacggagagccc
ccctacttcaacgagccacccctcaaagccatgaagatgattcgggacaacctgccaccc
cgactgaagaacctgcacaaggtgtcgccatccctgaagggcttcctggaccgcctgctg
gtgcgggaccctgcccagcgggccacggcagccgagctgctgaagcacccattcctggcc
aaggcagggccgcccgccagcatcgtgcccctcatgcgccagaaccgcaccagatga
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