KEGG   Panthera pardus (leopard): 109254368
Entry
109254368         CDS       T06062                                 
Symbol
VHL
Name
(RefSeq) von Hippel-Lindau disease tumor suppressor isoform X1
  KO
K03871  von Hippel-Lindau disease tumor supressor
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad04066  HIF-1 signaling pathway
ppad04120  Ubiquitin mediated proteolysis
ppad05200  Pathways in cancer
ppad05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    109254368 (VHL)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    109254368 (VHL)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109254368 (VHL)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    109254368 (VHL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:ppad04121]
    109254368 (VHL)
Ubiquitin system [BR:ppad04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul2 complex
    Target recognizing subunit
     109254368 (VHL)
SSDB
Motif
Pfam: VHL VHL_C Arm_vescicular
Other DBs
NCBI-GeneID: 109254368
NCBI-ProteinID: XP_019283731
Ensembl: ENSPPRG00000007193
UniProt: A0A9V1EKP0
LinkDB
Position
Unknown
AA seq 218 aa
MPRKAGNLEEAEAGVEEVDAEEVGPEEYGGEESGAEESGPEESDPEEPGAEEEMEAGQPR
PVLRSVNSCEPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFR
DAGTYDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDI
VRSLYEDLEDHPNVRKDLERLTQEHIENQRMEGETEMK
NT seq 657 nt   +upstreamnt  +downstreamnt
atgccccggaaggcagggaacttggaagaggccgaggccggtgtggaggaggtggacgcg
gaggaggtgggccctgaagagtacggcggggaggagtcgggcgccgaggagtctggcccg
gaagagtctgaccccgaggagccgggcgccgaggaggagatggaggctgggcagccgcga
ccggtgctacgctcagtgaactcttgcgagccgtctcaggtcatcttctgcaaccgcagt
ccgcgcgtcgtgctgccggtgtggctcaacttcgacggcgagccgcagccgtacccgaca
ctgccgcccggcacgggccgccgcatccatagctaccgaggtcacctttggcttttccga
gatgcaggaacatatgatgggcttctggttaaccaaactgaactatttgtgccatctctc
aatgttgatggacagcctatttttgccaacatcacactgccagtgtatactctgaaagag
cggtgcctccaggttgtccgaagcctagtcaagcctgagaattacaggagactggacatc
gtgagatcactctatgaagatctggaagaccatccgaatgtaaggaaagacctggagcgg
ctgacacaggagcatattgaaaaccagcggatggaaggggagactgaaatgaaatga

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