Pannonibacter phragmitetus: APZ00_14350
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Entry
APZ00_14350 CDS
T04214
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pphr
Pannonibacter phragmitetus
Pathway
pphr00300
Lysine biosynthesis
pphr00550
Peptidoglycan biosynthesis
pphr01100
Metabolic pathways
pphr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pphr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
APZ00_14350
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
APZ00_14350
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
APZ00_14350
Enzymes [BR:
pphr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
APZ00_14350
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ALV28095
UniProt:
A0A0U3EPF1
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Position
3122628..3124058
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AA seq
476 aa
AA seq
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MSAPLWTLDAFLAATRGEARGEPQAEITGISIDTRTILPGEAFVAIVGDRLDGHDYVAKA
LEAGASLALVARHKLVDLPQDGRYVVVDDPLEALRNLGRAARARTSARIVAVTGSVGKTG
TKEALRLALGRSGKVHASAASFNNHWGVPLTLARMPEDTEFGVFEIGMNHAGEITPLVQM
VRPHAAIITTVQAVHLEFFGSVEKIAQAKAEIFLGLEPGGLAILNQDNDQFDLLTFLAKT
AGVERIQTFGEAEGSDALLENYAVQTGSSSIQARVLGQEITYKIGAPGKHLVRNSLAVLL
AVCELGGDLALAGLALAELSAPKGRGAQTRLKLPGGEAVLVDESYNANPASMRAALSVLG
GMQAAAPGRKIAVLGDMLELGDAAGQLHADLIGPVEDSGADLVYCSGPLMRALWERLPRE
KRAVYAEHSEALTERLKDELRPGDIIMIKGSLGSRMGPLVDALKQEYPAADEMASA
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcaccgctctggaccctcgatgcctttctggccgcaacgcgcggcgaggcccgc
ggagagccgcaggctgaaatcaccggcatttccatcgacacccgcaccatcttgccgggc
gaagctttcgtcgccatcgtcggtgaccggctggacgggcatgattatgtggccaaggcc
ctcgaggctggcgcgtcgctggcgctggttgctcggcacaagctggtcgatctgccgcag
gatggccgctacgttgtggtggatgatccgcttgaggccctgcgcaatcttggacgtgcc
gcccgcgcgcgcaccagcgcccggatcgtggcggtcaccggctcggtcggcaagaccggc
accaaggaggcgctgcgcctcgcgcttggccgctccggcaaggtccatgcctcggccgcg
tccttcaacaatcactggggtgtgccgctgacgctggcgcgcatgccggaggataccgaa
ttcggtgtcttcgaaatcggcatgaaccatgccggagaaatcacgccgctggtgcagatg
gtccgcccgcatgcggccatcatcaccaccgtgcaggcggtgcatctggagtttttcggc
tcggtcgagaagatcgcacaggccaaggccgagatcttcctcgggctggagccgggcggc
cttgccattctcaatcaggacaatgaccagttcgacctgctgaccttccttgccaagacg
gctggtgtcgagcgtatccagaccttcggcgaagcggagggcagtgacgcgctgcttgag
aactatgcggtgcagaccgggtcctcttccattcaggcgcgggtgctggggcaggagatc
acctacaagatcggcgcgccgggcaagcaccttgtccgcaacagcctcgccgtgctgctg
gccgtctgcgaactcggcggcgatctggcgctggccggactggcactggccgagctctcg
gcccccaaggggcgcggcgcgcagacgcggctgaagctgccgggcggcgaggccgtgctg
gtcgatgaaagctacaacgccaatccggcctccatgcgcgcggccctcagcgtgcttggc
ggcatgcaggcggccgcgccgggccgcaagattgctgtgcttggcgacatgttggaactg
ggtgatgcagcggggcagttgcatgccgatctgattgggcccgtcgaagacagcggcgca
gatctggtctattgctccggcccgctgatgcgcgccttgtgggagcggctgccgcgcgag
aagcgcgccgtctatgccgagcattccgaagcgctgaccgagcgcctcaaggatgagctg
cgccctggcgacatcatcatgatcaaaggctctctcgggagccgaatgggcccccttgtg
gacgcgctcaagcaggaatatcccgcagcggatgaaatggcttcggcctga
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