KEGG   Pan paniscus (bonobo): 100995134
Entry
100995134         CDS       T02283                                 

Gene name
ADCY3
Definition
(RefSeq) adenylate cyclase 3
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps00230  Purine metabolism
pps01100  Metabolic pathways
pps01522  Endocrine resistance
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04022  cGMP-PKG signaling pathway
pps04024  cAMP signaling pathway
pps04062  Chemokine signaling pathway
pps04072  Phospholipase D signaling pathway
pps04114  Oocyte meiosis
pps04211  Longevity regulating pathway
pps04213  Longevity regulating pathway - multiple species
pps04261  Adrenergic signaling in cardiomyocytes
pps04270  Vascular smooth muscle contraction
pps04371  Apelin signaling pathway
pps04540  Gap junction
pps04611  Platelet activation
pps04713  Circadian entrainment
pps04714  Thermogenesis
pps04723  Retrograde endocannabinoid signaling
pps04724  Glutamatergic synapse
pps04725  Cholinergic synapse
pps04727  GABAergic synapse
pps04740  Olfactory transduction
pps04750  Inflammatory mediator regulation of TRP channels
pps04911  Insulin secretion
pps04912  GnRH signaling pathway
pps04913  Ovarian steroidogenesis
pps04914  Progesterone-mediated oocyte maturation
pps04915  Estrogen signaling pathway
pps04916  Melanogenesis
pps04918  Thyroid hormone synthesis
pps04921  Oxytocin signaling pathway
pps04923  Regulation of lipolysis in adipocytes
pps04925  Aldosterone synthesis and secretion
pps04926  Relaxin signaling pathway
pps04927  Cortisol synthesis and secretion
pps04928  Parathyroid hormone synthesis, secretion and action
pps04934  Cushing syndrome
pps04935  Growth hormone synthesis, secretion and action
pps04962  Vasopressin-regulated water reabsorption
pps04970  Salivary secretion
pps04971  Gastric acid secretion
pps04972  Pancreatic secretion
pps04976  Bile secretion
pps05032  Morphine addiction
pps05163  Human cytomegalovirus infection
pps05166  Human T-cell leukemia virus 1 infection
pps05200  Pathways in cancer
pps05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pps00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100995134 (ADCY3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100995134 (ADCY3)
   04371 Apelin signaling pathway
    100995134 (ADCY3)
   04020 Calcium signaling pathway
    100995134 (ADCY3)
   04072 Phospholipase D signaling pathway
    100995134 (ADCY3)
   04024 cAMP signaling pathway
    100995134 (ADCY3)
   04022 cGMP-PKG signaling pathway
    100995134 (ADCY3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100995134 (ADCY3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100995134 (ADCY3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100995134 (ADCY3)
   04062 Chemokine signaling pathway
    100995134 (ADCY3)
  09152 Endocrine system
   04911 Insulin secretion
    100995134 (ADCY3)
   04923 Regulation of lipolysis in adipocytes
    100995134 (ADCY3)
   04912 GnRH signaling pathway
    100995134 (ADCY3)
   04913 Ovarian steroidogenesis
    100995134 (ADCY3)
   04915 Estrogen signaling pathway
    100995134 (ADCY3)
   04914 Progesterone-mediated oocyte maturation
    100995134 (ADCY3)
   04921 Oxytocin signaling pathway
    100995134 (ADCY3)
   04926 Relaxin signaling pathway
    100995134 (ADCY3)
   04935 Growth hormone synthesis, secretion and action
    100995134 (ADCY3)
   04918 Thyroid hormone synthesis
    100995134 (ADCY3)
   04928 Parathyroid hormone synthesis, secretion and action
    100995134 (ADCY3)
   04916 Melanogenesis
    100995134 (ADCY3)
   04925 Aldosterone synthesis and secretion
    100995134 (ADCY3)
   04927 Cortisol synthesis and secretion
    100995134 (ADCY3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100995134 (ADCY3)
   04270 Vascular smooth muscle contraction
    100995134 (ADCY3)
  09154 Digestive system
   04970 Salivary secretion
    100995134 (ADCY3)
   04971 Gastric acid secretion
    100995134 (ADCY3)
   04972 Pancreatic secretion
    100995134 (ADCY3)
   04976 Bile secretion
    100995134 (ADCY3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    100995134 (ADCY3)
  09156 Nervous system
   04724 Glutamatergic synapse
    100995134 (ADCY3)
   04727 GABAergic synapse
    100995134 (ADCY3)
   04725 Cholinergic synapse
    100995134 (ADCY3)
   04723 Retrograde endocannabinoid signaling
    100995134 (ADCY3)
  09157 Sensory system
   04740 Olfactory transduction
    100995134 (ADCY3)
   04750 Inflammatory mediator regulation of TRP channels
    100995134 (ADCY3)
  09149 Aging
   04211 Longevity regulating pathway
    100995134 (ADCY3)
   04213 Longevity regulating pathway - multiple species
    100995134 (ADCY3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100995134 (ADCY3)
   04714 Thermogenesis
    100995134 (ADCY3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100995134 (ADCY3)
  09165 Substance dependence
   05032 Morphine addiction
    100995134 (ADCY3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100995134 (ADCY3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100995134 (ADCY3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100995134 (ADCY3)
   05163 Human cytomegalovirus infection
    100995134 (ADCY3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100995134 (ADCY3)
Enzymes [BR:pps01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100995134 (ADCY3)
SSDB
Motif
Pfam: Guanylate_cyc AC_N HNOBA RAP1 OPA3 Peptidase_S49_N
Other DBs
NCBI-GeneID: 100995134
NCBI-ProteinID: XP_008950647
UniProt: A0A2R9BLU9
LinkDB
Position
2A
AA seq 1145 aa
MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLAVAGIGLVLDII
LFVLCKKGLLPDRVTRRVVPYVLWLLITAQIFSYLGLNFARAHAASDTVGWQVFFVFSFF
ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQEELKGMQLLREILANVFLYLCAIAVG
IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES
QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ
LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV
LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCD
YLEEKGIETYLIIASKPEVKKTATQNGLNGSALPNGAPASSKSSSPALIETKEPNGSAHS
SGSTSEKPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA
QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTN
YVTFMVGEILLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN
VVDMLSCLQYYTGPGNATAGMETEGSCLENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM
LLVAGAVATINLYAWRPVFDEYDHKRFREHDLPMVALEQMQGFNPGLNGTDSRLPLVPSK
YSMTVMVFLMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH
VARHFLGSKKRDEELYSQTYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF
DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFASSNKEDKSERERWQHLADLADF
ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV
MGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGPSVTLPHQ
VVDNS
NT seq 3438 nt   +upstreamnt  +downstreamnt
atgccgaggaaccagggcttctccgagcccgaatactcggccgagtactcagccgagtac
tccgtcagcctgccctccgaccctgaccgcggggtgggccggacccatgaaatctcggtc
cggaactcgggctcctgcctgtgcctgcctcgcttcatgcggctgactttcgtgccggag
tccttggagaacctctaccagacctacttcaaaaggcagcgccacgagaccctgctggtg
ctggtggtctttgcagccctctttgactgctacgtggtggtcatgtgtgctgtggtcttc
tccagcgacaagctggctcccctcgccgtggctggaattggactggtgttggacatcatc
ctcttcgtgctctgcaaaaaggggctgctcccggaccgggtcacccgcagagtggtgccc
tacgtgctgtggctgctcataaccgcccagatcttctcctacctgggcctgaacttcgcg
cgtgcccacgcggctagtgacacggtgggctggcaggtcttctttgtcttctccttcttc
atcacgctgcccctcagcctcagccccatcgtgatcatctccgtggtctcctgtgtggtg
cacacgttggtcctgggggtcaccgtggcccagcagcagcaggaggagctcaaggggatg
cagctgctgcgggagatcctggccaacgtcttcctctacctgtgcgccatcgctgtgggc
atcatgtcctactacatggctgaccgcaagcaccgcaaggccttcctggaggcccgccag
tcgctggaggtgaagatgaacctggaagagcagagccagcagcaggagaacctcatgctt
tccatcctgcccaagcacgtggctgacgagatgctgaaagacatgaagaaagacgagagc
cagaaggaccagcagcagttcaacaccatgtacatgtaccgtcacgagaacgtcagcatc
ctctttgccgacattgtgggctttactcagctgtcttctgcctgcagtgcccaggagctt
gtgaagctgctcaacgagctctttgcccgctttgacaagctggcagctaaataccaccag
ctgaggattaagatcctgggcgactgctactactgcatctgcggcttgcctgactaccgg
gaggaccacgccgtctgctccatcctcatggggctggccatggtggaggccatctcgtat
gtgcgggagaagaccaagactggggtggacatgcgtgtgggggtgcacacgggcaccgtg
ctggggggcgtcctgggccagaagcgctggcagtacgacgtgtggtcgactgatgtcact
gtagccaacaagatggaggccggcggcatccctgggcgcgtgcacatctcccagagcacc
atggactgcctgaaaggggagtttgatgtggagccaggcgatgggggcagccgctgtgat
tacctagaagagaagggtattgaaacctacctcatcattgcctccaagccagaggtgaag
aaaacagccacccagaatggcctcaatggctcggccctgcccaatggagcaccagcttcc
tcaaagtccagctcccctgccctcattgagaccaaggagcccaacgggagtgcccacagc
agcgggtccacgtcggagaagcccgaggagcaggatgcccaggccgacaacccctcattc
cccaacccacgccggaggctgcgcctgcaggacctggctgaccgagtggtggatgcctct
gaagatgagcacgagctcaaccagctgctcaacgaggccctgcttgagcgagagtccgcc
caagtagtaaagaagagaaacaccttcctcttgtccatgcggttcatggaccccgagatg
gaaacccgctactcggtggagaaggagaagcagagtggggctgccttcagctgctcctgc
gtcgtcctgctctgcacggccctggtcgagatactcatcgacccctggctaatgacaaac
tatgtgaccttcatggtgggggagattctgctcctcatcctgaccatctgctccctggct
gccatctttccccgggcctttcctaagaagcttgtggccttctcaacttggattgaccgg
acccgctgggccaggaacacctgggccatgctcgccatcttcatcctggtgatggcaaat
gtcgtggacatgctcagctgtctccagtactacacgggacccggcaatgcaacggcaggg
atggagacggagggcagctgcctggagaaccccaagtattacaactatgtggccgtgctg
tccctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacgctcatg
ctgctcgtcgcaggcgccgtggccaccatcaacctctatgcctggcgccccgtctttgat
gaatacgaccacaagcgttttcgggagcacgacttacctatggtggccttagagcagatg
caaggattcaaccctgggctcaatggcactgacagcaggctgcccctggtgccttccaag
tactctatgacggtgatggtgttcctcatgatgctcagcttctactacttctcccgccac
gtagaaaagctggcacggacacttttcttgtggaagattgaggtccacgaccagaaggaa
cgtgtctatgagatgcgacgctggaacgaggccttggtcaccaacatgttgcctgagcac
gtggcacgccatttcctggggtccaagaagagagatgaggagctgtatagccagacgtat
gatgagattggagtcatgtttgcctccctgcccaactttgctgacttctacacagaggag
agcatcaacaatggtggtattgagtgtctgcgtttcctcaatgaaatcatctcggatttt
gactctctcctggacaatcccaagttccgggtgatcaccaagatcaaaaccattggcagc
acgtatatggcggcttcaggagtcacccccgatgtcaacaccaatggctttgccagctcc
aacaaggaagacaagtccgagagagagcgctggcagcacctggctgacctggccgacttc
gcgctggccatgaaggatacgctcaccaacatcaacaaccagtccttcaataacttcatg
ctgcgcataggcatgaacaaaggcggggttctggctggggtcatcggagcccggaaacca
cactacgacatctggggcaatacagtcaatgtagccagcaggatggagtccacgggggtc
atgggcaacattcaggtggtagaagaaacccaagtcatcctccgagagtacggcttccgc
tttgtgaggcgaggccccatctttgtgaaggggaagggggagctgctgaccttcttcttg
aaggggcgggataagctagccaccttccccaatggcccctctgtcacactgccccaccag
gtggtggacaactcctga

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