KEGG   Piliocolobus tephrosceles (Ugandan red Colobus): 111532954
Entry
111532954         CDS       T07491                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
pteh  Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh01522  Endocrine resistance
pteh04010  MAPK signaling pathway
pteh04015  Rap1 signaling pathway
pteh04068  FoxO signaling pathway
pteh04071  Sphingolipid signaling pathway
pteh04114  Oocyte meiosis
pteh04148  Efferocytosis
pteh04218  Cellular senescence
pteh04261  Adrenergic signaling in cardiomyocytes
pteh04370  VEGF signaling pathway
pteh04380  Osteoclast differentiation
pteh04550  Signaling pathways regulating pluripotency of stem cells
pteh04611  Platelet activation
pteh04613  Neutrophil extracellular trap formation
pteh04620  Toll-like receptor signaling pathway
pteh04621  NOD-like receptor signaling pathway
pteh04622  RIG-I-like receptor signaling pathway
pteh04625  C-type lectin receptor signaling pathway
pteh04657  IL-17 signaling pathway
pteh04658  Th1 and Th2 cell differentiation
pteh04659  Th17 cell differentiation
pteh04660  T cell receptor signaling pathway
pteh04664  Fc epsilon RI signaling pathway
pteh04668  TNF signaling pathway
pteh04670  Leukocyte transendothelial migration
pteh04714  Thermogenesis
pteh04722  Neurotrophin signaling pathway
pteh04723  Retrograde endocannabinoid signaling
pteh04728  Dopaminergic synapse
pteh04750  Inflammatory mediator regulation of TRP channels
pteh04912  GnRH signaling pathway
pteh04914  Progesterone-mediated oocyte maturation
pteh04917  Prolactin signaling pathway
pteh04926  Relaxin signaling pathway
pteh04932  Non-alcoholic fatty liver disease
pteh04933  AGE-RAGE signaling pathway in diabetic complications
pteh04935  Growth hormone synthesis, secretion and action
pteh04936  Alcoholic liver disease
pteh05014  Amyotrophic lateral sclerosis
pteh05020  Prion disease
pteh05022  Pathways of neurodegeneration - multiple diseases
pteh05132  Salmonella infection
pteh05133  Pertussis
pteh05135  Yersinia infection
pteh05140  Leishmaniasis
pteh05142  Chagas disease
pteh05145  Toxoplasmosis
pteh05152  Tuberculosis
pteh05161  Hepatitis B
pteh05163  Human cytomegalovirus infection
pteh05167  Kaposi sarcoma-associated herpesvirus infection
pteh05169  Epstein-Barr virus infection
pteh05170  Human immunodeficiency virus 1 infection
pteh05171  Coronavirus disease - COVID-19
pteh05205  Proteoglycans in cancer
pteh05208  Chemical carcinogenesis - reactive oxygen species
pteh05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pteh05415  Diabetic cardiomyopathy
pteh05417  Lipid and atherosclerosis
pteh05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pteh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111532954 (MAPK12)
   04015 Rap1 signaling pathway
    111532954 (MAPK12)
   04370 VEGF signaling pathway
    111532954 (MAPK12)
   04668 TNF signaling pathway
    111532954 (MAPK12)
   04068 FoxO signaling pathway
    111532954 (MAPK12)
   04071 Sphingolipid signaling pathway
    111532954 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    111532954 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    111532954 (MAPK12)
   04218 Cellular senescence
    111532954 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    111532954 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    111532954 (MAPK12)
   04613 Neutrophil extracellular trap formation
    111532954 (MAPK12)
   04620 Toll-like receptor signaling pathway
    111532954 (MAPK12)
   04621 NOD-like receptor signaling pathway
    111532954 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    111532954 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    111532954 (MAPK12)
   04660 T cell receptor signaling pathway
    111532954 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    111532954 (MAPK12)
   04659 Th17 cell differentiation
    111532954 (MAPK12)
   04657 IL-17 signaling pathway
    111532954 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    111532954 (MAPK12)
   04670 Leukocyte transendothelial migration
    111532954 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    111532954 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    111532954 (MAPK12)
   04917 Prolactin signaling pathway
    111532954 (MAPK12)
   04926 Relaxin signaling pathway
    111532954 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    111532954 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    111532954 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    111532954 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    111532954 (MAPK12)
   04722 Neurotrophin signaling pathway
    111532954 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    111532954 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    111532954 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    111532954 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    111532954 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    111532954 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    111532954 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111532954 (MAPK12)
   05161 Hepatitis B
    111532954 (MAPK12)
   05171 Coronavirus disease - COVID-19
    111532954 (MAPK12)
   05163 Human cytomegalovirus infection
    111532954 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111532954 (MAPK12)
   05169 Epstein-Barr virus infection
    111532954 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    111532954 (MAPK12)
   05135 Yersinia infection
    111532954 (MAPK12)
   05133 Pertussis
    111532954 (MAPK12)
   05152 Tuberculosis
    111532954 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    111532954 (MAPK12)
   05140 Leishmaniasis
    111532954 (MAPK12)
   05142 Chagas disease
    111532954 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    111532954 (MAPK12)
   05020 Prion disease
    111532954 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    111532954 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    111532954 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    111532954 (MAPK12)
   05415 Diabetic cardiomyopathy
    111532954 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    111532954 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    111532954 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    111532954 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    111532954 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pteh01001]
    111532954 (MAPK12)
Enzymes [BR:pteh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     111532954 (MAPK12)
Protein kinases [BR:pteh01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   111532954 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Kinase-like UvrD_C Haspin_kinase
Other DBs
NCBI-GeneID: 111532954
NCBI-ProteinID: XP_026303934
Ensembl: ENSPTEG00000007490
LinkDB
Position
19:complement(32217826..32232236)
AA seq 367 aa
MSSPPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRV
TAAEALAHPYFESLHDTEDEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAR
VSKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctctccgccgcctgcccgcagtggcttttaccgccaggaggtgaccaagacggcc
tgggaggtgcgcgccgtgtaccgggacctgcagcccgtgggctcgggcgcctatggcgcg
gtgtgctcggcggtggacagccgcaccggcgctaaggtggccatcaagaagctgtatcgg
cccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagcac
atgcgccacgagaacgtgattgggctgctggacgtattcactcctgatgagaccctggat
gacttcacagacttttacctggtgatgccgttcatgggcaccgacctgggcaagctcatg
aaacatgagaagctgggcgaggaccggatccagttcctcgtgtaccagatgctgaagggg
ttgaggtatatccatgctgccggcatcatccacagagacctgaagcctggcaacctggct
gtgaacgaagactgtgagctgaagatcctggactttggcctggccaggcaggcagacagc
gagatgactgggtatgtggtgacccggtggtaccgggcacccgaggtcatcttgaattgg
atgcgctacacgcagacggtggacatctggtctgtgggctgcatcatggcggagatgatc
acaggcaagacgctgttcaagggcagcgaccacctggaccagctgaaggagatcatgaag
gtgacagggacgcctccagctgagtttgtgcagcggctgcagagtgatgaggccaagaac
tacatgaagggcctccccgagctggagaagaaggattttgcctccatcctgaccaatgca
agccctctggctgtgaacctcctggagaagatgctggtgctggatgcggagcagcgggtg
acagcagccgaggcactggcccatccctacttcgagtccctgcacgacacggaagatgag
ccccaggtccagaagtatgacgactcttttgatgacgtggaccgcacgctggatgaatgg
aagcgtgttacttacaaagaggtgctcagcttcaagcctccccggcagctgggagccagg
gtctccaaggagacggctctgtga

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