Rousettus aegyptiacus (Egyptian rousette): 107501487
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Entry
107501487 CDS
T06036
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00260
Glycine, serine and threonine metabolism
ray00630
Glyoxylate and dicarboxylate metabolism
ray00670
One carbon pool by folate
ray01100
Metabolic pathways
ray01200
Carbon metabolism
ray01230
Biosynthesis of amino acids
ray01240
Biosynthesis of cofactors
ray01523
Antifolate resistance
Module
ray_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
107501487 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
107501487 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
107501487 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
107501487 (SHMT2)
Enzymes [BR:
ray01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
107501487 (SHMT2)
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Ortholog
Paralog
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
107501487
NCBI-ProteinID:
XP_015983166
UniProt:
A0A7J8JN48
LinkDB
All DBs
Position
Unknown
AA seq
504 aa
AA seq
DB search
MLPFSLIWATRPLQRCGQLARMAIRCQHNEAAQNQTTEATRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPKTGLIDYDQLAVTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAARVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGVQSVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQASTPMFREYSLQVLKNARA
MADALLDRGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITTNKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDAETRH
QLADLRQRVEQFARAFPMPGFEEH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttaatctgggcgactcggcctctgcagagatgtggtcagctggcc
aggatggcgatacggtgccagcacaatgaggcggcccagaaccagaccacagaagcaacc
aggggctggacaggccaggagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagggagaaggacaggcagtgtcgtggtctggaactcattgcctcagagaacttttgc
agccgagctgcgctggaggccttggggtcctgtctgaacaacaagtactctgagggttat
cctggcaagagatattatgggggagcagaagtagtggatgaaatcgagctgttgtgtcag
cgccgggccttggaagcatttgacctggatcctgcacagtggggagtcaatgtccagccc
tactcagggtccccagccaatctggccgcctatacagcccttctgcagcctcatgaccga
atcatggggctggacctgcctgatgggggccacctcacccatggctatatgtctgatgtc
aagcggatctcagctacatccatcttcttcgagtctatgccttataagctgaatcccaaa
actggccttattgactacgaccagctggcagtcactgctcgacttttccggcctcggctt
atcatagctggcaccagcgcctatgctcgcctcatcgactatgcccgaatgagagaggtt
tgtgatgaggtcaaggcacaccttctggcagacatggcccacatcagtggcttggtggct
gccagggtgatcccctcacctttcaagcatgcggatgttgtcaccactaccacccacaag
acccttcgaggggccaggtcaggactcatcttctaccggaagggggtgcagtctgtggac
cccaagactggccgggagatcccttacacgtttgaggaccgaatcaactttgctgtgttc
ccatcactgcagggggggccccacaaccatgccattgctgcagtggccgtggctctaaag
caggccagtacccccatgttccgggagtactctctgcaggttctgaagaacgctcgggcc
atggctgatgccctgctagatcgaggctactcactggtgtctggtggcactgacaaccat
ctagtactggtggacctgcggccaaagggcctggatggggctcgggccgagcgggtactg
gagcttgtatccatcacaaccaacaagaacacttgtcctggagaccgaagtgccatcaca
ccggggggccttcggctcggggccccagccttgacctctcgacagtttcgtgaagatgac
ttccggagagttgtggactttatagatgaaggcgtcaacattggcttggaggtgaagagc
aagaccgccaaactccaggatttcaaatccttcctgctcaaggatgcagaaacaagacat
cagctggctgacctcaggcaacgggtggaacagtttgccagggcatttcctatgcctggt
tttgaagagcactga
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