Rhodococcus sp. PBTS 1: A3Q40_01212
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Entry
A3Q40_01212 CDS
T05182
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rhu
Rhodococcus sp. PBTS 1
Pathway
rhu00300
Lysine biosynthesis
rhu00550
Peptidoglycan biosynthesis
rhu01100
Metabolic pathways
rhu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rhu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A3Q40_01212 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A3Q40_01212 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A3Q40_01212 (murF)
Enzymes [BR:
rhu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A3Q40_01212 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AMY18605
UniProt:
A0A143Q5Q7
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All DBs
Position
1318070..1319551
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AA seq
493 aa
AA seq
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MRALSIGEIADIVGGTLHDVPDPDVRVTGTVEFDSRKVTAGGVFLALPGERVDGHDHAAD
AVAAGAVVVLATRPVGVPAVVVEPTPRPDLPAYDPTGAGPAVLAALAALASASVTGLIEN
GLTVVGITGSSGKTSTKDLIRAVLERAGTVVAPPGSFNNELGHPWTVLRADETTRFLVLE
LSARGRGHIAELARIAPPRIGVELNVGTAHLGEFGSRENIAEAKSELVQALPAAADGGVA
VLNADDRLVAAMAEKTTARVVTYGHGGSADVRATDVVLDAEARASFTLHTASGSAPVALQ
VHGEHQVSNALSAAAVGLECGMALDDIAAALGDARAASERRMDVRTRPDGVTVINDSYNA
NPDSVRAALKALVTMARADRRSARRSWAVLGEMAELGEDSVIEHDRIGRLAVRLAVDKLV
VVGTGRPSHGMHQGAVMEGSWGDESVLVPDADAAVELLREQVAPGDLVLVKASQSVRLWT
VAEAVLAEQGENR
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgagagcactgtcgatcggggagatcgcggacatcgtcggagggactctgcacgacgtg
ccggatccggacgtccgggtcacgggcacggtggagttcgactcccggaaggtgaccgcg
ggcggagtgttcctcgccctgccgggtgagcgggtcgacggccacgatcacgccgccgac
gccgtcgcggccggcgcggtcgtggtgctggcgacgcggccggtgggtgtccccgccgtc
gtcgtcgagccgaccccgcgcccggacctgcccgcgtacgacccgaccggagcgggaccc
gccgtgctggcggcgctcgccgcgctggcgtccgcgtcggtgaccggactgatcgagaac
gggctgaccgtcgtcggcatcaccgggtcctcgggcaagacgtccaccaaggacctgatc
cgggcggtcctcgagcgggcgggcaccgtggtggccccgccgggctcgttcaacaacgaa
ctcggccacccgtggacggtgctgcgggcggacgagaccacccgattcctcgttctggag
ctctcggcgcgcgggcgcgggcacatcgccgagctggcccggatcgcgccgccgcgcatc
ggcgtcgagctcaacgtgggcaccgcgcacctcggggagttcgggtcgcgcgagaacatc
gcggaggccaagtccgagctggtccaggccctgcctgccgccgccgacggcggcgtggcc
gtcctcaatgccgacgaccggctcgtggcggcgatggccgagaagaccaccgcacgcgtc
gtcacctacggccacggcggcagcgccgacgtgcgcgcgacggacgtcgtcctcgacgcg
gaagcgcgcgcgtcgttcacgctgcacacggcgtccgggtccgccccggtcgccttgcag
gtgcacggcgagcaccaggtctcgaacgccctgtcggccgcggccgtcggactcgagtgc
gggatggctctcgacgacatcgcggccgcgctgggcgacgcccgcgccgcgtcggagcgg
cgcatggacgtgcgcacccgcccggacggcgtcacggtgatcaacgattcctacaacgcc
aaccccgattcggtgcgcgccgccctcaaggccctggtcacgatggcccgcgccgatcgc
agaagcgcgcggcgctcctgggcggtgctcggggagatggcggagctgggcgaggactcc
gtgatcgaacacgaccggatcggccgactggccgtgcggttggcggtggacaagctggtg
gtcgtggggaccgggcgtccctcgcacggcatgcaccagggcgcggtcatggaagggtcc
tggggcgacgagtcggtgctggttcccgacgccgacgcggcggtcgagctgctgcgcgag
caggtggcgccgggtgatctggtgttggtcaaggcatcgcagtcggtgcggctgtggacc
gtcgcggaggcggtcctcgcggagcagggggagaaccggtga
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