Rattus norvegicus (rat): 25267
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Entry
25267 CDS
T01003
Gene name
Pdgfra, APDGFR, PDGFACE
Definition
(RefSeq) platelet derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01521
EGFR tyrosine kinase inhibitor resistance
rno04010
MAPK signaling pathway
rno04014
Ras signaling pathway
rno04015
Rap1 signaling pathway
rno04020
Calcium signaling pathway
rno04072
Phospholipase D signaling pathway
rno04144
Endocytosis
rno04151
PI3K-Akt signaling pathway
rno04510
Focal adhesion
rno04540
Gap junction
rno04630
JAK-STAT signaling pathway
rno04810
Regulation of actin cytoskeleton
rno05163
Human cytomegalovirus infection
rno05200
Pathways in cancer
rno05206
MicroRNAs in cancer
rno05214
Glioma
rno05215
Prostate cancer
rno05218
Melanoma
rno05230
Central carbon metabolism in cancer
rno05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
25267 (Pdgfra)
04014 Ras signaling pathway
25267 (Pdgfra)
04015 Rap1 signaling pathway
25267 (Pdgfra)
04630 JAK-STAT signaling pathway
25267 (Pdgfra)
04020 Calcium signaling pathway
25267 (Pdgfra)
04072 Phospholipase D signaling pathway
25267 (Pdgfra)
04151 PI3K-Akt signaling pathway
25267 (Pdgfra)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
25267 (Pdgfra)
09144 Cellular community - eukaryotes
04510 Focal adhesion
25267 (Pdgfra)
04540 Gap junction
25267 (Pdgfra)
09142 Cell motility
04810 Regulation of actin cytoskeleton
25267 (Pdgfra)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
25267 (Pdgfra)
05206 MicroRNAs in cancer
25267 (Pdgfra)
05230 Central carbon metabolism in cancer
25267 (Pdgfra)
05231 Choline metabolism in cancer
25267 (Pdgfra)
09162 Cancer: specific types
05214 Glioma
25267 (Pdgfra)
05218 Melanoma
25267 (Pdgfra)
05215 Prostate cancer
25267 (Pdgfra)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
25267 (Pdgfra)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
25267 (Pdgfra)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
25267 (Pdgfra)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
rno04090
]
25267 (Pdgfra)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
25267 (Pdgfra)
Protein kinases [BR:
rno01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
25267 (Pdgfra)
CD molecules [BR:
rno04090
]
Proteins
25267 (Pdgfra)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
V-set
Herpes_gE
C2-set_2
Motif
Other DBs
NCBI-GeneID:
25267
NCBI-ProteinID:
NP_036934
RGD:
3284
Ensembl:
ENSRNOG00000002244
UniProt:
P20786
G3V6A0
LinkDB
All DBs
Position
14p11
AA seq
1088 aa
AA seq
DB search
MGTSQAFLVLSCLLTGPSLIVCQLLLPSILPNENEKIVPLSSSFSLRCFGESEVSWQHPM
SEEEDPNVEIRTEENNSSLFVTVLEVVNASAAHTGWYTCYYNHTQTEESEIEGRHIYIYV
PDPDMAFVPLGMTDSLVIVEEDDSAIIPCRTTDPDTEVTLHNNGRLVPASYDSRQGFNGT
FSVGPYICEATVRGRTFKTSEFNVYALKATSELNLEMDTRQTVYKAGETIVVTCAVFNNE
VVDLQWTYPGEVRNKGITMLEEIKLPSIKLVYTLTVPKATVKDSGDYECAARQATKEVKE
MKTVTISVHEKGFVQIRPTFGHLETVNLHQVREFVVEVQAYPTPRISWLKDNLTLIENLT
EITTDVQRSQETRYQSKLKLIRAKEEDSGHYTIIVQNDDDMKSYTFELSTLVPASILELV
DDHHGSGGGQTVRCTAEGTPLPNIEWMICKDIKKCNNDTSWTVLASNVSNIITEFHQRGR
STVEGRVSFAKVEETIAVRCLAKNDLGIGNRELKLVAPTLRSELTVAAAVLVLLVIVIVS
LIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGS
GAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLL
GACTKSGPIYIITEYCFYGDLVNYLHKNRDSFMSRHPEKPKKDLDIFGLNPADESTRSYV
ILSFENNGDYVDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEAKNL
LSDDDSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLAR
DIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGVLLWEIFSLGGTPYPGMMV
DSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKKS
YEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKEWEGGLDEQRLSADSGYIIP
LPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSS
DLVEDSFL
NT seq
3267 nt
NT seq
+upstream
nt +downstream
nt
atggggacctcccaggcctttctggtcctcagctgtctcctcacagggccgagcctcatc
gtctgccagctcttattaccctccatccttccaaatgagaatgagaagattgtgccgctg
agttcgtccttctctctgagatgcttcggggagagcgaagtgagctggcagcaccccatg
tctgaagaagaggaccccaacgtggaaatcagaaccgaggagaacaacagtagcctcttt
gtcacggtgctggaagtggtcaacgcctcagcggcccacaccggatggtacacttgctat
tacaaccacactcagacagaagagagtgagatcgaaggcaggcacatttatatctatgta
ccagacccagacatggccttcgtgcctctcggcatgacggattctttagtcattgtggaa
gaggacgattctgccatcataccctgccgcaccacggatccagacactgaagtaaccttg
cacaataacgggaggctggtgcctgcctcctacgacagcaggcagggcttcaacggaacc
ttcagtgtggggccttacatctgtgaggccaccgtcagagggaggacgttcaagaccagc
gagtttaacgtttatgccttgaaagccacgtcagaactgaatctggagatggacacacgc
cagactgtgtataaggcaggagaaacgatcgtggtgacctgcgccgtctttaacaatgag
gtggttgacctgcagtggacttaccctggagaggtgagaaacaaaggcatcaccatgctg
gaggagatcaaactcccgtccatcaaactggtgtacacgctgaccgtccccaaggccacg
gtgaaggacagtggagattatgaatgtgctgcccgccaggccacgaaagaggtcaaggaa
atgaagacagtcaccatttctgttcacgagaaaggcttcgtccagatcaggcccaccttt
ggccatctggaaactgtgaacctgcatcaggtcagagagttcgtggtggaggtgcaggcc
tacccgacccccaggatatcctggctgaaggacaacttgaccctgattgagaatctcact
gagatcaccaccgatgtgcagaggagccaggagacgaggtatcaaagcaaattaaagctg
atccgggctaaggaagaagacagcggccattataccattatagttcagaatgacgacgac
atgaagagctacacgtttgagctgtcaactctagttcctgcctccattctggagcttgtg
gatgaccaccatggctctggcgggggacagactgtgaggtgcacggctgaaggcacccct
cttccgaacatcgagtggatgatctgcaaggatattaagaaatgtaataatgacacttca
tggacagttttggccagcaacgtctcgaatattatcacggagttccaccagcgaggcagg
agtacagtggagggacgagtgtccttcgccaaggtggaagagaccatcgcagttcggtgc
ttggcaaagaacgaccttggcattgggaacagagagctgaagctggtggctcccaccctg
cgatctgagctcacggtggcggccgcggtgctggtgctgttggtgattgtcattgtctct
ctcattgtcctggttgtcatttggaagcagaaaccacggtatgaaattcgatggagggtc
attgagtcaatcagccctgatggacatgagtatatttatgtggaccccatgcagctgcct
tacgactccagatgggagttcccgagagatggactagtgcttggtcggatcttgggatcc
ggtgcatttgggaaagtggttgaaggcacagcttatggattaagccggtcccagcctgta
atgaaggtggctgtgaagatgctcaaacccacagccaggtctagtgagaagcaagctctc
atgtctgagctgaagataatgactcacttgggaccgcatctgaacattgtgaatttgctg
ggagcctgcaccaagtcaggccccatttacatcatcacagaatactgcttctatggggat
ttggtcaattacctgcataagaacagagatagcttcatgagccgacacccagagaagcca
aagaaagacctggacatctttggattgaatcctgcagatgagagtaccaggagttacgtg
attttatcttttgaaaacaatggtgactacgtggacatgaagcaggctgacaccacacag
tacgtgccaatgctggaaaggaaggaggtttccaaatactccgacatccagagatcgctg
tacgatcggccggcctcctataagaagaaatccatgctagactcagaagctaaaaacctc
ctttcggatgatgactccgagggtctgactttgctggacctactaagcttcacctaccaa
gtggcccgagggatggaatttttggcttcgaaaaattgtgtccaccgggacctggctgcc
cgcaacgtccttctggcgcaggggaaaatcgtgaagatctgtgacttcgggctggccaga
gacatcatgcacgattctaactacgtgtcaaagggcagcactttcctgcctgtgaagtgg
atggcacctgagagcatttttgacaacctctacaccacgctgagtgacgtctggtcttat
ggcgttctgctctgggaaatattctcccttggtggcacaccctaccctggcatgatggtt
gattctactttctacaataagatcaagagcggatacaggatggccaaacccgaccatgcc
accagtgaagtctatgagattatggtgcagtgctggaacagtgaacccgaaaagagaccc
tccttctaccacctcagcgagatagtggagaatctgctgcctggacagtacaaaaagagt
tatgaaaagattcacctggacttcctaaagagtgaccatccggctgtggcacgcatgcgt
gtggactctgacaacgcgtacatcggtgtcacttacaaaaatgaagaggacaagctgaag
gaatgggaaggtggcctggatgaacagagattgagcgcagatagtggctacatcattccc
ctgccagacattgaccctgttccagaggaggaagacctgggcaagaggaacagacacagc
tcgcagacttcggaagagagcgccatcgagacgggttccagtagttccactttcatcaag
agagaggacgagaccattgaggacatcgacatgatggatgatattggcatagattcctca
gacctggtggaggacagcttcctgtaa
DBGET
integrated database retrieval system
