Rattus norvegicus (rat): 81810
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Entry
81810 CDS
T01003
Gene name
Tgfbr2, TGF-beta_2, Tgfbr2T
Definition
(RefSeq) transforming growth factor, beta receptor 2
KO
K04388
TGF-beta receptor type-2 [EC:
2.7.11.30
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04010
MAPK signaling pathway
rno04060
Cytokine-cytokine receptor interaction
rno04068
FoxO signaling pathway
rno04144
Endocytosis
rno04218
Cellular senescence
rno04350
TGF-beta signaling pathway
rno04380
Osteoclast differentiation
rno04390
Hippo signaling pathway
rno04520
Adherens junction
rno04659
Th17 cell differentiation
rno04926
Relaxin signaling pathway
rno04933
AGE-RAGE signaling pathway in diabetic complications
rno05142
Chagas disease
rno05161
Hepatitis B
rno05166
Human T-cell leukemia virus 1 infection
rno05200
Pathways in cancer
rno05202
Transcriptional misregulation in cancer
rno05210
Colorectal cancer
rno05212
Pancreatic cancer
rno05220
Chronic myeloid leukemia
rno05225
Hepatocellular carcinoma
rno05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
81810 (Tgfbr2)
04350 TGF-beta signaling pathway
81810 (Tgfbr2)
04390 Hippo signaling pathway
81810 (Tgfbr2)
04068 FoxO signaling pathway
81810 (Tgfbr2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
81810 (Tgfbr2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
81810 (Tgfbr2)
09143 Cell growth and death
04218 Cellular senescence
81810 (Tgfbr2)
09144 Cellular community - eukaryotes
04520 Adherens junction
81810 (Tgfbr2)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
81810 (Tgfbr2)
09152 Endocrine system
04926 Relaxin signaling pathway
81810 (Tgfbr2)
09158 Development and regeneration
04380 Osteoclast differentiation
81810 (Tgfbr2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
81810 (Tgfbr2)
05202 Transcriptional misregulation in cancer
81810 (Tgfbr2)
09162 Cancer: specific types
05210 Colorectal cancer
81810 (Tgfbr2)
05212 Pancreatic cancer
81810 (Tgfbr2)
05225 Hepatocellular carcinoma
81810 (Tgfbr2)
05226 Gastric cancer
81810 (Tgfbr2)
05220 Chronic myeloid leukemia
81810 (Tgfbr2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
81810 (Tgfbr2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
81810 (Tgfbr2)
05161 Hepatitis B
81810 (Tgfbr2)
09174 Infectious disease: parasitic
05142 Chagas disease
81810 (Tgfbr2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
81810 (Tgfbr2)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
81810 (Tgfbr2)
Protein kinases [BR:
rno01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
81810 (Tgfbr2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ecTbetaR2
PK_Tyr_Ser-Thr
Pkinase
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
81810
NCBI-ProteinID:
NP_112394
RGD:
69651
Ensembl:
ENSRNOG00000013265
UniProt:
P38438
LinkDB
All DBs
Position
8q32
AA seq
567 aa
AA seq
DB search
MGRGLLRGLWPLHIVLWTRIASTIPPHVPKSVNSDLMAGDNSGAVKLPQLCKFCDVTLST
CDNQKSCMSNCSVTSICEKPQEVCVAVWRKNDKNITLETVCHDPKFTYHGFTLEDATSPT
CVMKEKKRAGETFFMCSCNTEECNDYIIFNEEYTTSSPDLLLVIIQVTGVSLLPPLGIAI
AVIAIFYCYRVHRQQKLSPSWESSKPRKLMDFSDNCAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYSSWKTEKDIFSDINLK
HENILQFLTAEERKTEMGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH
LHSDHTPCGRPKMPIVHRDLKSSNILVRSDLTCCLCDFGLSLGLSPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENMESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSRVRE
HPCVESMKDNVLRDRGRPEIPSFWLNHQGIQIVCETLTECWDHDPEARLTAQCVAERFSE
LEHPDRLSGRSCSQEKIPEDGSLNTTK
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
atgggtcgggggctgctccggggcctgtggccgctgcacatcgtcctgtggacgcgcatc
gccagcacgatcccgccgcacgttcccaagtcggttaacagcgatctgatggcgggtgac
aacagcggtgcggtcaagcttccacagctgtgcaagttttgcgacgtgacactgtccact
tgtgacaaccagaagtcttgcatgagcaactgcagcgtcacctccatctgtgagaagccg
caggaagtctgcgtggccgtgtggaggaagaacgacaagaacattactctggagaccgtt
tgccacgaccccaagttcacctaccacggcttcactctggaagatgccacttctcccacg
tgcgtcatgaaggaaaagaaaagggcgggcgagaccttcttcatgtgctcctgtaacaca
gaggagtgtaacgattacatcatctttaatgaagaatacaccaccagcagtcctgacctg
ttgctggtcattatccaagtgacgggcgtcagcctcctgcctccgctggggattgccata
gctgtcattgccatcttctactgttaccgtgtccaccggcagcagaagttgagcccctcc
tgggagagcagcaagccccggaagctcatggatttcagcgacaactgcgccatcatcctg
gaggacgaccgctctgacatcagctctacgtgcgccaacaacatcaaccacaatacggaa
ctgctgcccatcgagctggacacgctggtggggaagggccgcttcgccgaggtctacaag
gccaagctgaagcagaacacttcagagcagtttgagaccgtggctgtcaagatcttcccc
tacgaggaatactcctcgtggaaaacggagaaggacatcttctctgacatcaacctgaaa
cacgagaacatcctgcagttcctgacggccgaggagcggaagacggagatgggcaagcag
tactggctgatcacggcgtttcatgctaagggcaacctgcaggagtacctcactaggcac
gtcatcagctgggaggacctgcggaagctgggcagctccctggcccggggcatcgcccat
ctgcacagtgaccacactccttgtgggaggcccaagatgcccattgttcacagggacctc
aagagctctaacatcctagtaagaagcgatctaacctgttgcctgtgtgacttcgggttg
tccttgggcctgagccctactctgtctgtggatgacctggccaacagcgggcaggtggga
acagcgagatacatggccccggaagttctagaatccaggatgaatttggagaacatggag
tccttcaagcagacggatgtctactccatggctctagtactctgggaaatgacgtcgcgc
tgcaacgctgtgggagaagtgaaagattatgagcccccgtttggttccagagtgcgggag
cacccctgtgtggagagcatgaaagacaacgtgctgagagaccgaggacggcctgaaatc
cccagcttctggctcaaccaccagggcatccagatcgtgtgtgagacactgaccgagtgc
tgggaccacgaccccgaggcccgtctcacagcccagtgtgtggcagagcgcttcagtgaa
ctggagcacccagatagactctccgggaggagctgctcccaggagaagattccagaagac
ggctccctgaacactaccaaatag
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