Rhinopithecus roxellana (golden snub-nosed monkey): 104665875
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Entry
104665875 CDS
T03989
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00790
Folate biosynthesis
rro01100
Metabolic pathways
rro01240
Biosynthesis of cofactors
rro01523
Antifolate resistance
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
104665875 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
104665875 (FPGS)
Enzymes [BR:
rro01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
104665875 (FPGS)
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Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
104665875
NCBI-ProteinID:
XP_010366127
UniProt:
A0A2K6RE98
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Position
16:17044094..17065644
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AA seq
588 aa
AA seq
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MSRARNHLRAALSLAAASARGVTTQVAAQRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKRGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPTLEALEEGGPPLALGLEGE
HQRSNAALALQLAHCWLQRQDRHGAGELKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW
PGRTQVLRRGPLTWYLDGAHTPSSVQACVRWFRQALQGRERPSGSGPEVRVLLFNATGDR
DPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDK
EQASPDLWSAPSPEPGGPTSLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPVFQPPT
PPKGLLTHPVAHSGASVLHEAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcggaaccacctgcgcgccgctctatccctggcagcggcgtctgcgcgc
ggcgtaacgacccaggtcgcggcgcagcggggcttgagcgcgtggccggtgccgcaggag
cccagcatggagtaccaggatgccgtgcgcatgcttaataccctgcagaccaatgccggc
tacctggagcaggtgaagcgccagcggggtgacccccagacacagctggaagccatggaa
ctgtacctggcacggagtgggctgcaggtggaggacttggaccggctgaacatcatccac
gtcactgggacgaaggggaagggctccacttgtgccttcacagaatgtatcctccgaagc
tatggcctgaagacgggattctttagctctccccacctggtgcaggttcgggagcggatc
cgcatcaatgggcagcccatcagtcctgagctcttcaccaagtacttctggcgcctctac
caccggctggaggagaccaaggatggcagctgtgtctccatgcccccctacttccgcttc
ctgacactcatggctttccacgtcttcctccaagagaaggtggacctggcagtggtggag
gtgggcattggcggggcttatgactgcaccaacatcatcaggaagcctgtggtatgcgga
gtctcttctcttggcattgaccacaccagcctcctgggggacacggtggagaagatcgca
tggcagaaagggggcatctttaagcgaggtgtccctgccttcactgtgctccaacctgaa
ggtcccctggcagtgctgagggaccgagcccagcagatctcatgtcctctctacctgtgt
ccgacgctggaggccctggaggaaggggggccgccgctggccctgggcctggagggggag
caccagcggtctaacgccgccttggccttgcaactggcccactgctggctgcagcggcag
gaccgccatggtgccggggagctgaaggcatccaggccggggctcctgtggcagctgccc
ctggcacccgtgttccagcccacatcccacatgcggctcgggcttcggaacacggagtgg
ccgggccggacacaggtgctgcggcgcgggccccttacctggtacctggacggcgcgcac
acccccagcagcgtgcaggcttgcgtacgctggttccgacaggcgctgcagggccgagag
aggccgagcggcagtgggcccgaggttcgagtcttgctcttcaatgctaccggagaccgg
gacccggcggccttgctgaaactgttgcagccgtgccagtttgactatgccgtcttctgc
cccaacctgacagaggtgtcatccacaggcaatgcagaccaacagaacttcacggtgaca
ctggaccaggttctgctgcgctgcctggaacaccagcagcactggaaccacctggacaaa
gagcaggccagcccggacctctggagcgcccccagtccagagcctggtgggcccacatcc
ctgctgctggcgccccacccaccccacacctgcagcgccagctccctcgtcttcagctgc
atttcacatgccttgcaatggatcagccaaggccgagaccctgtcttccagccacccact
cccccaaagggcctcctcacccaccctgtggctcacagtggggccagcgtactccatgag
gctgctgccatccatgtgctggtcactggcagcctgcacttggtgggtggtgtcctgaag
ctgctggagcctgcactgtcccagtag
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