Streptomyces aquilus: EJC51_14060
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Entry
EJC51_14060 CDS
T07011
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
saqu
Streptomyces aquilus
Pathway
saqu00300
Lysine biosynthesis
saqu00550
Peptidoglycan biosynthesis
saqu01100
Metabolic pathways
saqu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
saqu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EJC51_14060
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EJC51_14060
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EJC51_14060
Enzymes [BR:
saqu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EJC51_14060
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
AZP17141
UniProt:
A0A3Q9BY36
LinkDB
All DBs
Position
complement(3045518..3046924)
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AA seq
468 aa
AA seq
DB search
MIALSLAEIASVVGGQTHDIPDPSVQVTGPVVRDSREVEPGSLFVAFVGERVDGHDFAAQ
VVEAGAAAVLASRPVGVPAIVVDDVQTAIGALAREVVRRLGATLVALTGSAGKTSTKDLI
AQVLQRKAPTVWTPGSLNNEIGLPLTALSATEETQFLVLEMGARGIGHIRYLAELTPPKI
GLVLNVGTAHIGEFGGREQIAQAKGELVEGLPEEGAAILNADDPLVRAMASRTKAKVILF
GESDEADVRAENVRLTDTGQPAFRLRTPSGDSDVTMRLYGEHHVSNALAAAAVAHELGMS
AEEIATALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALVAMGRGRRTWA
VLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEESVHVS
DAQAAVDLLRSELRPGDVVLVKASRSVGLESIAAALLATGAEGEVSAR
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctctctcgccgagatcgcctcagtcgtcggcgggcagacgcacgacata
ccggatccgtccgtccaggtcaccgggccggtcgtccgggactcccgagaagtggagccc
ggcagtctcttcgtcgccttcgtcggcgagcgcgtcgacggccacgacttcgcggcgcag
gtcgtcgaggcgggcgcggccgccgtgctggcgtcgcgccccgtcggcgtgcccgcgatc
gtcgtggacgacgtccagaccgcgatcggcgccctcgcgcgtgaggtcgtacgacggctc
ggcgcgaccctcgtcgccctgaccggctcggcgggcaagaccagcaccaaggacctcatc
gcccaggtgctccagcgcaaggcgccgacggtgtggacgccgggctcgctcaacaacgag
atcgggctgccgctgaccgccctgtccgccaccgaggagacgcagttcctcgtgctggag
atgggcgcccgcggcatcggccacatccgctacctcgccgaactgacgcccccgaagatc
ggcctcgtcctcaacgtcggcaccgcccacatcggcgagttcggcggtcgcgagcagatc
gcgcaggccaagggcgagctcgtggaagggctgccggaggagggcgcggcgattctcaac
gccgacgatcctctcgtacgggccatggcgtcccgtacgaaggcgaaggtgatccttttc
ggagagtccgacgaagcggacgtacgcgccgagaacgtgagactcacggacacgggacag
ccggccttcaggcttcgcacaccctccggtgacagcgacgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgtcc
gcggaagagatcgccaccgcgctctccgaggcgggctccctctcccgctggcggatggag
gtcaccgagcgcccggacggcgtgaccgtcgtcaacgacgcctacaacgccaaccccgaa
tccatgcgggccgcactgcgcgcgctcgtggccatgggccgggggcggcggacctgggcg
gtgctcggcaagatggccgagctcggggacgaggcgctcgccgagcacgacgcggtcgga
cggctcgccgtccggctcaacgtcagcaagctcgtcgcggtcgggggcagggaagcgtcc
tggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggcggtcgacctgttgcgcagcgagctgcgcccgggagacgtcgttctc
gtgaaggcgtcccgttcggtcggcctggagagcatcgccgcggcgctgctcgcgaccggt
gccgagggtgaggtttccgcccgatga
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