Streptomyces calvus: CD934_09230
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Entry
CD934_09230 CDS
T06819
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sast
Streptomyces calvus
Pathway
sast00290
Valine, leucine and isoleucine biosynthesis
sast00660
C5-Branched dibasic acid metabolism
sast01100
Metabolic pathways
sast01110
Biosynthesis of secondary metabolites
sast01210
2-Oxocarboxylic acid metabolism
sast01230
Biosynthesis of amino acids
Module
sast_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sast00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CD934_09230 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CD934_09230 (leuC)
Enzymes [BR:
sast01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CD934_09230 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CD934_09230 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
QDI68850
UniProt:
A0A514JND4
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All DBs
Position
complement(2280952..2282382)
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRTVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPMARPKTMAITVDGELPEGVTA
KDLILAIIARIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRPHAPQGEDWDAAVAYWKTLRTDDDAQFDAEVVIDAAELSPFVTWGTNPGQGAPL
SASVPDPASYEDASERLAAEKALEYMGLEAGQALRSIDVDTVFVGSCTNGRIEDLRAAAD
VIKGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLADADARTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctccgcaagagcggccgcaccgtgcgccgcctcgacctcaccatcgcgacc
gaggaccacaacacccccaccctcgacatcgacaagcccatcgccgacccggtctcccgg
gtccagctggagacgctgcgcaagaactgcgccgagttcggcgtccggctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtcgtcggcccgcagctgggcctcacccagccc
ggcatgacggtggtctgcggcgactcccacacctccacgcacggcgccttcggcggcctg
gccttcggcatcggcacctcccaggtcgagcacgtgctggccacgcagacgctgcccatg
gcccgcccgaagaccatggcgatcaccgtcgacggcgaactgcccgagggtgtcacggcc
aaggacctgatcctggcgatcatcgcgaggatcggcaccggcggcggccagggctacgtc
ctggagtaccgcggctccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcctacctcaagggccggccgcacgccccgcagggcgaggactgggacgcggccgtcgcc
tactggaagacgctcaggaccgacgacgacgcccagttcgacgccgaggtcgtcatcgac
gccgccgaactgtcgccgttcgtcacctggggcaccaaccccggccagggcgctccgctt
tcggcgtccgtccccgaccccgcttcgtacgaagacgcctcggagcggctcgccgccgaa
aaggccctggaatacatggggttggaggccggacaggcgctgcgctccatcgacgtcgac
accgtcttcgtaggttcctgcaccaacggccgcatcgaggacctgcgcgccgccgcggac
gtcatcaagggccgcaaagtcgccgacggcgtacggatgctggtcgtcccgggctcggcg
cgggtgggtctgcaggccgtctccgagggcctggacgtggtcttcaaggaggcgggtgcc
gagtggcggcacgccggctgctcgatgtgcctgggcatgaaccccgaccagctcgccccc
ggtgagcgctccgcctccacctccaaccgcaacttcgagggccggcagggcaagggcggc
cgcacccacctggtgtccccgcaggtcgccgccgccaccgcggtcctcggacacctcgcc
tccccggccgacctcgccgacgccgacgcccgtacgcccgctggagtctga
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